Yala i delila k’i yɛrɛ ɲininka o joli min bɛ an farikolo kɔnɔ, o bɛ bɔ yɔrɔ min na ani a bɛ dilan cogo min na wa? An b’a dɔn ko nin joli in nafa ka bon kosɛbɛ walasa k’an to kɛnɛya la, k’an tanga banaw ma, ani ka oksizɛni ta ka taa an farikolo yɔrɔ bɛɛ la. O la bi an bɛna kuma nin wale kabakoma in kan, o kɔrɔ ye ko an farikolo bɛ joli kuru kura dilan a yɛrɛ ma. A bɛ iko izini fitinin dɔ farikolo kɔnɔ.
Joli bɔli ye mun ye?
N’an y’a fɔ cogo nɔgɔman na, joli-sira-funu ye joli-sira-funu ye an farikolo kɔnɔ. Ni joli kuru kɔrɔw bɛ sa, joli kuru kura ka kan ka bɔ tuma bɛɛ walasa ka bila u nɔ na. Ni olu tɛ yen, an ka joli sɔrɔli bɛna tiɲɛ. O wale in bɛ daminɛ sani an ka bange, wa a bɛ taa ɲɛ sɛgɛsɛgɛli la an ka ɲɛnamaya bɛɛ kɔnɔ.
Nin daɲɛ in bɛ se ka fɔ ko a ka gɛlɛn dɔɔnin, nka a kɔrɔ ka nɔgɔn kosɛbɛ. A bɛ Kɛ ni Gɛrɛkikan daɲɛ fla ye:
- Haîma (Haima): kɔrɔ ye "joli".
- Poiēsis: kɔrɔ ye "ka fɛn dɔ dilan".
Sisan, i y’a faamu, tiɲɛ tɛ? Ni nin daɲɛ fla ninnu farala ɲɔgɔn kan, u kɔrɔ ye "joli bɔli". Tuma dɔw la, daɲɛw i n’a fɔ `(hemopoiesis)` ani `(hematogenesis)` fana bɛ Kɛ o la.
Jolikisɛ suguya jɔnjɔn jumɛnw bɛ sɔrɔ o kɛcogo fɛ?
An joli bɛ kɛ ni farikolokisɛ suguya wɛrɛw dalajɛlen ye. Nin farikolokisɛ suguya ninnu bɛɛ bɛ sɔrɔ joli-sira-funu kɛcogo la. An k’a lajɛ suguya kunbabaw ye minnu ye ani u ka baara ye mun ye.
| Joli kuru suguya | Baara ka nɔgɔn. |
|---|---|
| Joli kuru bilenmanw walima Ɲɛgɛnɛsiraw | Olu ye ‘jigin baara’ ye min bɛ oksizɛni ta an fogonfogon la k’a ta ka taa farikolo yɔrɔ ni farikolo yɔrɔ tɔw bɛɛ la. U bɛ gazi ɲuman fɛnɲɛnamafagalanw fana ta minnu bɛ bɔ farikolokisɛw fɛ ka segin fogonfogon la. Joli kuru bilenmanw ka ca an joli la. ninnu dilanni taabolo bɛ wele ko Erythropoiesis . |
| Joli kuru finmanw walima joli-sira-funu | Olu ye an farikolo ka ‘kɛlɛbolo’ ye. O joli kuru finmanw b’an tanga banaw ma, u kɛtɔ ka dunanw ka binkannikɛlaw kɛlɛ i n’a fɔ tumuw, banakisɛw ani banakisɛw. U bɛ dɛmɛ fana ka farikolokisɛw tiɲɛ minnu tɛ cogo la, minnu bɛ sɔrɔ farikolo kɔnɔ. u dilanni taabolo bɛ wele ko leukopoiesis . |
| Plaquettes walima Thrombocytes (banakisɛfagalanw). | Miiri k’a filɛ min bɛna kɛ n’i y’i bolo tigɛ. Waati dɔ tɛmɛnen kɔ, joli bɛ jɔ, tiɲɛ tɛ? O de ye joli segin furakisɛw dɛmɛni ye. Olu ye selilɛriw ye minnu bɛ nɔrɔ. Ni joginda bɛ yen, u bɛ ɲɔgɔn dalajɛ ka kɛ kurukuru ye, ka joli jɔ. ninnu dilanni taabolo bɛ wele ko trombopoïèse . |
Yala joli kuru finman suguya dɔw bɛ yen wa?
Ɔwɔ, i n’a fɔ an ka sɔrɔdasiw la cogo min na, joli kuru finman suguya wɛrɛw bɛ yen. Baara kɛrɛnkɛrɛnnen dɔ bɛ u kelen-kelen bɛɛ fɛ. A suguba minnu bɛ yen olu ye :
- Neutrophils (banakisɛfagalanw).
