Ðe nèle atikewo nom na dɔléle sesẽ aɖea? Ðe nète towo ƒe ɖiɖi sese zi ɖeka esime nèle atike mawo zãm, alo ɖe nèva nɔ ta ʋuʋum eye mèda sɔ o esime nèle zɔzɔm? Zi geɖe la, míesusuna be dɔlélea gbɔe nusiawo tso. Gake ɣeaɖewoɣi la, atike si nom nèle ate ŋu anye nusi gbɔ wòtso. Emae nye nusi míeyɔna be Ototoxicity le atikewɔwɔ me. Mègatsi dzi o, mina míaƒo nu tso esia ŋu bɔbɔe.
Kpuie ko la, nukae nye Ototoxicity?
Ne èse nya totoxicity la, adze abe nya gã aɖee wònye ene. Gake gɔmesese si le eŋu la le bɔbɔe ŋutɔ.
Oto gɔmee nye to, eye aɖi fia aɖi. Ne míagblɔe bubui la, míeyɔnɛ be aɖi si le to me
ne atike aɖewo gblẽ nu le wò to ŋu . Ele abe "aɖi tsɔtsɔ de to me ene." Sidzenuwo ƒe lãmenugbagbevi siwo le tsɛ ŋutɔ le míaƒe to ememetɔ si kpena ɖe mía ŋu míesea nu hekpɔa míaƒe dadasɔ dzi. Atike aɖewo, vevietɔ ne wozã wo le agbɔsɔsɔ gã me, ate ŋu agblẽ nu le seselelãme ƒe lãmenugbagbevi siawo ŋu. Esiae nye esime nèdzea wò to me tsotso gɔme, sea gbeɖiɖi vovovowo le wò to me (tomeʋuʋu), eye nèsena le ɖokuiwò me be yeƒe to megale dadasɔ me o.
Nu nyuitɔ kekeakee nye be ne wokpɔ nɔnɔme sia kaba , zi geɖe la, woate ŋu atrɔe ne wonya dzudzɔ atike si henɛ vɛ alo trɔe ko. Gake ne etsi megbe akpa la, ate ŋu agblẽ nu le toa ŋu tegbee.
Atike kple atike kawoe ate ŋu ana tome nawɔ aɖi?
Fifia la, wode dzesi atike siwo wu 200 siwo tsia tome. Wozãa nusiawo ƒe akpa gãtɔ tsɔ daa dɔléle sesẽwo abe kansa, dɔlékui sesẽwo, kple dzidɔ ene. Togbɔ be atike siawo le vevie be woaɖe amewo ƒe agbe hã la, ele vevie be woanya woƒe nugbegblẽ le ame ŋu. Tabla si le ete la fia atike kple atike vevi siwo hea afɔku sia vɛ.
| Atike/Atike Ƒomevi | Kpɔɖeŋuwo kple nuŋlɔɖiwo |
|---|
| Aspirin si wotsɔna ƒoa ƒui | Ne wozã atike geɖe ɣeyiɣi didi la, ate ŋu ana ame ƒe to nasesẽ eye wòana towo naɖi (tome ƒe ɖiɖi). |
| Atike siwo me quinine le | Asrãtike siwo sɔ gbɔ abe Chloroquine kple Quinidine ene ate ŋu agblẽ nu le tosese kple dadasɔ ŋu hena ɣeyiɣi aɖe. |
| Loop Diuretics ƒe atikewo | Zi geɖe la, atikewo abe Furosemide kple Torsemide, siwo wozãna tsɔ ɖea tsi ɖa le ŋutilã me la kpɔa ŋusẽ ɖe ame dzi hena ɣeyiɣi kpui aɖe. |
| Aminoglycoside Dɔlékuiwutikewo | Esiawo nye dɔlékuiwutike sesẽwo abe Gentamicin, Amikacin, Kanamycin, siwo wonana na dɔlékuiwo ƒe dɔléle sesẽwo. Woawoe nye nu vevi aɖe si hea to me aɖi vɛ. |
| Atike Siwo Wozãna Ðe Kansa Ŋu | Atike siwo wozãna tsɔ daa dɔe abe Cisplatin kple Carboplatin ene hã ate ŋu agblẽ nu le lãmenugbagbevi siwo sea nu gɔme le to me esime wole kansa lãmenugbagbeviwo wum. |
| Nutome ƒe Atikewo | Nusiwo le abe mercury, lead, kple carbon monoxide ene zazã hã ate ŋu agblẽ nu le ame ƒe to ŋu tegbee. |
Amekae le afɔku me wu?
