Ðe teƒe dzĩwo hã nɔa wò ŋutilã ŋu ne èfi fi alo nèle dzo dama? Esia ku ɖe (Cholinergic Urticaria) ŋu!

Ðe teƒe suesuesue siwo biã, siwo le ʋuʋum le wò ŋutilã ŋu ɣeaɖewoɣi ne èle kame dem, alo ne èdo go le ŋdɔ me, alo ɖewohĩ ne èɖu nuɖuɖu siwo me wodea nu ʋeʋĩiwoe eye fifia nèle fifiaa? Enye nusi sɔ be vɔvɔ̃ naɖo ame vie ne edzɔ nenema. Le ame aɖewo gome la, esia ate ŋu adzɔ zi geɖe gɔ̃ hã. Eyata egbea, mina míaƒo nu tso nusi woyɔna be esia le atikewɔwɔ me, nusita wòdzɔna, kple nusi woate ŋu awɔ tso eŋu ŋu.

Nukae nye esia (Cholinergic Urticaria)? Mina míase egɔme bɔbɔe ŋutɔ!

Kpuie ko la, Cholinergic Urticaria nye ʋuʋudedi ƒomevi aɖe si le dzo dam, si kɔ, eye wòʋãna (hives) si dzena le wò ŋutigbalẽ ƒe anyime ne wò ŋutilã ƒe dzoxɔxɔ dzi ɖe edzi eye nèdze fifia gɔme. Le nyateƒe me la, esia nye wò ŋutilã ƒe dɔlélenutsiŋutete ƒe ŋuɖoɖo. Ðeko wòle abe ɖe dzoxɔxɔ ƒe nulɔdɔ le wò ŋutilã ŋu ene. Ame aɖewo hã yɔnɛ be "dzoxɔxɔ ƒe ʋuʋudedi" alo "dzoxɔxɔ ƒe ʋuʋudedi," si fia dzoxɔxɔ ƒe ʋuʋudedi alo fifia ƒe ʋuʋudedi.

Nɔnɔme sia ate ŋu adze ame sia ame dzi, gake zi geɖe la, dzesi siawo dzena zi gbãtɔ le sɔhɛ siwo xɔ tso ƒe 10 va ɖo ƒe 30 ŋu.

Nya "cholinergic" fia atike ƒe dɔla si le míaƒe lãmekawo me si woyɔna be acetylcholine (Ach). Míaƒe lãmeka siwo nye parasympathetic nervous system ye ɖea esia ɖe go. "Urticaria" nye atikewɔwɔ me ŋkɔ na ŋutigbalẽ ƒe ʋuʋudedi ƒomevi siawo .

Ðe nɔnɔme sia (Cholinergic Urticaria) dzɔna le ame geɖe mea?

Ẽ, mebɔ abe alesi nàsusui ene o. Bu eŋu kpɔ ko, abe ame ɖeka le atɔ̃ ɖesiaɖe me axɔ atɔ le woƒe agbemeŋkeke aɖe me. Cholinergic Urticaria nye nɔnɔme si hea aɖuɖɔtoe siwo tso ŋutilã me nu (abe dzoxɔxɔ, vuvɔ, alo nuteɖeamedzi ene) gbɔ. Ame siwo ƒe aɖuɖɔtoe si nɔa anyi didi wu kwasiɖa ade, alo aɖuɖɔtoe si nɔa anyi didi le la dometɔ siwo ade 7% ŋue dɔléle sia le. Eyata ne esia le dzɔdzɔm ɖe dziwò la, nyae be menye wò ɖeka koe o.

Nukatae míexɔa Cholinergic Urticaria?

Eŋutinunyalawo menya nusi tututu hea esia vɛ haɖe o. Gake nukpɔsusu vevi ɖeka aɖe li. Eyae nye be míaƒe cholinergic nervous system ƒe dɔwɔwɔ gbɔe wòtsona. Alesi wosusu be edzɔnae nye esi:

1. Ne wò ŋutilã ƒe dzoxɔxɔ dzi ɖe edzi la, èdzea fifia gɔme. Esia sɔ eye wòkpena ɖe wò ŋutilã ŋu wòfa.

2. Le esia ta la, wò lãmekawo ɖea atike aɖe si woyɔna be ``acetylcholine'' tso lãmeka ƒe nuwuwu siwo te ɖe wò ŋutigbalẽ ƒe anyime ŋu.

3. Ne `(acetylcholine)` sia ka wò ŋutigbalẽa la, eʋãa ŋutigbalẽa, si wɔnɛ be nulɔdɔa dzɔna, si wɔnɛ be teƒe mawo siwo ʋãna (hives) eye ɖewohĩ wòvuvuna.

Kpuie ko la, ɖeko wòle abe wò ŋutigbalẽ sea veve vie na atike aɖe si dona ne èfi fi.

