So dade ahyɛ wo nipadua mu ma dodo? Momma yensua hemochromatosis ho ade.

So wotaa te ɔbrɛ nka na wo nkwaa mu yɛ wo yaw? Ɛtɔ mmere bi a yesusuw sɛ eyinom yɛ ade a ɛfata na yebu yɛn ani gu so. Nanso saa nneɛma yi nso betumi ayɛ dade pii a ɛwɔ yɛn nipadua mu ho sɛnkyerɛnne. Ɛnnɛ yɛreka tebea a ɛte saa biako ho asɛm, "Hemochromatosis". Ɛwom sɛ eyi yɛ din a wonnim kakra de, nanso ɛho hia yiye sɛ wubehu ho asɛm.

Sɛ yɛbɛka no tiawa a, dɛn ne hemochromatosis?

Hemochromatosis yɛ tebea a ɛma wo nipadua boaboa dade pii ano dodo. Nnipa binom nso frɛ no "dade a ɛboro so." Mpɛn pii no, dade dodow a yɛn nipadua hia fi nnuan a yedi mu nkutoo na yɛn dwensɔtwaa twe. Nanso wɔ nnipa a wɔwɔ hemochromatosis mu no, nipadua no twetwe dade pii sen sɛnea ehia. Ɔhaw no ne sɛ ɔkwan biara nni hɔ a wɔbɛfa so ayi dade a ɛboro so yi afi hɔ. Enti nipadua no de dade a ɛboro so yi sie wo nkwaa ne akwaa a ɛho hia te sɛ mmerɛbo, koma, ne dwensɔtwaa mu.

Saa tebea yi ahorow atitiriw abien na ɛwɔ hɔ.

Wobetumi akyekyɛ tebea yi mu ayɛ no ahorow atitiriw abien. 1. Primary Hemochromatosis: Eyi yɛ tebea a wonya fi awo mu. Ɛne sɛ, ɛnam abusua no mufo so nam awosu mu nkwaadɔm so. Sɛ yɛbɛka no pɛpɛɛpɛ a, sɛ wubenya saa yare yi a, ɛsɛ sɛ wunya awosu mu abɔde a asɛe no fi wo maame ne wo papa nyinaa hɔ. 2. Secondary Hemochromatosis: Eyi ba esiane nneɛma afoforo nti. Sɛ nhwɛso no, saa tebea yi betumi aba nnipa a wɔwɔ ayaresa tebea bi a ɛhwehwɛ sɛ wɔtaa ma mogya (sɛ nhwɛso no, thalassemia) anaa nnipa a wɔwɔ mmerɛbo mu nyarewa afoforo mu.

Dɛn ne nneɛma a ɛde hemochromatosis ba?

Nneɛma a efi awosu mu ba

HFE awosu mu abɔde no na ɛhwɛ dade dodow a yɛn nipadua no twetwe fi aduan mu no so. Nsakrae abien a ɛba HFE awosu mu abɔde mu, C282Y ne H63D, na ɛde awosu mu mogya mu nkwammoaa dodow no ara ba. Awosu mu nkwaadɔm afoforo nso betumi de nsɛm kakraa bi aba (bɛyɛ 10%-15%). Wɔfrɛ eyinom sɛ non-HFE hemochromatosis. Sɛ nkwaadɔm mu nsakrae ba awosu mu nkwaadɔm te sɛ HJV anaa HAMP mu a, mpɛn pii no, sɛnkyerɛnne ahorow no da adi wɔ mmofraase. Ɛtɔ mmere bi a, mmerɛbo a ɛsɛe ne mmerɛbo mu yare betumi aba ntɛm ara wɔ abofra kumaa mu.Ɛda adi sɛ tebea no bɛsɔre.

Nneɛma afoforo a ɛde ba (Secondary Causes) .

Mpɛn pii no, saa ɔkwan yi ba bere a obi wɔ tebea bi te sɛ mogya a ɛtɔ kɔ nipadua mu a emu yɛ den na ohia sɛ wɔtaa ma no mogya no. Nea enti a ɛte saa ne sɛ, mogya mu nkwammoaa kɔkɔɔ a wofi abɔnten de ma wɔn no, dade pii wɔ mu. Esiane sɛ nipadua no nni ɔkwan biara a ɛbɛfa so ayi saa dade yi afi hɔ nti, efi ase boaboa ano. Dade a ɛboaboa ano nso betumi akɔ soro bere a nyarewa te sɛ mmerɛbo mu yare anaa mmerɛbo mu yare a enni sabea B anaa C asɛe no.

