Ènya nu tso Hemophilia C ŋua? Mina míaƒo nu tso nɔnɔme sia si mebɔ o ŋu!

Ɣeaɖewoɣi la, ne wotsoe sue aɖe gɔ̃ hã la, exɔa ɣeyiɣi aɖe hafi ʋu dona, alo? Alo èse be ʋu ƒe dɔléle aɖe le ame aɖe ŋu le wò ƒomea mea? Egbea míele nu ƒom tso ʋumenugbagbeviɣidɔ aɖe si mebɔ vie o, gake ele vevie ŋutɔ be míanya nu tso eŋu. Woyɔa esia be Hemophilia C.

Nukae nye Hemophilia C?

Kpuie ko la, ʋusɔgbɔdɔ C nye ʋusɔgbɔdɔ ƒomevi aɖe si mebɔ kura o. Ʋusɔgbɔdɔ nye dɔléle si me wò ʋu metsina nyuie o, si fia be ne ʋu le dodom la, edzudzɔna vivivi alo medzudzɔna gbeɖe o. Ʋu me protein tɔxɛ aɖe si woyɔna be clotting factor , si woyɔna be Factor XI , si kpena ɖe ʋu ƒe sisi ŋu le amesiwo ŋu ʋusɔgbɔdɔ C le. Wogayɔa esia be Factor XI Deficiency eye woyɔnɛ ɣeaɖewoɣi be Rosenthal syndrome .

Gake zi geɖe la, ʋusɔgbɔdɔ C ƒe dzesiwo nu mesẽna o wu ʋusɔgbɔdɔ ƒomevi bubuawo (A kple B). Gake ʋu ate ŋu ado le amesiwo ŋu ʋusɔgbɔdɔ C le wu alesi wòle le amekoko alo aɖudɔdada me. Ðɔktawo tsɔa ʋumenugbagbeviɣi yeye si wofa tsikpe me, si wotsɔ ʋu si wotsɔ na amewo wɔe la daa esia . Plasma sia kpena ɖe ʋua ŋu wòtsina.

Ðe ʋusɔgbɔdɔ C nye dɔléle si bɔa?

Ao, le nyateƒe me la, esia nye nɔnɔme si mebɔ kura o . Bu eŋu kpɔ, le dukɔ abe Amerika ene me la, ŋutsu kple nyɔnu 100,000 ɖesiaɖe dometɔ ɖeka lɔƒo xɔa ʋusɔgbɔdɔ C. Ne míetsɔe sɔ kple ʋusɔgbɔdɔ ƒomevi bubuwo la, ʋusɔgbɔdɔ A dzea ame abe 12 ene le ŋutsu 100,000 ɖesiaɖe me, eye ʋusɔgbɔdɔ B dzea ame abe 4 ene le ŋutsu 100,000 ɖesiaɖe me. Numekulawo meka ɖe zi nenie ʋusɔgbɔdɔ A alo B gblẽa nu le nyɔnuwo ŋu dzi haɖe o.

Vovototo kawoe le ʋusɔgbɔdɔ A, B, kple C dome?

Ʋusɔgbɔdɔ ƒomevi etɔ̃awo katã nye ʋumenugbagbeviɣidɔ siwo ƒe dome wonyi . Eyae nye be domenyiŋusẽfianu ƒe tɔtrɔ kpɔa ŋusẽ ɖe ʋu ƒe sisi ƒe ɖoɖoa dzi. Gake vovototo sue aɖewo le ƒomevi etɔ̃ siawo dome. Mina míalé ŋku ɖe nusiwo wonye ŋu:

