Ðe phosphate sɔ gbɔ ɖe wò ŋutilã mea? Mina míaƒo nu tso hyperphosphatemia ŋu!

Èbu nusita ɣeaɖewoɣi nu aɖewo le míaƒe ŋutilã me kɔkɔna wu alesi wòle be woanɔ ŋu kpɔa? Ðewohĩ ɖɔkta aɖe gblɔ na wò be phosphate sɔ gbɔ ɖe wò ʋu me akpa. Alo ɖewohĩ èse eŋu nya le afi aɖe kpɔ. Esiae nye nusi míeyɔna be hyperphosphatemia. Togbɔ be ŋkɔa aɖi nusi wɔ nuku vie hã la, ne míese egɔme nyuie la, menye nusi ŋu míatsi dzi ɖo o.

Nuka tututue nye hyperphosphatemia?

Kpuie ko la, hyperphosphatemia nye ne mineral si woyɔna be phosphate sɔ gbɔ ɖe wò ʋu me. Phosphate nye nunyiame vevi aɖe na míaƒe ŋutilã. Ekpena ɖe mía ŋu be míaƒe ƒuwo kple aɖuwo sẽna, enaa ŋusẽ míaƒe lãmenugbagbeviwo, eye wòkpena ɖe mía ŋu míewɔa lãmenugbagbeviwo ƒe lãkusiwo.

Bu eŋu kpɔ ale, phosphate le abe batri sue aɖe si le míaƒe ŋutilã me ene. Be nusiawo nate ŋu awɔ dɔ nyuie la, ele be elektrikŋusẽ nanɔ wo ŋu. Phosphate nye elektrikŋusẽnamɔ̃ mawo dometɔ ɖeka . Elektrikŋusẽwo nye tomenu siwo ate ŋu axɔ elektrikŋusẽ nyui (+) alo vɔ̃ (-) ne wotsɔ wo ƒo ɖe tsi alo tsi abe míaƒe ʋu ene me. Eyata phosphate ƒe agbɔsɔsɔ sia ƒe dadasɔ le vevie na dɔ geɖe wɔwɔ le ŋutilãa me. Èse egɔmea?

Amekawoe ate ŋu axɔ nɔnɔme sia wu?

Le nyateƒe me la, amesiame ate ŋu axɔ dɔléle sia si woyɔna be hyperphosphatemia. Gake ebɔ ɖe amesiwo ŋu ayiku me kuxiwo le me wu. Etɔxɛe la, amesiwo ŋu ayikudɔléle si nɔa anyi didi (CKD) , vevietɔ amesiwo ŋu dɔléle si de ŋgɔ le, alo amesiwo ƒe ayiku mewɔa dɔ nyuie o, ate ŋu axɔ nɔnɔme sia.

Fifia, nanewo li siwo ate ŋu ana ayikudɔ nadze ame dzi. Ne nusiwo gbɔna dometɔ ɖeka alo esi wu nenema le ŋuwò la, ke ayikudɔléle ate ŋu adze dziwò vie eye to edzi la, àxɔ hyperphosphatemia:

• Ne suklidɔ le ŋuwò (Suklidɔ) .
• Ne ʋusɔgbɔdɔ (ʋusɔgbɔdɔ) le ŋuwò .
• Ne dzidɔ le ŋuwò la .
• Ne ayikudɔ dze ame aɖe dzi le wò ƒomea me (si fia be ate ŋu anye domenyiŋusẽfianu).
• Ne nane si mesɔ o le wò ayikuwo ƒe wɔwɔme me.
• Ne ènye Afrika-Amerikatɔ, Hispaniatɔ, Asiatɔ, alo Amerikatɔ Gbãtɔwo ƒe dzidzimevi (ame siwo le to siawo me ate ŋu axɔ ayikudɔ wu).
• Ne èxɔ wu ƒe 60 la .
• Ne èzãa vevesesenutsitikewo enuenu ɣeyiɣi didi aɖe la , vevietɔ atike siwo me steroid mele o (NSAIDs), siwo woate ŋu aƒle le atikedzraƒe le atikedzraƒe.

Aleke gbegbee nɔnɔme sia bɔe?

