Akyi yaw a ɛtaa yɛ, ɛyɛ den... So eyi yɛ Ankylosing Spondylitis (AS)?

So wotaa te yaw wɔ w’akyi ne w’asen mu nso fi wo mmofraase? Titiriw sɛ wosɔre anɔpa a, so w’akyi te nka sɛ ɛyɛ den na ɛyɛ den sɛ wobɛkotow anaa wobɛyɛ adwuma biara kakra? Yɛn werɛ taa fi nneɛma a ɛtete saa, na yesusuw sɛ "ebia ɛyɛ akisikuru" anaasɛ "ebia efi ɔbrɛ a efi adwuma mu." Nanso, eyi betumi ayɛ tebea a ehia sɛ wɔde wɔn adwene si so kakra. Ɛnnɛ yɛreka yareɛ bi a ɛte sɛ yei, na nnipa bebree nnim no yie, nanso ɛho hia paa sɛ yɛma yɛn ani da hɔ. Ɛno ne Ankylosing Spondylitis .

Dɛn ne Ankylosing Spondylitis (AS) tiawa?

Sɛ yɛbɛka no tiawa a, ɛyɛ ntini mu yare bi a ɛka akyi berɛmo no nkwaa. Ɛka w’akyi berɛmo ne sacroiliac nkwaa titiriw, baabi a w’akyi berɛmo no fã a ɛwɔ fam no ne w’asen nnompe di nkitaho no. Saa yare yi ma wo nipadua mu tumi a ɛko tia nyarewa no di mfomso tow hyɛ saa nkwaa yi so, na ɛde ɔfe a enni sabea ba .

Bere a saa ɔfe yi kɔ so bere kɔ so no, ebetumi ama akyi ne asen ayɛ no yaw, ama akyi berɛmo no atumi ayɛ nsakrae, na asiw kankyee ano . Nnipa binom mpo betumi ayɛ wɔn kɔn a ɛyɛ den bere a bere kɔ so no.

Wɔkyerɛ sɛ ebia nnipa 1,000 biara mu biako wɔ wiase nyinaa. Aduru biara nni hɔ a wɔde bɛsa eyi de besi nnɛ. Nanso mma ɛnhaw wo , sɛ wohu yare no yiye na wɔsa no wɔ oduruyɛfo a ɔfata afotu ase a, wubetumi adi saa yare yi so yiye na woatra ase sɛnea ɛsɛ.

Henanom na wɔwɔ asiane kɛse mu sɛ wobenya saa yare yi?

Dɛn nti na nnipa binom nya saa yare yi? Ɛwom sɛ wonhuu nea ɛde ba ankasa de, nanso nyansahufo ahu nneɛma pii a ɛma asiane no yɛ kɛse.

Awosu mu nkɛntɛnso (Awosu mu nkwaadɔm) .

Wɔahu sɛ awosu mu nkɛntɛnso na ɛde yare yi ba titiriw.

• HLA-B27 awosu mu abɔde: Eyi ne awosu mu abɔde a ɛne yare yi wɔ abusuabɔ kɛse. Saa awosu mu abɔde yi boa yɛn nipadua mu nipadua mu ahoɔden a ɛko tia nyarewa no ma wohu ‘eyinom yɛ yɛn ankasa nkwammoaa’ ne ‘ahɔho mmoawa anaa mmoawa’. Nnipa a wɔwɔ saa awosu mu abɔde yi fã pɔtee bi (HLA-B27 soronko no) wɔ asiane kɛse mu sɛ wobenya AS.
• Adeɛ a ɛho hia paa: Nanso adeɛ a ɛho hia paa wɔ ha ne sɛ ɛnam sɛ wowɔ saa HLA-B27 gene yi wɔ wo nipadua mu nti, worentumi nka sɛ wobɛnya saa yareɛ yi. Nnipa dodow no ara a wɔwɔ saa awosu mu abɔde yi rennya saa yare yi da. Afei nso, nnipa a wonni saa awosu yi nso betumi anya saa yare yi.
• Awosu mu nkwaadɔm afoforo: Bio nso, wɔahu sɛ awosu mu nkwaadɔm afoforo pii a ɛfa nipadua no mu tumi a ɛko tia nyarewa ho, te sɛ ERAP1, IL1A, ne IL23R, ne yare yi wɔ abusuabɔ.

