Ðe atike siwo nènona le nu gblẽm le wò to ŋua? Mina míaƒo nu tso aɖi si le tome ŋu!

Èsusui kpɔ be atike aɖewo, vevietɔ esiwo wozãna tsɔ daa dɔléle sesẽwo, ate ŋu agblẽ nu le míaƒe towo ŋu, si fia be míaƒe tosese kple dadasɔ? Esia nye nusi ate ŋu adzɔ ŋutɔŋutɔ. Le atikewɔwɔ me la, míeyɔa nɔnɔme sia be totoxicity. Mègatsi dzi o, ele vevie be nànya esia. Mina míaƒo nu tso eŋu tsitotsito.

Nukae nye tome aɖi?

Kpuie ko la, to me aɖi nye nusiwo gblẽ le míaƒe to ememetɔ ŋu abe atike aɖewo ƒe nugbegblẽ le ame ŋu ene. Ne míelé ŋku ɖe gɔmesese si le nya "ototoxicity" ŋu la, "oto" gɔmee nye "to" eye "toxicity" gɔmee nye "aɖi". Eyae nye nɔnɔme aɖe abe aɖi si le to me ene. Sidzenuwo ƒe lãmenugbagbevi siwo le bɔbɔe ŋutɔ le míaƒe to ememetɔ me. Lãmenugbagbevi siawo kpena ɖe mía ŋu míesea nu hedaa asɔ le ŋutilãa me. Le kpɔɖeŋu me, atike aɖewo, atike siwo wozãna na dɔlékui sesẽwo kple atike siwo wozãna na dɔlélewo abe kansa ene, ate ŋu agblẽ nu le seselelãme ƒe lãmenugbagbevi siawo ŋu. Ɣemaɣie nɔnɔme sia si woyɔna be ototoxicity dzɔna.

Nukawoe nye to me aɖi ƒe dzesiwo?

Dzesi siawo medzena le mɔ ɖeka nu na amesiame o. Ɣeaɖewoɣi la, dzesiwo ate ŋu adze le atikeawo zazã gɔmedzedze vɔ megbe teti. Le ame bubuwo gome la, dzesiawo ate ŋu adze vivivi vivivi. Nukutɔe la, atike aɖewo ate ŋu ana dzesi siawo nadze le ƒe atɔ̃ le atikeawo zazã gɔmedzedze megbe. Zi geɖe la, dzesi gbãtɔe nye gbeɖiɖi si le ɖiɖim le to me sese. Ate ŋu anɔ abe ame aɖe si le nu ƒom na ame bubu ene, alo ate ŋu anye gbeɖiɖi "ringing" alo "whooshing" gbeɖiɖi ko. Ðɔktawo yɔa esia be tomeʋuʋu . Tomeʋuʋu ate ŋu anye tosese ƒe dzesi gbãtɔ hã. Dzesi bubuwoe nye:

• Tosese ƒe kuxi (le to ɖeka alo evea siaa me).
• Sese le ɖokuiwò me be yemegale dadasɔ me o ne èle zɔzɔm, vevietɔ ne èle atrakpuiwo liam.
• Azɔlizɔzɔ sesẽ le zã me alo le teƒe siwo do viviti.
• Ele be nàzɔ afɔwo dome be nàda asɔ.
• Oscillopsia nye seselelãme si nye be edze abe nusiwo mele ʋuʋum o le tsatsam ene. Woyɔa esia be oscillopsia .
• Sese le ɖokuiwò me be yeƒe ta le ʋuʋum, abe wò ta le tsatsam ene, abe wò abɔwo le tsatsam ene, alo be ɖeɖi te ŋuwò.

Bu alesi wòaɖe fu na wòe ne èse le ɖokuiwò me be yeƒe ta le ƒoƒom zi ɖeka esime nèle wò gbesiagbedɔwo wɔm, alo ne èdze alɔ̃dɔdɔ gɔme esime nèle zɔzɔm? Esiawoe nye dzesi siwo ŋu wòle be míalé ŋku ɖo.

Aleke esia kpɔa ŋusẽ ɖe ɖevi suewo dzii?

