So woate Chronic Lymphocytic Leukemia (CLL) ho asɛm pɛn? Momma yɛnka ho asɛm nkɔ akyiri!

So ɛtɔ mmere bi a wote nka sɛ woabrɛ paa ara kwa? Anaasɛ wotaa nya atiridii? So wowɔ akuru nketenkete a ɛte sɛ nea ɛwɔ wo kɔn, wo nsateaa, anaa wo srɛ so? Eyinom betumi ayɛ Chronic Lymphocytic Leukemia, anaa CLL tiawa ho sɛnkyerɛnne. Nanso mma ɛnhaw wo, efisɛ sɛ wowɔ saa sɛnkyerɛnne yi nyinaa a, ɛnkyerɛ sɛ wowɔ saa yare yi. Nanso ɛho hia yiye sɛ wobɛma w’ani aku nneɛma a ɛte sɛɛ ho. Enti momma yɛnka CLL ho asɛm wɔ ɔkwan a ɛnyɛ den so nnɛ, ɛyɛ?

Dɛn ne mogya mu nkwammoaa a ɛma mogya tu a enni sabea (CLL)? Sɛ yɛbɛka no tiawa a...

Chronic lymphocytic leukemia (CLL) yɛ mogya mu kokoram bi . Ɛyɛ mogya mu kokoram a abu so sen biara wɔ mpanyimfo mu. Wɔyɛ mogya mu nkwammoaa wɔ nnompe mu ntini mu. Saa tebea yi ba bere a lymphocytes, mogya mu nkwammoaa fitaa a ɛte apɔw bi a ɛwɔ nnompe mu ntini mu no yɛ nea ɛnteɛ, a ɛkyerɛ sɛ ɛsakra na ɛbɛyɛ kokoram no. Saa kokoram nkwammoaa yi dɔɔso a wontumi nni so, na ɛhyɛ mogya mu nkwammoaa a ɛte apɔw ne mogya nkwammoaa a ɛboa ma mogya tu no mu.

CLL taa ba nnipa a wɔadi boro mfe 65. Nanso, ɛtɔ mmere bi a ebetumi aba nnipa a wonnii mfe 30. Nea ɛsen saa no, nnipa binom betumi anya CLL a wonni sɛnkyerɛnne biara . Nnipa pii hu tebea no ho asɛm bere a wɔreyɛ wɔn mogya mu nhwehwɛmu ahu tebea foforo anaa bere a wɔreyɛ aduruyɛ mu nhwehwɛmu a wɔyɛ daa afe biara no.

Mprempren, wonni aduru biara a wɔde sa CLL. Nanso ɛno nyɛ ade a ɛhaw adwene. Wɔ mfe du a atwam no mu no, nnuruyɛfo ayɛ ayaresa foforo a ebetumi asiw CLL so na ama ayɛ mmerɛw . Saa ayaresa ahorow yi ama nnipa a wɔwɔ CLL no atra ase akyɛ kɛse.

Dɛn ne CLL ahorow atitiriw no?

Mogya mu nkwammoaa fitaa ahorow atitiriw abien na ɛwɔ yɛn nipadua mu, a wɔfrɛ no lymphocytes. CLL betumi anya nkɔso wɔ saa ahorow abien yi mu biako pɛ mu.

• B-lymphocytes (B-cells): Eyinom ne nkwammoaa a ɛma nipadua no tumi ko tia nyarewa, protein bi a ehu mmoawa, mmoawa, mmoawa, ne kokoram nkwammoaa mpo na ɛko tia.
• T-lymphocytes (T-cells): Eyinom hwɛ sɛnea yɛn nipadua no tumi a ɛko tia nyarewa no yɛ adwuma. Wohu nkwammoaa a ɛnteɛ te sɛ kokoram nkwammoaa nso na wɔsɛe no tẽẽ.

CLL a abu so sen biara ne B-cell CLL . Tebea bi wɔ hɔ a ɛfa ho a ɛka T-nkwaboaa, a wɔfrɛ no T-cell prolymphocytic leukemia (PLL). Nanso, nnipa a wɔwɔ PLL no nya yare no ho sɛnkyerɛnne ntɛmntɛm sen nnipa a wɔwɔ B- cell CLL.

