Ðewohĩ àyi ɖɔkta gbɔ ne asrã, kɔdzidɔ, alo dɔlékui bubu aɖe le ŋuwò eye wona dɔlékuiwutike wò, alo? Woyɔa dɔlékuiwutike siawo ƒe hatsotso tɔxɛ ɖeka be ‘Macrolides’. Ðewohĩ wona atike aɖe si ŋkɔ sia le wò do ŋgɔ. Eyata egbea, mina míaƒo nu tso nusiwo nye macrolides siawo, dɔléle siwo wozãna tsɔ daa dɔe, kple nusiwo ŋu wòle be míanɔ ŋudzɔ ɖo ne míele wo zãm ŋu.
Nukae nye macrolide siawo?
Kpuie ko la, macrolides nye dɔlékuiwutikewo ƒe hatsotso aɖe. Woƒe dɔ vevitɔe nye be woatɔ te dɔlékui siwo ge ɖe míaƒe ŋutilã me ƒe tsitsi . Ne míagblɔe tututu la, atike siawo wɔa dɔ to mɔxexe ɖe dɔlékuiwo ƒe dɔwɔwɔ nu ale be womate ŋu akaka alo atsi ɖe edzi o.
Gake nu vevi aɖe li si gɔme wòle be mí katã míase le afisia. Dɔlékuiwutike siwo nye macrolide wɔa dɔ ɖe dɔlékuiwo ƒe dɔlékuiwo dzi ko. Womedaa dɔlékuiwo abe dzamezã kple dzamezã ene o.
Azɔ hã, dɔlékuiwutike bubuwo abe penicillin ene ate ŋu anye nulɔdɔ na ame aɖewo. Le nɔnɔme mawo me la, ɖɔktawo ŋlɔa macrolides na ame be wòanye atike bubu.
Nukawoe nye macrolide siwo wozãna wu?
Macrolides ƒomevi vovovowo li siwo ɖɔktawo ŋlɔna na amewo zi geɖe le Sri Lanka kple xexeame godoo. Ðewohĩ ènya ŋkɔ siawo dometɔ ɖeka nyuie.
| Atike Vɔ̃ɖiwo ƒe Ŋkɔ | Ŋgɔdonya kpui aɖe |
|---|---|
| Azithromycin si nye atike si woyɔna be azithromycin | Esia nye macrolide ƒomevi aɖe si ŋu ame geɖe se nu tsoe eye wozãnɛ zi geɖe. |
| Clarithromycin si nye atike si woyɔna be clarithromycin | Wozãnɛ tsɔ daa dɔlékui vovovowo, siwo dometɔ aɖewoe nye dɔlékui siwo hea dɔgbo ƒe abi vɛ. |
| Erythromycin si nye ʋumenugbagbeviɣidɔ | Macrolide ƒomevi xoxo aɖe si va le abe atikekuiwo ene kpakple kreme (gel) si wotsɔ sisi ɖe ŋutigbalẽa ŋu. |
| Fidaxomicin ƒe atike | Wozãnɛ vevietɔ na C. diff dɔlékui, si nye dɔgbowo ƒe dɔléle sesẽ aɖe. |
Nɔnɔme kawo mee wozãa macrolides na?
Wozãa atike siawo tsɔ daa dɔlékuiwo ƒe dɔlékui vovovowo. Kpɔɖeŋu aɖewoe nye esi:
- Aklãdɔ si mebɔ o: Aklãdɔ tɔxɛ aɖe, si woyɔna hã be "aklãdɔ si zɔna."
- Dɔlékuiwo ƒe ŋkume dɔlékuiwo: Dɔlékui siwo hea dzesiwo abe ŋku biã kple tsi ƒe sisi ene vɛ.
- Ŋutilã me dɔlékuiwo: Le nɔnɔmewo abe aklã ene gome la, woŋlɔa gel si me Erythromycin le ɣeaɖewoɣi be wòatsɔ axe mɔ ɖe dɔlékui siwo le ŋutigbalẽa dzi nu.
- Strep throat: Vevietɔ le amesiwo ƒe ŋutilã melɔ̃a penicillin o gome.