Ne nɔnɔme sia dzɔna ɖe ɖevi suewo dzi, vevietɔ amesiwo tsi ate ŋu asrɔ̃ nuƒoƒo la, ate ŋu anye mɔxenu gã aɖe na woƒe nusɔsrɔ̃ kple kadodo kple ame bubuwo. Abe dzilawo ene la, ele be míalé ŋku ɖe dzesi siawo ŋu ŋutɔ:

• Esesẽna be wò susu nanɔ nu ŋu, eɖanye le suku alo esime nèle nu bubu aɖe srɔ̃m o.
• Ðeɖiteameŋu kabakaba ne ele be nàɖo to ɣeyiɣi didi aɖe.
• Nusi ame bubuwo le gbɔgblɔm gɔmesese sesẽ, heheɖemegbe le nuƒoƒo me, alo nuƒoƒo kura manɔmee. Ɣeaɖewoɣi la, esia hã ate ŋu anye susu si tae ɖevi ƒe nuƒoƒo tsi megbe ɖo.

Ne ɖevi aɖe tsɔ ɖe le nane sɔsrɔ̃ me vevie, gake kasia megatsɔ ɖeke le eme o, alo ne wogblɔna ɣesiaɣi be ɖeɖi te yewo ŋu la, ele be nàbu esia ŋu vie wu be nàsusui ko be enye nu gbegblẽ wɔwɔ.

Nukatae tome aɖi sia dzɔna?

Le ɖɔktawo ƒe nya nu la, atike ƒomevi siwo wu 200 ye li siwo ate ŋu agblẽ nu le míaƒe to ememetɔ ŋu (atike siwo me aɖi le). Atike siawo dometɔ aɖewo hiã be woaŋlɔ atike na ame tso ɖɔkta gbɔ. Gake woate ŋu aƒle ɖewo, le kpɔɖeŋu me, vevesesenutsitike aɖewo, le atikedzraƒe atike aɖeke manɔmee.

Nu vevitɔe nye be le nyateƒe me la, atike siwo wogblɔna be wogblẽa nu le to ŋu dometɔ geɖe nye atike vevi siwo xɔa ame ɖe agbe. Le kpɔɖeŋu me, atike siwo wozãna na kansa, alo atike siwo wozãna na dɔlékuiwo ƒe dɔléle sesẽwo. Le nɔnɔme mawo me la, viɖe si le atikeawo nono me, si nye be wòaɖe ame aɖe ƒe agbe , sɔ gbɔ sã wu nu suesuesue siwo ate ŋu agblẽ le to ŋu.

Azɔ hã, ne wozãe le agbɔsɔsɔ gã ŋutɔ me ko hafi `(ototoxic)` atike aɖewo gblẽa nu le ame ŋu. Zi geɖe la, míenoa atike gbogbo mawo o. Atike ƒomevi vevi geɖewo li siwo ate ŋu agblẽ nu le to ŋu:

Aminoglycoside dɔlékuiwutikewo

Esiawo nye dɔlékuiwutike ƒomevi aɖe si wonana tsɔ daa dɔlékuiwo ƒe dɔlékuiwo. Tsɔ kpe ɖe kansadɔlékuiwutikewo ŋu la, wobua atikewo ƒe hatsotso sia (aminoglycosides) be eya koŋue hea to me aɖi vɛ. Kpɔɖeŋu aɖewoe nye esi:

• `(Amikacin)`
• `(Gentamicin)`
• `(Kanamycin)`
• `( Neomycin )`
• `(Netilmicin)`
• `(Streptomycin)`
• `(Tobramycin)`
• `(Vancomycin)` (Esia hã le hatsotso sia me ɣeaɖewoɣi)

Atike siwo wozãna tsɔ daa dɔlékuiwoe

Atike siwo wozãna tsɔ daa kansa ƒomevi vovovowoe. Esiawo dometɔ aɖewo ate ŋu agblẽ nu le to ŋu:

• `(Carboplatin)`
• `( Cisplatin )`

Loop diuretics - "tsi ƒe atikekuiwo".