Wɔfrɛ tebea yi sɛ CLL abu so dɛn?

Nokwarem no, mogya mu kokoram a enni sabea (CLL) yɛ mogya mu kokoram ahorow a abu so wɔ mpanyimfo mu no mu biako. Wɔ United States no, yare no ka nnipa 100,000 biara mu bɛyɛ 5. Amerika Kokoram Fekuw no bu akontaa sɛ nnipa foforo bɛyɛ 18,700 na wɔanya CLL wɔ afe 2023 nkutoo mu. Sɛ yɛbɛma eyi ayɛ nea ɛfata a, wɔhwɛ kwan sɛ wɔbɛbɔ ahurututu mu kokoram (kokoram a ɛtaa ba no mu biako) foforo bɛboro 238,000 ho amanneɛ wɔ afe 2023. Enti, bere a ebia ɛte sɛ nea CLL ntaa mma saa no, ɛyɛ mogya mu kokoram ahorow a abu so sen biara no mu biako.

Dɛn ne CLL ho sɛnkyerɛnne ahorow?

Sɛnea yɛadi kan aka no, nnipa binom betumi anya CLL a wonni sɛnkyerɛnne biara . Ebetumi agye asram anaa mfe mpo ansa na yare no ho sɛnkyerɛnne ada adi. Nsɛnkyerɛnne a ɛtaa ba ne:

• Ɔbrɛ: CLL betumi aka wo mogya mu nkwammoaa kɔkɔɔ, na ama mogya atɔ wo mu. Ɔbrɛ yɛ mogya a ɛtɔ kɔ nipadua mu ho sɛnkyerɛnne a ɛtaa ba.
• Atiridii: Atiridii yɛ sɛnkyerɛnne a ɛkyerɛ sɛ obi anya ɔyare mmoawa. Esiane sɛ CLL ka mogya mu nkwammoaa fitaa a ɛte apɔw nti, ɛda adi sɛ wubenya nyarewa.
• Ntini a ɛho ahonhon wɔ kɔn, abasa, asen, anaa yafunu mu.
• Anadwo fifiri a ɛba.
• Mu duru a ɛso tew a wontumi nkyerɛkyerɛ mu.
• Ɛyaw anaa wo mpampam ase a wote nka sɛ wo ho ayɛ wo ma: CLL betumi aka wo mmerɛbo anaa wo akyi berɛmo. Sɛ kokoram nkwammoaa boaboa ano wɔ saa akwaa ahorow yi mu a, ebetumi ahuru.

Dɛn nti na CLL nya nkɔso? Dɛn ne nneɛma a ɛde asiane ba?

Chronic lymphocytic leukemia (CLL) ba bere a nkwaadɔm mu nsakrae, anaa nsakrae bi ba yɛn chromosomes ne awosu mu nkwaadɔm mu wɔ yɛn nkwa nna mu no. Nanso, nnuruyɛ mu nhwehwɛmufo da so ara nnim nea ɛde nsakrae yi ba. Nanso, wɔahu asiane ahorow pii a ebetumi aka no:

• Abusua abakɔsɛm: Nhwehwɛmu ada no adi sɛ sɛ w’abusuafo a wɔbɛn wo no mu biako, kyerɛ sɛ, wo maame, wo papa, wo nuanom, anaa wo mma wɔ CLL a, asiane a ɛwɔ hɔ sɛ wubenya CLL no betumi akɔ soro mmɔho abien kosi anan.
• Mfe a wɔadi: Sɛ wɔkyekyem pɛpɛɛpɛ a, ayarefo no adi bɛyɛ mfe 71 bere a wohu sɛ wɔwɔ CLL no.
• Ɔbarima ne Ɔbea Nna: Mmarima taa nya CLL.
• Agent Orange a Wɔde Di Dwuma: Nhwehwɛmu ada no adi sɛ abusuabɔ bi da Agent Orange, nnuru bi a wɔde dii dwuma wɔ Vietnam Ko no mu, ne CLL ntam.
• Monoclonal B-nkwaboaa mu nkwammoaa a ɛma mogya tu:Wɔ tebea yi mu no, wowɔ B-cell biako pɛ wɔ wo mogya mu sen sɛnea ɛte daa. Sɛ wowɔ saa tebea yi a, asiane ketewaa bi wɔ hɔ sɛ wubenya CLL.

