Ðe nèsena le ɖokuiwò me be ɖeɖi te ye ŋu eye yeƒe lãme gbɔdzɔ ɣesiaɣia? Ðe asrã, nu me ƒoƒo, eye nèsena le ɖokuiwò me be yele dɔ lém le nu suetɔ kekeake gɔ̃ hã ta? Atikewɔwɔ ƒe nɔnɔme aɖe ate ŋu anɔ megbe na nusiawo si ŋu míeƒoa nu tsoe fũ o, gake ate ŋu anye nu sesẽ ŋutɔ. Egbea míele nu ƒom tso nɔnɔme mawo dometɔ ɖeka ŋu, si nye Agranulocytosis. Mègatsi dzi o, mina míaɖe nusianu me le nya bɔbɔewo me.
Nuka tututue nye Agranulocytosis?
Kpuie ko la, esia nye ʋumenugbagbevi ɣi ƒomevi aɖe si le míaƒe ʋu me ƒe ɖiɖi si me afɔku le. Tsɔe be míaƒe ŋutilã le abe dukɔ ene. Ekema dɔlékui siwo hea dɔléle vɛ le míaƒe ŋutilã me lae nye futɔ siwo dzea dukɔa dzi. Asrafoha si wɔa avu kple futɔ siawoe nye ʋumenugbagbevi ɣi siwo le míaƒe ʋu me.
Woyɔa ŋusẽ tɔxɛ aɖe si le ʋumenugbagbevi ɣiwo ƒe aʋakɔ sia me be granulocytes . Asrafo ƒomevi vevi etɔ̃e le asrafoha sia me:
- Neutrophils ƒe dɔwɔwɔ
- Basophils ƒe lãwo
- Eosinophils ƒe lãwo
Nu suesuesue siwo le lãmenugbagbevi siawo me, siwo me enzyme siwo tsrɔ̃a dɔlékuiwo abe dɔlékui siwo gena ɖe ŋutilãa me ene le. Wowɔa lãmenugbagbevi vevi siawo le míaƒe ƒumeŋuɖui me.
Eyata agranulocytosis nye ne lãmenugbagbevi siawo siwo wɔa avu siwo woyɔna be granulocytes, vevietɔ neutrophil lãmenugbagbevi siwo bɔ wu, dzi ɖe kpɔtɔ ŋutɔ le ʋua me. Ne edzɔ alea la, míaƒe ŋutilã ƒe ametakpɔnu gblẽna keŋkeŋ kloe. Míedzea dɔléle gɔme bɔbɔe tso dɔlékui suetɔ kekeake gɔ̃ hã me.
Zi geɖe la, ele be ʋumenugbagbevi ɣi siwo wu 1,800 nanɔ ame si le lãmesẽ me le ʋu suesue lita ɖeka me. Ne xexlẽme sia ɖiɖi wu 500 la, woyɔnɛ be Agranulocytosis. Esia nye nɔnɔme si me afɔku le ŋutɔ.
Nukawoe hea agranulocytosis vɛ?
Nu vevi eve li siwo gbɔ nɔnɔme sia tsona: esiwo wodzina kple esiwo woxɔ.
1. Agranulocytosis si Wodzina:
Domenyiŋusẽfianu ƒe gbɔdzɔgbɔdzɔ aɖe gbɔe esia tsona. Wodzia ɖevi aɖewo kple ʋumenugbagbevi ɣiwo wɔwɔ le woƒe ƒumeŋuɖui me. Le kpɔɖeŋu me, dɔléle aɖe li si mebɔ o si woyɔna be Kostmann syndrome. Zi geɖe la, asrã, dɔlékuiwo, kple ƒumekuxiwo nɔa ɖevi mawo ŋu.
2. Agranulocytosis si dzɔna emegbe:
Esiae nye nɔnɔme si bɔ wu. Ate ŋu adzɔ le eƒe tsitsime le susu vovovowo ta.
| Susu | Nuɖᴐɖᴐ |
|---|---|
| Atikewo | Esiae nye nusi koŋ gbɔ wòtso eye wòbɔ wu. Atike aɖewo ate ŋu axe mɔ na ƒumeŋuɖui be wòagawɔ ʋumenugbagbevi ɣiwo o alo agblẽ lãmenugbagbevi siwo dona la dome. |
| Dɔlékuiwo | Dɔlékui aɖewo (e.g. HIV, aklãdɔ) kple dɔlékuiwo ƒe dɔléle (e.g. typhoid, yɔmekpe) ateŋu ana ƒumeŋuɖui nawɔ dɔ nyuie. |
| Vitamin ƒe anyimanɔmanɔ | Nunyiamewo abe vitamin B12 alo folate ƒe anyimanɔmanɔ le ŋutilã me. |
| Atikewɔwɔ ƒe nɔnɔme bubuwo | Ƒumeŋuɖui ƒe dɔlélewo, ƒumeŋuɖui dodo na ame, dɔléle siwo dɔlélenutsiŋutete hena vɛ abe Systemic Lupus Erythematosus (SLE) kple Rheumatoid Arthritis. |
| Susu bubuwo tae | Ahanono fũ kple nuɖuɖukuxiwo abe nuɖuɖumadzroame ene. |
Aleke atikewo hea nɔnɔme sia vɛ?