Hena na ɔwɔ asiane kɛse ma eyi?

Sɛ wowɔ nneɛma a edidi so yi a, asiane kɛse wom sɛ wubenya hemochromatosis. Momma yɛnhwɛ pon bi na yɛate eyi ase yiye.

Dɛn ne hemochromatosis ho sɛnkyerɛnne ahorow?

Nnipa a wɔwɔ hemochromatosis no mu bɛyɛ fã nhu sɛnkyerɛnne biara. Wɔ mmarima fam no, mpɛn pii no, sɛnkyerɛnne ahorow no fi ase da adi bere a wɔadi mfe 30 kosi 50. Wɔ mmea fam no, mpɛn pii no, sɛnkyerɛnne ahorow no da adi wɔ mfe 50 akyi, anaasɛ bere a wɔagyae brayɛ akyi. Nsɛnkyerɛnne atitiriw no bi ni:

• Nkwaa mu yaw , titiriw wɔ nkwaa ne nkotodwe mu.
• Ɔbrɛ a enni sabea a ntease biara nnim.
• Mu duru a ɛso tew a ntease biara nnim.
• Wora a ɛdan kɔbere anaa fitaa .
• Yafunu mu yaw .
• Ɔbarima ne ɔbea nna ho akɔnnɔ a ɛso tew .
• Nipadua mu nhwi a ɛtɔ.
• Nsakrae a ɛba koma a ɛbɔ mu (Heart flutter).
• Sɛ obi kae ade a sum kabii a, ɛte sɛ nea ɛyɛ basaa kakra, te sɛ amemene a sum ayɛ no ma.

Ɛtɔ da bi a, yareɛ no nna saa nsɛnkyerɛnneɛ yi adi, na mmom ɛda adi sɛ nsɛnnennen foforɔ. Nhwɛsoɔ:

• mmerɛbo mu haw ahorow, titiriw mmerɛbo mu yare a ɛma obi ho kyere no
• Asikreyare a ɛma obi nya asikreyare
• Koma a ɛbɔ a ɛnyɛ ne kwan so
• Ntini mu yare
• Ɔbarima ne ɔbea nna a ɛnyɛ adwuma yiye

Wobɛyɛ dɛn ahu eyi, Oduruyɛfo?

Esiane sɛ wotumi hu saa sɛnkyerɛnne ahorow yi wɔ nyarewa afoforo mu nti, ɛtɔ mmere bi a, sɛnea wohu yare no betumi ayɛ den kakra. Nanso sɛ wowɔ yare no ho sɛnkyerɛnne, nneɛma a ɛde asiane ba, anaa abusua muni bi wɔ yare no a, wo duruyɛfo bɛhwɛ sɛ ebia ɛwɔ hɔ anaa. Akwan titiriw a wɔfa so hu yare no bi ni:

• Wo ne w’abusua aduruyɛ ho abakɔsɛm a wubebisa: Oduruyɛfo no bebisa sɛ ebia w’abusua mu obi wɔ saa yare yi, mmerɛbo mu yare, anaa ntini mu yare yi anaa.
• Nipadua mu nhwehwɛmu: Wɔbɛhwehwɛ wo nipadua mu.
• Mogya mu nhwehwɛmu: Wɔyɛ nhwehwɛmu atitiriw abien.

1. Transferrin saturation: Eyi kyerɛ sɛnea dade dodow a ɛkyekyere transferrin, protein a ɛde dade kɔ mogya no mu no. 2. 2. .Serum ferritin: Eyi kyerɛ sɛnea ferritin, protein a ɛkora dade so wɔ nipadua no mu no dodow. Sɛ nhwehwɛmu ahorow yi kyerɛ sɛ dade dɔɔso a, ebia wo duruyɛfo de wo bɛkɔ akɔyɛ awosu mu nhwehwɛmu de ahu sɛ ebia wowɔ awosu mu abɔde a ɛde hemochromatosis ba anaa.

• Berɛbo mu nhwehwɛmu: Wɔfa mmerɛbo no fã ketewaa bi na wɔde afiri a wɔde hwɛ nneɛma nketenkete hwehwɛ mu hwɛ sɛ ebia mmerɛbo no asɛe anaa.
• MRI scan: Ɛde magnet ne radio asorɔkye di dwuma de yɛ w’akwaa ho mfonini pefee.

Dɛn ne ayaresa ahorow no?

