Nea ɛsɛ sɛ wuhu fa kokoram aduru a wɔfrɛ no Selpercatinib (Retevmo) ho .

Kokoram ayaresa a wubefi ase ama wo anaa wo dɔfo bi betumi ayɛ bere a ɛyɛ den na ɛyɛ basaa. Ebia wowɔ nsɛmmisa fa nnuru a wo duruyɛfo de rema wo, ne din, ne nea efi mu ba no ho. Enti ɛnnɛ yɛbɛka kokoram aduru titiriw biako a ɛte saa, Selpercatinib , ho asɛm. Ebia wunim no denam brand din Retevmo so. Momma yɛnka aduru yi, nea ɛyɛ, ne nea ɛsɛ sɛ yɛma yɛn ani da hɔ ho asɛm wɔ ɔkwan a ɛnyɛ den na ɛnyɛ den sɛ yɛbɛte ase so.

Dɛn na ɛba wɔ aduru yi ho ankasa?

Sɛ yɛbɛka no tiawa a, Selpercatinib nte sɛ nnuru a wɔde sa yare a wɔde di dwuma wɔ amanne kwan so. Ɛyɛ adwuma te sɛ "ayaresa a wɔde asi wɔn ani so." Protein ahorow bi a ɛwɔ yɛn nipadua mu no de nsɛnkyerɛnne kɔma kokoram nkwammoaa sɛ “wonyin pii, ntrɛw ntɛmntɛm.” Fa no sɛ ɛyɛ nsakrae a ɛma kokoram nkwammoaa nyin. Nea Selpercatinib yɛ ne sɛ ɛma protein a ɛde sɛnkyerɛnne a ɛnteɛ ba no yɛ adwuma . Ɛte sɛ nea woadum saa switch no. Afei wɔhwɛ sɛnea kokoram nkwammoaa nyin na ɛtrɛw wɔ nipadua no nyinaa mu no so.

Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi ase anom nnuru

Ansa na wubefi saa ayaresa yi ase no, ɛsɛ sɛ wo duruyɛfo nya w’akwahosan ho mfonini a edi mũ. Hwɛ hu sɛ wobɛka tebea horow a edidi so yi mu biara ho asɛm akyerɛ wɔn, titiriw sɛ wowɔ bi a:

Ɔkwan bɛn so na ɛsɛ sɛ mede saa aduru yi di dwuma?

Eyi yɛ capsule a wode w’ano nom. Ɛho hia yiye sɛ wobɛnom bere koro mu da biara , sɛnea wo duruyɛfo akyerɛ wo no pɛpɛɛpɛ.

• Fa nsu mene capsule no nyinaa . Mmu, nsɛe, anaa nwe capsule no.
• Wubetumi de eyi aka aduan ho anaasɛ wunhia. Nanso, sɛ wote nka sɛ wo yafunu ayɛ wo yaw kakra a, ɛbɛyɛ papa sɛ wode bɛka adidi ho.
• Kɔ so sa yare no kosi sɛ wo duruyɛfo bɛka akyerɛ wo sɛ gyae.
• Nea ɛho hia yiye: Kwati sɛ wobɛnom bobe nsu koraa bere a worenom aduru yi no.

Na sɛ mepa nnuru dodow bi nso ɛ?

Sɛ wopa dose bi a, fa no bere a woakae ara pɛ. Nanso, sɛ ɛboro nnɔnhwerew 18 boro wo dodow a edi hɔ no so (a ɛkyerɛ sɛ ennu nnɔnhwerew 6 kosi wo dodow a edi hɔ no so) a, twa dodow a woayera no so na fa wo dodow a edi hɔ no wɔ bere a wotaa de di dwuma no mu. Mfa nnuru abien prɛko pɛ da mfa nsiesie dodow a woayera no.

Na sɛ menom nnuru pii nso ɛ?

Sɛ wususuw sɛ woanom nnuru pii sen sɛnea wususuw a, mma wo ho nnyɛ wo hu. Kɔ ayaresabea Emergency Department (ETU) a ɛbɛn wo ntɛm ara. Anaasɛ, frɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea hɔ no na woanya afotu.

Nneɛma afoforo a ebia ɛne aduru yi bedi nkitaho

Nnuru binom betumi ne Selpercatinib adi nkitaho, asakra sɛnea ɛyɛ adwuma anaasɛ ɛma nea efi mu ba no yɛ kɛse.

