Nukae nye enzymewo? Nukatae wole vevie na míaƒe ŋutilã alea gbegbe ɖo?

Hello! Efɔ̃a? Egbea míele nu ƒom tso nu siwo wɔa dɔ le ɖoɖoezizi me, gake wole vevie ŋutɔ le míaƒe ŋutilã me la ŋu. Woyɔa wo be enzymewo. Ðewohĩ èse ŋkɔ sia kpɔ. Ne menye nenema o la, mehiã o, egbea míaƒo nu tso eŋu bɔbɔe.

Eyata nukawoe nye enzyme siawo? Nukatae míehiã wo?

Kpuie ko la, enzymewo nye protein ƒomevi aɖe . Wole abe robot sue siwo wɔa dɔ le míaƒe ŋutilã me ene. Woƒe dɔ vevitɔe nye be woana atikewo nawɔ dɔ kabakaba le míaƒe ŋutilã me, si nye míaƒe lãmenugbagbeviwo ƒe dɔwɔwɔ . Bu eŋu kpɔ, enzyme siawo kpena ɖe ame ŋu wòwɔa nu aɖewo eye wògblẽa nu aɖewo me. Le nyateƒe me la, enzymewo le nu gbagbewo katã me. Míaƒe ŋutilã wɔa enzymewo le dzɔdzɔme nu. Míekpɔa enzymewo hã tso nuɖuɖu siwo míeɖuna kple esiwo míenona dometɔ aɖewo me, kple tso nusiwo wowɔ dometɔ aɖewo me.

Kpekpeɖeŋu gãtɔ kekeake kae enzymewo naa míaƒe ŋutilã?

Nu vevi siwo enzymewo wɔna dometɔ ɖekae nye kpekpeɖeŋunana le nuɖuɖumeŋusẽ me . Esiae nye alesi nuɖuɖu si míeɖuna la trɔna zua ŋusẽ. Bu eŋu kpɔ, enzyme aɖewo le míaƒe aɖuɖɔ, dɔgbo, dɔgbo, kple dɔgbo me. Esiawoe gblẽa ami, protein, kple carbohydrates siwo míeɖuna la me heɖua wo. Emegbe míaƒe ŋutilã zãa nunyiame siawo hena tsitsi kple lãmenugbagbeviwo ɖɔɖɔɖo. Menye ema ɖeɖeko o, enzymewo kpena ɖe ame ŋu le nu bubu geɖe me. Kpɔe ɖa:

• Be woagbɔ ya ɖekae
• Le lãmeka tutuɖo ta
• Lãmetsiŋusẽ ƒe dɔwɔwɔ
• Aɖiwo ɖeɖeɖa le míaƒe ŋutilã me manya wɔ ne enzyme siawo mele mía si o.

Ðe enzyme ƒomevi geɖe li?

Ẽ, enzyme ƒomevi vovovo akpe geɖe le míaƒe ŋutilã me. Gake nu tɔxɛae nye be dɔ ɖeka koe le enzyme ƒomevi ɖesiaɖe si wòawɔ . Abe alesi safui ɖeka ate ŋu aʋu gaƒoɖokui ɖeka ko ene. Le kpɔɖeŋu me, enzyme si nye Sucrase gblẽa sukli sukli la me. Enzyme si nye Lactase gblẽa sukli lactose si le nyinotsi me la me. Mina míalé ŋku ɖe enzyme ƒomevi vevi aɖewo siwo kpena ɖe mía ŋu zi geɖe be míaɖu nuɖuɖu ŋu:

Nukawoe nye enzyme ƒe akpa aɖewo? Aleke wowɔa dɔe?

Teƒe aɖe le enzyme ɖesiaɖe si woyɔna be ‘teƒe si wɔa dɔ’ . Nɔnɔme tɔxɛ aɖe le teƒe sia si. Míeyɔa nusi enzyme wɔa dɔ ɖe ‘substrate’ dzi . Nɔnɔme tɔxɛ aɖe hã le substrate sia ŋu. Abe gaƒoɖokui kple safui ene. Ele be enzyme la kple substrate la nawɔ ɖeka pɛpɛpɛ hafi woate ŋu awɔ dɔ. Ne wowɔ ɖeka ko hafi atikewo ƒe dɔwɔwɔ ate ŋu adzɔ.

Aleke dzoxɔxɔ kple pH kpɔa ŋusẽ ɖe enzymewo dzii?

