Sɛ oduruyɛfo ka kyerɛ wo anaa wo dɔfo bi sɛ wowɔ " nufu mu kokoram" a, ɛyɛ ade a ɛfata sɛ wobɛte nka sɛ wo wiase nyinaa aba ahwe ase. Nea ɛka ehu ne dadwen a ɛba w’adwenem ho no, wowɔ nsɛmmisa apem nso a ɛfa ayaresa ne nnuru a oduruyɛfo no kyerɛw ma wo no ho. "So saa aduru yi ye ma nipadua no?", "So ɛde nsunsuanso bɔne bɛba ?", "So eyi bɛyɛ adwuma ampa?" Ebia nneɛma a ɛtete saa retu mmirika wɔ wo tirim. Saa na yɛrebɛka Tamoxifen, aduru a ɛho hia yiye a wɔde di dwuma kɛse wɔ nufu mu kokoram ayaresa mu , ho asɛm wɔ ɔkwan a ɛyɛ mmerɛw na ɛyɛ adamfofa su so nnɛ.
Sɛ yɛbɛka no tiawa a, dɛn ne Tamoxifen?
Tamoxifen yɛ aduru a wɔde sa nufu mu kokoram a ɛwɔ hormone receptor-positive . Ɛba sɛ aduru (Nolvadex®) anaa nsu (Soltamox®).
Afei ebia woresusuw ho sɛ, "Dɛn ne kokoram a egyina hormone so yi?" Ɛyɛ mmerɛw yiye. Kokoram nkwammoaa bi a ɛwɔ yɛn nipadua mu te sɛ afifide ketewaa bi. Sɛnea afifide hia nsu ne aduannuru na ama anyin na anyin no, saa ara na kokoram nkwammoaa yi hia nkwaadɔm a wɔfrɛ no estrogen anaa progesterone na ama anyin na atrɛw. Ɛno ne nea yɛfrɛ no ‘kokoram a egyina hormone so.’
Nea aduru tamoxifen yɛ ne sɛ esiw estrogen hormone a kokoram nkwammoaa hia no dwumadi ano. Ɛte sɛ nea wodum nsu tap no ama afifide bi. Afei kokoram nkwammoaa no nnya nkrasɛm a wohia na ama wɔanyin no.
Afei nso, ɛtɔ mmere bi a nnuruyɛfo kamfo saa aduru yi kyerɛ sɛ wɔmfa nsiw kokoram ano wɔ nnipa a asiane kɛse wom sɛ wobenya nufu mu kokoram (sɛ nhwɛso no, sɛ obi a ɔwɔ abusua no mu anya kokoram a ).
Henanom na wɔkamfo aduru yi kyerɛ?
Wɔmfa tamoxifen mma wɔn a wɔwɔ nufu mu kokoram nyinaa. Wo duruyɛfo no besusuw nneɛma pii ho, a w’ayaresa ho abakɔsɛm ne kokoram ko a wowɔ ka ho, de asi gyinae sɛ ebia aduru yi fata wo anaa. Wɔde di dwuma titiriw wɔ nsɛm a edidi so yi mu:
- Wɔn a wɔwɔ abusua abakɔsɛm a ɛfa kokoram anaa BRCA awosu mu nkwaadɔm mu nsakrae hoSɛ́ adeyɛ a wɔde besiw kokoram ano wɔ wɔn a asiane kɛse wom sɛ wobenya nufu mu kokoram esiane nneɛma te sɛ:
- Siw kokoram a ɛbɛsan aba obi a wanya nufu mu kokoram dedaw na wɔayɛ no ayaresa te sɛ oprehyɛn , nnuru a wɔde sa yare anaa mframa a wɔde sa yare no ano .
- Siw kokoram ano wɔ nufu foforo a ɛwɔ apɔwmuden mu ma obi a ɔwɔ kokoram wɔ nufu biako mu.
- Wɔ obi a ɔwɔ kokoram a edi kan koraa, te sɛ DCIS (ductal carcinoma in situ) fam no, siw ano sɛ ɛntrɛw nkɔ akyiri na ɛnyɛ kokoram a emu yɛ den kɛse.
Ade a ɛho hia sen biara ne sɛ ɛsɛ sɛ wo duruyɛfo na osi gyinae sɛ ebia wobɛnom aduru yi anaasɛ worennom, ne bere tenten a wode bɛnom no. Enti nsuro sɛ wo ne wo duruyɛfo besusuw nsɛmmisa biara a wowɔ wɔ eyi ho.
Mfaso atitiriw bɛn na ɛwɔ Tamoxifen so?
Tamoxifen yɛ aduru a aboa ma wɔagye mmea ɔpepem pii nkwa wɔ wiase nyinaa mfe du du pii ni. Mfaso a efi eyi so no nyɛ ade ketewaa bi.
