Èse ŋkɔ ‘Methylene Blue’ kpɔa? Ðewohĩ menye nenemae o. Enye atike si mebɔ kura o gake wòle vevie ŋutɔ. Le eƒe nɔnɔme ŋutɔŋutɔ me la, edzena abe tsi si ƒe amadede nye blɔ goglo ene. Togbɔ be adze abe avɔ ƒe amadede si bɔ ene hã la, ŋusẽ le eŋu be wòada atikewɔwɔ me dɔléle sesẽ geɖe. Mina míalé ŋku ɖe ŋutinya si le megbe na atike blɔ tɔxɛ sia ŋu nyuie.
Nuka tututue nye Methylene Blue?
Kpuie ko la, Methylene Blue nye atike si ɖɔktawo zãna tsɔ daa ʋumenugbagbeviɣidɔ si mebɔ o si woyɔna be methemoglobinemia . Togbɔ be enye atike sesẽ hã la, wodonɛ abe tsi blɔ ene to atike si wodona ɖe wò ʋuka me tẽ me.
Atike sia ƒe ŋutinya wɔ nuku ŋutɔ. Germanytɔ atikeŋutinunyala aɖee ke ɖe eŋu zi gbãtɔ le ƒe alafa 19 lia me. Le gɔmedzedzea me la, wozãnɛ abe amadede ene le avɔlɔ̃ƒewo eye emegbe wozãnɛ abe amadede ene le dodokpɔ siwo wowɔ le nudokpɔƒe me.
Anɔ abe ƒe 125 enye sia la, Germanytɔ atikewɔla aɖe te eŋudɔwɔwɔ tsɔ daa asrãdɔ. Tso ɣemaɣi la, eƒe atikewɔwɔ me zazã va trɔ ŋutɔ. Fifia la, FDA da asi ɖe edzi koŋ na methemoglobinemia dada. Gake ɖɔktawo ate ŋu azãe ɣeaɖewoɣi na dɔdamɔnu bubuwo.
Nɔnɔme kawo mee wozãa atike sia na?
Abe alesi míegblɔe ene la, Methylene Blue zazã vevitɔe nye be woatsɔ ada methemoglobinemia.
Eyata nukae nye methemoglobinemia?
Esia nye dɔléle si do ƒome kple ʋu. Kpuie ko la, ne dɔléle sia le ŋuwò la, wò ʋumenugbagbevi dzĩwo mete ŋu tsɔa ɔksidzin yia wò ŋutilã ƒe lãkusiwo me nyuie o.
Ne oxygen si sɔ mele ŋutilãa me o , teƒewo abe wò nuyiwo, ŋutigbalẽ, aɖe, kple asibidɛwo ene ate ŋu atrɔ zu blɔ. Woyɔa esia be cyanosis . Le vidzĩwo gome la, woyɔa esia ɣeaɖewoɣi be ‘blue baby syndrome’.
Ame aɖewo nyia nɔnɔme sia ƒe dome le domenyiŋusẽfianu me. Gake atike aɖewo zazã, atike siwo ŋu se meɖe mɔ ɖo o zazã, alo atike aɖewo koŋ zazã ta sua ame geɖe si .
Methemoglobinemia ate ŋu anye dɔléle si ate ŋu ade ame ƒe agbe afɔku me . Methylene Blue nye atikewɔmɔnu siwo wɔa dɔ nyuie wu siwo li nɛ la dometɔ ɖeka.
Aleke atike sia wɔa dɔe?
Methylene Blue gena ɖe wò ʋukawo me eye wòtoa atike ƒe dɔwɔwɔ me si trɔa methemoglobin (si mate ŋu atsɔ oxygen o) agbugbɔ azu hemoglobin si le dɔ wɔm (si ate ŋu). Bu eŋu be ‘wòagbugbɔ’ wò ʋu ƒe ɔksidzin tsɔtsɔ yi teƒe bubu.