Bio nso, nnuru afoforo, nhabannuru, ne nnuan betumi ne saa aduru yi adi nkitaho. Enti, ɛho hia sɛ woka nnuru a worenom nyinaa (a vitamin, nhabannuru, ne nnuru a wɔde ka ho) kyerɛ wo duruyɛfo.

• Mogya mmoroso nnuru bi (diltiazem anaa verapamil) .
• Nnuru bi a wɔde ko tia HIV anaa Hepatitis
• Nnuru a wɔde sa fungal yare (itraconazole, posaconazole) .
• Grapefruit nsu a wɔde yɛ
• Nnuru afoforo a ɛsakra koma bɔ
• Repaglinide a wɔde sa asikreyare
• Rifampin a wɔde sa nsamanwaw
• Nneɛma a wɔde nhabannuru yɛ te sɛ St. John’s Wort
• Nnuru a ɛtew yafunu mu acid so (te sɛ cimetidine, famotidine, ranitidine, lansoprazole, omeprazole) .

Nneɛma a ɛsɛ sɛ wohwɛ yiye wɔ ho titiriw bere a worenom aduru no

• Sɛ wote nka sɛ wo ho nyɛ wo den: Ɛyɛ ade a ɛfata sɛ wobɛte nka sɛ wo ho nyɛ wo den kakra anaasɛ wo ho nyɛ wo den bere a worenom aduru yi. Nea enti a ɛte saa ne sɛ saa aduru yi ka kokoram nkwammoaa ne nkwammoaa a wɔwɔ apɔwmuden nyinaa kodu baabi. Nanso, nnyae ayaresa no kosi sɛ wo duruyɛfo bɛka akyerɛ wo. Ka ɔhaw biara a wubenya ho asɛm kyerɛ wo duruyɛfo.
• Oprehyɛn: Sɛ worekɔyɛ oprehyɛn (sɛ ɛyɛ biribi ketewaa bi te sɛ sẽ a wobeyi mpo a) ka kyerɛ wo duruyɛfo. Ebia saa aduru yi bɛkyɛ akuru no yare. Enti, mpɛn pii no, anyɛ yiye koraa no, ebehia sɛ wugyae aduru no nom nnafua 7 ansa na wɔayɛ oprehyɛn no na woasan afi ase bio wɔ oprehyɛn no akyi adapɛn 2, bere a kuru no ayɛ yiye koraa no.
• Nyinsɛn ne nufu a wɔde ma: Wɔ mmea fam no: Kwati sɛ wubenyinsɛn bere a worenom aduru yi ne dapɛn biako bere a woagyae aduru no akyi. Eyi nti na ɛho hia sɛ wɔde awo ano aduru a wotumi de ho to so di dwuma no. Ɛsɛ sɛ woyɛ nyinsɛn mu nhwehwɛmu ansa na woafi aduru no ase de ahwɛ ahu sɛ wunnyinsɛn. Afei nso, kwati sɛ wobɛma nufu wɔ saa bere yi mu ne dapɛn biako bere a woagyae aduru no akyi. Wɔ mmarima fam: Fa kɔndɔm di dwuma bere nyinaa sɛ wo ne ɔbea bi a obetumi anyinsɛn bere a worenom aduru yi ne dapɛn biako bere a woagyae aduru no akyi a. Sɛ wo hokafo nyinsɛn a, ebetumi apira akokoaa a ɔwɔ awotwaa mu no.
• Awo: Ebia aduru yi bɛka sɛnea wubetumi awo mma. Sɛ wowɔ eyi ho haw bi a, wo ne wo duruyɛfo nkasa.
• Mogya mmoroso:Hwɛ wo mogya mmoroso bere nyinaa sɛnea wo duruyɛfo ka kyerɛ wo no. Hu nea ɛsɛ sɛ ɛyɛ ne bere a ɛsɛ sɛ wofrɛ wo duruyɛfo.

Nsunsuanso bɔne bɛn na ebia menya?

Te sɛ aduru biara no, Selpercatinib betumi de ɔhaw ahorow aba. Ebi yɛ aniberesɛm, bere a afoforo nso abu so.

Saa nsɛm a wɔahyehyɛ yi nka nsunsuanso bɔne a ebetumi aba nyinaa ho. Sɛ wuhyia biribi a ɛyɛ soronko a, wo ne wo duruyɛfo nka ho asɛm.