Atikewoe nye nusi gbɔ esia tsona wu. Ne èno nuwo abe atike aɖewo siwo tsia kansa nu ene la, amesiame ƒe ʋumenugbagbevi ɣiwo dzi ɖena kpɔtɔna. Gake atike aɖewo li siwo togbɔ be womehea kuxiwo vɛ na ame akpa gãtɔ o hã la, woate ŋu ahe agranulocytosis vɛ na ame ʋɛ aɖewo.
- Atike siwo wɔa dɔ to dɔlélenutsiŋutete dzi: Atike aɖewo nana míaƒe ŋutilã wɔa dɔlékuiwutike siwo dzea mía ŋutɔwo ƒe ʋumenugbagbevi ɣiwo dzi.
- Atike siwo tsia ƒumeŋuɖui nu: Atike aɖewo (e.g. valproic acid, carbamazepine, dɔlékuiwutike aɖewo abe amoxicillin) xea mɔ na ʋumenugbagbevi ɣiwo ƒe wɔwɔ le ƒumeŋuɖui me.
- Atike siwo wua kansa kple tagbɔdɔléle ƒe atike aɖewo: Esiawo hã nye nu vevi siwo nana ʋumenugbagbevi ɣiwo ƒe xexlẽme dzi ɖena kpɔtɔna.
Nu vevitɔe nye be mègadzudzɔ atike aɖeke zazã alo adze egɔme wò ɖɔkta ƒe aɖaŋuɖoɖo manɔmee o . Ne èsusu be atike aɖee le esia hem vɛ la, na wò ɖɔkta nanya enumake.
Nukae nye nɔnɔme sia ƒe dzesiwo?
Zi geɖe la, dzesi aɖeke menɔa nɔnɔme sia ŋu koŋ o. Woke ɖe eŋu le vo me ne wodo ʋu kpɔ le susu bubu aɖe ta. Gake dzesiawo dzena to dɔlékui siwo dɔlélenutsiŋutete ƒe anyimanɔmanɔ hena vɛ me.
- Asrã sesẽ si nu sẽ kpata
- Vuvɔ kple ʋuʋudedi
- Nu me ƒe abi
- Taɖuame
- Fifia ƒe ʋuʋu
- Lãmetsiŋusẽ ƒe ʋuka siwo vuvu
- Aklã alo dɔgbo ƒe vuvu
- Ðeɖiteameŋu kple ɖeɖiteameŋu ɣesiaɣi
Nusi me afɔku le wu le nɔnɔme sia mee nye be dɔlékui sue aɖe gɔ̃ hã ate ŋu ava zu dɔléle sesẽ aɖe si ate ŋu ade ame ƒe agbe afɔku me si woyɔna be sepsis . Sepsis nye nɔnɔme si me dɔlékui aɖe kaka ɖe ŋutilã bliboa me, ʋu ƒe sisi dzi ɖena kpɔtɔna afɔkutɔe, eye ŋutilãa ƒe ŋutinu ememetɔwo gɔ̃ hã te ŋu doa kpo dɔwɔwɔ. Esia nye nɔnɔme si hiã atikewɔwɔ kpata.
Ame siwo xɔ wu ƒe 65, amesiwo ŋu atikewɔwɔ me dɔléle bubuwo abe ayikudɔ alo dzidɔ ene le, ate ŋu adze kuxiwo me wu ne agranulocytosis dɔlékui aɖe dze wo dzi.
Aleke wowɔa atike nɛ?
Afɔɖeɖe gbãtɔ kple vevitɔ kekeake si woawɔ le esia dada mee nye be woadi nusi gbɔ wòtso .
- Nusi gbɔ wòtso ƒe atikewɔwɔ: Ne atike aɖe gbɔe nɔnɔme sia tso la, zi geɖe la, nɔnɔmea nyona ɖe edzi le kwasiɖa 2-3 me le atikeawo zazã dzudzɔ megbe abe alesi wò ɖɔkta gblɔe ene. Ne dɔlékui aɖe gbɔe wòtso la, ele be woadae.