Ne èlé ŋku ɖe ame akpa gãtɔ ŋu le xexeame la, ƒã ŋutɔ be hyperphosphatemia ɖeɖeko naxɔ ame. Ema fia be phosphate ƒe dzidziɖedzi le ʋua me ko. Gake, abe alesi megblɔe va yi ene la, ne ayikudɔléle si nɔa anyi didi le ŋuwò , vevietɔ ne esẽ ŋutɔ la, nɔnɔme sia bɔ ŋutɔ. Ne míagblɔe kpuie la, wokpɔe be amesiwo ŋu ayikudɔ sesẽ si nɔa anyi didi le la dometɔ siwo ade 70% xɔ hyperphosphatemia.

Nukae dzɔna ɖe ŋutilãa dzi ne phosphate ƒe agbɔsɔsɔ dzi ɖe edzi?

Míeƒo nu tso alesi phosphate kpena ɖe mía ŋu míedoa ŋusẽ míaƒe ƒuwo kple aɖuwo, naa ŋusẽ lãmenugbagbeviwo, eye wòkpena ɖe mía ŋu míetua lãmenugbagbeviwo ƒe lãkusiwoe ŋu va yi. Nyateƒee. Gake abe nusianu ene la, eƒe agbɔsɔsɔ fũ ate ŋu ahe kuxiwo vɛ.

Bu eŋu kpɔ, ne phosphate ƒe agbɔsɔsɔ si le wò ʋu me dzi ɖe edzi akpa la, edzea calcium ɖeɖe tso wò ƒuwo me gɔme. Nukae dzɔna ɣemaɣi? Ƒuawo gbɔdzɔna eye wogbãna.

Menye ema ɖeɖeko o, ke phosphate si sɔ gbɔ alea ate ŋu ana calcium naƒo ɖe wò ŋkuwo, lãkusiwo, dzitodzitowo, kple ʋukawo me. Esia nye afɔku vie. Elabena le ɣeyiɣi aɖe megbe la, nu siawo siwo woda ɖe eme la dzia dzidɔ, ʋusɔgbɔdɔ , kple ku gɔ̃ hã ƒe afɔku ɖe edzi.

Nukae nye Hyperphosphatemia ƒe dzesiwo?

Zi geɖe la, ne hyperphosphatemia koe le ŋuwò la, mèkpɔa dzesi gã aɖeke o. Ema fia be ɖewohĩ màkpɔe le gɔmedzedzea me be phosphate sɔ gbɔ ɖe yeƒe ŋutilã me akpa o. Gake abe alesi míedzro eme ene la, ne phosphate sia dzi ɖe edzi la, ate ŋu ana calcium nabu le wò ƒuwo kple ʋu me. Woyɔa ema be hypocalcemia . Ema fia be calcium ƒe agbɔsɔsɔ si le ʋua me dzi aɖe akpɔtɔ.

Eyata zi geɖe la, hyperphosphatemia ƒe dzesiwo sɔ kple esiwo hypocalcemia hena vɛ. Kpɔe ɖa be esiawo ɖi nusiwo nènya nyuie hã:

• Lãmetsiwo ƒe ʋuʋu.
• Aɖabɛ siwo le gbagbãm.
• Ŋutilã si ƒu.
• Taɖa ƒuƒui wu wò ɖa si sɔ.
• Ŋkuɖodzinu ƒe kuxiwo .
• Dzikudodo.
• Nuyiwo, aɖe, asibidɛwo, kple/alo afɔwo ƒe ʋuʋu.
• Ɣeaɖewoɣi la, eva abe aɖuɖɔtoe (alɔ̃madɔmadɔ) ene.
• Dzi ƒe tsotso ƒe masɔmasɔ, si nye dzi ƒe tsotso ƒe dɔmawɔmawɔ nyuie.

Nukatae hyperphosphatemia dzɔna?