Esiawo nye atike siwo kpena ɖe ayiku ŋu wòɖea dze kple tsi si sɔ gbɔ ɖe ŋutilãa me to aɖuɖɔ me. Ame aɖewo hã yɔa wo be "tsitikewo." Esiawo dometɔ aɖewoe nye:

• `(Bumetanide)`
• `(Ethacrynic acid)`
• `( Furosemide )` (Esia nye atike si ame geɖe nya)
• `(Torsemide)`

Atike kple atike bubuwo

Togbɔ be ƒã hã la, tome aɖi ate ŋu atso:

• Quinine:Atike siwo wonana tsɔ daa asrãdɔ.
• Salicylates : Esiawo nye vevesesenutsitike siwo womeƒlena o . Aspirin, si mí katã míenya la nye salicylate ƒomevi aɖe. Gake ne wonoe le agbɔsɔsɔ gã me eye wòxɔ ɣeyiɣi didi aɖe hafi kuxiwo ate ŋu ado mo ɖa.
• Atike siwo le nutoa me: Ɣeaɖewoɣi la, nɔnɔme sia ate ŋu atso nusiwo le abe mercury , tin, lead, kple carbon monoxide si le nutoa me gbɔ.

Nukawoe nye afɔku siwo le eme?

Afɔku si le tome aɖi ƒe nɔnɔme sia xɔxɔ me la mesɔ na amesiame o. Le atike si zãm nèle nu la, wò ɖɔkta aɖe afɔku siawo me na wò. Nusiwo bɔ dometɔ aɖewoe nye:

• Atike si ƒomevi nèzãna: Atike aɖewo ƒe afɔku le esia me wu bubuwo.
• Atikea ƒe agbɔsɔsɔme: Agbɔsɔsɔme si woano.
• Ɣeyiɣi didi kae woano atike la.
• Nenye be woano atike geɖe siwo ate ŋu agblẽ nu le to ŋu ɖekae. Ne nenemae la, afɔkua ate ŋu adzi ɖe edzi wu.

Tsɔ kpe ɖe eŋu la, dzɔdzɔmeŋutinunyalawo kpɔe be ame aɖewo ƒe domenyiŋusẽfianu (DNA) hã ate ŋu akpɔ ŋusẽ ɖe ame dzi . Vevietɔ ame aɖewo ƒe domenyiŋusẽfianu (alo woƒe wɔwɔme) ate ŋu ana tome aɖi ƒe afɔkua nadzi ɖe edzi ne wole aminoglycoside dɔlékuiwutike aɖewo nom.

Kuxi siwo dona tso tome ƒe aɖi gbɔ

Nusiwo ``ototoxic`` atike siawo gblẽna le to ememetɔ ŋu zi geɖe la ``womate ŋu atrɔe o`` . Ema fia be kuxi siwo nɔa anyi didi le tosese kple dadasɔ ŋu ate ŋu ado mo ɖa. Vevietɔ le ɖevi suewo gome la, tosese ƒe kuxi siawo ate ŋu axe mɔ na woƒe nuƒoƒo, gbesɔsrɔ̃, kple aɖaŋu siwo hiã be woatsɔ aɖo dze kple ame bubuwo gɔ̃ hã. Bu eŋu kpɔ, ne ɖevi mete ŋu sea nyawo nyuie o la, aleke wòawɔ asrɔ̃ nya mawo zazã atsɔ aƒo nu? Gake ne womate ŋu atrɔ nusiwo gblẽ o hã la, ɖɔktawo ate ŋu alé ŋku ɖe wò nɔnɔmea ŋu, ada dzesiawo ne wodo mo ɖa, eye woana kpekpeɖeŋu si hiã.

Aleke woawɔ ade dzesi nɔnɔme sia?

Ne dzesi siawo le ŋuwò la, ahiã be nàyi to, ŋɔti, kple ŋɔti ŋuti nunyala bibi (tolaryngologist alo ENT eŋutinunyala) alo toŋutinunyala gbɔ. Woawɔ dodokpɔ vovovowo atsɔ ado wò to ememetɔ kpɔ, le wò dzesiwo nu. Nu vevitɔ kekeakee nye be wò ɖɔkta ate ŋu ado wò tosese kple wò dadasɔ kpɔ hafi ana atike si wosusu be ewɔa aɖi le tome la wò.Azɔ hã, àte ŋu ana woawɔ dodokpɔ siawo ɣeaɖewoɣi esime nèle atikeawo nom. To mɔ sia dzi la, ne tɔtrɔ aɖe va abe atike la ƒe nugbegblẽ le ame ŋu ene la, àte ŋu ade dzesii kaba.