- Ʋumenugbagbevi ɣiwo wɔwɔ ƒe ʋuʋu: Wodoa atike tɔxɛwo abe Filgrastim ene be woadzi ʋumenugbagbevi ɣiwo ƒe xexlẽme ɖe edzi. Esiawo doa ŋusẽ ƒumeŋuɖui eye wodzia neutrophil ƒe wɔwɔ ɖe edzi.
- Dɔlékuiwo dada: Ne dɔlékui aɖe le ŋuwò la, wò ɖɔkta aŋlɔ dɔlékuiwutikewo na wò. Le dɔlékui alo fungi ƒe dɔlékuiwo gome la, woana atike tɔxɛwo wò. Ne dɔlékuia nu sẽ la, ahiã be woaxɔ wò ɖe kɔdzi eye woawɔ atike na wò to ʋuka me (IV).
- Ƒumeŋuɖui dodo: Ne atike bubu aɖeke mewɔ dɔ nyuie o la, woate ŋu abu ƒumeŋuɖui dodo na ame si sɔ kplii be enye mɔnu mamlɛtɔ.
Aleke wòle be amesi ŋu agranulocytosis le nakpɔ egbɔe?
Ne dɔléle sia le ŋuwò la, wò dɔlélenutsiŋutete gbɔdzɔ ŋutɔ, eyata ele be nàɖɔ ŋu ɖo geɖe wu be nàkpɔ ɖokuiwò ta tso dɔlékuiwo me.
Ðo ŋku edzi be ne wò neutrophil ƒe xexlẽme ɖiɖi wu 100 hena kwasiɖa 3-4 la, mɔnukpɔkpɔ 100% li be nàxɔ dɔlékui. Eyata kpɔ egbɔ be yewɔ ɖe afɔɖeɖe siawo dzi.
| Afɔɖeɖe siwo wòle be nàwɔ atsɔ akpɔ ɖokuiwò ta tso dɔlékuiwo me | |
|---|---|
| Nuɖuɖu | Nuɖuɖu siwo woɖa nyuie koe ɖu. Ƒo asa na sabala ƒuƒu, lãmi, lã si womeɖa nyuie o, tɔmelã, azi, kple bubuawo ɖuɖu Klɔ atikutsetse kple amagbewo nyuie eye nàɖe wo ɖa hafi aɖu wo. |
| Ame ŋutɔ ƒe dzadzɛnyenye | Klɔ asi nyuie kple adzalẽ kple tsi edziedzi. Zã elektrik-lũlũmɔ̃ ɖe lãgbalẽŋudɔwɔnu teƒe. |
| Xexeãme | Ƒo asa na teƒe siwo amewo sɔ gbɔ ɖo (bɔs, keteke, sinimaɖeƒewo) yiyi. Ƒo asa na dɔwɔwɔ kple anyigba, asikaka lãwo ŋu. Ƒo asa na tsiƒuƒu le tsitawo kple tɔsisiwo me. |
| Ƒomedodo kple ame bubuwo | Ƒo asa na kadodo kplikplikpli kple amesiwo le dɔ lém (abe amesiwo ŋu asrã alo dzamezã le ene). |
Togbɔ be agranulocytosis nye dɔléle sesẽ aɖe hã la, zi geɖe la, woate ŋu adae ne wokpɔ nusi gbɔ wòtso eye wodae nyuie. Nu vevitɔe nye be nàyi ɖɔkta gbɔ ne ènya de dzesi dɔlékui ƒe dzesi suetɔ kekeake (asrã, ŋutilã ƒe vevesese). Afɔɖeɖe kaba ate ŋu akpe ɖe ŋuwò nàxe mɔ ɖe kuxi sesẽwo nu.
Gbedasi si Wotsɔ Yi Aƒeme
- Agranulocytosis nye ʋumenugbagbevi ɣi ƒomevi aɖe (vevietɔ neutrophils) si wɔa avu kple dɔlékui siwo le míaƒe ʋu me ƒe ɖiɖi si me afɔku le.
- Esia ate ŋu ana ŋutilãa ƒe dɔlélenutsiŋutete nagbɔdzɔ eye wòana dɔlékui suesuesuewo gɔ̃ hã nasẽ ŋutɔ.
- Atikewo nono, dɔlékui vovovowo, kple atikewɔwɔ ƒe nɔnɔme aɖewo koŋ gbɔe esia tsona.
- Ne dzesiwo abe asrã kpata, vuvɔ, alo nu me ƒoƒo ene dze le ŋuwò la, yi ɖɔkta gbɔ kaba.
- Ne wokpɔ dɔléle sia le ŋuwò la, ele vevie be nàɖɔ ŋu ɖo geɖe wu be nàƒo asa na dɔlékuiwo xɔxɔ.
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