Susu geɖe ate ŋu anɔ esia ta. Wo dometɔ vevitɔwoe nye:

• Ayikudɔléle si nɔa anyi didi si de ŋgɔ. Esiae nye nusi gbɔ wòtsona wu. Ne ayikuawo mele dɔ wɔm nyuie o la, womete ŋu ɖea phosphate si sɔ gbɔ ɖe ŋutilãa me o.
• Hypoparathyroid ƒe dɔléle si nye Hypoparathyroidism. Esia nye nɔnɔme si me parathyroid lãkusiwo mewɔa parathyroid lãmetsi sue aɖe akpa, si kpɔa calcium kple phosphate ƒe agbɔsɔsɔ si le ŋutilãa me dzi.
• Wò ʋu ƒe pH bɔbɔ wu alesi wòle dzɔdzɔmee (si fia be wò ʋu me acid sɔ gbɔ ɖo). Esia ate ŋu atso esi wò lãkusiwo mete ŋu ɖea ya si woyɔna be carbon dioxide siwo katã dona le wò ŋutilã me ɖa o. Woyɔa esia be gbɔgbɔtsixe ƒe acidosis .
• Ʋu ƒe pH dzi ɖeɖe kpɔtɔ le nu bubuwo ta ( metabolic acidosis ).

Tsɔ kpe ɖe esiawo ŋu la, togbɔ be mebɔ o hã la, hyperphosphatemia hã ate ŋu adzɔ le nusiwo gbɔna ta:

• Ketoacidosis si do ƒome kple suklidɔ.
• Lãmetsiwo ƒe gbegblẽ ( rhabdomyolysis ).
• Dɔlékui sesẽ ( sepsis ).
• Crush injury (abi siwo tso nu kpekpe aɖe si ge ɖe ŋutilãa dzi alo nane si te ɖe ŋutilãa ŋu ɣeyiɣi didi aɖe ta).
• Wò ŋutilã mewɔa nu nyuie ɖe parathyroid hormone ( pseudohypoparathyroidism ) ŋu o.
• Phosphate geɖe ƒe gege ɖe wò ŋutilã me, tso nuɖuɖu si nèɖuna me alo to enema dzi .

Nukae nye nusi gbɔ wòtsona wu?

Abe alesi megblɔe va yi ene la, nusi koŋ gbɔ hyperphosphatemia tsona eye wòbɔ wue nye ayikudɔléle si nɔa anyi didi si de ŋgɔ.

Ðe esia nye dɔléle si xɔa ame mea?

Ao, hyperphosphatemia menye dɔléle si xɔa ame me o. Màte ŋu akakae na ame bubuwo o. Gake ƒã ŋutɔ la, ate ŋu aƒu du le ƒomewo me le domenyiŋusẽfianu ta.

Aleke ɖɔktawo dea dzesi esia?

Ðɔkta ate ŋu anya ne hyperphosphatemia le ŋuwò. Axɔ wò atikewɔwɔ ŋutinya , ado wò ŋutilã kpɔ , eye wòabia wò dzesiwo, wò nuɖuɖu, kple atike ɖesiaɖe si nàno. Be nànya alesi tututu wò phosphate le la, ahiã be woado wò ʋu kpɔ .

Le ʋudodokpɔ me la, ɖɔkta alo dɔnɔdzikpɔla aɖe ʋu sue aɖe tso ʋuka aɖe si le wò alɔnu me to aŋe sue aɖe (21 gauge, si le sue vie wu togɛ si wozãna edziedzi ƒe nugbɔ) zazã me. Woɖoa ʋu sia ɖe dodokpɔxɔ aɖe be woalé ŋku ɖe phosphate agbɔsɔsɔme si le wò ʋu me ŋu. Ne wò phosphate ƒe agbɔsɔsɔ wu miligram 4.5 le ʋu desilita ɖeka me (4.5 mg/dL) la, ., ema fia be hyperphosphatemia le ŋuwò.

Ne wokpɔ dɔléle sia le ŋuwò la, wò ɖɔkta ate ŋu aɖe gbe be woawɔ dodokpɔ bubuwo atsɔ akpɔ wò ayiku ƒe nɔnɔme. Esiawo ate ŋu anye:

• Ʋudodokpɔ bubuwo.
• Dodokpɔ si wowɔna tsɔ léa ŋku ɖe protein si le aɖuɖɔ me ŋu.
• Ultrasound ƒe fotoɖeɖefia.
• MRI- dɔdamɔnu aɖe.
• CT- dɔdamɔnu.
• Kidney biopsy ( ayiku ƒe lãkusi sue aɖe tsɔtsɔ doe kpɔ).

Nukawoe nye atike siwo wozãna na esia?

