Ðewohĩ èse ŋkɔ Hydroxychloroquine le nyadzɔdzɔwo me le COVID dɔvɔ̃a ƒe ɣeyiɣia me. Gake le nyateƒe me la, enye atike xoxo aɖe ŋutɔ si wozãna tso ƒe 1940-awo me. Le gɔmedzedzea me la, ɖɔktawo zãnɛ tsɔ daa asrãdɔ. Egbea la, wozãnɛ wu na atikewɔwɔ ƒe nɔnɔme bubuwo. Egbea, míaƒo nu tso nusi tututu wozãa atike sia na, nugbegblẽ le ame ŋu si wòate ŋu ahe vɛ, kple nusiwo ŋu wòle be míaɖɔ ŋu ɖo ne ele ezãm ŋu.
Ðe atike sia sɔ na Covid-19 nyateƒea?
Esia nye nyabiase si le ame geɖe si. Kpuie ko la, ao . Xexeame ƒe Lãmesẽ Habɔbɔ (WHO) mekafu hydroxychloroquine zazã atsɔ axe mɔ ɖe COVID-19 nu alo adae o. Wova ɖo nyametsotso sia gbɔ le numekuku geɖe wɔwɔ megbe.
Bu eŋu kpɔ ko, numekuku 6 siwo wowɔ le ame akpe geɖe siwo ŋu COVID-19 mele o ŋu la ɖee fia be atike la mekpɔ ŋusẽ aɖeke ɖe mɔxexe ɖe COVID xɔxɔ, kɔdziyiyi, alo ku nu dzi o. Eye numekuku 30 siwo wowɔ le COVID-19 dɔnɔ siwo wu 10,000 ŋu ɖee fia be atike sia meɖe yagbɔgbɔmɔ̃ ƒe hiahiã alo ku ƒe afɔkua dzi kpɔtɔ o. Esia tae womekafui fifia na COVID-19 o.
Eyata dɔléle ka ƒomevie wozãa atike sia na?
Wozãa hydroxychloroquine wu egbea na dɔlélenutsiŋutete ƒe dɔlélewo. Fifia ɖewohĩ èle eŋu bum be nukae nye ema hã.
Kpuie ko la, esiae nye esime míaƒe ŋutilã ŋutɔ ƒe ametakpɔnu, si nye dɔlélenutsiŋutete, dze mía ŋutɔwo ƒe lãmenugbagbevi kple lãkusi siwo le lãmesẽ me dzi vodadatɔe. Esia nana ƒunukpeƒewo, lãmekawo, kple ɣeaɖewoɣi ŋutinu ememetɔwo vuvu eye wògblẽa nu le wo ŋu.
Wò ɖɔkta ate ŋu aŋlɔ atike sia na wò ne dɔléle siawo dometɔ aɖe le ŋuwò:
- Lãmetsiŋusẽ ƒe ƒunukpeƒetetedɔ
- Lãmetsiŋusẽ si woyɔna be lupus erythematosus (SLE) si le lãme na ame .
- Ðeviwo ƒe ƒunukpeƒetetedɔ si nye idiopathic arthritis
- Antiphospholipid ƒe dɔléle
- Sjogren ƒe dɔléle gbãtɔ
Eŋutinunyalawo meka ɖe alesi tututu atike sia wɔa dɔe dzi haɖe o, gake wosusu be etrɔa alesi dɔlélenutsiŋutete ƒe lãmenugbagbeviwo dea dzesi wo nɔewoe. Ate ŋu atsi dɔwɔwɔ siwo hea dɔdzẽ vɛ la dometɔ aɖewo hã.
Nukawoe nye atike sia ƒe nugbegblẽ le ame ŋu?
Abe atike ɖesiaɖe ene la, hydroxychloroquine ate ŋu ahe nugbegblẽ le ame ŋu vɛ. Togbɔ be menye amesiamee xɔa wo o hã la, eƒe nugbegblẽ aɖewo nu mesẽna o eye wo nu yina le ɣeyiɣi aɖe megbe.
| Nusiwo dona tso eme zi geɖe | |
|---|---|
| Xeɖeɖe | Ʋuʋudedi |
| Dɔmetɔtrɔ | Dɔgbo ƒe vevesese |
| Aɖaŋuɖoɖo: Be woaɖe nugbegblẽ le ame ŋu siawo dzi akpɔtɔ la, anyo be nàno atike sia kple nuɖuɖu . | |
Tsɔ kpe ɖe eŋu la, dzesi bubu siwo gbɔna hã ate ŋu ado mo ɖa:
- Ʋuʋudedi alo ʋuʋudedi le ŋutigbalẽa ŋu
- Ŋutilã ƒe viviti dodo alo teƒeteƒewo ƒe dzedzeme
- Taɖa ƒe tɔtrɔ (e.g., amadede ƒe tɔtrɔ) .
- Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ
- Seselelãme trɔna
- Towo ƒe ɖiɖi
Nusiwo wògblẽna le ame ŋu vevie siwo ŋu wòle be nànya nu tsoe
Esiawo nye nya veviwo vie, eyata ele vevie ŋutɔ be nànya esia.
Ŋusẽ si wòkpɔna ɖe dzia dzi
Hydroxychloroquine ate ŋu ahe tɔtrɔ siwo me afɔku le vɛ le dzi ƒe tsotso me. Esia nye nyateƒe vevietɔ ne ènoe kple atike bubu aɖewo abe azithromycin ene . Esia ate ŋu ana dzia ƒe elektrikŋusẽ ƒe dɔwɔwɔ natrɔ. Etɔxɛe la, ate ŋu ana dzi ƒe tsotso kabakaba le mɔ si mesɔ o nu (ventricular tachycardia) alo dzi ƒe tsotso ƒe tɔtrɔ si me afɔku le (QT dometsotso didi).