Tebea Afoforo a Ɛma Ɔhyew

Ebia nnipa binom a wɔwɔ AS nso benya ɔyare afoforo a ɛma obi ho hyehye no. Nhwɛsoɔ:

• Psoriasis a ɛyɛ mmerɛw
• Akisikuru a Ɛyɛ Akisikuru
• Crohn yare no

Enti, sɛ obi wɔ w’abusua mu wɔ saa tebea horow yi, anaa Ankylosing Spondylitis a, ebia wo nso wobɛkɔ asiane mu.

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Sɛnea ɔbarima ne ɔbea nna ne mfe a obi adi ka

AS ho sɛnkyerɛnne taa fi ase ansa na wadi mfe 40. Ɛtɔ da bi a, sɛnkyerɛnne ahorow no tumi ba ntɛm ara wɔ mfe 16 mu, a wɔfrɛ no juvenile-onset ankylosing spondylitis.

Ɛsono ɔkwan a yare yi fa so yɛ n’ade, na egyina ɔbarima ne ɔbea nna so. Sɛ wuhu nsonsonoe ahorow yi a, ɛbɛboa kɛse ma wɔahu yare no ntɛm.

Ade biako nti a mmea taa twentwɛn wɔn nan ase sɛ wobenya yare no ne adwene a ɛnteɛ a ɔmanfo ne ebia nnuruyɛfo mpo nya sɛ eyi yɛ ‘mmarima yare’. Afei nso, esiane sɛ ɛsono mmea yare no ho sɛnkyerɛnne wɔ mmarima de ho (ebia MRI scan mpo bɛkyerɛ sɛ akyi berɛmo no nsɛe pii) nti, ebetumi agye bere ansa na wɔahu yare no.

So abusuakuw ne abusuakuw a wofi mu nso di dwuma bi?

Yiw, abusuakuw di dwuma bi kodu baabi. Nhwehwɛmu ahorow ada no adi sɛ saa yare yi abu so wɔ aborɔfo mu, titiriw wɔ Europa kusuu fam aman mu. Ɛntaa mma Afrikafo a wɔyɛ abibifo mu.

Nanso asɛm bi a ɛho hia wɔ ha. Ɛwom sɛ asiane a ɛwɔ hɔ sɛ obenya yare no sua de, nanso nhwehwɛmu ahorow kyerɛ sɛ sɛ abibifo nya AS a, wobetumi ama yare no mu ayɛ den .

Afei nso, ɛkame ayɛ sɛ aborɔfo a wɔwɔ AS no mu 90% na wɔwɔ HLA-B27 awosu mu abɔde. Nanso, abibifo a wɔwɔ AS no mu 50%-60% pɛ na wɔwɔ saa awosu mu abɔde yi. Enti, ɛho hia sɛ wususuw abusuakuw ne awosu a wofi mu ho bere a worehu yare no.

Nhwehwɛmu a wɔkyɛe ne nkɛntɛnso a enya

Wɔ nnipa pii fam no, egye bɛyɛ mfe 8 kosi 10 ansa na wɔahu yare no yiye bere a yare no ho sɛnkyerɛnne afi ase no. Saa akyɛde yi betumi akyɛ mpo ama mmea, titiriw.

Saa akyɛde yi ma wɔkyɛ ayaresa. Eyi ma ɔsɛe a yare no betumi de aba no yɛ kɛse. Bere kɔ so no, nnompe a ɛwɔ akyi berɛmo no mu no tumi bom (fusion), na akyi berɛmo no kankan betumi ayera koraa.

Ɛho hia sɛ wohu yare no ntɛm na wɔsa yare na ama wɔanya akwahosan pa na wɔadi yare no ho dwuma.

Enti, sɛ w’akyi yɛ wo yaw bere nyinaa, anɔpa a wo ho yɛ wo den, anaa sɛnkyerɛnne afoforo, titiriw sɛ woyɛ ɔbea a , yɛsrɛ wo mmu w’ani ngu so. Hwɛ oduruyɛfo a ɔfata na ka wo sɛnkyerɛnne ahorow no ho asɛm pefee. Nsuro sɛ wobɛsrɛ sɛ wɔnyɛ wo X-ray anaa MRI scan sɛ ɛho hia a. Wowɔ hokwan sɛ wokasa ma wo ho.