Shin kun taɓa jin labarin acetylcholine , ko (ACh)? Wataƙila likitanku ya gaya muku game da shi, ko kuma kun karanta game da shi a wani wuri. Ƙaramin sinadari ne mai matuƙar muhimmanci a jikinmu. Kamar ƙaramin mai aika saƙo ne wanda ke ɗauke da saƙonni a cikin jikinmu. Don haka, a yau za mu yi magana game da acetylcholine ta hanya mai sauƙi da za ku iya fahimta.
Menene ainihin Acetylcholine?
A taƙaice dai, acetylcholine wani sinadari ne mai samar da ƙwayoyin jijiyoyi. Ka yi tunani a kai, kwakwalwarka tana buƙatar aika ƙananan saƙonnin lantarki don motsa hannunka, tunani, tuna wani abu, duk waɗannan abubuwa. Acetylcholine wani sinadari ne da ke taimakawa wajen ɗaukar waɗannan saƙonni ta cikin ƙwayoyin jijiyoyi .
Wannan kuma ana kiransa da "mai motsa jiki " . Shin ka san menene wannan? Yana "tayar da" ƙwayar jijiya, wato, yana ƙarfafa ta, kuma yana sa ta "aika" saƙonni da sauri. Kamar buga ƙofar mutumin da ke barci ne yake cewa, "Ga shi, ɗauki wannan wasiƙar."
Sunan acetylcholine ya fito ne daga abubuwa biyu da suka samar da shi. Ɗaya rukuni ne na acetyl . Wannan ya fito ne daga wani sinadari mai suna acetyl coenzyme A, wanda aka yi shi da sukari glucose. Ɗayan kuma sinadari ne da ake kira choline . Ana samun choline ta halitta a cikin ƙwai, waken soya, hanta, kayan lambu, da wake. Haka kuma ana samar da choline a cikin hanta.
Acetylcholine yana da hannu a cikin muhimman ayyuka da yawa a jikinmu, musamman motsin tsoka na son rai.Wannan yana taka muhimmiyar rawa a cikin ayyukanmu na hankali, kamar motsa gaɓoɓinmu da tafiya. Yana motsa ƙwayoyin jijiyoyi a cikin tsokoki, yana sa su yi ƙunci. Ba wai kawai ba, har ma yana da matuƙar muhimmanci ga ƙwayoyin jijiyoyi a cikin kwakwalwarmu, da kuma ga ayyuka kamar ƙwaƙwalwa, tunani, da koyo.
Ta yaya acetylcholine (ACh) ke aiki?
Ana adana Acetylcholine a ƙarshen ƙwayoyin jijiyoyi, har sai an aika saƙo. Lokacin da "sigina" ta iso don aika saƙo, wannan acetylcholine da aka adana yana fitowa. Da zarar an sake shi, yana tafiya zuwa ƙaramin rata tsakanin ƙwayoyin jijiyoyi guda biyu. Wannan rata ana kiransa da ƙwanƙolin synaptic .
Bayan sun ketare ƙwanƙolin synaptic, akwai nau'ikan masu karɓa guda biyu da acetylcholine zai iya haɗawa da su. Su ne:
- Masu karɓar Nicotinic
- Masu karɓar ƙwayoyin cuta na Muscarinic
Bayan an haɗa su da waɗannan masu karɓa, saƙon sinadarai yana tafiya zuwa ga ƙwayar jijiya ta gaba. Bayan an aika saƙon, acetylcholine da ke cikin tsagin synaptic ba ya ɓacewa kawai. Wani enzyme da ake kira acetylcholinesterase yana zuwa ya raba wannan acetylcholine zuwa sassan da ke cikinsa, choline da acetate. Sannan waɗannan sassan da suka lalace ana sake sha, ana sake yin amfani da su, kuma ana amfani da su don ɗaukar wani saƙon sinadarai. Tsarin da ya fi inganci!
Me ke faruwa da acetylcholine (ACh)?
