So wo anaa obi a wunim no, wo duruyɛfo ama wo Tamoxifen ama nufu mu kokoram? Anaasɛ wɔakyerɛw wo ama wo esiane sɛ asiane kɛse wom sɛ wubenya kokoram nti? Ɛyɛ ade a ɛfata sɛ wobɛte ehu nka kakra, wopɛ sɛ wuhu nneɛma pii, na wunya nsɛmmisa pii bere a wote aduru yi din no. "So eyi bɛsa kokoram ankasa? Dɛn ne nea efi mu ba?" Ebia woresusuw ho. Enti, ɛnnɛ yɛbɛka nea Tamoxifen yɛ, nea ɛyɛ nipadua no, ne nea ɛsɛ sɛ yɛhu ho asɛm, tiawa koraa, te sɛ nea yɛne yɛn adamfo bi rekasa.
Sɛ yɛbɛka no tiawa a, dɛn ne Tamoxifen?
Tamoxifen yɛ aduru a wɔtaa de sa nufu mu kokoram. Nanso, wɔmfa mma nufu mu kokoram ahorow nyinaa. Wɔde ma nnipa a wɔwɔ nufu mu kokoram a ɛma hormone receptor-positive titiriw .
Dɛn na ɛno kyerɛ? Susuw ho hwɛ, nufu mu kokoram nkwammoaa bi te sɛ nkokoaa a ɔkɔm de wɔn. Wohia hormone abien a yɛn nipadua yɛ fi awosu mu na ama anyin na atrɛw. Wɔn ne estrogen ne progesterone . Nea aduru tamoxifen yɛ ne sɛ esiw saa kokoram nkwammoaa no kwan sɛ wonnya "aduan" a wohia, a ɛyɛ hormone estrogen.
Bio nso, nnuruyɛfo nso kamfo saa aduru yi kyerɛ sɛ wɔmfa nsiw kokoram ano wɔ wɔn a asiane kɛse wom sɛ wobenya nufu mu kokoram no mu (sɛ nhwɛso no, sɛ obi a ɔwɔ abusua no mu anya kokoram, anaasɛ sɛ ɔwɔ awosu mu nsakrae te sɛ (BRCA)).
Mfaso atitiriw bɛn na ɛwɔ tamoxifen ayaresa so?
Saa aduru yi aboa ma wɔagye mmea ɔpepem pii nkwa wɔ wiase nyinaa. Mfaso atitiriw a ɛwɔ so no bi ne:
- Kokoram a ɛbɛsan aba bio a wobesiw ano: Asiane a ɛwɔ hɔ sɛ kokoram bɛsan aba wɔ oprehyɛn, nnuru a wɔde sa yare, anaa mframa a wɔde sa yare akyi no so tew 30% kosi 50%.
- Nufu foforo no ho banbɔ: Wɔ obi a ɔwɔ kokoram wɔ nufu biako mu fam no, asiane a ɛwɔ hɔ sɛ obenya kokoram wɔ nufu foforo a ɛwɔ apɔwmuden no mu no so tew bɛyɛ 50%.
- Kokoram a ɛba no a wobesiw ano: Wɔ obi a ɔwɔ kokoram a ɛba ntɛm (Ductal Carcinoma in Situ anaa DCIS), a ɛwɔ nufu no mu nufusu ntini mu no fam no, ɛtew asiane a ɛwɔ hɔ sɛ obenya kokoram a ɛba no so bɛyɛ 50%.
- Nnompe a ɛhyɛ den: Saa aduru yi nso boa ma wosiw nnompe mu yare ano na ɛhyɛ nnompe mu den, na ebetumi aba bere a obi agyae brayɛ akyi.
- Srade a ɛma mogya mu srade so tew: Ɛboa nso ma srade bɔne a ɛwɔ mogya mu no so tew kodu baabi.
Momma yensua sɛnea wɔnom aduru no ne nea efi mu ba nso ho ade.
Wo duruyɛfoɔ bɛtaa ka akyerɛ wo sɛ fa tamoxifen sɛ aduru (Nolvadex®) anaa sɛ nsuo (Soltamox®) bere koro mu da biara. Bere a wɔde sa yare no betumi ayɛ mfe 5 anaa 10. Wo duruyɛfo na obehu eyi a egyina wo tebea so.
Te sɛ nnuru biara no, tamoxifen betumi de ɔhaw ahorow bi aba. Eyinom mu dodow no ara nyɛ aniberesɛm, na ɛnyɛ obiara na onya bi. Nanso ɛho hia sɛ wohwɛ wɔn yiye.
