Èse nya G6PD ŋkɔ kpɔa? Ðewohĩ ɖɔkta aɖe gblɔe na wò, alo ɖewohĩ wò ƒomea me tɔ aɖe gblɔe. Alo ɖewohĩ enye nu yeye kura na wò. Ke hã, mègavɔ̃ ne èse ŋkɔa o. G6PD ƒe anyimanɔmanɔ nye domenyiŋusẽfianu ƒe dɔléle si bɔ ŋutɔ si dzea ame siwo ade miliɔn 400 dzi le xexeame katã. Eɖi tɔtrɔ sue aɖe le míaƒe ŋutilã me wu dɔléle. Eyata mina míaƒo nu tso wo katã ŋu bɔbɔe ŋutɔ eye le xɔlɔ̃wɔwɔ me egbea.
Nuka tututue nye G6PD ƒe anyimanɔmanɔ?
Enyo, mina míagblɔ nya sia kpuie. Lãmenugbagbevi ƒomevi aɖe si woyɔna be ʋumenugbagbevi dzĩwo le míaƒe ʋu me . Lãmenugbagbevi siawo tsɔa ɔksidzin yia míaƒe ŋutilã katã me. Ele abe ʋu si tsɔa adzɔnuwo yia aƒe aɖe me ene.
Fifia, enzyme tɔxɛ aɖe li si kpena ɖe ʋumenugbagbevi dzĩ siawo ŋu be woanɔ lãmesẽ me eye ŋusẽ nanɔ wo ŋu. Míeyɔa esia be `Glucose-6-Phosphate Dehydrogenase`, alo G6PD kpuie. Bu enzyme sia be enye ʋumenugbagbevi dzĩwo takpɔla, alo `ŋusẽnamɔ̃' si naa ŋusẽ wo. G6PD enzyme sia kpɔa ʋumenugbagbevi dzĩwo ta tso nu gbegblẽ siwo le ʋua me dometɔ aɖewo me.
Nusi dzɔna le amesi ŋu G6PD mele o ƒe ŋutilã me enye be womewɔa G6PD enzyme la le agbɔsɔsɔ si sɔ me o. Alo enzyme si wowɔ la mewɔa dɔ nyuie o. Esia nye domenyiŋusẽfianu . Ema fia be ènyi esia ƒe dome tso dawò alo fofowò gbɔ, eye menye dɔléle si xɔa ame me o.
Zi geɖe la, G6PD ƒe anyimanɔmanɔ menye kuxi gã aɖeke o. Gake ne èno atike aɖewo, atike aɖewo, alo nuɖuɖu aɖewo (vevietɔ gbe ƒomevi aɖewo) la, ʋumenugbagbevi dzĩawo dzea gbegblẽ gɔme elabena ametakpɔnu ma bu. Esiae nye nusi míeyɔna be `hemolytic anemia.` Mina míagalé ŋku ɖe eŋu vie.
Nukawoe nye dzesiawo? Aleke míewɔna dea dzesi esia?
Nusi wɔ nuku le afisiae nye be ame geɖe siwo ŋu G6PD ƒe anyimanɔmanɔ meɖea dzesi aɖeke fiana o . Wonɔa agbe si sɔ. Ne wodo go ‘nu siwo ʋãa ame’ siwo míeyɔ va yi la dometɔ ɖeka, si nye atike alo nuɖuɖu gbegblẽ aɖe ko hafi kuxia doa mo ɖa.
Gake ɣeaɖewoɣi la, vidzĩ ate ŋu axɔ jaundice (ŋuti ƒe ɣie) le edzidzi megbe, eye zi geɖe la, woate ŋu adae bɔbɔe.
Ne amesi ŋu G6PD ƒe anyimanɔmanɔ do go nane si gblẽa nu le ame ŋu la, ate ŋu axɔ nɔnɔme aɖe si woyɔna be `hemolytic anemia.` Kpuie ko la, ɣeyiɣi sia mee ʋumenugbagbevi dzĩwo gblẽna eye wogblẽna kabakaba wu alesi woate ŋu awɔe. Ʋumenugbagbevi dzĩwoe tsɔa ɔksidzin ƒoa xlã ŋutilãa. Eyata ne wogblẽ wo la, ŋutilãa ƒe ŋutinuwo mekpɔa ɔksidzin si wohiã o.