- Basofiliw (Basophiles) ye
- Eosinofiliw (Eosinophiles) (Eosinophiles).
- Monocytes (banakisɛfagalanw).
- Lanposotiw - Olu bɛ tila ka taa a fɛ ka kɛ B-cell, T-cell ani Natural Killer cellules ye.
O joli bɔli bɛ kɛ min tiɲɛ na?
iziniba min bɛ o jolikisɛw dilan , o bɛ an kolotugudaw kɔnɔ . Kolotuguda ye fɛn nɔgɔlen ye min bɛ i n’a fɔ ɛponji an ka kolo belebelebaw kɔnɔ. Jolikisɛw bɛ dilan kolotugudaw la, o kɔfɛ, o bɛ fara an ka joli siraw kan.
Hali ni a ka ca a la joli bɛ bɔ kolotugudaw la, ko kɛrɛnkɛrɛnnen dɔw la, misali la, ni bana dɔ donna kolotuguda la min b’a bali ka joli dilan, farikolo yɔrɔw i n’a fɔ an ka sugunɛ ni an ka sugunɛ fana bɛ se ka joli bɔli daminɛ.
Nka o joli bɛ bɔ yɔrɔ minnu na, olu tɛ kelen ye dɔɔni sani an ka bange ani an bangenen kɔfɛ.
Sani a ka bange (den kɔnɔbara la) .
Kɔnɔmaya dɔgɔkun fɔlɔw la, joli bɛ bɔ fɛn dɔ la min bɛ wele ko wuluwulu. O kɔ, ni kɔnɔmaya bɛ taa ɲɛ, o baara bɛ taa sugunɛ ni sugunɛ na. Kɔnɔmaya kalo duurunan ɲɔgɔn na, joli bɛ daminɛ ka bɔ kolotugudaw de la kosɛbɛ.
Bange kɔfɛ
K’a ta an wolo don na fo ka se balikuya ma, kolotuguda de ye joli kuruw dilanyɔrɔba ye. Nka, joli kuru finman sugu dɔ fana bɛ sɔrɔ yɔrɔ minnu na i n’a fɔ timi, olu ye ɲɛgɛnɛsira dɔ ye, ka fara kolotuguda kan.
Joli bɔli taabolo bɛ kɛ cogo di?
O wale bɛɛ bɛ daminɛ ni seli kɛrɛnkɛrɛnnen kelen ye. O bɛ wele ko Hematopoïétique Stem Cell (HSC).An k'o Weele ko "seli ba" walima "seli fɔlɔ". Nin denba in bɛ se ka kɛ joli kuru bilenman ye, joli kuru finman, joli segin, joli kuru suguya o suguya.
Miiri o la i n’a fɔ bɔgɔmugu. I n’a fɔ bɔgɔdaga la, bɔgɔmugu dɔ bɛ se ka kɛ ka daga, tasa walima fɛn wɛrɛ dilan, joli kuru suguya bɛɛ bɛ se ka dilan ni o HSC selilɛri ye.
O HSC selilɛri in bɛ fɔlɔ ka kɛ seli "precursor" ye. O kɔfɛ, o farikolokisɛ ɲɛbila in bɛ tila ka danfara don ɲɔgɔn na siɲɛ caman wɛrɛ, ka laban ka kɛ joli kuru bilenman, joli kuru finman walima joli segin furakisɛ ye min yiriwara kosɛbɛ.
- Joli kuru bilenmanw bɔli (Erythropoiesis): HSC selilɛri bɛ yiriwa ka kɛ joli ɲɛfɛla ye min bɛ wele ko ``erythroblast'', o laban bɛ kɛ joli kuru bilenman ye.
- Joli kuru finmanw bɔli (Leukopoiesis): A bɔli sira fila bɛ yan. Joli kuru finman dɔw bɛ bɔ ``miyɛloyi selilɛri`` sira fɛ, ani lanposotiw bɛ bɔ ``limfoyidi `` sira fɛ.
- Plaquettes production (Thrombopoiesis): HSC selilɛri bɛ yiriwa ka kɛ selilu belebele ye min bɛ wele ko ``megakaryocyte.'' O kɔfɛ, joli segin furakisɛw bɛ dilan ni u tilalen don yɔrɔw ye ka bɔ o selilɛriba in na.
Ni gɛlɛya dɔ bɛ o kɛcogo la do?