- Whooping cough/Pertussis: Dɔlékui si hea kɔdzidɔ sesẽ si nɔa anyi didi vɛ.
- H. pylori dɔlékui: Esia nye dɔlékui aɖe si hea dɔgbo ƒe abi vɛ vevie. Wotsɔa atikewo abe `(Clarithromycin)` kpena ɖe atike bubuwo ŋu daae.
- Dɔlékui siwo woxɔna to gbɔdɔdɔ me: Na dɔlékuiwo abe Chlamydia ene.
- Dɔlékui bubuwo: Wozãa wo hã tsɔ daa dɔlékui siwo tso avu ƒe ƒoƒo (Cat scratch fever), aɖuɖɔtoe, kple mɔzɔla ƒe aɖuɖɔtoe me.
Aleke wozãa atike siawoe eye ɣeyiɣi didi kae wozãna?
Macrolide dɔlékuiwutikewo le ƒomevi vovovowo me.
- Atikekui siwo womi
- Tsi siwo le eme
- Gel alo atike siwo wotsɔ dea ŋutigbalẽa ŋu
- Ami ʋeʋĩwo
- Atike siwo ɖɔkta aɖe nana
Nu vevitɔe nye be nàno atike la abe alesi tututu wò ɖɔkta gblɔ na wò ene, le agbɔsɔsɔ si woŋlɔ na wò me, kple ŋkeke agbɔsɔsɔme si nèŋlɔ nɛ. Vevietɔ ne tsie wònye la, zã dzidzenu si kpe ɖe eŋu la ko. Ne ètsɔ teaspoon dzidze le aƒeme la, mana agbɔsɔsɔme si tututu nàzã o.
Ne èse le ɖokuiwò me be yeƒe lãme sẽ hã la, ele be nàno atike la ŋkeke siwo katã ɖɔktaa ŋlɔ na wò. Ne menye nenema o la, ɖewohĩ womate ŋu ada dɔlélea keŋkeŋ o, eye dɔlékui aɖewo ate ŋu anɔ ŋutilãa me, si ana dɔlélea nagadze egɔme ake. Eyata ele vevie be woawu atikewɔwɔ ƒe nusɔsrɔ̃a nu.
Ðe macrolides ƒe nugbegblẽ le ame ŋua?
Abe dɔlékuiwutike ɖesiaɖe ene la, macrolides ate ŋu ahe nugbegblẽ le ame ŋu suesuesuewo vɛ. Nusi bɔ wue nye dɔgbo ƒe dɔmawɔmawɔ nyuie.
- Aɖuɖɔtoe kple ʋuʋudedi
- Dɔgbo ƒe veve alo vevesese
- Dɔmetɔtrɔ
Zi geɖe la, nugbegblẽ le ame ŋu siawo mesẽna o. Gake woƒe nɔnɔme ate ŋu ato vovo le macrolide ƒomevi si nèzãna nu. Wò ɖɔkta ana nànya nu tso esia ŋu.
Tsɔ kpe ɖe eŋu la, macrolides ate ŋu awɔ dɔ kple atike bubu siwo nèzãna. Eyata kpɔ egbɔ be yegblɔ atike, vitamin, kple kpeɖeŋutɔ siwo katã nèzãna na wò ɖɔkta. Azɔ hã, gblɔe na wò ɖɔkta ne ènoa aha. Ɣeaɖewoɣi la, ahiã be nàƒo asa na ahanono ne èle atike sia nom.
Togbɔ be mebɔ o hã la, ame aɖewo ate ŋu akpɔ nulɔdɔ. Dzesi si bɔ wue nye ŋutigbalẽ ƒe ʋuʋu. Ƒã ŋutɔ hafi ŋutigbalẽ ƒe nɔnɔme sesẽwo abe Stevens-Johnson ƒe dɔléle ene ate ŋu adzɔ.
Ðe dzi ƒe tsotso ƒe tɔtrɔ (arrhythmias) ate ŋu adzɔa?
