Ède dzesi teƒe aɖe si le dzo dam le viwòa alo wò ŋutɔ wò ŋutilã ŋu kpɔa? Ðewohĩ ɖeko nètsɔ wò asibidɛ ƒo teƒea blewuu, eye kasia teƒea biã, te ʋuʋudedi, eye ʋuʋudedi sue aɖe do ɖe etame. Ne nuteƒekpɔkpɔ sia nye nusi nènya nyuie la, ele vevie ŋutɔ be nànya nɔnɔme si ŋu míele nu ƒom tsoe egbea.
Kpuie ko la, nukae nye Urticaria Pigmentosa?
Urticaria Pigmentosa nye atɔ ƒomevi aɖe si dzɔna ɖe ŋutigbalẽ dzi. Wokpɔnɛ zi geɖe le ɖevi suewo kple sɔhɛ tsitsiwo gome. Le nyateƒe me la, enye nɔnɔme aɖe si woyɔna be `mastocytosis' ƒe ƒomevi aɖe.
Fifia ɖewohĩ èle eŋu bum be nukae nye `mastocytosis` hã. Ele bɔbɔe ŋutɔ. ``mast cells`` nye lãmenugbagbevi ƒomevi tɔxɛ aɖe le míaƒe ŋutilã ƒe dɔlélenutsiŋutete me. Wole abe ame kukua ƒe dedienɔnɔdzikpɔlawo ene. Ne mast cell siawo ƒo ƒu ɖe ŋutigbalẽa ƒe akpa ɖeka wògbɔ eme le susu aɖe ta la, míeyɔnae be Urticaria Pigmentosa. Ke hã, menye ŋutigbalẽa me koe mast cell siawo ate ŋu aƒo ƒu ɖo o, ke ɣeaɖewoɣi le ŋutinu bubuwo abe ƒuwo kple dɔgbowo ene me. Emegbe etrɔna zua nɔnɔme si woyɔna be ``systemic mastocytosis``. Gake megatsi dzi o, zi geɖe la, ŋutigbalẽ koe Urticaria Pigmentosa le ɖeviwo ŋu.
Le dɔléle sia me la, ne teƒe blɔ aɖe dze le ŋutigbalẽa ŋu la, etsia dzo, evuvuna, eƒonɛ, eye wòkɔna ɖe dzi abe ɖe ʋu ƒoe ene. Le atikewɔwɔ me la, woyɔa dzesi sia be ``Darier ƒe dzesi.''
Nukatae nane si le abe esia ene dzɔna?
Susu vevitɔ si tae nye ``mast cells`` si ŋu míeƒo nu tsoe va yi. Esiawo nye ʋumenugbagbevi ɣi ƒomevi aɖe si wowɔna le míaƒe ƒumeŋuɖui me. Lãmenugbagbevi siawo le míaƒe ŋutilã katã me, vevietɔ le afisiwo míedo go gotagomenuwo, abe ŋutigbalẽ, lãkusi, kple dɔgbowo ene le. Ne nane abe dɔlékui ene ge ɖe ŋutilã me la, mast cell siawo ɖea atike aɖe si woyɔna be ``histamine`` ɖe go be wòakpe ɖe ame ŋu wòakpɔ ŋutilãa ta.
Domenyiŋusẽfianu ƒe tɔtrɔ si nana mast cell siawo ƒoa ƒu ɖe ŋutigbalẽa me wògbɔa eme gbɔe Urticaria Pigmentosa tsona. Zi geɖe la, domenyiŋusẽfianu ƒe tɔtrɔ sia dzɔna ne ɖevi gakpɔtɔ le vidzidɔ me. Gake menye nane si ƒe dome wonyi tso dzilawo gbɔ na viwo o . Womeke ɖe nusi tututu gbɔ tɔtrɔ sia tso ŋu haɖe o.
Ne dɔléle sia dze ame tsitsiwo dzi la, ate ŋu asẽ vie wu. Woyɔa esia be `indolent systemic mastocytosis`. Le go sia me la, mast cells ƒoa ƒu ɖe teƒewo abe ƒumeŋuɖui ene tsɔ kpe ɖe ŋutigbalẽa ŋu. Ƒã ŋutɔ la, nɔnɔme sia ateŋu azu kansa ƒe nɔnɔme si woyɔna be `mast cell leukemia`. Gake le afisia hã la, nusiawo nye nusiwo mebɔ kura o . Urticaria Pigmentosa si dzɔna ɖe ɖeviwo dzi ƒe 99% mesẽ nenema gbegbe o.