Atikewɔwɔ na hyperphosphatemia nɔ te ɖe nusi le phosphate si le ƒoƒom ɖe wò ʋu me hem vɛ dzi. Nuɖuɖu kple atike aɖewo hã ate ŋu ana phosphate nasɔ gbɔ ɖe lãme na ame. Ne edzɔ alea la, ahiã be nàɖo seɖoƒe na nuɖuɖu alo atike aɖewo ɖuɖu alo adzudzɔ wo ɖuɖu kura. Alo, ɖewohĩ ahiã be nàtrɔ ɖe atike bubu si me phosphate sɔ gbɔ ɖo ŋu.

Nu vevitɔe nye be nàwɔ ɖe ɖɔkta ƒe mɔfiamewo dzi pɛpɛpɛ.

Ðewohĩ wò ɖɔkta aŋlɔ atike siwo aɖe phosphate si wò ŋutilã xɔna dzi akpɔtɔ. Esia fia be phosphate geɖe dona le wò aɖuɖɔ me (aɖuɖɔtoe). Atike siawo dometɔ aɖewoe nye:

• Sevelamer (Sevelamer - RenaGel®) ƒe ʋuƒoƒo.
• Lanthanum (Lanthanum - Fosrenol®) ƒe lãgbalẽ.
• Kalsium acetate (Kalchium acetate - Calphron®) ƒe lãgbalẽ.

Ne wò phosphate ƒe agbɔsɔsɔ sɔ gbɔ le ayiku ƒe dɔmawɔmawɔ nyuie ta la, wò ɖɔkta ate ŋu adze ʋumenugbagbeviɣidɔ gɔme na wò . Dialysis wɔa nusi wòle be wò ayikuwo nawɔ. Eyae nye be eɖea tsi kple gbeɖuɖɔ siwo sɔ gbɔ, siwo dome phosphate hã le, ɖa le wò ʋu me.

Nukawoe nye nuɖuɖu siwo me phosphorus sɔ gbɔ ɖo?

Nuɖuɖu kple nunono geɖewo li siwo me phosphorus sɔ gbɔ ɖo – nusi me phosphate dzɔna tsoe. Ele vevie be nànya nusiawo, vevietɔ ne hyperphosphatemia le ŋuwò.

• Notsi kple nyinotsibabla, abe notsi, cheese siwo ŋu wotrɔ asi le, kple yogurt ene.
• Nunono aɖewo siwo me carbon le (soda pop/fizzy drinks).
• Lã siwo ŋu wotrɔ asi le ( abe soseti kple bacon ene).
• Nuɖuɖu siwo woɖana kabakaba.
• Nuɖuɖu viviwo ( nusiwo wobla ɖe agba me abe chips, bisiklet ene).
• Nutsetsewo.
• Nuku blibowo , siwo dometɔ aɖewoe nye lu, oats, kple bli (vevietɔ esiwo me bran le).
• Ayi.
• Lãmetsiŋusẽ.

Ðewohĩ wò ɖɔkta gblɔe na wòWoaɖo wò ɖe ayikuŋutinunyala aɖe gbɔ . Ame siawo nye amesiwo bi ɖe alesi nàwɔ akpɔ wò nuɖuɖu dzi be wòado alɔ ayiku ƒe lãmesẽ me. Woakpe ɖe ŋuwò nàwɔ nuɖuɖu ŋuti ɖoɖo tɔxɛ aɖe (ayiku ƒe nuɖuɖu) si axe mɔ ɖe phosphate ƒe agbɔsɔsɔ si le wò ŋutilã me nu.

Ðe mɔ aɖe li si dzi míato asi le nɔnɔme sia nua?

Mɔ nyuitɔ si dzi nàto axe mɔ ɖe hyperphosphatemia nue nye be nàlé be na wò ayiku ƒe lãmesẽ eye nànya phosphate kple calcium agbɔsɔsɔme si nèzãna. Ne èsusu be ate ŋu anɔ afɔku me be yeaxɔ nɔnɔme sia la, ƒo nu kple wò ɖɔkta. Ate ŋu aɖo wò ɖe aɖudɔdala aɖe gbɔ . Aɖuŋutinunyala nye ɖɔkta si bi ɖe nɔnɔme siwo gblẽa nu le ayiku ŋu me.