Dodokpɔ kawoe wowɔna?

Be wò ɖɔkta nakpɔ alesi wò to ememetɔ le dɔ wɔm la, ate ŋu awɔ dodokpɔwo abe esiawo ene:

• Odiogram: Esia doa alesi nèsea gbeɖiɖi vovovowo nyuie, i.e. gbeɖiɖi fafɛwo, gbeɖiɖi sesẽwo, gbeɖiɖi kɔkɔwo kple esiwo bɔbɔ (kɔkɔme), kple alesi nèse nyawo gɔme nyuie la kpɔna.
• Auditory Brainstem Response (ABR) dodokpɔ: Esia doa alesi wò tomeŋusẽ wɔa nu ɖe ​​gbeɖiɖiwo ŋui kple alesi ŋuɖoɖo ma zɔa mɔ yia ahɔhɔ̃a gbɔe kpɔna.
• Otoacoustic Emissions (OAEs) dodokpɔ: Nu nyui ŋutɔ siwo le abe taɖa ene le to ememetɔ me (fu ƒe lãmenugbagbevi siwo le to me) la doa ʋuʋudedi blewu ŋutɔ (gbeɖiɖi ƒe ʋuʋu) le gbeɖiɖi ƒe ŋuɖoɖo me. Dodokpɔ sia dzidzea ʋuʋudedi siawo be woakpɔ alesi lãmenugbagbeviawo le dɔ wɔm nyuie.
• Vestibular test battery: Esia menye dodokpɔ ɖeka ko o, ke boŋ dodokpɔ siwo kplɔ wo nɔewo ɖo be woatsɔ akpɔe ɖa be dadasɔ ƒe kuxiwo hã le eme. Le kpɔɖeŋu me, esia ate ŋu anye dodokpɔwo abe `(Videonystagmography - VNG)` (ŋku ƒe ʋuʋu kpɔkpɔ), `(Vestibular Evoked Myogenic Potentials - VEMPs)` (lãmeka siwo kpɔa gome le dadasɔ me ƒe ŋuɖoɖowo kpɔkpɔ), `(Rotary chair test)` (dodokpɔ esime wobɔbɔ nɔ zikpui si trɔna dzi), kple `(video Head Impulse Testing - vHIT)`.

Aleke wodaa aɖi si le tome?

Nublanuitɔe la, ne wodzudzɔ atike si wua tome la , metrɔa nusiwo gblẽ xoxo la o. Gake ne èdzudzɔ atikeawo zazã alo eƒe agbɔsɔsɔme dzi ɖeɖe kpɔtɔ (ne anya wɔ) ate ŋu akpe ɖe ame ŋu be wòagagblẽ nu le eŋu o. Gake abe alesi míegblɔe xoxo ene la, zi geɖe la, atike siawo siwo wua tome la xɔa ame ɖe agbe. Eyata wo nu tsotso alo tɔtrɔ gãwo wɔwɔ le wò atikewɔwɔ ƒe ɖoɖoa me manya wɔ ɣesiaɣi o. Le nɔnɔme mawo me la, wò ɖɔkta alé ŋku ɖe alesi nèwɔa nui ɖe atikeawo ŋu ŋu eye wòakpe ɖe ŋuwò nàkpɔ wò dzesiwo gbɔ.