- Ɛtew kokoram a ɛsan ba bio so: Saa aduru yi betumi atew asiane a ɛwɔ hɔ sɛ kokoram bɛsan aba bere a wɔasa no akyi no so 30% kosi 50% .
- Ɛbɔ nufu foforo no ho ban: Wɔ obi a wanya kokoram wɔ nufu biako mu fam no, asiane a ɛwɔ hɔ sɛ obenya kokoram wɔ nufu foforo no mu no so tew bɛyɛ 50% .
- Siw kokoram ano: Wɔ obi a ɔwɔ asiane kɛse fam no, asiane a ɛwɔ hɔ sɛ obenya kokoram wɔ nea edi kan no mu no betumi atew bɛyɛ 40% .
- Ɛhyɛ nnompe den: Saa aduru yi boa ma wosiw nnompe mu yare , yare a ɛma nnompe yɛ mmerɛw a ɛba titiriw bere a obi agyae brayɛ no ano.
- Ɛtew srade a ɛwɔ nipadua no mu so: Tamoxifen nso tumi tew srade bɔne a ɛwɔ nipadua no mu no so.
Dɛn ne nsunsuanso bɔne a ebetumi afi Tamoxifen a wɔnom mu aba?
Te sɛ aduru biara no, Tamoxifen betumi de nsunsuanso bɔne bi aba. Nanso eyi nkyerɛ sɛ wubenya ne nyinaa mu osuahu. Ebia nnipa binom nte nka koraa. Ebia afoforo nso behyia biako anaa abien. Sɛ wudi kan hu saa nneɛma yi a, ɛbɛboa wo ma woagyina ano.
Momma yɛnkyekyɛ saa nsunsuanso bɔne yi mu abien.
| Nsunsuanso bɔne no su | Nkyerɛmu |
|---|---|
| Nneɛma bɔne a ɛtaa ba, a ɛnyɛ aniberesɛm pii | |
| Nsɛnkyerɛnne a ɛkyerɛ sɛ obi agyae brayɛ | Ɔhyew a ɛyɛ hyew, fifiri a ɛba anadwo, ne ɔbea awotwaa mu a ɛyɛ kusuu yɛ ɔhaw atitiriw a nnipa pii nya no bi. |
| Nsakrae a ɛba ɔsram biara brayɛ mu | Ebia brayɛ no bɛyɛ nea ɛnkɔ so daa anaasɛ ebegyae koraa. |
| Mu duru a ɛkɔ soro anaasɛ ɛho ahonhon | Ebia nnipa binom mu duru bɛkɔ soro kakra. Ebia afoforo nso bɛhonhon (edema) te sɛ nea nsu ahyɛ wɔn nipadua ma. |
| Nneɛma nketenkete afoforo a ɛhaw adwene | Ebia nsu a efi ɔbea no awotwaa mu, akisikuru, honam ani akisikuru, ɔbrɛ, tiyɛ, nan a ɛho ahonhon, ne ɔbarima ne ɔbea nna a ɛnyɛ den betumi aba. |
| Asiane ahorow a ɛntaa nsi nanso anibere wom | |
| Mogya a ɛtwetwe | Asiane ketewaa bi wɔ hɔ sɛ obi benya tebea horow te sɛ mogya a ɛbɛtɔ wɔ nan no ntini mu (deep vein thrombosis - DVT) anaasɛ ɔyare a ɛma obi hwe ase. |
| Awotwaa mu kokoram | Tamoxifen ma asiane a ɛwɔ hɔ sɛ obi benya awotwaa mu kokoram a ɛyɛ awotwaa no mu nneɛma no yɛ kɛse kakra. Eyi nti na ɛsɛ sɛ woka kyerɛ wo duruyɛfo ntɛm ara sɛ wunya mogya biara a ɛyɛ soronko wɔ awotwaa mu a. |
| Aniwa ho haw ahorow | Asiane a ɛwɔ hɔ sɛ obi benya atiridiinini no betumi ayɛ kɛse kakra. |
Ɛho hia sɛ wokae sɛ saa nsunsuanso bɔne a anibere wom yi ho yɛ na koraa , nanso nyansa wom sɛ wubehu na sɛ sɛnkyerɛnne a ɛtete saa ba a, wobɛbɔ wo duruyɛfo amanneɛ ntɛm ara.
Bere bɛn na ɛsɛ sɛ wofrɛ oduruyɛfo no ntɛm ara?
Sɛ worenom Tamoxifen na wohu sɛnkyerɛnne a edidi so yi mu biara a, ɛsɛ sɛ wobɔ wo duruyɛfo amanneɛ ntɛm ara anaasɛ wokɔ ayaresabea a ɛbɛn wo no Dwumadibea a Ɛhwɛ Ntɛmntɛm (ETU) nkyɛn .
