Aduru foforo a wɔde sa adwenemhaw: Nea ɛsɛ sɛ wuhu fa Auvelity ho

Adwenemhaw yɛ tebea a ɛma asetra yɛ sum kɛse na ɛyɛ adesoa. Sɛ worepere eyi a, ebia worennya ahotɔ kɛse sɛnea wususuw wɔ nnuru a wode redi dwuma mprempren no ho. Enti, seesei de, nnuru foforo nso aba de asa adwenemhaw. Ɛnnɛ yɛreka aduru bi a wɔfrɛ no `Auvelity` a ɛde anidasoɔ foforɔ a ɛte saa aba ho asɛm. Eyi yɛ aduru a wɔpenee so wɔ United States wɔ afe 2022 mu na wɔde sa Major Depressive Disorder.

Dɛn ne Auvelity? Ɔkwan bɛn so na ɛyɛ adwuma?

Sɛ yɛbɛka no tiawa a, `Auvelity` yɛ nnuru abien a wɔaka abom. Ɛno kyerɛ sɛ nnuru ahorow abien na ɛwɔ aduru koro no ara mu. Wɔn ne `dextromethorphan` ne `bupropion`. Fa no sɛ ɛyɛ adwuma te sɛ kuw. Nnipa baanu a wɔbom yɛ adwuma no nkutoo yɛ nnuru bɛboro biako.

• Bupropion : Eyi yɛ aduru a wɔde sa adwenemhaw dedaw . Ɛyɛ adwuma denam nnuru a ɛwɔ yɛn amemene mu a wɔfrɛ no `dopamine` ne `norepinephrine` a ɛka yɛn adwene a ɛma yɛkɔ soro no so.
• Dextromethorphan : Ebia wunim eyi yiye. Aduru yi wɔ ɔfe aduru bi mu. Nanso, wɔahu nso sɛ saa aduru yi ka nnuru a ɛwɔ amemene no mu a ɛne nkate wɔ abusuabɔ.

Enti, sɛ wɔka nnuru abien yi bom a , ɛboa kɛse ma wɔtew adwenemhaw ho sɛnkyerɛnne so sen bupropion nkutoo.

Ɔkwan bɛn so na wɔsɔɔ sɛnea aduru yi dii yiye hwɛe?

Ansa na wɔde aduru biara bɛma nkurɔfo no, wɔsɔ sɛnea asiane biara nni ho na etu mpɔn no hwɛ. Wɔayɛ ayaresabea nhwehwɛmu abien a ɛte saa ara wɔ `Auvelity` ho. Wɔ eyi mu no, wɔde ɔkwan titiriw bi dii dwuma de susuw sɛnea adwenemhaw no mu yɛ den. Wɔfrɛ no ``Montgomery-Asberg Depression Rating Scale (MADRS).`` Ɛte sɛ nsɛmmisa kratasin. Wobisa wo nsɛm 10 fa nneɛma te sɛ awerɛhow, nna ho haw, ne afobu nka ho na wɔma wo nkontaa. Wubetumi ama nkontabuo fi 0 kosi 60. Dodow a nkontabuo no kɔ soro no, dodow no ara na w’adwene mu yɛ wo naa. Sɛ nkontabuo no so tew bere a wɔanom aduru no akyi a, ɛkyerɛ sɛ yare no reyɛ yiye. Saa nhwehwɛmu ahorow yi de nnipa a wɔadi mfe 18-65 a wɔwɔ adwenemhaw a emu yɛ den kaa ho. Nanso, wɔamfa nnipa a wɔwɔ adwenemyare afoforo (te sɛ `bipolar disorder`, `psychotic disorder`), nnipa a asiane kɛse wom sɛ wobekum wɔn ho, ne nnipa a wɔwɔ akisikuru anhyɛ mu.

Dɛn na efi nhwehwɛmu ahorow no mu ba?

Nea afi mu aba no hyɛ nkuran ankasa. Aduru `Auvelity` no yɛɛ adwuma yiye wɔ adwenemhaw ho sɛnkyerɛnne so tew mu sen placebo ne `bupropion` nkutoo. Wei kyerɛ sɛ `MADRS` nkontabuo no sua wɔ wɔn a wɔnom `Auvelity` no mu sene wɔn a wɔnom nnubɔne foforɔ no.

So Auvelity betumi ne nnuru afoforo adi nkitaho? (Nnuru a Wɔde Di Dwuma) .

Eyi yɛ ɔfã a ɛho hia paa . Yiw, Auvelity betumi ne nnuru afoforo a worenom no bi adi nkitaho. Enti, ɛsɛ sɛ woka nnuru a worenom nyinaa ho asɛm kyerɛ wo duruyɛfo, a nnuru a wɔtɔn, vitamin, ne Ayurvedic nnuru mpo ka ho.

Tebea a asiane wom a wɔfrɛ no Serotonin Syndrome no

Sɛ wɔde Auvelity ne nnuru afoforo a ekum adwenemhaw a ɛma serotonin dodow kɔ soro nom a, ebetumi ama amemene mu nnuru a wɔfrɛ no serotonin no akɔ soro a wɔmpɛ. Wɔfrɛ eyi sɛ Serotonin Syndrome. Eyi yɛ tebea a egye ntɛmpɛ a ɛde nkwa to asiane mu. Sɛ wuhu saa sɛnkyerɛnne ahorow yi a, kɔ ayaresabea Emergency Department (ETU) a ɛbɛn wo ntɛm ara. Ɛsɛ sɛ nnafua 14 nsonsonoe da MAOI nnuru a ekum adwenemhaw a wɔnom ne Auvelity a wɔnom ntam.