Ðɔkta alo dɔnɔdzikpɔla naa atike sia le kɔdzi alo atikewɔƒe abe ʋuka me tsi ene. Zi geɖe la, dɔa xɔa abe miniti 5 va ɖo 30 ene. Zi geɖe la, agbɔsɔsɔ ɖeka sɔ gbɔ be wòaɖe dzesiawo dzi akpɔtɔ. Gake ne dzesiawo gakpɔtɔ le gaƒoƒo ɖeka megbe la, wò ɖɔkta ate ŋu atso nya me be yeado atike bubu na wò.
Nusiwo dona tso eme kple atikewo ƒe kadodo ( side effects & Interactions) .
Hafi nàna atike sia la, wò ɖɔkta alé ŋku ɖe wò atikewɔwɔ ŋutinya bliboa ŋu, elabena ate ŋu anye nusi mele dedie na ame ɖekaɖeka siwo ŋu lãmesẽkuxi aɖewo le o.
| G6PD ƒe anyimanɔmanɔ | Esia nye domenyiŋusẽfianu ƒe ʋumenugbagbeviɣidɔ. Ne ame si ŋu dɔléle sia le xɔ Methylene Blue la, ate ŋu ana ʋumenugbagbevi dzĩwo natsrɔ̃ kabakaba (hemolysis) , si ahe atikewɔwɔ kpata sesẽ aɖe vɛ. Esia le vevie ŋutɔ. |
| Fufɔfɔ alo no nana | Ne èfɔ fu, nèle ɖoɖo wɔm be yeafɔ fu, alo nèle no nam la, ele be nàna wò ɖɔkta nanya . |
| Nɔnɔme bubuwo | Taflatse na wò lãmesẽdɔwɔla nanya ne ayiku alo aklãdɔ aɖe le ŋuwò le ŋutinya me. |
| Nusiwo ŋu nulɔdɔ le | Gblɔe na wò ɖɔkta ne Methylene Blue alo atike, nuɖuɖu, alo amadede bubu aɖe ƒe nulɔdɔ le ŋuwò. |
| Cyanide ƒe aɖi | Ne ɖikeke aɖe li be aɖi le cyanide me la, ele be nàna wò ɖɔkta nanya enumake. |
Nukawoe nye eƒe nugbegblẽ le ame ŋu?
Abe atikewo katã ene la, Methylene Blue ate ŋu ahe nugbegblẽ le ame ŋu vɛ.
- Nu suesuesue siwo dona tso eme (zi geɖe la, menye nusi gbɔ wòtsona be woavɔ̃ o):
- Aɖuɖɔ kple aɖuɖɔ ƒe amadede ƒe tɔtrɔ blɔ-amadede (esia sɔ le amadedea ƒe amadede ta).
- Aɖuɖɔtoe kple ʋuʋudedi .
- Ŋutilã ƒe amadede ƒe tɔtrɔ fafɛ.
- Vevesese le afisi wodo atikea le.
- Nusiwo gblẽ le ame ŋu vevie siwo hiã be woakpɔ egbɔ enumake:
- Akɔtave.
- Taɖuame.
- Taɖuame.
- Tɔtɔ.
- Fifia ƒe dzidziɖedzi.
- Ƒodo ƒe vevesese.
Atikewo ƒe Nuwɔwɔ Kple Wo Nɔewo
Esia nye akpa vevi aɖe. Atike aɖewo nono kpe ɖe Methylene Blue ŋu ate ŋu ahe afɔku vɛ.
Vevietɔ, atike aɖewo siwo wozãna na blanuiléle alo dzimaɖitsitsi (abe SSRI ene) ate ŋu ahe nɔnɔme si ate ŋu ade ame ƒe agbe afɔku me si woyɔna be ‘Serotonin Syndrome’ vɛ ne wotsɔe kpe ɖe Methylene Blue ŋu.
Esia dzɔna ne serotonin ƒe agbɔsɔsɔ le wò ahɔhɔ̃ me va sɔ gbɔ akpa, si wɔnɛ be dzesiwo abe ʋuʋudedi, dzoxɔxɔ sesẽ, kple susu ƒe dɔwɔwɔ ene, si ate ŋu awu ame. Le susu sia ta la, ele be nàna wò ɖɔkta nagblɔ atikewo, vitaminwo, kple nuɖuɖu kpeɖeŋutɔ siwo katã nèzãna fifia ƒe ŋkɔ bliboa.