Dɛn ne nsɛnnennen a ebetumi afi CLL mu aba?

CLL ka wo mogya mu nkwammoaa kɔkɔɔ, mogya mu nkwammoaa fitaa, ne mogya mu nkwammoaa kɔkɔɔ. Susuw ho hwɛ, mogya mu nkwammoaa kɔkɔɔ de mframa pa kɔ nipadua no mu nyinaa. Mogya mu nkwammoaa fitaa bɔ yɛn ho ban fi nyarewa ho. Ntini mu nkwammoaa a ɛma mogya tu boa ma mogya tu. Enti, sɛ wohwere mogya mu nkwammoaa ne mogya nkwammoaa a ɛte apɔw yi a, wubetumi anya nsɛnnennen te sɛ:

• Lymphoma: Nnipa a wɔwɔ CLL no mu 2% kosi 10% betumi anya kokoram bi a wɔfrɛ no lymphoma.
• Wo honam ani kokoram, ahurututu mu kokoram, anaa akyi berɛmo mu kokoram: CLL ma wo nipadua mu tumi a ɛko tia nyarewa no yɛ mmerɛw, na ɛmma entumi mmɔ wo ho ban mfi ntuafo a kokoram nkwammoaa ka ho ho. Eyi betumi ama asiane a ɛwɔ hɔ sɛ wubenya kokoram ahorow afoforo no ayɛ kɛse.
• Mogya a ɛtɔ kɔ nipadua mu: Mogya a ɛtɔ kɔ nipadua no mu betumi aba bere a mogya mu nkwammoaa kɔkɔɔ a ɛdɔɔso a ɛbɛma mframa pa akɔ nipadua no nyinaa mu no.
• Thrombocytopenia: CLL betumi aka wo mogya nkwammoaa a ɛma mogya no. Eyi betumi ama mogya atu.
• Nyarewa a ɛtaa ba: Sɛ wunni mogya mu nkwammoaa fitaa a ɛte apɔw a ɛdɔɔso a, ɛda adi sɛ wubenya ɔyare mmoawa, fungal, anaa mmoawa.
• Nyarewa a nipadua no tumi ko tia nyarewa: Nnipa binom a wɔwɔ CLL betumi anya tebea horow te sɛ autoimmune hemolytic anemia.

Ɔkwan bɛn so na wohu CLL?

Sɛ wokɔ oduruyɛfo nkyɛn a, obebisa wo wo yare no ho sɛnkyerɛnne. Afei, wɔbɛyɛ nipadua mu nhwehwɛmu na ebia wɔbɛhyɛ sɛ wɔnyɛ sɔhwɛ ahorow bi te sɛ:

• Mogya dodow a edi mũ (CBC) ne nsonsonoe: Saa nhwehwɛmu yi kyerɛ mogya mu nkwammoaa kɔkɔɔ, mogya mu nkwammoaa fitaa, ne mogya mu nkwammoaa dodow a ɛwɔ wo mogya mu. Ɛsan nso hwɛ sɛnea hemoglobin (protein a ɛde mframa pa kɔ wo mogya mu) dodow a ɛwɔ wo mogya mu nkwammoaa kɔkɔɔ mu no mu.
• Mogya a wɔde gu nipadua no akyi: Aduruyɛ mu nhwehwɛmubea ho ɔbenfo bi de afiri a wɔde hwɛ nneɛma nketenkete hwehwɛ wo mogya mu nkwammoaa mu hwɛ sɛ kokoram nkwammoaa wɔ hɔ anaa.
• Flow cytometry: Saa lab nhwehwɛmu yi betumi ama woanya wo mogya mu nkwammoaa ho nsɛm pii. Wɔ CLL mu no, wɔde kyerɛ sɛ ebia CLL nkwammoaa wɔ wo mogya mu nkwammoaa fitaa mu anaa.
• Awosu mu nhwehwɛmu:Nnuruyɛfo de nhwehwɛmu te sɛ fluorescent in situ hybridization (FISH) ne immunoglobulin heavy chain (IGHV) di dwuma de hwehwɛ wo nkwaboaa ne awosu mu nkwaadɔm mu. Sɛ wɔte nsakrae a aba wɔ saa chromosomes ne awosu mu nkwaadɔm yi mu ase a, ɛboa nnuruyɛfo ma wosi sɛnea wɔbɛsa CLL ho gyinae.