Nukae nye dɔléle sia ƒe dzesiwo?
Dzesi vevitɔ si dze ƒã wue nye `Darier ƒe dzesi` si ŋu míeƒo nu tsoe. Eyae nye be, teƒe siwo le dzo dam la biãna eye woƒe lãme ʋãna ne wotutu wo. Tsɔ kpe ɖe eŋu la, ame aɖewo hã ate ŋu akpɔ dzesi siwo gbɔna.
| Dzesi si dzena | Numeɖeɖe bɔbɔe aɖe |
|---|---|
| Dzi ƒe tsotso | Dzi ƒe tsotso dzina ɖe edzi abe ɖe nèle vɔvɔ̃m ene. |
| Aɖuɖɔtoe (dɔgbo ƒe vevesese) . | Ate ŋu atso mast cell ƒe dɔwɔwɔ le nuɖuɖumeŋusẽ me gbɔ. |
| Flushing | Mo kple ametia ƒe akpa si le etame ƒe biã kpata. |
| Yagbɔgbɔ sesẽ (Wheezing) . | ‘Cheese-cheese’ ƒe ɖiɖi ne wole gbɔgbɔm, si ɖi asrãlélawo tɔ. |
| Alɔ̃madɔmadɔ | Ame ƒe susu ƒe dɔwɔwɔ le ʋu ƒe sisi kpata ta. |
| Taɖuame | Taɖuame. |
Urticaria Pigmentosa dɔnɔwo ƒe 75% kple edzivɔ nye ɖevi siwo mexɔ ƒe 10 haɖe o. Le ɖevi akpa gãtɔ gome la, ŋutigbalẽ koe nɔnɔme sia nɔa anyi eye wònyona ɖe edzi ne ame tsi.
Aleke ɖɔkta awɔ anya esia?
Zi geɖe la, wò ɖɔkta ate ŋu anya nɔnɔme sia bɔbɔe ne elé ŋku ɖe teƒe siwo le wò ŋutigbalẽ ŋu eye wòlé ŋku ɖe Darier ƒe dzesi ŋu. Dodokpɔ bubu aɖeke mehiã o.
Gake ne ɖikeke aɖe li be menye ŋutigbalẽ koe dɔléle sia le o, ke egblẽ nu le ŋutilã ƒe akpa bubuwo hã ŋu la, ɖɔkta ate ŋu aɖo aɖaŋu be woawɔ dodokpɔ siwo gbɔna.
- Ʋudodokpɔ (`Ʋu ƒe xexlẽme`): Srɔ̃ nu tso lãmenugbagbevi ƒomevi vovovo siwo le ʋua me kple woƒe agbɔsɔsɔ ŋu.
- Serum tryptase dodokpɔ: Ekpɔnɛ ɖa be enzyme aɖe le ʋua me si mast cells ɖena ɖe go hã.
- Bone density scan: Kpɔ alesi wò ƒuwo sesẽe ɖa.
- Ƒumeŋuɖui dodokpɔ: Ekpɔnɛ ɖa be ƒumeŋuɖui le lãmenugbagbevi siwo le lãmesẽ me wɔm hã.
Atikewɔwɔmɔnu kple alesi woaɖu dɔlélea dzii
Nya nyuiae nye be le ɖevi akpa gãtɔ gome la, Urticaria Pigmentosa akpɔ egbɔ le eɖokui si ne wole tsitsim . Atike aɖeke meli si koŋ woatsɔ axe mɔ na teƒe yeyewo be woagadze o. Teƒe siwo li fifia ate ŋu axɔ ƒe geɖe hafi woavuvu.
Zi alesi dɔlélea le ŋutigbalẽ ŋu ko la, zi geɖe la, mehiã be woawɔ atike gã aɖeke nɛ o. Wò ɖɔkta ate ŋu akafu nu siwo gbɔna be wòakpe ɖe ŋuwò nàkpɔ wò dzesiwo gbɔ:
- Atike siwo wozãna tsɔ wua ʋumenugbagbeviɣidɔ: Kpɔa ʋuʋudedi kple ʋuʋudedi dzi.
- Corticosteroid-tikewo: Tsɔe de teƒe siwo ʋuʋudedi le.
- Cromolyn sodium: Atike si wonana tsɔ daa dzesiwo abe ʋuʋudedi kple aɖuɖɔtoe ene.