Menye amesiame si noa atike siae axɔ aɖi si le to me o, gake ame aɖewo ya le afɔku me wu.
- Atike siwo wu ɖeka si wua tome nono le ɣeyiɣi ɖeka me: Le kpɔɖeŋu me, afɔkua lolo wu sã ne wozã loop diuretic kple aminoglycoside dɔlékuiwutike ɖekae.
- Ame siwo ŋu ayiku me kuxiwo le: Ayikuwoe ɖea atike siawo ɖa le ŋutilãa me. Ne ayikuawo mele dɔ wɔm nyuie o la, atikeawo nɔa ŋutilãa me ɣeyiɣi didi wu, si wɔnɛ be to ƒe gbegblẽ ƒe afɔkua dzina ɖe edzi .
- Atikea ƒe agbɔsɔsɔme kple ɣeyiɣi didi si woazã : Afɔkua dzina ɖe edzi ne atikeawo ƒe agbɔsɔsɔme le dzidzim ɖe edzi eye ɣeyiɣi didi si woatsɔ ada dɔa le dzidzim ɖe edzi.
Ne ele be nàno atike si xɔa ame ɖe agbe abe esia ene godoo la,
ƒo nu kple wò ɖɔkta tso afɔku si le tome ƒe aɖi me ŋu hafi nàdze atikewɔwɔ gɔme.Nukawoe nye to me aɖi ƒe dzesiwo?
Dzesi siawo ate ŋu adze egɔme kpata, alo woate ŋu adzi ɖe edzi vivivi le ɣeyiɣi aɖe megbe.
Dzesi gbãtɔwo
- Tomeʋuʋu: Esiae nye dzesi gbãtɔ si ame akpa gãtɔ dea dzesii. Gbeɖiɖi si yia edzi le to me, abe "ringing..." alo "ringing."
- Tosese fafɛ: Sese le eɖokui me abe ɖe womele nyawo sem nyuie le dzeɖoɖo si sɔ me o ene.
Dzesi siwo dzena ne nɔnɔmea nu sẽ
- Dadasɔ : Sese le ɖokuiwò me be yemeli ke o ne èle zɔzɔm, abe ɖe mèda sɔ o ene.
- Vertigo : Seselelãme si nye be wò alo nusiwo ƒo xlã wò le tsatsam.
- Oscillopsia: Nukpɔkpɔ si me mekɔ o alo nukpɔkpɔ si le titim ne èle ta ʋuʋum.
- To me yɔyɔ: Seselelãme abe ɖe ya yɔ to me ene.
- Azɔlizɔzɔ sesẽ: Azɔlizɔzɔ le viviti me sesẽ , azɔlizɔzɔ kple wò afɔwo dome be nàda asɔ.
- Taɖuame kple ɖeɖiteameŋu si gbɔ eme.
Dzesi siawo ƒe nɔnɔme toa vovo le nenye be to ɖeka alo to evea siaa ŋue wògblẽ nu le, kple alesi wògblẽe kabakabae nu.
Aleke woawɔ ade dzesi nɔnɔme sia?
Ne dzesi siwo míeyɔ ɖe etame dometɔ aɖe le ŋuwò la, ƒo nu kple wò ɖɔkta tso atike ɖesiaɖe si nèzãna ŋu. Anɔ eme be aɖo wò ɖe tosese kple dadasɔ ŋuti nunyala bibi aɖe, alo
toŋutinunyala gbɔ . Woawɔ dodokpɔwo atsɔ aɖo kpe dɔlélea dzi.
- Audiometric dodokpɔwo: Gbeɖiɖi ƒe ƒutsotsoe siwo nàte ŋu ase kple esiwo màte ŋu ase o ƒe sesẽme dodokpɔ.