CLL no afã horow

Nnuruyɛfo kyerɛ baabi a kokoram bi bɛkɔ de ayɛ ayaresa ho nhyehyɛe na wɔhyɛ nkɔmhyɛ a ɛbɛba ho nkɔm. Akwan titiriw abien na wɔfa so yɛ CLL: Rai staging nhyehyɛe ne Binet staging nhyehyɛe .

Ɛtɔ da bi a, sɛ wokenkan saa afã horow yi wɔ akontaahyɛde ne nkyerɛwde mu a, ebia wobɛte ehu nka kakra na wo ho nyɛ wo dɛ. Ebia wubesusuw mpo sɛ, "So eyi ne sɛnea wɔka me yare no ho asɛm wɔ nnuru a wɔde yɛ aduan mu?" Nnuruyɛfo te saa asɛm no ase. Sɛ wo nnim nea wɔreka no pefee, anaasɛ ɛyɛ adesoa ma wo a, yɛsrɛ wo bisa wo duruyɛfo ma ɔnkyerɛkyerɛ sɛnea saa stage nhyehyɛe yi fa wo tebea no ho no mu.

Rai staging nhyehyɛe

Saa kwan yi kyekyɛ CLL mu sɛnea ɛbɛyɛ yiye sɛ ɛbɛkɔ so asɛe ne sɛ ebia ɛho behia sɛ wɔsa yare anaa:

• Asiane a ɛba fam (kan no na wɔfrɛ no Rai stage 0): Wowɔ lymphocytosis (lymphocytes dodow a ɛkɔ soro), na mogya mu nkwammoaa fitaa a ɛnteɛ wɔ mogya ne/anaasɛ nnompe mu ntini mu.
• Asiane a ɛwɔ mfinimfini (kan no na wɔfrɛ no Rai stage I anaa stage II): Wowɔ lymphocytosis, lymph nodes a ahonhon, ne wo akyi berɛmo ne/anaasɛ mmerɛbo a ayɛ kɛse.
• Asiane kɛse (kan no na wɔfrɛ no Rai Stage III): Wowɔ mogya a ɛtɔ kɔ nipadua mu anaasɛ thrombocytopenia (platelet dodow a ɛba fam).

Binet staging nhyehyɛe

Saa kwan yi gyina wo mogya mu nkwammoaa ne mogya nkwammoaa dodow, ne mmeae dodow a ntini a ɛho ahonhon wɔ wo nipadua mu so:

• Ɔfã A: Wunni mogya a ɛtɔ (mogya mu nkwammoaa kɔkɔɔ dodow a ɛba fam) anaasɛ mogya mu nkwammoaa a ɛba fam. Nanso, anyɛ yiye koraa no, wo nipadua no mu ntini a ɛho ahonhon wɔ mmeae abien. Sɛ nhwɛso no, ebia wo kɔn ne wo srɛ mu ntini a ahonhon.
• Ɔfã B: Ntini a ɛho ahonhon wɔ nipadua no mmeae abiɛsa, anaasɛ mmerɛbo anaa akyi berɛmo no ahonhon. Nanso, mogya a ɛtɔ kɔ nipadua no mu nni hɔ, na mogya mu nkwammoaa a ɛwɔ mogya mu no dodow yɛ nea ɛfata.
• Ɔfã C: Wowɔ mogya a ɛtɔ kɔ wo nipadua mu ne ntini a ɛho ahonhon wɔ wo nipadua no mmeae abiɛsa anaa nea ɛboro saa.

Ɔkwan bɛn so na wɔsa CLL?