Dɔwɔnu kple mɔnu siwo akpe ɖe ame ŋu woakpɔ dzesiwo gbɔ

Togbɔ be womate ŋu atrɔ nusiwo gblẽ le eŋu o hã la, mɔ aɖewo li siwo dzi nàto akpe ɖe ŋuwò nànɔ agbe kple dzesiawo:

• Tomemɔ̃wo: Mɔ̃ siawo kpena ɖe ame siwo ƒe to me gblẽ, vevietɔ amesiwo ƒe to mesesẽ o, ŋu be wosea nuwo nyuie wu eye wònana kadodo nɔa bɔbɔe.
• Tomemɔ̃: Esiawo nye elektrɔnikmɔ̃ siwo wotsɔa amekoko dea to me. Zi geɖe la, wozãa wo na amesiwo ƒe to me gblẽ vevie siwo mewɔa nu nyuie ne wozãa tomemɔ̃ siwo wozãna edziedzi o.
• Vestibular ƒe ɖɔɖɔɖo:Esia nye hehe tɔxɛ aɖe. Àwɔ dɔ kple vestibular therapist alo physical therapist be nàsrɔ̃ kamedede kple aɖaŋu siwo akpe ɖe wò ŋutilã ŋu wòatrɔ ɖe dadasɔ ƒe kuxi siwo to ememetɔ ƒe kuxiwo hena vɛ ŋu ahanɔ te ɖe wo nu. Esia ate ŋu akpe ɖe ŋuwò nàɖe dzesiwo abe taɖuame kple azɔlizɔzɔ sesẽ ene dzi akpɔtɔ.

Ðe woate ŋu axe mɔ ɖe aɖi si le to me nua?

Menye ɣesiaɣie woate ŋu axe mɔ ɖe nɔnɔme sia nu keŋkeŋ o. Ɣeaɖewoɣi la, ehiã be nàna atike si wua tome be wòaɖe wò agbe. Gake ne ède dzesi dzesiawo kaba la, wò ɖɔkta ate ŋu akpe ɖe ŋuwò kaba eye ɖewohĩ wòaɖe afɔ aɖewo atsɔ aɖe nusiwo agblẽ le ŋuwò dzi akpɔtɔ. Ne èle atike si ate ŋu agblẽ nu le wò to ŋu wu zãm la, wò ɖɔkta alé ŋku ɖe ŋuwò edziedzi. Agblɔ dzesi siwo ŋu wòle be nàlé ŋku ɖo kple dzesi siwo wòle be nàkpɔ ɖɔkta ne ède dzesii hã na wò.

Ɣeyiɣi didi kae nɔnɔme sia anɔ anyi?

Nusiwo to ememetɔ gblẽna le to ƒe aɖi ta la nye nusi womate ŋu atrɔ o . Esia fia be nusiwo gblẽ la nɔa anyi ɖaa. Gake le wò nɔnɔmea nu la, wò ɖɔkta ate ŋu atrɔ wò atikewɔwɔ ƒe ɖoɖoa (ne anya wɔ) be wòaxe mɔ na nusiwo agblẽ le ŋuwò kple dzesiwo be woagagblẽ ɖe edzi o. Gake esi wònye be zi geɖe la, manya wɔ be nàdzudzɔ atikeawo nono o ta la, wò ɖɔkta awɔ atikewɔwɔ ƒe ɖoɖo aɖe si anɔ anyi ɣeyiɣi didi si akpe ɖe ŋuwò nàkpɔ wò dzesiwo gbɔ. Le dɔléle si wokpɔ le ŋuwò kple atike si woŋlɔ na wò nu la, wò ɖɔkta aƒo nu na wò tso afɔku siwo le atike si wua tome nono me ŋu.

Aleke mawɔ akpɔ ɖokuinye kple vinye dzi?

• Ðo dze kple wò ɖɔkta tso afɔku siwo le atike ɖesiaɖe si wona wò me kple eƒe nugbegblẽ le ame ŋu ŋu. Mègavɔ̃ be yeabia nya o.
• Ne ède dzesi tɔtrɔ yeye aɖewo le wò tosese, dadasɔ, alo dzesi bubu aɖe ŋu le atike si nèsusu be eɖea aɖi le tome ŋu, nenye sue aɖe gɔ̃ hã, zazã vɔ megbe la, yi wò ɖɔkta gbɔ enumake.
• Ne dzila alo dɔnɔdzikpɔlae nènye si le atike sia nam ɖevi sue aɖe la, ke lé ŋku ɖe tɔtrɔ ɖesiaɖe si ava viwòa ŋu nyuie. Ate ŋu asesẽ be woakpɔ dzesiwo adze sii le ɖevi suewo ŋu. Tsɔ kpe ɖe tosese alo dadasɔ ƒe kuxiwo ƒe dzesiwo didi ŋu la, nya dzesi ɖesiaɖe si fia be viwòa le kuxi me tom be yeƒe susu nanɔ nu ŋu alo ɖeɖi tea eŋu ɣesiaɣi. Ate ŋu adzɔ be dziɖeleameƒo si me tom viwòa le ate ŋu atso tosese ƒe kuxi aɖe gbɔ. Ne nane si ŋu nètsi dzi ɖo la, yi wò ɖɔkta gbɔ hena aɖaŋuɖoɖo.