Nukawoe nye afɔku siwo ate ŋu ana woaxɔ Cholinergic Urticaria?

Afɔku nye nane si dzia mɔnukpɔkpɔ si li be woaxɔ dɔléle aɖe ɖe edzi. Ne aɖuɖɔtoe si nɔa anyi didi le ŋuwò la, anɔ eme be Cholinergic Urticaria adze dziwò. Hã:

• Ne ``Allergic rhinitis (hay fever)`` (nulɔdɔ si sɔ kple hay fever) le ŋuwò .
• Ne `(Asrã)` le ŋuwò .
• Ne eczema le ŋuwò la .
• Ne Cholinergic Urticaria alo aɖuɖɔtoe si nɔa anyi didi le wò ƒomea me .
• Hyperhidrosis nye nɔnɔme si me nèfiãna wu alesi wòle dzɔdzɔmee .

Menye ɖe amesiame si si nu siawo le la axɔ nusia o, gake afɔkua lolo vie.

Nukawo koŋue ʋãa teƒe siawo?

Nukutɔe la, le ame siwo ade enyi le ewo ɖesiaɖe me gome la, nusi koŋ gbɔ cholinergic ƒe teƒe siawo tsonae nye kamedede alo kamedede. Tsɔ kpe ɖe eŋu la, susu bubu geɖewo hã li:

• Dzimaɖitsitsi nye vɔvɔ̃ alo dzitsitsi si me susu mele o.
• Ne èse le ɖokuiwò me be yedo dziku, lé blanui, alo be yeƒe dzi gbã.
• Ne ètso teƒe si fa miamiamia yi xɔ si me dzoxɔxɔ le me alo yi ɣe ƒe keklẽ sesẽ si le gota la me zi ɖeka.
• Elabena ne asrã le ŋuwò la, wò ŋutilã xɔa dzo.
• Yame xɔa dzo, vevietɔ le ŋkeke siwo dzi ŋdɔ ʋuna abe Sri Lanka ene.
• Nuwo abe tsileƒe dzodzoewo, sauna, kple tsi dzodzoewo ene.
• Ne èɖu nuɖuɖu siwo me wodea nu ʋeʋĩiwoe la, elabena wonana wò ŋutilã xɔa dzo hefiãna.
• Nuteɖeamedzi.
• Ate ŋu atso aŋe siwo me ya kple tsi megena ɖo o siwo wozãna tsɔ tsyɔa abi dzi be ya kple tsi nagage ɖe eme o hã gbɔ.

Nukae nye Cholinergic Urticaria ƒe dzesiwo?

Zi geɖe la, dzoxɔxɔ ƒe ʋuʋu dzea egɔme le aɖabaƒoƒo ʋɛ aɖewo megbe tso esime nèfi fi. Woate ŋu anɔ anyi aɖabaƒoƒo 20 va ɖo 30. Gake wole ame aɖewo si wu gaƒoƒo ɖeka. Wokpɔa wo zi geɖe le wò asiwo, mo, kple akɔta ƒe akpa si le etame.

Teƒe siawo ate ŋu adze abe pinpoints dzĩ suesuesuewo ene le anyigba si biã (erythema) dzi. Alo, teƒe sue siawo ate ŋu aƒo ƒu awɔ ʋuʋudedi gã siwo kɔ ɖe dzi.

Aleke wò ŋutilã sena le eɖokui me ne teƒe siawo do?

Ame si ŋu Cholinergic Urticaria le ate ŋu akpɔ dzesi siwo gbɔna ne teƒe siawo dze:

• Ʋuʋudedi geɖe.
• Dzobibi ƒe seselelãme aɖe.
• Ewɔna nam abe ɖe wòle ʋuʋum ene.
• Esenɛ le eɖokui me be dzoxɔxɔ le ye ŋu ne woka asi eŋu.

Ðe dzesi bubu aɖewo li siwo ate ŋu akpe ɖe teƒe siawo ŋua?

Esia mebɔ vie o, si fia be medzɔna ɖe amesiame dzi o, gake ame aɖewo ateŋu akpɔ dzesiwo abe esiawo ene kpe ɖe Cholinergic Urticaria ŋu:

• Aɖuɖɔɖɔɖɔ.
• Syncope (si nye lãmetutudɔ).
• Taɖuame.
• Dzi ƒe tsotso.
• Yagbɔgbɔ sesẽ (gbɔgbɔtsixetsixe).
• Nuɖuɖumadzroame alo aɖuɖɔtoe.
• Ʋuʋudedi.

Ne èkpɔ teƒe siwo dzesi siawo le la, ele vevie be nàyi ɖɔkta gbɔ godoo be wòaɖo aɖaŋu na wò.

Aleke ɖɔkta wɔa anya dɔléle sia (Cholinergic Urticaria)?