| Sɛnea nsunsuanso bɔne no te | Nkyerɛkyerɛmu ne sɛnkyerɛnne ahorow |
|---|---|
| Nneɛma bɔne a ɛtaa ba | |
| Nsɛnkyerɛnne a ɛte sɛ nea obi agyae brayɛ | Ɔhyew a ɛyɛ hyew, fifiri a ɛba anadwo, ne ɔbea awotwaa a ɛyɛ kusuu. |
| Mu duru a ɛkɔ soro/ɛhohoro | Nnipa binom mu duru betumi ayɛ kɛse anaasɛ wɔbɛhohoro (edema) wɔ mmeae te sɛ nan. |
| Brayɛ a ɛnkɔ so daa | Brayɛ a ɛnkɔ so daa anaasɛ gyae koraa. |
| Nyarewa nketenkete afoforo | Nan a ɛho ahonhon, akisikuru, nsu a ɛba ɔbea no awotwaa mu, honam ani akisikuru, ɔbrɛ, tiyɛ. Wɔ mmarima fam no, ebia ɔbarima ne ɔbea nna a ɛnyɛ den bɛba. |
| Asiane ahorow a anibere wom nanso ɛntaa nsi a ɛhwehwɛ sɛ wonya ayaresa ntɛm ara | |
| Mogya a ɛtwetwe | Tebea horow te sɛ mogya a ɛtɔ wɔ nan no ntini mu (Deep Vein Thrombosis - DVT) anaasɛ ɔyare a ɛma obi hwe ase. |
| Aniwa a ɛyɛ mmerɛw | Aniwa ho haw te sɛ aniwa a wontumi nhu ade yiye. |
| Awotwaa mu kokoram | Asiane kakraa bi pɛ na ɛwɔ hɔ sɛ obi benya awotwaa mu kokoram. |
Asiane ahorow a anibere wom yi ntaa mma, nanso ɛho hia sɛ wuhu. Wo duruyɛfo rekyerɛw saa aduru yi efisɛ mfaso a ɛwɔ aduru no so no dɔɔso sen asiane ahorow no koraa.
Bere a ɛsɛ sɛ wokɔ oduruyɛfo nkyɛn ntɛm ara no!
Sɛ worenom tamoxifen na wohu sɛnkyerɛnne a edidi so yi mu biara a, ka kyerɛ wo duruyɛfo ntɛm ara anaa kɔ ayaresabea no Dwumadibea a Ɛhwɛ Ntɛmntɛm (ETU) nkyɛn a ɛnntwentwɛn wo nan ase.
- Koko mu yaw mpofirim anaasɛ ɛyɛ den sɛ ɔbɛhome .
- Huraeɛ .
- Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anya ɔyare a ɛma obi hwe ase no bi ne kasa a ɛyɛ mmerɛw , aniwa a enhu ade yiye , ne nsa, nan, anaa anim a ɛyɛ mmerɛw mpofirim .
- Nan, anan, anaa anan a ɛho ahon dodo .
- Ɔfe a wontumi nsiw ano .
Hwɛ yiye wɔ saa nneɛma yi ho bere a worenom nnuru no.
So metumi anom saa aduru yi bere a manyinsɛn no?
Dabi, ɛnte saa koraa. Sɛ wunyinsɛn bere a worenom tamoxifen a, ebia wo ba no benya awo mu dɛmdi a emu yɛ den. Enti, akyinnye biara nni ho sɛ ɛsɛ sɛ wokwati sɛ wubenyinsɛn bere a worenom aduru yi ne asram abien bere a woagyae aduru no akyi. Wo ne wo duruyɛfo nkasa fa ɔkwan a ɛnyɛ hormone a wɔde siw awo ano (te sɛ kɔndɔm) a wode bedi dwuma ho.
So tamoxifen yɛ nnuru a wɔde sa yare?
Dabi, eyinom yɛ nneɛma abien a ɛsono emu biara. Tamoxifen yɛ aduru a wɔde sa hormone . Titiriw no, ɛka nnuru kuw bi a wɔfrɛ no Selective Estrogen Receptor Modulators - SERMs. Nnuru a wɔde sa yare yɛ ayaresa a ekum nkwammoaa a ɛpaapae ntɛmntɛm (kokoram nkwammoaa ne nkwammoaa a wɔwɔ apɔwmuden nso). Nanso tamoxifen de n’ani si hormone dwumadi nkutoo so.
So nnuan anaa anonne bi wɔ hɔ a ɛsɛ sɛ mekwati bere a merenom aduru yi?
Aane. Nnuan ne anonne bi betumi atew tamoxifen a etu mpɔn no so, enti nyansa wom sɛ wobɛkwati.
- Borɔdɔma a wɔfrɛ no grapefruit
- Tangerines a wɔde yɛ nneɛma
- Nsã biara a nsa wom
Nkrasɛm a Wɔde Kɔ Fie
- Tamoxifen yɛ aduru a etu mpɔn kɛse a egye nkwa ma nufu mu kokoram a egyina hormone so.
- Ɛho hia sɛ wobɛnom w’aduru no sɛnea wo duruyɛfo akyerɛ wo no pɛpɛɛpɛ, bere a ɛfata, ne bere tenten a ɛfata.
- Nsuro sɛ nea ebefi mu aba no, nanso hwɛ yiye. Hwɛ yiye titiriw wɔ sɛnkyerɛnne ahorow a ɛkyerɛ sɛ mogya atɔ anaa akisikuru (nan a ɛho ahonhon, koko mu yaw, kasa a ɛyɛ mmerɛw) ho. Sɛ wuhyia eyinom mu biara a, hwehwɛ aduruyɛfo afotu ntɛm ara.
- Nnyinsɛn bere a worenom saa aduru yi ne asram 2 bere a woagyae no. Wo ne wo duruyɛfo nkasa mfa ɔkwan a ahobammɔ wom a wode siw awo ano a wode bedi dwuma no ho.
- Wo ne wo duruyɛfo nka nsɛmmisa, ehu, anaa adwenem naayɛ biara a ebia wowɔ ho asɛm pefee. Wɔyɛ krado bere nyinaa sɛ wɔbɛboa wo.
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