Wogyina wo yare no ho sɛnkyerɛnne ne nea efi nhwehwɛmu mu ba so na ɛkyerɛ ayaresa a wubetumi apaw. Sɛ nhwɛso no, sɛ wowɔ CLL a edi kan a, ebia wo duruyɛfo bɛkamfo "ahwɛyiye a wobɛtwɛn/ahwɛyiye a ɛyɛ nnam."Wubetumi de ɔkwan a wɔfrɛ no "monitoring" no akɔ. Nea ɛka eyi ho ne sɛ wobɛhwɛ w’akwahosan nyinaa, wo yare no ho sɛnkyerɛnne, ne nea efi sɔhwɛ mu ba no so yiye a wunfi ayaresa ase.

Nea efi awosu mu nhwehwɛmu mu ba nso betumi aka ayaresa ho gyinaesi ahorow. Sɛ nhwɛso no, awosu mu nsakrae bi betumi akyerɛ sɛ wo tebea no betumi asɛe ntɛmntɛm, anaasɛ ebia CLL ayaresa a wɔtaa de di dwuma no rentumi nyɛ adwuma yiye sɛnea wɔhwɛɛ kwan no.

Ayaresa a wɔtaa de sa CLL ne ayaresa a wɔde wɔn ani asi so ne nnuru a wɔde sa yare . Ɛtɔ mmere bi a wɔde mframa a wɔde sa yare di dwuma de tew CLL ho sɛnkyerɛnne so. Saa ayaresa yi mu biara betumi de ɔhaw ahorow aba. Wo duruyɛfo bɛkyerɛkyerɛ mfaso a ɛwɔ so, nea efi mu ba, ne ɔhaw ahorow a ebetumi aba bere tenten a ɛwɔ ayaresa a woregye no so no mu pefee.

Ayaresa a wɔde wɔn ani asi so

Saa ayaresa yi yɛ adwuma denam kokoram nkwammoaa a wɔde wɔn ani si so so. Wɔ lymphocytic leukemia a enni sabea mu no, saa ayaresa yi yɛ adwuma denam mogya mu nkwammoaa fitaa a kokoram wom a esiw nyin no so. Ayaresa ahorow bi a wɔde wɔn ani asi so kunkum kokoram nkwammoaa a ɛnpira nkwammoaa a ɛte apɔw. Nnuru a wɔde yɛ eyi no bi ne:

• Bruton’s tyrosine kinase (BTK) inhibitor therapy: Saa ayaresa yi siw enzyme bi a ɛboa ma B-nkwaboaa ma wɔyɛ mogya mu nkwammoaa fitaa pii no ano. Nhwɛso ahorow: ibrutinib (Imbruvica®) , acalabrutinib (Calquence®) , ne zanubrutinib (Brukinsa ®) .
• BCL2 inhibitor therapy: Aduru venetoclax (Venclexta®) siw protein bi a wɔfrɛ no BCL2 a wohu wɔ mogya mu kokoram nkwammoaa mu, a CLL nkwammoaa ka ho no ano. Saa ayaresa yi betumi akunkum mogya mu kokoram nkwammoaa anaasɛ ama wɔayɛ mmerɛw kɛse wɔ nnuru afoforo a wɔde ko tia kokoram ho.
• Monoclonal antibody therapy: Eyi yɛ aduru bi a ɛma nipadua no tumi ko tia nyarewa. Monoclonal antibodies yɛ antibody bi a wɔyɛ wɔ aduruyɛdan mu. Wɔma kokoram nkwammoaa nyin anaasɛ wokum kokoram nkwammoaa. Nhwɛso ahorow: rituximab (Rituxan®) ne obinutuzumab (Gazyva®) .

Nnuru a wɔde sa yare

Ebia wo duruyɛfo de nnuru a wɔde sa yare bedi dwuma sɛ aduru titiriw a wɔde sa mogya mu nkwammoaa a ɛma mogya tu a enni sabea. Nnuru a wɔtaa de sa CLL no bi ne:

• Fludarabine (Fludarabine - Fludara®) a ɛwɔ nipadua no mu.
• Klorambucil (Klorambucil - Leukeran®) .
• Cyclophosphamide (Cytoxan®) a wɔde yɛ aduru a wɔfrɛ no .
• Bendamustine (Bendamustine - Treanda®) a ɛwɔ aduruyɛ mu.