Ne nɔnɔme sia si nye `hemolytic anemia` dzɔ la, ate ŋu anye nu sesẽ ŋutɔ. Eyata ele vevie ŋutɔ be nànya dzesi siawo.
Tabla si le ete la yɔ ʋusɔgbɔdɔ ƒe dzesi siwo bɔ.
| Dzesi si dzena | Nuɖᴐɖᴐ |
|---|---|
| Ŋutilã si ƒe ŋutigbalẽ le ɣie | Ŋutilãa ƒe amadede trɔna eye wòbiãna, abe ɖe ʋu mele ŋutilãa me o ene. |
| Ŋutilã kple ŋku ƒe ɣie (Jaundice) . | Bilirubin, si nye nusi dona ne ʋumenugbagbevi dzĩwo gblẽ, nana ŋku ƒe ŋutigbalẽ kple ŋku ɣiwo zua ɣie. |
| Aɖuɖɔ doviviti | Aɖuɖɔa trɔna zua aŋutiɖiɖi alo cola. |
| Asrã | Àte ŋu ase le ɖokuiwò me be asrã le ye ŋu le susu aɖeke manɔmee. |
| Ðeɖiteameŋu kple gbɔdzɔgbɔdzɔ | Sese le eɖokui me be agbe mele ye ŋu o, gbɔgbɔtsixe tsi ƒonye, eye ɖeɖi te ye ŋu vevie. |
| Nu ƒe susu ƒe tɔtɔ | Ne ahɔhɔ̃a mekpɔ oxygen si sɔ o la, àte ŋu atɔtɔ eye yeƒe susu natsi. |
| Dzi ƒe tsotso | Dzi ƒe tsotso dzina ɖe edzi. |
Ne dzesi siawo nu sẽ eye wonɔa anyi ɖaa la, ele be nàyi ɖɔkta gbɔ enumake . Ɣeaɖewoɣi la, ahiã be nàyi kɔdzi ƒe Dɔwɔƒe si Kpɔa Nudzɔdzɔ Kpatawo Gbɔ (ETU).Ðewohĩ ahiã hã be woaɖee ɖa. Gake zi geɖe la, ne wonya ɖe nusi gbɔ nɔnɔme sia tso ko la, ahaya le eɖokui si le abe kwasiɖa eve ene me.
Nuka tae wòle alea ɖo? Amekae ate ŋu axɔe bɔbɔe wu?
Abe alesi míegblɔe va yi ene la, G6PD ƒe anyimanɔmanɔ nye domenyiŋusẽfianu ƒe nɔnɔme keŋkeŋ . Esia fia be ènyie dome tso dziwòlawo gbɔ. Mɔ aɖeke meli si dzi woato axe mɔ ɖe enu o.
Ke hã, ame ƒe ƒuƒoƒo aɖewo ate ŋu axɔ nɔnɔme sia.
- Le ŋutsuwo gome (wu nyɔnuwo).
- Le amesiwo le dukɔ siwo le Afrika, Asia, Titina Ɣedzeƒe, kple Mediterranea-nutowo me gome.
Ne ènya be G6PD ƒe dɔmawɔmawɔ nyuie le wò ƒomea me la, mɔnukpɔkpɔ li be wò hã àte ŋu akpɔe. Eyata anyo be nàƒo nu tso eŋu na wò ɖɔkta.
Aleke nàwɔ anya ne G6PD ƒe dɔmawɔmawɔ nyuie le ŋuwò?
Mɔ bɔbɔe aɖe ŋutɔ li si dzi nàto anya. Ema nye to ʋudodokpɔ wɔwɔ me . Wò ɖɔkta aɖo aɖaŋu le dodokpɔ sia ŋu le wò ƒome ŋutinya kple ne dzesiwo le ŋuwò nu.
Zi geɖe la, wowɔa dodokpɔ si me wodoa ame kpɔna gbã be woakpɔe ɖa be G6PD ƒe anyimanɔmanɔ le eme hã. Ne eɖee fia be gbɔdzɔgbɔdzɔ aɖe li la, wogawɔa dodokpɔ bubuwo be woakpɔ alesi gbegbe wòsẽe. `Beutler dodokpɔ` nye dodokpɔ mawo dometɔ ɖeka.