Acetylcholine yana da fa'idodi da yawa ga jikinmu. Bari mu dubi manyan.
| Nau'in mai karɓa | Babban ayyuka |
|---|---|
| Masu karɓar ƙwayoyin cuta na Muscarinic |
|
| Masu karɓar Nicotinic (Nicotinic) |
|
Duk nau'ikan masu karɓa guda biyu suna da hannu a cikin ƙwaƙwalwarmu . Wato, suna da mahimmanci ga ƙwaƙwalwar ajiya ta dogon lokaci, ƙwaƙwalwar ajiya ta ɗan gajeren lokaci, samuwar tunanin, haɗakar su, da kuma dawo da su. A cikin kwakwalwa, acetylcholine yana da hannu a cikin wasu abubuwa. Yana haɓaka kwarin gwiwa, sha'awa/hankali, koyo, da barcin REM (matakin barcin da muke mafarkin sa).
Waɗanne yanayi ne ke faruwa idan matakan acetylcholine (ACh) suka ragu?
Ƙarancin matakan acetylcholine, ko rashinsa, na iya haifar da cututtuka da dama. Mafi mahimmanci daga cikinsu sune:
- Cutar Alzheimer : Mutanen da ke fama da cutar Alzheimer ba su da isasshen acetylcholine a cikin kwakwalwarsu. Sakamakon haka, rashin tunawa babban alama ce.
- Ciwon myasthenic na Lambert-Eaton : Wannan cuta tana faruwa ne sakamakon raguwar sakin acetylcholine daga ƙwayoyin jijiyoyi.
- Myasthenia gravis : Wannan cuta ce da ke haifar da garkuwar jiki wadda ke sa tsokoki na ƙashi su yi rauni da sauri bayan an sake amfani da su.
Muhimmi:Idan kana da ɗaya daga cikin waɗannan alamun, to ka ga likita nan take. Kada ka yi wa kanka bincike.
Waɗanne magunguna ne ke kai hari ga acetylcholine (ACh)?
Magungunan hana Cholinesterase rukuni ne na magunguna waɗanda ke aiki ta hanyar dakatar da aikin enzyme wanda ke rushe acetylcholine da kuma ƙara yawan aikin masu karɓar acetylcholine. Ana amfani da su don magance cutar Alzheimer da myasthenia gravis. Donepezil (Aricept®), Rivastigmine (Exelon®), da Galantamine (Razadyne®) wasu daga cikin waɗannan magunguna ne.
Waɗanne abinci ne ke ɗauke da choline, wanda ke taimakawa wajen samar da acetylcholine (ACh)?
Ana samun Choline, wani sinadari da ke canzawa zuwa acetylcholine, a cikin abinci da yawa. Misali:
- Hanta nama
- Kwai (musamman yolks)
- Zagayen naman sa na sama
- Waken soya da aka gasa, waken koda na gwangwani
- Nonon kaza da aka gasa
- Kifin cod `(Cod)`
- Quinoa da aka dafa
- Namomin kaza na shiitake da aka dafa, broccoli da aka tafasa da kuma Brussels sprouts
- Madara (1%) `(Madara (1%)`, yogurt vanilla mara kitse `(yogurt vanilla mara kitse)`
Gwada ƙara waɗannan abincin a cikin abincinka. Daidaitaccen abinci yana da matuƙar muhimmanci ga rayuwa mai kyau.
Saƙon Ɗauka Gida
To, yanzu wataƙila kun fahimci cewa acetylcholine (ACh) wani sinadari ne mai hana ƙwaƙwalwa wanda yake da matuƙar muhimmanci ga aikin kwakwalwarmu, ƙwaƙwalwa, da ayyukan jikinmu kamar matsewar tsoka. Idan matakansa suka ragu, matsalolin ƙwaƙwalwa da cututtukan da suka shafi tsoka na iya faruwa. Abu mafi mahimmanci shine, idan kuna da wata matsala ta lafiya, ku yi magana da likita game da shi. Kada ku je neman magani bisa zato. Ku kasance cikin koshin lafiya!
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