So dade pii wɔ wo nipadua mu dodo? Momma yɛnka Hemochromatosis ho asɛm!

So ɛtɔ mmere bi a wote nka sɛ woabrɛ wɔ ɔkwan soronko so a ntease biara nnim? So wo nkwaa, titiriw wo nkotodwe ne wo nansoaa yɛ yaw, na wo honam ani yɛ fitaa anaa kɔbere kakra? Yɛtaa bu saa nneɛma yi animtiaa sɛ "ɔkwan a yɛfa so nyin ara kwa." Nanso eyinom betumi ayɛ tebea bi a dade dodow a ɛwɔ yɛn nipadua mu no kɔ soro wɔ ɔkwan a ɛyɛ hu so ho sɛnkyerɛnne. Wɔ aduruyɛ mu frɛ saa tebea yi Hemochromatosis . Eyi ne nea yɛreka ho asɛm nnɛ.

Sɛ yɛbɛka no tiawa a, dɛn ne Hemochromatosis?

Hemochromatosis yɛ tebea a ɛma wo nipadua boaboa dade pii ano dodo . Nnipa binom nso frɛ no " dade a ɛboro so ."

Mpɛn pii no, dade dodow a yehia fi aduan a yedi mu nkutoo na yɛn nipadua no twe. Nanso, wɔ nnipa a wɔwɔ hemochromatosis mu no, nipadua no twetwe dade pii sen sɛnea ehia. Ɔhaw no ne sɛ ɔkwan biara nni hɔ a wɔbɛfa so ayi dade a ɛboro so yi afi nipadua no mu.

Enti ɛhe na nipadua no de dade a ɛboro so yi sie? Wɔde asie wo nkwaa mu, ne akwaa a ɛho hia te sɛ wo mmerɛbo , koma , honam ani, pituitary gland, ne pancreas mu nso. Bere kɔ so no, saa dade a aboaboa ano yi fi ase sɛe saa akwaa ahorow no. Sɛ wɔansa saa akwaa yi a, ebetumi agyae adwumayɛ mpo.

Saa yare yi ahorow atitiriw abien na ɛwɔ hɔ.

Wobetumi akyekyɛ tebea yi mu titiriw ayɛ no ahorow abien.

1. Primary Hemochromatosis: Eyi ne nea abu so sen biara. Ɛyɛ awosu mu nneɛma. Sɛ yɛbɛka no tiawa a, sɛ wubenya saa yare yi a, ɛsɛ sɛ wunya awosu mu abɔde a asɛe no fi wo maame ne wo papa nyinaa hɔ. Sɛ wunya fi ɔwofo biako pɛ hɔ a, worennya yare no, nanso ebia woyɛ obi a ɔwɔ awosu mu abɔde no.

2. Secondary Hemochromatosis: Eyi ba esiane nneɛma afoforo nti. Sɛ nhwɛso no, saa tebea yi betumi aba obi a ɛsɛ sɛ wɔtaa ma mogya esiane tebea bi te sɛ mogya a ɛtɔ kɔ nipadua mu a emu yɛ den nti.

Dɛn na ɛde tebea yi ba?

Ma yɛnhwɛ nea enti a ɛte saa.

Nneɛma a efi awosu mu ba (Primary Hemochromatosis) .

Yɛn nipadua wɔ awosu mu abɔde bi a wɔfrɛ no `HFE`. Eyi na ɛhwɛ dade dodow a yɛtwe fi aduan a yedi mu no so. Nsakrae abien a ɛba saa `HFE` awosu mu abɔde yi mu, a ɛne `C282Y` ne `H63D`, na ɛde ayarefo dodow no ara a wonya hemochromatosis a wonya fi awo mu no ba.

Bio nso, nkwaadɔm mu nsakraeɛ a ɛba awosuo mu nkwaadɔm foforɔ te sɛ `HJV` ne `HAMP` nso tumi de saa yareɛ yi ba nnipa kakraa bi mu (bɛyɛ 10%-15%). Nnipa a saa awosu mu nkwaadɔm yi aka wɔn no taa nya yare no ho sɛnkyerɛnne wɔ wɔn mmofraase.

Ayaresa mu tebea afoforo na ɛde ba (Secondary Hemochromatosis) .

Mpɛn pii no, mogya a wɔtaa ma esiane tebea horow te sɛ mogya a ɛtɔ kɔ nipadua mu a emu yɛ den (te sɛ sickle cell anemia) anaa nnompe mu ntini a entumi nyɛ adwuma nti na ɛde saa su yi ba. Mogya mu nkwammoaa kɔkɔɔ a wɔde ma bere a wode mogya ma no, dade pii wɔ mu. Esiane sɛ nipadua no nni ɔkwan biara a ɛbɛfa so ayi dade yi afi hɔ nti, wofi ase boaboa ano.

Afei nso, sɛ nhwɛso no, mmerɛbo a ɛsɛe esiane mmerɛbo mu yare a srade wom ( cirrhosis ) anaasɛ hepatitis B anaa C a enni sabea nti, betumi ama dade aboaboa ano wɔ nipadua no mu.

Henanom na wɔwɔ asiane kɛse mu sɛ wobenya saa yare yi?

Ɛwom sɛ obiara betumi anya hemochromatosis de, nanso nnipa binom wɔ asiane kɛse mu.