• Hemophilia A kple Hemophilia B dzɔna ne ame nyi domenyiŋusẽfianu si trɔ ƒe dome tso wo dzila ŋutɔŋutɔwo dometɔ ɖeka gbɔ. Gake le ʋusɔgbɔdɔ C me la, woate ŋu anyi domenyiŋusẽfianu si mesɔ o la ƒe dome tso dzila eveawo siaa gbɔ .
• To vovo na amesiwo ŋu ʋusɔgbɔdɔ A alo B le la, zi geɖe la, ʋusɔgbɔdɔ ƒe kuxi siwo gblẽa nu le ƒunukpeƒewo alo lãmekawo ŋu medzea amesiwo ŋu ʋusɔgbɔdɔ C le o . Esia nye vovototo vevi aɖe.
• Zi geɖe la, amesiwo ŋu ʋusɔgbɔdɔ A alo B le ƒe dzesiwo nɔa te ɖe protein siwo naa ʋumenugbagbeviɣidɔ, alo ‘nu siwo naa ʋumenugbagbeviɣidɔ’, ƒe agbɔsɔsɔ le woƒe ʋu me dzi. Le kpɔɖeŋu me, amesi ŋu ʋusɔgbɔdɔ sesẽ A le la akpɔ nu ma ƒe agbɔsɔsɔ si le sue ŋutɔ. Gake nukutɔe la, ate ŋu anye be nu ma ƒe agbɔsɔsɔ si le ame aɖe si ŋu ʋusɔgbɔdɔ C le la mesɔ gbɔ kura o, gake woƒe dzesiwo ate ŋu anɔ bɔbɔe ŋutɔ .
• Ʋusɔgbɔdɔ A kple B ate ŋu adze ameƒomevi kple to vovovo me tɔwo dzi. Gake ʋusɔgbɔdɔ C bɔ vie le Ashkenazi Yudatɔwo ƒe to me tɔwo me . Esia mefia be ame bubu aɖeke mate ŋu atu eŋu o, gake ebɔ ɖe wo dome wu.
• Ʋusɔgbɔdɔ A kple B bɔ ɖe ŋutsuwo me wu nyɔnuwo, gake ʋusɔgbɔdɔ C gblẽa nu le ŋutsuwo kple nyɔnuwo siaa ŋu sɔsɔe .

Nukawoe nye ʋusɔgbɔdɔ C ƒe dzesiwo?

Ame siwo ŋu ʋusɔgbɔdɔ C le ate ŋu akpɔ ʋu si nɔa dodom atraɖii, si womate ŋu atɔ te o le amekoko gã aɖe, abi gã aɖe, alo vidzidzi megbe. Gake womekpɔa ʋu si dona le wo ɖokui si , si nye ɣeyiɣi si me ʋu dzea sisi gɔme le susu aɖeke manɔmee o.

Zi geɖe la, ʋu dona le amesiwo ŋu ʋusɔgbɔdɔ C le la me le mɔ si mesɔ o nu le aɖudɔdada, aɖuɖeɖe, alo aɖuɖɔtoe ɖeɖe vɔ megbe.

Dzesi bubuwo ate ŋu anye:

• Ʋu si dona le ŋɔti me enuenu .
• Abi siwo le ŋutilãa ŋu tso nu suetɔ kekeake gɔ̃ hã gbɔ.
• Ʋu si le aɖuɖɔ me .
• Ʋu si dona fũu akpa le aʋatsotso megbe.
• Vevesese, abi siwo vuvu le amekoko vɔ megbe.
• Le nyɔnuwo gome la, dzinukpɔkpɔ ate ŋu anɔ anyi ŋkeke geɖe, si didi le mɔ si mesɔ o nu.

Nukawoe hea ʋusɔgbɔdɔ C vɛ?

Hemophilia C nye ʋumenugbagbeviɣidɔ si ƒe dome míenyi . Edzɔna ne ʋumenu aɖe si woyɔna be Factor XI , si nye nu 13 siwo nana ʋu sina toa ʋu me si kpena ɖe ame ŋu be ʋu nado blewu alo wòdzudzɔna la dometɔ ɖeka mele asiwò o. Esia le alea elabena F11 domenyiŋusẽfianu si sɔ mele asiwò o .

Zi geɖe la, F11 domenyiŋusẽfianu sia tsɔa mɔfiame siwo ku ɖe Factor XI wɔwɔ ŋu. Ne wotrɔ domenyiŋusẽfianu sia, si fia be ne eva zu nusi mesɔ o la, ʋusɔgbɔdɔ C va doa mo ɖa. Ðewohĩ domenyiŋusẽfianu sia si mesɔ o mawɔ Factor XI wòade edeƒe o, alo ɖewohĩ mawɔe kura o.

Ne dzila ŋutɔŋutɔ eveawo siaa tsɔ domenyiŋusẽfianu si trɔ la na wo vi ko hafi ŋutsuwo kple nyɔnuwo siaa nyia ʋusɔgbɔdɔ C ƒe dome . Ne ame aɖe nyi F11 domenyiŋusẽfianu ɖeka si sɔ kple domenyiŋusẽfianu ɖeka si mesɔ o dome la, ke ʋusɔgbɔdɔ C le ame ma ŋu, gake womeɖea dzesi aɖeke fiana o.