Ne ɖɔkta aɖe susu be dzoxɔxɔ le ŋuwò la, anɔ eme be woaɖo wò ɖe nulɔdɔŋutinunyala alo ŋutigbalẽŋutinunyala gbɔ . Woado wò ŋutigbalẽ kpɔ eye woaɖo to wò dzesiwo nyuie.

Woate ŋu awɔ dodokpɔ aɖewo abe esiawo ene hã:

• Kamedede ƒe dodokpɔwo: Wonana fifia nɔa ŋuwò ne èƒua du le afɔdzideƒe, gasɔ si le teƒe ɖeka dodo, alo dɔwɔnu bubuwo zazã me.
• Wodoa atike sue aɖe si woyɔna be ``(methacholine)'' be woakpɔ alesi wò ŋutilã sea veve ɖe cholinergic atikewo nu.
• Dzoxɔxɔ dodokpɔwo: Wodoa wò ŋutilã ƒe dzoxɔxɔ ɖe dzi ne èbɔbɔ nɔ tsi dzodzoe me hena ɣeyiɣi aɖe alo ne èbɔbɔ nɔ xɔ si me dzoxɔxɔ le me.

Dodokpɔ siawo koe nye mɔ si dzi nàto aɖo kpe edzi nenye be Cholinergic Urticaria alo nu bubu aɖe le ŋuwò ŋutɔŋutɔ.

Nukae woate ŋu awɔ be woakpɔ gbɔdzɔe tso nɔnɔme sia (Cholinergic Urticaria) me?

Nya nyui aɖe li! Ne èle tsitsim la, dɔlélea ƒe sesẽme (Cholinergic Urticaria) kple atɔ ƒe ʋuʋu zi gbɔ zi geɖe ate ŋu aɖe akpɔtɔ. Ate ŋu nu ayi keŋkeŋ le ƒe ʋɛ aɖewo ko me gɔ̃ hã. Hafi ɣemaɣi naɖo la, wò ɖɔkta ate ŋu aɖo aɖaŋu le atikewɔmɔnu siawo tɔgbe ŋu be wòakpe ɖe ŋuwò nàkpɔ wò dzesiwo gbɔ:

• Antihistamines: Esiawoe nye atike siwo wozãna wu tsɔ ɖea ʋuʋudedi kple ʋuʋudedi dzi kpɔtɔna.
• Atike aɖewo siwo wonana na asrã.
• Ʋu ƒe sisi ƒe atike aɖewo.
• Anticholinergics nye atike siwo ɖea fifia dzi kpɔtɔna.

Wò ɖɔkta atso nya me le atikewɔwɔ si anyo na wò ŋu.

Ðe esia (Cholinergic Urticaria) ate ŋu ahe kuxi bubuwo vɛa?

Esia mebɔ kura o, gake ɣeaɖewoɣi la, nulɔdɔ sesẽ aɖe si woyɔna be ``anaphylaxis'' ateŋu adzɔ kple kamedede (Cholinergic Urticaria).Anaphylaxis nye dɔléle si ate ŋu ade ame ƒe agbe afɔku me si me yaƒoƒomɔ̃wo vuvu, si wɔnɛ be gbɔgbɔ sesẽna.

Ne esia dzɔ ɖe dziwò alo ame aɖe si nènya dzi la, ƒo ka na 1990 Suwaseriya Ambulance Service enumake alo yi kɔdzi kaba ale si nàte ŋui. Ne ènya be yele afɔku me be yeƒe nulɔdɔ sesẽ aɖe nadze ye ŋu la, nunya le eme hã be nàtsɔ `(epinephrine injector (EpiPen®))` ɖe asi. Ðo dze kple wò ɖɔkta tso esia ŋu eye nàdi aɖaŋuɖoɖo.

Ɣeyiɣi didi kae nɔnɔme sia (Cholinergic Urticaria) nɔa anyi?

Zi geɖe la, cholinergic Urticaria nyona ɖe edzi le ɣeyiɣi aɖe megbe, ɣeaɖewoɣi gɔ̃ hã wònyona ɖe edzi keŋkeŋ. Ame siwo ŋu dɔléle sia le dometɔ siwo ade 15% hayana keŋkeŋ tso woƒe dzesiwo me. Eyata mègatsi dzi o.

Ðe woate ŋu axe mɔ ɖe Cholinergic Urticaria nu keŋkeŋa?

Ne míagblɔe tututu la, màte ŋu adzudzɔ fifia alo dzoxɔxɔ keŋkeŋ o. Enye dzɔdzɔmenu si kpena ɖe míaƒe ŋutilã ŋu wòfa eye wòɖɔa eƒe dzoxɔxɔ ɖo. Azɔ hã, menyo be míadzudzɔ kamedede, si nye kamedede o, elabena emae nana míenɔa lãmesẽ me.