So wowɔ saa sɛnkyerɛnne ahorow yi nso?

Nnipa a wɔwɔ hemochromatosis no mu bɛyɛ fã nhu sɛnkyerɛnne biara. Mpɛn pii no, mmarima nya yare no ho sɛnkyerɛnne bere a wɔadi fi mfe 30 kosi 50, bere a mmea taa nya yare no ho sɛnkyerɛnne bere a wɔadi mfe 50 anaa bere a wɔagyae brayɛ akyi.

Wobɛyɛ dɛn ahu eyi, Oduruyɛfo?

Esiane sɛ wotumi hu saa sɛnkyerɛnne ahorow yi wɔ nyarewa afoforo mu nti, ɛtɔ mmere bi a ebetumi ayɛ den sɛ wobehu. Wo duruyɛfo bebisa wo w’abusua aduruyɛ ho abakɔsɛm na ɔbɛyɛ wo nipadua mu nhwehwɛmu nso.

Nea ɛka ho no, wobetumi ayɛ nhwehwɛmu ahorow yi:

• Mogya mu nhwehwɛmu: Wɔyɛ nhwehwɛmu atitiriw abien wɔ ha.
• Transferrin Saturation: Eyi kyerɛ dade dodow a ɛkyekyere protein (transferrin) a ɛde dade kɔ mogya no mu.
• Serum Ferritin: Eyi kyerɛ protein (ferritin) dodow a ɛkora dade so wɔ mogya no mu.

Sɛ nhwehwɛmu ahorow yi kyerɛ sɛ dade dodow a ɛwɔ wo mu no dɔɔso a, ebia wo duruyɛfo no nso bɛyɛ awosu mu nhwehwɛmu de ahwɛ sɛ wowɔ awosu mu abɔde a ɛde hemochromatosis ba anaa.

• Berɛbo mu Nhwehwɛmu: Oduruyɛfo no yi ntini ketewaa bi fi mmerɛbo no mu na ɔde afiri a wɔde hwɛ nneɛma nketenkete hwehwɛ mu hwɛ sɛ ebia mmerɛbo no asɛe anaa.

• MRI scan: Eyi betumi atwa w’akwaa no ho mfonini a emu da hɔ na woahu sɛ ebia dade a ɛwɔ mu anaa.

Dɛn ne ayaresa ahorow no?

Sɛ wowɔ Primary Hemochromatosis a, ayaresa no yɛ mmerɛw yiye. Nea ɛka ho ne sɛ wubeyi mogya afi wo nipadua mu wɔ nhyehyɛe pɔtee bi mu. Wɔfrɛ eyi Phlebotomy.

Phlebotomy a wɔde yɛ adwuma

Eyi te sɛ mogya a wɔde ma no. Oduruyɛfo anaa ɔyarehwɛfo a wɔatete no de ade bi hyɛ ntini bi a ɛwɔ wo nsa mu mu na ɔtwe mogya kɔ mogya kotoku mu.

• Ayaresa a edi kan: Mfiase no, ebehia sɛ wokɔ ayaresabea pɛnkoro anaa mprenu dapɛn biara kɔtwe mogya kosi sɛ wo dade dodow asan ayɛ sɛnea na ɛte kan no. Eyi betumi agye asram pii anaa afe biako.
• Ayaresa a wɔde siesie: Sɛ dade dodow san kɔ sɛnea na ɛte kan no a, wɔtew mpɛn dodow a wɔde mogya ma no so, na mpɛn pii no ɛkɔ mprenu kosi anan afe biara.

Nnuru a wɔde sa yare (Chelation Therapy) .

Sɛ wowɔ hemochromatosis a ɛto so abien, anaasɛ wo ntini no mu nyɛ den sɛnea ɛbɛyɛ a ɛbɛtwe mogya a, wo duruyɛfo betumi akyerɛw wo aduru bi a wɔfrɛ no `Chelation Therapy.` Wɔ eyi mu no, wɔma wo aduru bi a ɛboa ma wo nipadua no yi dade a ɛboro so no fi hɔ denam wo nsu ne wo nsu mu.

So wobetumi adi tebea yi ho dwuma wɔ fie?

Mpɛn pii no, ɛho nhia sɛ obi a wɔreyɛ no phlebotomy ayaresa no yɛ nsakrae kɛse biara wɔ n’aduan mu, efisɛ ayaresa no ankasa hwɛ wɔn dade dodow so. Nanso, wubetumi ayɛ nea edidi so yi na ama asiane a ɛwɔ hɔ sɛ wubenya nsɛnnennen no so atew:

• Kwati nsa koraa. Nsã sɛe mmerɛbo no, na ɛma ɛyɛ hu kɛse wɔ saa yare yi ho.
• Kwati sɛ wubedi mpataa anaa akutu a wɔannoa. Mmoawa a ɛwɔ eyinom mu no betumi de nyarewa a emu yɛ den aba nnipa a dade dɔɔso wom so.
• Kwati sɛ wobɛnom vitamin C a wɔde ma. Nanso, ɔhaw biara nni nnuaba ne nhabannuru a vitamin C wom a wobedi mu.
• Kwati sɛ wobɛnom nnuru a wɔde dade ayɛ anaa vitamin pii a iron wom.
• Kwati anɔpaduan a wɔde dade ahyɛ mu ma.