Esia hã mebɔ kura o, gake ele vevie be nànya. Afɔku sue aɖe koe le macrolide aɖewo ŋu be woahe dzi ƒe tsotso si mesɔ o (arrhythmias) vɛ. Esia le alea elabena atike siawo ate ŋu ana nane si woyɔna be QT dometsotso nadidi ɖe edzi. Kpuie ko la, exɔa ɣeyiɣi didi vie hafi dzia ƒe lãmekaa tena eye emegbe wòɖea dzi ɖi. Esia ate ŋu ahe dzi ƒe tsotso si me afɔku le si woyɔna be Torsades de Pointes vɛ.
Ne dzidɔ le ŋuwò la, ɖɔktaa abu ema ŋu eye wòaŋlɔ dɔlékuiwutike bubu na wò ne ehiã.
Ɣekaɣie wòhiã be nàyi ɖɔkta gbɔ?
Ele vevie ŋutɔ be nàƒo nu kple wò ɖɔkta le nɔnɔme siwo gbɔna me.
| Mɔnukpɔkpɔ | Nuɖᴐɖᴐ |
|---|---|
| Le nɔnɔme sia tɔgbe me la, ƒo nu kple ɖɔktaa. | |
| Nyabiase siwo ku ɖe alesi woano atike ŋu | Ne mènya nu tso nuwo abe agbɔsɔsɔme si woazã kple ɣeyiɣi si woatsɔ awɔe ŋu o. |
| Dzimaɖitsitsi le eƒe nugbegblẽ le ame ŋu ta | Ne esesẽ akpa be woano atike la le nuwo abe ʋuʋudedi kple ʋuʋudedi ene ta. |
| Dzesiwo dzi ɖeɖe kpɔtɔ aɖeke meli o | Ne womeda wò dɔlélea le atikeawo zazã vɔ megbe gɔ̃ hã o. |
| Nulɔdɔ ƒe dzesiwo | Ne nane abe ŋutigbalẽ ƒe ʋuʋudedi ene do. |
| Le nɔnɔme sia tɔgbe me la, yi kɔdzia ƒe Dɔwɔƒe si Kpɔa Dɔléle Kpatawo Gbɔ (ETU) enumake. | |
| Aɖuɖɔtoe sesẽ | Ne tsi ƒe aɖuɖɔtoe le ŋuwò zi geɖe gbesiagbe alo ne tsi vɔ le lãme na wò ƒe dzesiwo. |
| Nulɔdɔ sesẽ | Ne èkpɔ dzesi siwo nye anaphylaxis, abe gbɔgbɔ sesẽ kple mo ƒe vuvu ene la, esia nye nudzɔdzɔ kpata sesẽ aɖe. |
Gbedasi si Wotsɔ Yi Aƒeme
- Macrolides nye dɔlékuiwutike ƒomevi aɖe si wonana tsɔ daa dɔlékuiwo ƒe dɔlélewo . Womewɔa dɔ ɖe dɔlékuiwo ƒe dɔlélewo ŋu abe dzamezã ene o.
- No atike bliboa si wò ɖɔkta ŋlɔ na wò, hena ŋkekeawo katã . Mègadzudzɔ enono le afã me o.
- Na wò ɖɔkta nanya nu tso atike bubu siwo katã zãm nèle kple atikewɔwɔ ƒe nɔnɔme bubu ɖesiaɖe si le ŋuwò (vevietɔ dzidɔ).
- Nuveviwɔame suesuesuewo abe dɔgbo ƒe ʋuʋu ene ate ŋu ado mo ɖa, gake ne aɖuɖɔtoe sesẽ aɖe le ŋuwò, ŋutigbalẽ le ʋuʋum, alo gbɔgbɔ sesẽ na wò la, di atikewɔlawo ƒe aɖaŋuɖoɖo enumake.
- Ne nulɔdɔ ƒe dzesi sesẽwo alo tsikuɖiɖi si hiã be woawɔ atike na wò enumake la, yi kɔdzi si te ɖe ŋuwò ƒe Dɔwɔƒe si Kpɔa Nudzɔdzɔ Kpatawo Gbɔ (ETU) .
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