Nsunsuanso afoforo

• Na nnuru a ɛma dopamine yɛ kɛse: `Auvelity` ma dopamine kɔ soro wɔ amemene no mu. Enti sɛ wɔde ka nnuru afoforo a ɛma dopamine yɛ kɛse (te sɛ nnuru bi a wɔde sa Parkinson yare) ho a, dopamine dodow betumi akɔ soro dodo, na ama obi ho atɔ no, ne ho popo, .Ebia nantew bɛyɛ den.
• Wɔ Nsã ho: Ɛsɛ sɛ wɔkwati nsa a wɔnom anaasɛ wɔto ano hye kɛse bere a wɔrenom `Auvelity` no. Sɛ wɔde abien no bom a , ɛma asiane a ɛwɔ hɔ sɛ obi benya akisikuru no yɛ kɛse .
• Koma mu nnuru: Ebia Auvelity bɛsakra sɛnea koma mu nnuru te sɛ digoxin yɛ adwuma yiye. Ɛho hia sɛ wobɔ wo duruyɛfo amanneɛ wɔ eyi ho.
• Nnuru afoforo a mmerɛbo no sɛe: Yɛn mmerɛbo te sɛ adwumayɛbea a ɛbubu nnuru. Auvelity ka enzyme nhyehyɛe a wɔfrɛ no ``cytochrome P450 (CYP450)`` wɔ saa nhyehyɛe yi mu. Eyi betumi asakra ɔkwan a nnuru afoforo a wonom no yɛ adwuma.

Ɔkwan bɛn so na wɔde saa aduru yi di dwuma na dɛn ne nea efi mu ba?

`Auvelity` yɛ aduru a wɔkyerɛw ma obi nkutoo. Dodow a wɔtaa de ma ne aduru biako da biara wɔ nnansa a edi kan no mu, afei aduru biako mprenu da biara (wɔn ntam nnɔnhwerew 8).

Nneɛma bɔne a ebetumi aba ne nneɛma a ɛsɛ sɛ wohwɛ yiye wɔ ho

• Mogya mmoroso: Ebia wo duruyɛfo bɛka akyerɛ wo sɛ hwɛ wo mogya so daa.
• Adwene a ɛyɛ basaa: Saa aduru yi betumi ama obi adwenem ayɛ no yaw. Enti, hwɛ yiye bere a woreka kar, wode mfiri redi dwuma, na woreyɛ nnwuma a ebetumi ama woahwe ase no.
• Nkɛntɛnso a enya wɔ aniwa so: Sɛ w’ani yɛ wo yaw, wo ho yɛ kɔkɔɔ, anaa nsakrae a ɛba w’ani so a, ka kyerɛ wo duruyɛfo.
• Suban mu nsakrae: Ebia nnipa binom benya adwene mu basaa, wobehu anaa wɔbɛte nneɛma a enni hɔ (nsusuwii a ɛyɛ nwonwa), na ɛyɛ den sɛ wobehu nokwasɛm.
• Akisikuru: Sɛ wɔde ka nsa ho a, asiane yi kɔ soro. Sɛ wote akisikuru bere a worenom aduru no a, gyae aduru no nom ntɛm ara na ka kyerɛ wo duruyɛfo.
• Ɛnanom a wɔyem ne wɔn a wɔma nufu: Saa aduru yi nyɛ nea asiane biara nni ho bere a wɔyem anaa wɔma wɔn nufu. Sɛ woreyɛ nhyehyɛe sɛ wubenyinsɛn, woanyinsɛn, anaa worenom nufu a, ka kyerɛ wo duruyɛfo ntɛm ara.

Nhumu titiriw a ɛfa adwene a ɛne sɛ obekum ne ho ho

Te sɛ nnuru bi a wɔde sa adwenemhaw no, Auvelity betumi ama asiane a ɛwɔ hɔ sɛ wobekum wɔn ho adwene anaa nneyɛe wɔ nnipa binom mu no ayɛ kɛse kakra , titiriw wɔ ayaresa no mfiase.Eyi abu so kɛse wɔ mmerante ne mmabaa mu. Sɛ wo anaa w’abusua mu obi renya saa nsusuwii yi a, mma wo nko ara.

• Frɛ 1926 (National Mental Health Helpline) ntɛm ara.
• Sɛ ɛnte saa a, kɔ ayaresabea a ɛbɛn wo no Emergency Treatment Unit (ETU).
• Ka eyi ho asɛm kyerɛ wo duruyɛfo ntɛm ara.

Eyi nyɛ biribi a ɛsɛ sɛ wɔde sie. Ɛho hia paa sɛ wubenya mmoa ntɛm. Auvelity, adwenemhaw, adwenemyare, nnuru a ekum adwenemhaw, dextromethorphan, bupropion, serotonin syndrome, nnuru a ekum adwenemhaw, nea efi mu ba