- Sɛ wo koko yɛ wo yaw anaasɛ ɛyɛ den sɛ wobɛhome a .
- Sɛ wo nya atiridii a .
- Sɛ wowɔ akisikuru ho sɛnkyerɛnne - sɛ nhwɛso no, kasa a ɛyɛ mmerɛw, aniwa a ɛyɛ mmerɛw, anaasɛ nipadua no fã biako (basa, nan, anaa anim) a ɛyɛ mmerɛw mpofirim.
- Sɛ wo nan, wo nansoaa, anaa wo nan ho ahonhon mpofirim (titiriw wo nan biako pɛ).
- Sɛ wuntumi nnyae ɔfe a .
- Sɛ mogya a ɛba wo awotwaa mu a ɛyɛ soronko a .
Nsɛmmisa afoforo bi a wɔtaa bisa fa Tamoxifen ho
So Tamoxifen yɛ nnuru a wɔde sa yare?
Dabi, ɛha na nnipa pii adwene tu fra. Tamoxifen yɛ aduru a wɔde sa yare a ɛma nipadua no yɛ adwuma . Ɛka nnuru bi a wɔfrɛ no Selective Estrogen Receptor Modulators (SERMs) ho . Nnuru a wɔde sa yare yɛ aduru a ekum nkwammoaa a ɛpaapae ntɛmntɛm (kokoram nkwammoaa ne nkwammoaa a ɛte apɔw nso). Nanso Tamoxifen yɛ adwuma wɔ ɔkwan foforo so, wɔ hormone dodow mu.
So asiane biara nni ho sɛ wobɛnom Tamoxifen bere a wonyinsɛn?
Ɛnyɛ saa koraa. Sɛ wunyinsɛn bere a worenom tamoxifen a ebetumi ama obi anya awo mu dɛmdi a emu yɛ den . Enti sɛ worenom aduru yi a, ɛsɛ sɛ wokwati sɛ wubenyinsɛn . Hormone awo ano aduru (te sɛ awo ano aduru) mfata saa bere yi, enti kasa kyerɛ wo duruyɛfo mfa ɔkwan a ɛnyɛ hormone awo ano aduru (te sɛ kɔndɔm anaa IUD) a wode bedi dwuma ho. Ɛho hia sɛ wode awo ano aduru di dwuma anyɛ yiye koraa no asram abien bere a woagyae aduru no akyi .
Nnuan ne anonne bɛn na ɛsɛ sɛ wokwati bere a worenom Tamoxifen no?
Aane. Nnuan ne anonne bi betumi atew Tamoxifen a etu mpɔn no so. Enti, ɛbɛyɛ papa sɛ wobɛkwati eyinom:
- Borɔdɔma a wɔfrɛ no grapefruit
- Tangerines a wɔde yɛ nneɛma
- Nsã a ɛyɛ ɔkwan biara so
So nsunsuanso bɔne ba bere a wɔafi ase anom aduru no akyi pɛɛ?
Eyi gu ahorow wɔ onipa biara mu. Ebia nnipa binom befi ase ahu nsakrae nketenkete fi da a wɔnom aduru a edi kan no. Ebia afoforo nso renhu biribiara asram pii.
Bere tenten ahe na aduru no tra nipadua no mu bere a wɔagyae no?
Tamoxifen kɔ so yɛ adwuma wɔ nipadua no mu bɛyɛ adapɛn abien bere a woanom aduru a etwa to no akyi, nanso ebetumi adi bɛyɛ asram abiɛsa ansa na afi wo nipadua mu koraa.
Nkrasɛm a Wɔde Kɔ Fie
- Tamoxifen yɛ hormone aduru a etu mpɔn kɛse a wɔde sa nufu mu kokoram a egyina hormone so.
- Saa aduru yi brɛ asiane a ɛwɔ hɔ sɛ kokoram bɛsan aba bio na enyin foforo no ase kɛse.
- Mma ɛnhaw wo wɔ nsunsuanso bɔne a efi nnuru a wobɛnom mu ba no ho. Wobetumi adi emu dodow no ara ho dwuma. Nanso hwɛ yare no ho sɛnkyerɛnne a anibere wom na sɛ ɛba a, ka kyerɛ wo duruyɛfo ntɛm ara.
- Ɛho hia yiye sɛ wobɛkɔ so anom saa aduru yi bere tenten a wo duruyɛfo akyerɛw ama wo no nyinaa.
- Fa ahofadi ne wo duruyɛfo susuw nsɛmmisa anaa nsɛm biara a ɛhaw wo ho. Ɛyɛ wo hokwan.
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