Enzymewo hiã nutome ƒe nɔnɔme nyuitɔ hafi woate ŋu awɔ dɔ nyuie. Ne nɔnɔme siawo mesɔ o la, enzymeawo ate ŋu atrɔ woƒe nɔnɔme. Ekema womawɔ ɖeka kple substrate siwo ŋu míeƒo nu tsoe va yi o. Eyata, womawɔ dɔ nyuie o. Enzyme ɖesiaɖe ƒe dzoxɔxɔ kple pH tɔxɛ aɖe le esi si sɔ nyuie wu na:

• pH: Enzymewo sea veve ɖe acid kple alkalinity nu ŋutɔ. Womewɔa dɔ nyuie ne nutoa me nye acid alo alkaline akpa o. Le kpɔɖeŋu me, enzyme si nye pepsin si le míaƒe dɔgbo me gblẽa proteinwo me. Ne acid mesɔ gbɔ ɖe wò dɔgbo me o la, pepsin mate ŋu awɔ dɔ nyuie o.
• Dzoxɔxɔ: Enzyme wɔa dɔ nyuie wu ne wò ŋutilã ƒe dzoxɔxɔ le agbɔsɔsɔ si sɔ me, si ade Celsius 37°C (37°C). Ne dzoxɔxɔa le dzidzim ɖe edzi la, enzyme ƒe dɔwɔwɔ hã dzina ɖe edzi. Gake ne dzoxɔxɔa dzi ɖe edzi akpa la, enzymeawo dzudzɔa dɔwɔwɔ. Esia tae míaƒe ŋutilã ƒe dɔwɔwɔ dzi ɖena kpɔtɔna ne asrã sesẽ aɖe le mía ŋu ɖo.

Dɔléle kawoe enzyme ƒe kuxiwo hena vɛ?

Zi geɖe la, lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe dɔlélewo dzɔna ne enzyme aɖe mesɔ gbɔ o. Woate ŋu atsɔ nusiawo ato domenyiŋusẽfianu (siwo ƒe dome wonyi) tso dzilawo gbɔ ayi ɖeviwo gbɔ. Mina míalé ŋku ɖe domenyiŋusẽfianu ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe dɔléle siwo bɔ dometɔ aɖewo ŋu:

• Fabry dɔléle : Esia nye nɔnɔme si me ŋutilã mete ŋu wɔa enzyme alpha-galactosidase A, si hiã be wòagbã ami o.
• Krabbe dɔléle (globoid cell leukodystrophy): Esia gblẽa nu le enzyme siwo hiã na lãmekawo ƒe lãmenugbagbeviwo ƒe ametakpɔnu , i.e. myelin (Central Nervous System) ŋu.
• Maple syrup urine disease: Esia gblẽa nu le enzyme siwo hiã be woatsɔ agbã kɔsɔkɔsɔ ƒe amino acid aɖewo siwo me alɔdzewo le ŋu .

Tsɔ kpe ɖe esia ŋu la, lãmesẽkuxi bubuwo hã li siwo ate ŋu atso enzyme ƒe masɔmasɔ gbɔ:

• Crohn ƒe dɔléle: Dɔlékui siwo le wò dɔgboa me ƒe masɔmasɔ (gut microbiome ) ate ŋu ana dɔlélenutsiŋutete ƒe dɔwɔwɔ nawɔ dɔ le dɔgboa me. Esia ate ŋu akpɔ ŋusẽ ɖe Crohn ƒe dɔlélea ƒe dzesiwo kple eƒe sesẽ dzi.
• Exocrine pancreatic insufficiency (EPI): Esia nye ɣeyiɣi si me wò dɔgboa mewɔa nuɖuɖumeŋusẽ si sɔ o, si fia be màte ŋu agbã nuɖuɖu nyuie alo axɔ nunyiamewo o.
• Lactose ƒe dɔmawɔmawɔ nyuie : Esia tsoa enzyme si hiã be woatsɔ aɖu lactose, si nye sukli si le notsi kple nyinotsi me la ƒe anyimanɔmanɔ gbɔ.

Ɣekaɣie wòle be nàkpɔ ɖɔkta le enzyme ƒe kuxi aɖe ŋu?

Le nyateƒe me la, manya wɔ be nànyae kple kakaɖedzi nenye be enzyme ƒe kuxi aɖe le ŋuwò ʋudodokpɔ manɔmee o. Gake anyo be nàkpɔ ɖɔkta ne dzesi siwo gbɔna la dometɔ aɖe le ŋuwò:

• Ƒodo ƒe vevesese
• Ʋuʋudedi alo gas ƒe ʋuʋu
• Dɔmetɔtrɔ
• Sese le eɖokui me be ɖeɖi te ye ŋu ŋutɔ (Ðɖiteameŋu) .
• Aɖuɖɔtoe kple ʋuʋudedi
• Kpekpeme dzi ɖeɖe kpɔtɔ si womeɖe o
• Ʋusɔgbɔdɔ
• Ʋu si dona le dɔgboa me