Zãzã bubuwo kple numekukuwo
Togbɔ be methemoglobinemia koe FDA da asi ɖe edzi hã la, ɖɔktawo zãnɛ ɣeaɖewoɣi hena ‘nusiwo womeŋlɔ ɖe edzi o’ le dɔdamɔnu tɔxɛ aɖewo me.
- Dɔlékuiwutike: Wozãnɛ abe atike ene na aɖi si le atikewo me tso nusiwo le abe nitrites ene me. Ne èsusu be atikewo ƒe aɖi le ye ŋu la, yi dɔwɔƒe si te ɖe ŋuwò si kpɔa nudzɔdzɔ kpatawo gbɔ enumake.
- Dzidziƒoame: Wozãnɛ tsɔ daa dzidziƒoame sesẽwo le dɔnɔdzikpɔƒe siwo wokpɔa dɔnɔwo gbɔ vevie (ICU).
- Kansa ƒe dzesidede:Wozãnɛ abe amadede ene le kansa ƒe amekoko me tsɔ dea dzesi kansa ƒe lãmenugbagbeviwo kple ʋuka siwo me ʋu sina tona.
- Sidzedze ŋuti numekuku: Wole numekuku wɔm be woakpɔe ɖa be ate ŋu aɖe vi na nɔnɔmewo abe Alzheimer dɔléle ene hã.
- Dɔlékuiwutike: Numekuku aɖewo ɖee fia be ne kekeli wɔ dɔ na Methylene Blue la, ate ŋu akpe ɖe ame ŋu wòatsrɔ̃ dɔlékui kple dɔlékui aɖewo.
Vevietɔ: Dɔwɔwɔ siawo ƒe akpa gãtɔ gakpɔtɔ le numekuku ƒe akpaa me. Mègate kpɔ be yeazã atike sia le nyatakaka siwo le Internet dzi nu o. Wɔ ɖe wò ɖɔkta ƒe mɔfiamewo dzi ɣesiaɣi.
Gbedasi si Wotsɔ Yi Aƒeme
- Methylene Blue nye atike tɔxɛ aɖe si wozãna na ʋu ƒe dɔléle si mebɔ o gake wòsẽa ŋu, si nye methemoglobinemia.
- Mègazã atike sia le ɖokuiwò si gbeɖe o. Ele be woadoe ɖe ʋuka me ɣesiaɣi le atikewɔla alo dɔnɔdzikpɔla ƒe dzikpɔkpɔ te le atikewɔƒe.
- Ne G6PD ƒe gbɔdzɔgbɔdzɔ le ŋuwò la, ele vevie ŋutɔ be nàna wò ɖɔkta nanya, elabena esia le vevie ŋutɔ na wò dedienɔnɔ.
- Na wò ɖɔkta nanya nu tso atike bubu siwo katã nèzãna (vevietɔ blanuilélenutsitikewo) ŋu be nàƒo asa na Serotonin Dɔléle ƒe afɔkua.
- Aɖuɖɔ si ƒe amadede nye blɔ nye atike la ƒe nugbegblẽ le ame ŋu si sɔ; mègatsi dzodzodzoe o. Gake di atikewɔlawo ƒe kpekpeɖeŋu enumake ne akɔta le veve sem alo tɔtɔ wò.
- Atike sia zazã bubu siwo woate ŋu azã la gakpɔtɔ nye dodokpɔ. Ðo ŋu ɖe wò ɖɔkta ƒe atikewɔwɔ ŋuti aɖaŋuɖoɖowo ŋu vevie ɣesiaɣi.
Methylene Blue, Methemoglobinemia, Cyanosis, G6PD ƒe anyimanɔmanɔ, Serotonin Dɔléle, Atikewo ƒe nugbegblẽ le ame ŋu