Sɛ wowɔ hemochromatosis a wonya fi awo mu a, ayaresa titiriw ne phlebotomy . Sɛ yɛbɛka no tiawa a, eyi ne mogya a woyi fi wo nipadua mu bere ne bere mu . Ɛte sɛ sɛnea yɛde mogya ma wɔ Sri Lanka no. Oduruyɛfo anaa ɔyarehwɛfo a wɔatete no de ade bi hyɛ ntini bi a ɛwɔ wo nsa mu mu na oyi mogya dodow bi fi mu. Eyi botae titiriw ne sɛ ɛbɛma dade dodow a ɛwɔ wo mogya mu no asan ayɛ nea ɛfata. Eyi si wɔ afã abien:

• Ayaresa a edi kan: Ɛho behia sɛ wokɔ ayaresabea anaa ayaresabea pɛnkoro anaa mprenu dapɛn biara kɔtwe mogya kosi sɛ wo dade dodow bɛsan ayɛ sɛnea ɛsɛ. Eyi betumi agye afe biako anaa nea ɛboro saa.
• Ayaresa a wɔde siesie: Sɛ dade dodow san ba sɛnea ɛsɛ a, mpɛn dodow a wɔde mogya ma no so tew. Wɔtaa yɛ eyi mprenu kosi anan afe biara.

Sɛ wowɔ hemochromatosis a ɛto so abien, anaasɛ wo ntini no mu nyɛ den sɛnea ɛbɛyɛ a ebetumi ayi mogya no a, ebia wo duruyɛfo bɛkamfo aduru bi a wɔfrɛ no chelation therapy akyerɛ wo . Nea ɛka eyi ho ne sɛ wɔbɛma wo nnuru a ɛboa ma wo nipadua no fa wo nsu ne wo nsu mu yi dade a ɛboro so no fi hɔ.

Nsakrae bɛn na wubetumi ayɛ wɔ fie ne w’asetra kwan mu?

Sɛ wɔreyɛ wo phlebotomy a, mpɛn pii no ɛho nhia sɛ wudi aduan a ɛyɛ katee akyi efisɛ ɛboa ma wohwɛ wo dade dodow so. Nanso, wubetumi ayɛ nea edidi so yi na ama asiane a ɛwɔ hɔ sɛ wubenya nsɛnnennen no so atew:

• Kwati nsa koraa. Nsã betumi ama mmerɛbo a ɛsɛe no ayɛ kɛse.
• Kwati sɛ wubedi mpataa anaa akutu a wɔannoa. Ebia mmoawa a wotumi de nyarewa ba nnipa a dade dɔɔso wom mu.
• Kwati sɛ wobɛnom vitamin C a wɔde ma. Nanso, ɔhaw biara nni abɔde mu nnuan a vitamin C wom (e.g. oranges, tangerines) a wobedi mu.
• Kwati sɛ wobɛnom nnuru a wɔde ma iron anaa multivitamins a iron wom.
• Kwati anɔpaduan mu aburow a wɔde dade (a wɔahyɛ no den) aka ho.
• Tew nnuan a dade wom a wudi so (sɛ nhwɛso no, oysters, duck, spinach). Bisa wo duruyɛfo no eyi ho asɛm.Tie na hwehwɛ pii.

Nkrasɛm a Wɔde Kɔ Fie

• Hemochromatosis yɛ tebea a ɛma dade pii boaboa ano wɔ nipadua no mu. Ɛyɛ awosu mu tebea titiriw a wɔde fa awo ntoatoaso ahorow mu.
• Nsɛnkyerɛnne no betumi ayɛ ɔbrɛ, nkwaa mu yaw, ne honam ani kɔla a ɛsakra. Ebia nnipa binom rennya yare no ho sɛnkyerɛnne biara koraa.
• Sɛ wowɔ sɛnkyerɛnne bi anaa obi a ɔwɔ w’abusua mu wɔ saa yare yi a, kɔ wo duruyɛfo nkyɛn ntɛm ara kɔhwehwɛ afotu.
• Sɛ wohu yare no ntɛm na wɔsa (Phlebotomy) a, ebetumi ahyɛ dade dodow a ɛwɔ nipadua no mu no so na asiw akwaa a ɛsɛe no ano.
• Eyi nyɛ tebea a ɛsɛ sɛ wosuro. Sɛ wonya ayaresa ne afotu a ɛfata a, wubetumi abɔ bra a ɛfata na apɔwmuden wom.

Hemochromatosis, Dade a ɛboro so, Mmɛn mu yare, Nkwaa mu yaw, Ntini mu yare