- EpiPen: Mɔ̃ si wonana amesiwo ƒe nulɔdɔ sesẽ (anaphylactic reaction) be woazã le nɔnɔme kpata aɖe me. Menye amesiamee hiã esia o.
Nusiwo wòle be woaƒo asa na koŋ
Nu vevitɔ kekeake le dɔléle sia mee nye be nànɔ adzɔge tso nusiwo hea dɔlélea vɛ siwo nana dzesiawo nu sẽna ɖe edzi, si fia be nusiwo nana teƒeawo vuvu eye wobiãna.
| Atike siwo wòle be woaƒo asa na | Nu bubu siwo wòle be woaƒo asa na |
|---|---|
| Aspirin si wotsɔna ƒoa ƒui | Kamedede (vevietɔ si tea ɖeɖi ame ŋu) . |
| Ahasesẽ | Afɔkpawo tutu ŋutigbalẽa sesĩe |
| Vevesesenutsitikewo abe morphine kple codeine (`Opiates`) . | Tsi dzodzoe tsilele |
| Thiamine (Vitamin B1) . | Nunono dzodzoewo |
| Quinine (`Quinine` - asrãtike) . | Ɣe ƒe keklẽ si gbɔ eme |
| Dextromethorphan (si nye kɔdzitike) . | Vuvɔ si nu sẽ ŋutɔ ƒe amedzidzedze |
| Atike aɖewo siwo naa alɔ̃dɔdɔ ame kple X-ray amadedewo | Nuɖuɖu siwo me wodea nu ʋeʋĩiwoe, siwo me dzo le |
Vevietɔ: Ne ehiã be wò alo viwòa nano atike na dɔléle bubu la, kpɔ egbɔ be yena wò ɖɔkta nanya nu tso Urticaria Pigmentosa ŋu.
Ðe kuxiwo ate ŋu ado mo ɖaa?
Ƒã ŋutɔ la, nɔnɔme sia ateŋu ayi ŋgɔ va ɖo `systemic mastocytosis`. Ame siawo tɔgbe le afɔku gã aɖe me be woaxɔ nulɔdɔ sesẽ aɖe si woyɔna be `anaphylactic shock`, si ate ŋu ade woƒe agbe afɔku me. Ne èkpɔ dzesiwo abe gbɔgbɔ sesẽ kple susu ƒe dɔmawɔmawɔ nyuie ene la, ele be nàyi kɔdzi ƒe dɔwɔƒe si kpɔa nudzɔdzɔ kpatawo gbɔ (ETU) enumake .
Kuxi bubu siwo dona tso systemic mastocytosis me dometɔ aɖewoe nye:
- Ƒumeŋuɖui: Ƒuwo ƒe gbɔdzɔgbɔdzɔ.
- Cytopenia: Ʋumenugbagbeviwo ƒe wɔwɔme dzi ɖena kpɔtɔna le ŋutilãa me.
- Aklã me kuxiwo.
- Kansa (si mebɔ kura o).
Le afisia hã la, esiawo nye kuxi siwo mebɔ kura o. Wobɔ ŋutɔ le ɖevi siwo ŋu Urticaria Pigmentosa le me.
Gbedasi si Wotsɔ Yi Aƒeme
- Urticaria Pigmentosa nye ŋutigbalẽ ƒe dɔléle si dzea ɖeviwo koŋ dzi. Menye dɔlékuiwo xɔxɔ alo domee wònyi tso dzilawo gbɔ o.
- Dzesi vevitɔe nye be ne wotutu teƒe si le blɔ la, ezua dzĩ, vuvu, eye wònɔa ʋuʋum (`Darier ƒe dzesi`).
- Mègavɔ̃ madzemadzee o, elabena nɔnɔme sia anyo ɖe edzi le eɖokui si na ɖevi akpa gãtɔ ne wole tsitsim.
- Dɔwɔwɔ nyuie wue nye be nànɔ adzɔge tso nuɖuɖu, atikewo, kple dɔwɔna siwo nana dzesiawo nu sẽna ɖe edzi gbɔ.
- Ne dzesi siawo dometɔ aɖe le ŋuwò alo viwòa ŋu la, kpɔ egbɔ be yeyi ɖɔkta gbɔ be woakpɔ dɔlélea nyuie ahaɖo aɖaŋu si hiã.
💬 Comments (0)
Womeɖo nya aɖeke ɖe amewo haɖe o. Tsɔ wò nyaŋuɖoɖo kpe ɖe afisia zi gbãtɔ.
Tsɔ wò nyaŋuɖoɖo kpee