Nnuru a ɛko tia nyarewa

Saa ayaresa kwan yi yɛ adwuma denam wo nipadua mu tumi a ɛko tia nyarewa a ɛsan ba anaasɛ ɛhyɛ mu den, na ɛboa ma kokoram nkwammoaa sɛe anaasɛ ɛma wɔn nyin brɛoo no so.

Wɔ CLL a ennyaa nnuru a wɔde sa yare no ho dwuma, CLL asan aba (a ɛsan ba bio), anaasɛ ɛreyɛ kɛse ho no, nnuruyɛfo betumi de aduru a wɔde sa yare a ɛko tia nyarewa a wɔfrɛ no lenalidomide (Revlimid®) adi dwuma .

Aduruyɛ mu nhwehwɛmufo nso reyɛ chimeric antigen receptor (CAR-T) ayaresa a wɔde ma CLL ayarefo a wɔnyɛ wɔn ade wɔ ayaresa a wɔtaa de di dwuma ho no ho ade.

Bere tenten ahe na wubetumi de CLL atra ase?

Mpɛn pii no, mogya mu kokoram a enni sabea (CLL) kɔ so nkakrankakra. Wubetumi ne CLL atra ase mfe pii ansa na woanya yare no ho sɛnkyerɛnne. Sɛ sɛnkyerɛnne ahorow no da adi pɛ a, nnuruyɛfo wɔ ayaresa ahorow a etu mpɔn yiye a ebetumi ama CLL ayɛ mmerɛw . Mpɛn pii no, saa yare a efi CLL mu no gyae mfe pii ansa na yare no asan aba. Nanso, ebia wo duruyɛfo bɛkamfo ayaresa afoforo a ebetumi ama CLL ayɛ mmerɛw bio. CLL ntumi nsa koraa, nanso nnipa a wɔwɔ yare no betumi atra ase akyɛ na wɔadi mũ.

Ɔman Kokoram Asoɛe no bu akontaa sɛ ayarefo a wɔwɔ CLL no mu 87.9% te ase wɔ mfe anum akyi bere a wɔahu sɛ wɔanya bi no. Nanso, sɛ woresusuw nkwagye dodow yi ho a, ɛho hia sɛ yɛkae sɛ eyinom yɛ akontaabu a egyina ayarefo kuw kɛse bi a wɔwɔ CLL osuahu so. Nneɛma pii betumi aka saa nkwagye dodow yi, a w’akwahosan nyinaa, baabi a wo yare no wɔ bere a wohui, ne sɛnea wo yare no yɛ n’ade yiye wɔ ayaresa ho ka ho. Sɛ wowɔ nsɛmmisa bi a, bisa wo duruyɛfo nea wobɛhwɛ kwan a egyina wo tebea so.

Dɛn na ɛkɔ so wɔ CLL no awiei?

Asɛmfua "end-stage" kyerɛ sɛ ayaresa ahorow no ntumi nyɛ adwuma yiye bio wɔ CLL yare no ano aduru anaasɛ wogyae mu. Saa bere no, ebia wubenya nyarewa a ɛde wo nkwa to asiane mu anaa mogya a wuntumi nhyɛ so a ebia nnuruyɛfo rentumi nsa.

So wobetumi asiw tebea yi ano?

Mprempren ɔkwan biara nni hɔ a wonim a wɔbɛfa so asiw CLL ano.

Sɛ wo ne CLL bɛtra a, ɛte dɛn?

Egyina wo tebea no so. Wubetumi anya CLL a wunhu sɛnkyerɛnne biara. Sɛ wowɔ sɛnkyerɛnne ahorow a, ayaresa ahorow wɔ hɔ a wɔde bɛtew so na wɔadi yare no ho dwuma. Nanso, yare no renkɔ koraa.