Aleke gbegbee tome aɖi dzea egɔme kabae?

Eto vovo tso ame ɖeka gbɔ yi bubu gbɔ. Ame aɖewo ate ŋu akpɔ nugbegblẽ le ame ŋu enumake ne wodze atikeawo nono gɔme. Le ame bubuwo gome la, ɖewohĩ dzesi siawo madze o vaseɖe ƒe atɔ̃ le atikewɔwɔ gɔmedzedze megbe hafi. Atikewɔwɔ kple atike aɖewo ƒe dɔwɔwɔ tsi megbe. Esia tae wòle vevie be nàwɔ tomedodokpɔ siwo wò ɖɔkta kafu be woatsɔ alé ŋku ɖe wò tosese ŋu edziedzi.

Ðo ŋku edzi be atike geɖe siwo do ƒome kple aɖi si le tome, abe dɔlékuiwutikewo kple atike siwo wozãna tsɔ daa dɔlékuiwoe ene, le vevie na agbe. Togbɔ be woate ŋu agblẽ nu le to ememetɔ ŋu hã la, viɖe siwo dona tso wo nono me, eɖanye dɔlélea dada alo ame aɖe ƒe agbe ɖeɖe o, sɔ gbɔ sã wu afɔku siwo le eme.

Ne èle atike si wonya be egblẽa nu le wò to ŋu zãm la, ƒo nu kple wò ɖɔkta tso nuxlɔ̃amedzesi ɖesiaɖe si ate ŋu anɔ dodom le wò to ememetɔ me ŋu. Zi alesi nède dzesi tɔtrɔwo kaba la, zi nenemae wò ɖɔkta ate ŋu akpe ɖe ŋuwò kaba eye wòana beléle na wò ƒe ɖoɖo si sɔ.

Nu vevitɔ kekeake si dzi wòle be míaɖo ŋkui! (Gbedasi si Wotsɔ Yi Aƒeme)

Enyo, eyata mina míalé ŋku ɖe nusiwo ŋu míeƒo nu tsoe ƒe kpukpui aɖe ŋu be wòakpe ɖe ŋuwò nàɖo ŋku nya vevi aɖewo dzi:

• Totoxicity nye nusiwo atike aɖewo gblẽna le to ememetɔ ŋu. Esia ate ŋu akpɔ ŋusẽ ɖe nusese kple dadasɔ dzi.
• Nya nyuie le dzesiwo abe tomeʋuʋu (to me ƒe ɖiɖi), tosese ƒe dɔmawɔmawɔ nyuie, kple taɖuame ŋu.
• Togbɔ be afɔkuwo li ne wole atike siwo xɔa ame ɖe agbe zãm hã la, zi geɖe la, viɖe siwo le atikeawo ŋu sɔ gbɔ wu afɔku siwo le eme. Ke hã, ele vevie be nànya afɔku siwo le eme.
• Ne woŋlɔ atike si wua tome na wò la, ƒo nu tso eŋu na wò ɖɔkta eye nàde dodokpɔ siwo ŋu wowɔ ɖoɖo ɖo la gbɔ.
• Ne ède dzesi dzesi yeye aɖewo, ne wole sue gɔ̃ hã la, gblɔe na wò ɖɔkta enumake. Atikewɔwɔ kaba ate ŋu akpe ɖe ame ŋu be nɔnɔmea nagagblẽ ɖe edzi o.

Wò agbanɔamedzie wònye be nàlé be na wò lãmesẽ. Míele mɔ kpɔm be nyatakaka sia akpe ɖe ŋuwò nàwɔe nenema!