To dodokpɔ siawo me la, àte ŋu anya nenye be G6PD ƒe gbɔdzɔgbɔdzɔ le ŋuwò eye ne ele nenema la, ekema alesi gbegbe wòle.
Aleke woawɔ anɔ agbe kple G6PD ƒe anyimanɔmanɔ? Nu kawoe wòle be míaƒo asa na?
Esiae nye akpa vevitɔ kekeake. Ne wokpɔe be G6PD ƒe dɔmawɔmawɔ nyuie le ŋuwò la, mehiã be woawɔ atike aɖeke koŋ na wò o . Nusi wòle be nàwɔ koe nye be nàƒo asa na ‘nu siwo ʋãa ame’ siwo gblẽa nu le wò ʋumenugbagbevi dzĩwo ŋu eye wòhea nɔnɔme si woyɔna be hemolytic anemia vɛ.
Ema fia be ele be nàƒo asa na atike, atike, kple nuɖuɖu aɖewo kura. Woyɔa nusiawo be nusiwo hea ‘oxidative stress’ vɛ.
Ðo ŋku kplɔ̃ si le ete dzi. Ele vevie ŋutɔ be nàɖe nusiawo ɖa le wò agbe me.
| Nusiwo wòle be amesiwo ŋu G6PD ƒe anyimanɔmanɔ naƒo asa na godoo | |
|---|---|
| Ƒomevi | Kpɔɖeŋuwo |
| Nuɖuɖu | Fava beans - Esia nye nuɖuɖu vevitɔ kekeake eye afɔku le eme. Le dukɔ aɖewo me la, woyɔa esiawo hã be broad beans. |
| Atikewo | Vevesesenutsitike aɖewo (e.g., aspirin si ƒe agbɔsɔsɔme sɔ gbɔ ) . |
| Dɔlékuiwutike siwo me "Sulf" le (e.g. Sulfonamides) . | |
| Atike siwo tsia asrãdɔ nu siwo me "quine" le. | |
| Atikewo ƒe dɔwɔwɔ | Naphthalene - Esiawo le mothballs siwo woda ɖe awudzraɖoƒewo me. Woƒe ʋeʋẽa gbɔgbɔ gɔ̃ hã gblẽa nu le ame ŋu. |
Vevietɔ: Ne G6PD ƒe dɔmawɔmawɔ nyuie le ŋuwò la, ele be nàgblɔe na wò ɖɔkta ɣesiaɣi si nèkpɔe. Emegbe ne eŋlɔ atike na wò la, atia atike siwo le dedie na wò. Mègano atike aɖeke gbeɖe ne mèyi ɖɔkta gbɔ gbã o.
Gbedasi si Wotsɔ Yi Aƒeme
- G6PD ƒe anyimanɔmanɔ menye dɔléle si wòle be woavɔ̃ na o. Enye domenyiŋusẽfianu ƒe nɔnɔme si le ame geɖe si le xexeame, eye wòtso dzidzime yi dzidzime.
- Dzesi aɖeke mele ame geɖe ŋu o eye ne wodo atike vɔ̃ɖi aɖe, nuɖuɖu (vevietɔ fava-ku), alo atike aɖe ko hafi wodzea dɔ.
- Be nàte ŋu akpɔ wò agbe dzi dzidzedzetɔe la, ele be nànya nu siwo tututu gblẽa nu le ŋuwò eye nànɔ adzɔge tso wo gbɔ.
- Ne èkpɔ dzesiwo abe dzoxɔxɔ, ɖeɖiteameŋu si gbɔ eme, ŋutigbalẽ ƒe ɣie, kple aɖuɖɔ si do viviti ene la, yi ɖɔkta gbɔ enumake.
- Ðo ŋku edzi na wò ɖɔkta ɣesiaɣi si nèkpɔe be G6PD ƒe dɔmawɔmawɔ nyuie le ŋuwò. Ele vevie ŋutɔ na wò dedienɔnɔ.
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