Azɔ, lé ŋku ɖe nusi ate ŋu adzɔ ne dzila siwo si domenyiŋusẽfianu si mebɔ o le la dzi vi ŋu:

• Ðevi siwo dzila siwo ŋu F11 domenyiŋusẽfianu ƒe tɔtrɔ sia le dzi la ƒe mɔnukpɔkpɔ 25% be woaxɔ ʋusɔgbɔdɔ C.
• Vi siwo dzila mawo dzi la ƒe mɔnukpɔkpɔ 50% be woanye dɔlélea tsɔlawo, si fia be domenyiŋusẽfianu si me dɔlélea mele o koe tsɔa wo.
• Mɔnukpɔkpɔ 25% le dzila mawo ƒe viwo si be woanyi F11 domenyiŋusẽfianu si sɔ la dome.

Aleke ɖɔktawo wɔa anya ʋusɔgbɔdɔ C?

Ènya alesi ɖɔktawo dea dzesi ʋusɔgbɔdɔ Ca? Woado wò kpɔ le ŋutilã me gbã . Emegbe woabia wò dzesiwo, abe ŋɔti me ʋu alo ʋu si le dodom le aɖudɔdada vɔ megbe ene ŋu. Woabia wò ƒomea ƒe ŋutinya hã kple nenye be ʋusɔgbɔdɔ alo ʋumenugbagbeviɣidɔ bubu aɖe le ame aɖe ŋu le wò ƒomea me hã . Nyatakaka sia le vevie ŋutɔ le dɔlélea didi me.

Dodokpɔ vevi kawoe wozãna tsɔ ɖoa ​​kpe dɔlélea dzi?

Wò ɖɔkta azã dodokpɔ vevi eve atsɔ aɖo kpe wò dɔlélea dzi:

• Activated partial thromboplastin time test (APTT): Esia nye dodokpɔ si wozãna tsɔ dea dzesi ʋusɔgbɔdɔ. Enaa wò ɖɔkta nyaa ɣeyiɣi didi si wòxɔna hafi wò ʋu natsi .
• Clotting factor test: Ʋudodokpɔ sia ɖea ʋusɔgbɔdɔ ƒomevi kple alesi wòsẽe fiana .

Le go aɖewo me la, wò ɖɔkta ate ŋu abia be woawɔ dodokpɔ ʋɛ aɖewo kpee:

• Ʋu ƒe xexlẽme bliboa (CBC): Dodokpɔ sia dzidzea ʋumenugbagbeviwo hesrɔ̃a wo.
• Prothrombin time (PT) dodokpɔ: Esia hã léa ŋku ɖe alesi wò ʋu ƒoa kabakabae ŋu.
• Fibrinogen dodokpɔ: Ʋudodokpɔ sia dzidzea ʋumenu aɖe si woyɔna be fibrinogen, si kpena ɖe ʋu ŋu be wòatsi la ƒe agbɔsɔsɔme.

Ele vevie be míade dzesii be ʋusɔgbɔdɔ C ate ŋu asesẽ ɣeaɖewoɣi be woakpɔ dɔlélea. Nu ka ta? Ʋudodokpɔ me tsonu, vevietɔ ʋumenugbagbeviɣidɔ ƒe dodokpɔ me tsonu, ate ŋu mawɔ ɖeka kple dɔnɔ aɖe ƒe dzesiwo o. Le kpɔɖeŋu me, ʋumenugbagbeviɣidɔ ƒe dodokpɔ ate ŋu aɖee afia be wò factor ƒe agbɔsɔsɔ le ʋɛ ŋutɔ, gake ɖewohĩ dzesi aɖeke madze le ŋuwò o. Azɔ hã, ʋusɔgbɔdɔ C ƒe dzesiwo ate ŋu anɔ ŋuwò ne wò factor ƒe agbɔsɔsɔme sɔ gɔ̃ hã. Eyata ɖɔktaa abu nusiawo katã ŋu eye wòaƒo nya ta.

Aleke wodaa ʋusɔgbɔdɔ C?