- Auditory Brainstem Response (ABR) dodokpɔ: Eléa ŋku ɖe eŋu be dzesi siwo tso to ememetɔ gbɔ yi ahɔhɔ̃a gbɔ le dɔ wɔm nyuie hã.
- Otoacoustic Emissions (OAE) dodokpɔ: Doa seselelãme ƒe lãmenugbagbevi siwo le to ememetɔ ƒe dɔwɔwɔ kpɔna. (Wozãa ABR kple OAE dodokpɔ siawo koŋ tsɔ dea dzesi tosese ƒe kuxiwo le ɖevi suewo ŋu.)
- Dadasɔ dodokpɔwo: Dodokpɔ siawo dzidzea wò ŋutilã ƒe dadasɔ to nuwo abe ŋku ƒe ʋuʋu (Electronystagmogram) kple wò ŋutete be nàtsi tre ɖe anyigba vovovowo dzi (Posturography) dzidzedze me.
Aleke wowɔa atike nɛ?
Atike nyuitɔ kekeakee nye be nàdzudzɔ atike si doa dziku na ame alo nàtrɔ ɖe atike bubu ŋu,
abe alesi wò ɖɔkta gblɔe ene . Zi geɖe la, dzesiawo agatrɔ ava.
Vevietɔ wu: Mègadzudzɔ wò atikewo nono alo atrɔ atikeawo ƒe agbɔsɔsɔme gbeɖe ne mèbia wò ɖɔkta gbã o, elabena atikeawo ate ŋu anɔ vevie na wò agbe.
Gake ne womate ŋu adzudzɔ atikeawo zazã o alo ne nu gblẽ le to ŋu tegbee la, atikewɔmɔnu aɖewo li siwo ate ŋu akpe ɖe ŋuwò nàkpɔ kuxiawo gbɔ ahanɔ agbe ɖe wo nu. 1.
Tomemɔ̃wo: Mɔ̃ siawo siwo woate ŋu ado le to me alo egodo la kpena ɖe ŋuwò nèsea gbeɖiɖi siwo ƒo xlã wò nyuie wu. 2.
Tomemɔ̃: Wowɔa dɔ na mɔ̃ siawo amesiwo ƒe to me gblẽ vevie si nu sẽ akpa be tomemɔ̃wo akpe ɖe wo ŋu. 3.
Dadasɔ ƒe Atikewɔwɔ / Vestibular Rehabilitation: Esia sɔ kple kamedede hena dadasɔ. Lãmesẽdɔwɔla fiaa kamedede vovovowo wò be wòana wò tenɔnɔ, azɔlizɔzɔ, kple nuwɔwɔ ɖe ɖoɖo nu nanyo ɖe edzi.
Gbedasi si Wotsɔ Yi Aƒeme
- Tototoxicity nye nusiwo atike aɖewo gblẽna le lãmenugbagbevi siwo le to me ŋu.
- Ne èse tome ƒe ɖiɖi (tomeʋuʋu) alo taɖuame esime nèle atike sesẽwo zãm na dɔlélewo abe kansa alo dɔlékui sesẽwo ene la, na wò ɖɔkta nanya enumake.
- Ƒo asa na wò atikewo dzudzɔ alo wo ƒe agbɔsɔsɔme tɔtrɔ atikewɔlawo ƒe aɖaŋuɖoɖo manɔmee le susu aɖeke ta.
- Ne wokpɔ nɔnɔme sia kaba la, ate ŋu axe mɔ ɖe to ƒe gbegblẽ tegbee alo dadasɔ ƒe kuxiwo nu.
- Ne èsusu be aɖi le ye ŋu le atike aɖe si le nutoa me ƒe gododo me la, di atikewɔlawo ƒe aɖaŋuɖoɖo enumake. Ne ehiã la, woate ŋu axɔ nyatakaka bubuwo tso Dukɔa ƒe Aɖi Ŋuti Nyatakaka Dɔwɔƒe si le Colombo Dukɔa ƒe Kɔdzi .
Totoxicity, tosese, atikewo ƒe nugbegblẽ le ame ŋu, tomeʋuʋu, taɖuame, tosese, nugbegblẽ le ame ŋu, cisplatin, aminoglycoside, towo ƒe ɖiɖi
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Tsɔ wò nyaŋuɖoɖo kpee