Ŋku ƒe gbegblẽ
Esia nye nya vevi aɖe ŋutɔ. Togbɔ be mebɔ o hã la, hydroxychloroquine ate ŋu agblẽ nu le ŋku ƒe ŋkume.
Mègaŋlɔ be o be atike sia ate ŋu agblẽ nu le wò ŋkuwo ŋu. Le go aɖewo me la, wò ŋku ate ŋu abu tegbee gɔ̃ hã.
Afɔku sia dzina ɖe edzi le amewo abe:
- Le amesiwo xɔ wu ƒe 60 gome
- Le amesiwo noa atike la ƒe agbɔsɔsɔ gbogbotɔ ƒe 5 kple edzivɔ gome
- Le amesiwo ŋu ayiku alo aklãdɔ sesẽ le gome
- Le amesiwo ŋu ŋku alo ŋkume ƒe dɔléle le xoxo gome
Eyata ne èzã atike sia ɣeyiɣi didi la, ele vevie be ŋkudɔdala nado wò ŋkuwo kpɔ edziedzi.Wò ɖɔkta agblɔ na wò be nàdo wò ŋkuwo kpɔ zi ɖeka le ƒea me alo zi ɖeka ya teti le ƒe 5 ɖesiaɖe me.
Nusiwo gblẽa nu le ame ŋu vevie bubuwo
- Ʋumenugbagbeviɣidɔ: Ƒã hafi ʋusɔgbɔdɔ ate ŋu adzɔ, vevietɔ le amesiwo ŋu ʋumenugbagbeviɣidɔ abe G6PD ƒe anyimanɔmanɔ alo porphyria ene le gome.
- Ayiku me kuxiwo
- Aklã ƒe gbegblẽ alo eƒe dɔmawɔmawɔ nyuie
Atikewo ƒe Nuwɔwɔ Kple Wo Nɔewo
Hydroxychloroquine ate ŋu awɔ dɔ kple atike aɖewo. Ate ŋu atrɔ alesi wowɔa dɔ nyuie alo ana afɔku si le wo ŋu be woagagblẽ nu le wo ŋu nadzi ɖe edzi. Eyata ele vevie be nàgblɔ atike, vitamin, alo kpeɖeŋutɔ ɖesiaɖe si nèzãna na wò ɖɔkta.
| Atike ƒomevi | Nusiwo ŋu wòle be woabu |
|---|---|
| Atike siwo mele be woano ɖekae gbeɖe o | Cisapride, Dronedarone, Pimozide, Thioridazine ƒe atike |
| Atike siwo ate ŋu ahe nugbegblẽ le ame ŋu vɛ | Digoxin, insulin alo suklidɔtike bubuwo, Mefloquine, asrãtikewo, Methotrexate, Cyclosporine |
| Atike siwo ate ŋu ahe nugbegblẽ le ame ŋu bubuwo vɛ | Praziquantel, Atike siwo tsia acid nu, Kaolin, Cimetidine, Ampicillin |
Ne èle tamoxifen nom na no me dɔdzẽ la, ƒo nu tso ema hã ŋu na wò ɖɔkta. Ðewohĩ masɔ be woano atike eve siawo ɖekae wu ɣleti 6 o.
Amekae ate ŋu ano atike sia? Amekae mate ŋui o?
Hydroxychloroquine mele dedie na ame tsitsi kple ɖevi akpa gãtɔ o. Wò ɖɔkta anɔ te ɖe wò kpekpeme dzi anya agbɔsɔsɔme si sɔ.
Togbɔ be numekukuwo ɖee fia be atike sia nono le dedie le fufɔfɔ alo no nana me hã la, .Kpɔ egbɔ be yeƒo nu kple yeƒe ɖɔkta tso atike ɖesiaɖe si nàno ŋu.
Ne psoriasis , si nye ŋutigbalẽdɔléle aɖe le ŋuwò la, kpɔ nyuie le ema ŋu elabena atike sia ate ŋu ana wò dzesiwo nagagblẽ ɖe edzi.
Amekae mele be wòano atike sia o?
Ne atike bubu siwo me 4-aminoquinoline ƒe atikewo le, abe chloroquine ene, melɔ̃a nu le ŋuwò o la, mele be nàno hydroxychloroquine o.
Ne èkpɔ nulɔdɔ ƒe dzesiwo la, yi kɔdzi ƒe dɔwɔƒe si te ɖe ŋuwò kpata (ETU) enumake. Dzesi mawo dometɔ aɖewoe nye:
- Kɔ, nu, alo mo ƒe vuvu
- Ŋutilã ƒe ʋuʋudedi alo ʋuʋudedi
- Ʋuʋudedi sesẽ
Gbedasi si Wotsɔ Yi Aƒeme
- Hydroxychloroquine nye atike si wozãna koŋ tsɔ daa dɔléle siwo dɔlélenutsiŋutete wɔna abe ƒunukpeƒetetedɔ kple lupus ene. Womekafui na COVID-19 o.
- Atike sia ate ŋu agblẽ nu le dzi kple vevietɔ ŋku ŋu vevie.
- Ne èle atike sia nom ɣeyiɣi didi la, ele vevie be nàdo ŋku kpɔ edziedzi abe alesi wò ɖɔkta ɖo aɖaŋu na wò ene.
- Na wò ɖɔkta nanya nu tso atike bubu siwo katã nèzãna ŋu.
- Mègadze atike sia zazã gɔme alo adzudzɔ enono gbeɖe atikewɔlawo ƒe aɖaŋuɖoɖo manɔmee o.
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