Ðewohĩ mahiã be woawɔ atike na amesiwo ŋu ʋusɔgbɔdɔ C le o vaseɖe esime woawɔ dɔ na wo alo awɔ atike bubu aɖe na wo hafi. Ne ehiã nenema la, ɖɔktawo zãa ‘ʋumenugbagbeviɣi yeye si wofa tsikpe me’, si wotsɔ ʋu si wotsɔ na amewo wɔe.kple atike siwo wotsɔ xea mɔ na ‘nu siwo naa ʋu ƒe sisi’ ƒe gbagbã siwo wona abe atike siwo woatsɔ aɖɔlii ene ƒe ƒuƒoƒo. Ne nyɔnuwo ƒe dzinukpɔkpɔ sesẽna le mɔ si mebɔ o nu, eye wòxɔa ŋkeke geɖe la, ɖɔktawo ate ŋu aŋlɔ fufɔfɔtikewo na wo .

Ðe woate ŋu axe mɔ ɖe ʋusɔgbɔdɔ C nua?

Ao, ʋusɔgbɔdɔ C nye ʋumenugbagbeviɣidɔ si nyi, eyata womate ŋu axe mɔ ɖe enu o . Gake ne dɔlélea le ŋuwò alo wò ƒomea me tɔ aɖe ŋu la, domenyiŋusẽfianu ŋuti aɖaŋuɖoɖo ate ŋu akpe ɖe ŋuwò nàse afɔku si le eme be nàkae na dzidzime siwo gbɔna la gɔme.

Nukae ame si ŋu ʋusɔgbɔdɔ C le ate ŋu akpɔ mɔ na?

Ame akpa gãtɔ siwo ŋu ʋusɔgbɔdɔ C le la ƒe dzesiwo mesẽna o . Ƒã hafi wohea atikewɔwɔ me kuxi sesẽwo vɛ. Ame akpa gãtɔ mekpɔa dzesiawo o vaseɖe esime wova tsi, eye zi geɖe la, dzesi mawo nu mesẽna kura o.

Gake ʋudodo ƒe kuxiwo ate ŋu anɔ ŋuwò le amekoko alo aɖudɔdada vɔ megbe. Ne ʋusɔgbɔdɔ C le ŋuwò la, ele vevie be nàbia wò ɖɔkta tso afɔɖeɖe ɖesiaɖe si wòle be nàwɔ ŋu . Le kpɔɖeŋu me, nana wò ɖɔkta nanya hafi awɔ dɔ na wò eye nàƒo asa na atike aɖewo siwo nana ʋu si dona le ame ŋu dzina ɖe edzi (abe aspirin ene).

Mlɔeba la, nu vevi aɖewo siwo dzi wòle be nàɖo ŋkui

Enyo, eyata, nu ʋɛ aɖewo li siwo dzi wòle be nàɖo ŋkui tso nusiwo ŋu míeƒo nu tsoe me:

• Hemophilia C nye ʋumenugbagbeviɣidɔ si mebɔ kura o .
• Zi geɖe la, eƒe dzesiwo nu mesẽna kura o eye ƒã hafi wòhea lãmesẽkuxi gãwo vɛ.
• Ame geɖe ɖea dzesiwo fiana le woƒe tsitsime ko.
• Gake ʋu ate ŋu ado le ŋuwò wu ame bubuwo le amekoko alo aɖudɔdada me , eyata ele vevie be nàna wò ɖɔkta nanya le nɔnɔme mawo me.
• Ne wokpɔe be ʋusɔgbɔdɔ C le ŋuwò la, mègatsi dzodzodzoe o. Ðo dze kple wò ɖɔkta be nàkpɔ egbɔ be yese nusiwo wòle be nànya kple afɔɖeɖe siwo wòle be nàwɔ gɔme .

Ðo ŋku edzi be atikewɔwɔ ƒe nɔnɔme ɖesiaɖe gɔmesese nyuie nye afɔɖeɖe nyuitɔ kekeake si ana nàkpɔ egbɔ! Menye wò ɖeka koe o, eye atikewɔlawo ƒe aɖaŋuɖoɖo kple kpekpeɖeŋu li na wò ɣesiaɣi.

` Ʋusɔgbɔdɔ C, ʋu ƒe sisi, Factor XI, domenyiŋusẽfianu ƒe dɔléle, ʋudodo, dzesiwo, atikewɔwɔ