Gake nu ʋɛ aɖewo li nàte ŋu awɔ atsɔ aɖe dzoxɔxɔ ƒe afɔku si le ŋuwò be nàxɔ dzoxɔxɔ dzi akpɔtɔ:

• Ðe nuɖuɖu siwo me nu ʋeʋĩwo le dzi kpɔtɔ alesi nàte ŋui.
• Ne èle kame dem la, tia ɣeyiɣi siwo me yame ƒe dzoxɔxɔ le gota, abe ŋdi kanya alo fiẽ ene.
• Di mɔ nyui siwo dzi nàto aɖu nuteɖeamedzi kple dzimaɖitsitsi dzi. Ðewohĩ ŋugbledede alo yoga akpe ɖe ŋuwò.
• Ne èle tsi ƒum la, zã tsi fafɛ, ke menye tsi dzodzoe o.
• Do awu siwo me mekɔ o, siwo ƒe kpekpeme le bɔbɔe, eye fifia tsia ame me. Avɔwo abe kotoku ene nyo wu.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Kpɔ ɖɔkta ne ède dzesi nu siawo dometɔ aɖe:

• Ne edze abe dɔlékui le ʋuʋudedi alo teƒe siwo le wò ŋutilã ŋu ene (e.g., ne ʋuʋudedi yɔ wo me fũ eye wosea veve ne woka asi wo ŋu).
• Ne ʋuʋudedi kpe ɖe teƒeawo ŋu.
• Ne ʋuʋudedi le wò ŋutigbalẽ ŋu le susu aɖeke si medze o ta.
• Ne èƒoa nu sesĩe akpa be màte ŋu ado dzi o.
• Ne gbɔgbɔ sesẽ na wò alo nèse le ɖokuiwò me be gbɔgbɔtsixe tsi ƒowò.
• Ne èkpɔ dzesi siwo nye `(Anaphylaxis)` (ne esia dzɔ la, ƒo ka na 1990 enumake).

Nukae wòle be mabia nye ɖɔkta?

Ne èyi ɖɔkta gbɔ la, àte ŋu abia nya siawo tɔgbe:

• Nukae ate ŋu anye nusitae dɔléle sia (Cholinergic Urticaria) le ŋunye ɖo?
• Aleke mawɔ aɖe dzoxɔxɔ ƒe ʋuʋu ƒe afɔkua dzi akpɔtɔ?
• Atikewɔwɔmɔnu kae nyo nam wu?

Vovototo kae le ‘Dzoxɔxɔ ƒe Ʋuʋudedi’ kple Cholinergic Urticaria dome?

Dzoxɔxɔ ƒe ʋuʋudedi, si wogayɔna be dzoxɔxɔ si me ʋuʋudedi le alo miliaria, nye ŋutigbalẽ ƒe dɔléle bubu si dzoxɔxɔ hena vɛ. Le nyateƒe me la, enye dzoxɔxɔdɔ ƒomevi aɖe. Edzɔna ne ŋutilãa mete ŋu fa eɖokui nyuie to fifia me o le dzoxɔxɔ kple fafa si nu sẽ ta. Dzoxɔxɔ ƒe ʋuʋu ate ŋu anye dzoxɔxɔ ƒe dɔléle si nu sẽ wu, abe dzoxɔxɔ ƒe ɖeɖiteameŋu alo dzoxɔxɔ ƒe ʋuʋu ene ƒe dzesi.

Cholinergic Urticaria nye dɔléle si nana ame ƒe dzi dzea eme. Gake negbe ɖe wòva nu sẽ abe anaphylaxis ene ko hafi la, zi geɖe la, menye dzoxɔxɔdɔ si nu sẽ wu, abe dzoxɔxɔ ƒe ʋuʋu ene, ƒe dzesi o.

Mlɔeba la, nusi dzi wòle be nàɖo ŋkui! (Gbedasi si Wotsɔ Yi Aƒeme)

Mehiã be Cholinergic Urticaria naxe mɔ na wò be màgawɔ wò gbesiagbedɔwo, kamedede, alo ase vivi na yame ƒe dzoxɔxɔ o. Wò ɖɔkta ate ŋu akpe ɖe ŋuwò nànya nusi gbɔ wò dzesiawo tso. Ne Cholinergic Urticaria le ŋuwò la, atike aɖewo li siwo ate ŋu akpe ɖe ŋuwò. Zi geɖe la, atɔawo nu yina le wo ɖokui si le gaƒoƒo si mede gaƒoƒo ɖeka o me. Ne èle tsitsim la, atɔ siawo ate ŋu ava zu nusiwo dzɔ va yi.

Eyata, sẽ ŋu, xɔ atikewɔlawo ƒe aɖaŋuɖoɖo siwo hiã, eye àte ŋu anɔ agbe nyuie kple nɔnɔme sia!

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