Nyansahyɛ ahorow bi a ebetumi aboa wo bere a wo ne CLL te ni:

• Bɔ wo ho ban fi nyarewa ho:Nnipa a wɔwɔ CLL no wɔ asiane kɛse mu sɛ wobenya nyarewa. Nyarewa bi betumi de nkwa ato asiane mu. Bisa wo duruyɛfo no nnuru a wɔde bɔ wo ho ban a ɛfata wo ho asɛm.
• Hwɛ w’akwahosan nyinaa yiye: Ebia asiane kɛse wom sɛ wubenya honam ani kokoram, ahurututu mu kokoram, anaa akyi berɛmo mu kokoram. Bisa wo duruyɛfo no kokoram nhwehwɛmu ho nhwehwɛmu.
• Di adwennwen ho dwuma: Nnipa pii a wɔwɔ CLL no fa kyinhyia ahorow a ɛma ɛyɛ mmerɛw na ɛsan ba bio. Bere a yare no kɔ so no, ebia wobɛte dadwen ne ehu nka. Sɛ saa a, bisa wo duruyɛfo nhyehyɛe anaa nnwuma a ebetumi aboa wo ma woadi w’adwennwen so ho asɛm.
• Di aduan pa: CLL ho sɛnkyerɛnne ahorow bi betumi ama w’ani nnye aduan ho. Wo ne wo duruyɛfo nkasa mfa afotu a wubenya afi aduannuru ho ɔbenfo hɔ ho. Sɛ w’akɔnnɔ ye a, bɔ mmɔden sɛ wubedi aduan a ɛkari pɛ a protein a ɛnyɛ den, aburow a wɔayam, nnuaba ne nhabannuru, ne srade a ahoɔden wom ka ho. Eyi betumi ama w’akwahosan nyinaa atu mpɔn.
• Apɔw-mu-teɛteɛ: Apɔw-mu-teɛteɛ boa wo ma wudi adwennwen so na ɛma w’ani gye.
• Ahomegye: CLL betumi ama woate nka sɛ woabrɛ kɛse. Gye w’ahome bere a wote nka sɛ ɛsɛ sɛ wohome no.
• Hu nea wobɛhwɛ kwan: Nimdeɛ yɛ tumi. Bisa wo duruyɛfo ma ɔmma wo nsɛnkyerɛnne a ɛkyerɛ sɛ ebia wo tebea no reyɛ kɛse. Sɛ saa a, ebia wo duruyɛfo bɛkamfo ayaresa afoforo a ebetumi aboa ma woadi wo CLL ho dwuma yiye.

Nsɛm bɛn na ɛsɛ sɛ mibisa me duruyɛfo?

Ebia wobɛpɛ sɛ wubisa nsɛm te sɛ eyinom:

• Lymphocytic leukemia a enni sabea bɛn na mewɔ?
• Minni sɛnkyerɛnne biara. Bere bɛn na ɛsɛ sɛ mifi ase sa yare?
• Ayaresa ahorow bɛn na mewɔ?
• So ɛsɛ sɛ mefa ayaresa daa?
• So ayaresa bɛma me tebea no agyae?

Nea etwa to no, nneɛma a ɛsɛ sɛ wokae (Take-Home Message) .

Chronic lymphocytic leukemia (CLL) yɛ mogya mu kokoram bi a ɛtaa ba mpanyimfo mu. Wubetumi anya saa tebea yi mfe pii a wunhu sɛnkyerɛnne biara. Sɛ wowɔ CLL a, ebia ɛho renhia sɛ wufi ase sa yare ntɛm ara. Ɛwom sɛ nnuruyɛfo ntumi nsa koraa de, nanso ayaresa ahorow bi wɔ hɔ a ebetumi ama CLL ho sɛnkyerɛnne ahorow no afi hɔ na ama yare no agyae . Nnipa binom a wɔwɔ CLL tra ase mfe pii.

Ɛnyɛ bere nyinaa na yare a enni sabea te sɛ CLL a wobɛtra ase. Ebia wobɛfa akwan horow pii so a ɛbɛma wo ho atɔ wo na woasan anya bi bio. Wɔ kyinhyia biara mu no, ebia wobɛhaw wo ho wɔ nea ɛbɛba akyi no ho. Wo nnuruyɛfo te sɛnea ɛte sɛ wo ne yare a enni sabea te ase. Wɔn ani begye ho sɛ wobebua nsɛmmisa biara a ebia wowɔ na wɔaboa wo wɔ ɔkwan biara a wobetumi so. Enti, nsuro da sɛ wo ne wo duruyɛfo bɛkasa afa nneɛma a ɛhaw wo ho.

` Leukemia, CLL, mogya mu kokoram, sɛnkyerɛnne, ayaresa, lymphocytes, ahotɔ