An farikolo bɛ se kosɛbɛ o joli-sira-funu ninnu bɔli kɔlɔsili la. O kɔrɔ ye ko an mago bɛ selilu hakɛ min na, an bɛ o dɔrɔn de dilan. Nka bana dɔw bɛ se ka nin wale in ɲagami. O kɔ, joli kuru damadɔ bɛ se ka bɔ, walima joli bɛ se ka caya kojugu. O fila si man ɲi farikolo ma.
| Joli kuru suguya | Ni selilu hakɛ dɔgɔyara (Too Few) . | Ni selilu hakɛ cayara (Too Many) . |
|---|---|---|
| Joli kuru bilenmanw | o bana in bɛ wele ko jolidɛsɛ . Farikolo bɛ sɛgɛn ani ka barika dɔgɔya barisa farikolokisɛw tɛ oksizɛni sɔrɔ u mago bɛ min na. | o bana in bɛ wele ko Erythrocytose . A bɛ se ka kɛ sababu ye ka joli kuru, ka dɔ fara bana dɔw kan i n’a fɔ dusukun tantanni walima kirinni. |
| Joli kuru finmanw | o bana in bɛ wele ko Leukopenie . Ni joli kuru finmanw ka dɔgɔn, farikolo tangacogo bɛ dɔgɔya, wa banakisɛw bɛ se ka sɔrɔ tuma caman. | o bana in bɛ wele ko Leukocytose . A ka ca a la a bɛ sɔrɔ ni aw bɛ banakisɛ dɔ kɛlɛ. Nka a bɛ se ka kɛ fana jolilabana dɔw la walima kansɛri bana dɔw la. |
| Plaquettes (banakisɛfagalanw). | o bana in bɛ wele ko Thrombocytopenie . Hali joginda fitini dɔ bɛ se ka kɛ sababu ye ka joli bɔ min tɛna jɔ. Kurukuruw fana bɛ se ka kɛ fari la. | O bana in bɛ wele ko trombocytose , wa a bɛ dɔ fara joli kuru faratilenw sɔrɔli kan joli siraw kɔnɔ. |
Ko jumɛnw bɛ joli-sira-funu kɛcogo bali?
O joli bɔli taabolo bɛ se ka tiɲɛ kun caman kosɔn.
- Kɔrɔya: Ni an bɛ kɔrɔbaya, tulumafɛnw bɛ se ka caya kolotugudaw la, o bɛ dɔ bɔ joli kuruw dilanni seko la.
- Jolibanaw ni kansɛri: Kansɛriw i n’a fɔ jolidɛsɛ, jolidɛsɛ, ani miyɛloma, olu bɛ se ka kɛ sababu ye ka joli kuru caman sɔrɔ minnu tɛ baara kɛ ka ɲɛ.
- Fura dɔw: Misali la, chimiothérapie min bɛ kɛ kansɛri la, o tɛ se ka kansɛri banakisɛw dɔrɔn faga, nka a bɛ se ka joli kuru kɛnɛmanw fana faga. Nin ye fura dɔw kɔlɔlɔ ye.
Ni bana taamasiɲɛw bɛ aw la i n’a fɔ aw bɛ sɛgɛn tuma bɛɛ, ka to ka farigan ni banakisɛw sɔrɔ, ka kurukuru kun tɛ, walima ka joli bɔ joginda la min bɛ waati jan ta ka a jɔ, aw ye aw jija ka kuma aw ka dɔgɔtɔrɔ fɛ. Olu bɛ se ka kɛ joli gɛlɛya taamasiɲɛw ye.
Joli bɔli ye wale ye min bɛ kɛ tuma bɛɛ, min nafa ka bon an ka ɲɛnamaya kama. Nin izini fitinin in min bɛ an kolotugudaw kɔnɔ, o de b’an to kɛnɛya la ani ka barika sɔrɔ. O de kama a nafa ka bon kosɛbɛ k’an janto an joli kɛnɛya la.
Take-Home cikan
- Joli-sira-funuA bɛ tali kɛ fɛɛrɛ min na an farikolo bɛ joli kurukuruw bɔ minnu bɛ wele ko joli kuru bilenmanw, joli kuru finmanw ani joli segin furakisɛw.
- O kɛcogo in bɛ Kɛ kosɛbɛ kolotugudaw la an kolo kɔnɔ.
- Joli kuru bilenmanw bɛ oksizɛni ta, joli kuru finmanw b’an tanga banaw ma, joli kuru bilenmanw bɛ joli dabila ni an joginna.
- Ni joli kuru hakɛ dɔgɔyara walima ka caya ka tɛmɛ a cogo kɔrɔ kan, o bɛ se ka kɛ sababu ye ka furakɛli cogoya suguya caman sɔrɔ.
- Ni aw ye bana taamasiɲɛw ye i n’a fɔ sɛgɛnba min ɲɛfɔlen tɛ, banakisɛw bɛ to ka bɔ aw la, walima joli bɔli min tɛ deli ka kɛ, a nafa ka bon aw ka taa dɔgɔtɔrɔso la joona walasa ka laadilikan sɔrɔ.
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