Ɣeyiɣi kawoe nye nyuitɔ kekeake siwo nàte ŋu ayi ɖɔkta gbɔ?

Ne ènya be hyperphosphatemia le ye ŋu, eye ayikudɔ alo ayiku ƒe dɔmawɔmawɔ nyuie ƒe dzesiwo dze le ŋuwò la, yi ɖɔkta gbɔ enumake. Mègahe ɖe megbe o.

Nya kawoe wòle be nàbia ɖɔkta?

Ne èyi ɖɔkta gbɔ la, ele vevie ŋutɔ be nàbia nya siawo:

• Aleke nàwɔ anya kple kakaɖedzi be hyperphosphatemia le ŋunye?
• Ne dɔléle sia mele ŋunye o la, atikewɔwɔ me dɔléle bubu kawoe ate ŋu anɔ ŋunye?
• Nukae nye ʋu me phosphate ƒe agbɔsɔsɔ si le lãmesẽ me?
• Atike kawoe nèkafu nam?
• Ðe nèhiã atike si woŋlɔ na wò hafi ate ŋu axɔ atike ma, alo ɖe nàte ŋu aƒlee le atikedzraƒea?
• Nuɖuɖu kple nunono kawoe mele be maɖu alo ano o?
• Phosphorus agbɔsɔsɔme kae wòle be maɖu gbesiagbe?
• Àte ŋu aɖom ɖe ayikuŋutinunyala aɖe gbɔa?
• Ðe wòle be makpɔ ayikudɔdala alo eŋutinunyala bibi bubua?

Vovototo kae le Hyperphosphatemia kple Hypocalcemia dome?

Ame eve siawo ate ŋu atɔtɔ ame vie, eyata mina míana eme nakɔ.

Hyperphosphatemia nye ne phosphate ƒe agbɔsɔsɔ si le wò ʋu me sɔ gbɔ akpa .

Hypocalcemia nye ne calcium ƒe agbɔsɔsɔ si le wò ʋu me dzi ɖe kpɔtɔ akpa .

Zi geɖe la, nɔnɔme sia si woyɔna be hypocalcemia dzɔna abe atikewɔwɔ me nɔnɔme bubu aɖe ƒe nugbegblẽ le ame ŋu ene. Hyperphosphatemia nye nusiwo hea hypocalcemia vɛ mawo dometɔ ɖeka.

Gbedasi Mamlɛtɔ si Wotsɔ Yi Aƒeme

Enyo, eyata míeƒo nu geɖe tso hyperphosphatemia ŋu. Kpuie ko la, enye phosphate ƒe agbɔsɔsɔ si le wò ʋu me ƒe dzidziɖedzi. Togbɔ be mebɔ ŋutɔ le ame akpa gãtɔ me le xexeame o hã la, ate ŋu abɔ ŋutɔ le amesiwo ŋu ayikudɔléle si nɔa anyi didi alo ayiku ƒe dɔmawɔmawɔ nyuie le ŋu .

Zi geɖe la, dzesi aɖeke koŋ medzena le gɔmedzedzea me o. Eyata ne dzesi bubuwo dze, ɖewohĩ abe hypocalcemia ene, ko hafi ame geɖe kpɔnɛ be dɔlélea le yewo ŋu.

Ne èva nya be hyperphosphatemia le ye ŋu, vevietɔ ne wogblɔ na wò be ehiã be woaɖe ʋu na wò la, esɔ be nàtsi dzimaɖi ahavɔ̃. Naneke megblẽ le seselelãme mawo ƒe amesinɔnɔ ŋu o. Ƒo nu kple wò ɖɔkta tso nyabiase alo nu siwo ŋu nètsi dzi ɖo ŋu. Woaɖo wò biabiawo ŋu, ana kpekpeɖeŋu si nèhiã la wò, eye woaɖo aɖaŋu na wò le alesi nàwɔ anɔ te ɖe nɔnɔme sia nu nyuie wu ŋu. Ðo ŋku edzi be menye wò ɖeka koe o!

` Hyperphosphatemia, Phosphate, Ayikudɔ, Ayikudɔléle si nɔa anyi didi, Hypocalcemia, Dialysis