Shin ka taɓa yin mamakin yadda kake ji idan ka ƙoshi? Idan muka ci abinci, bayan wani lokaci sai mu ji "To, ya isa." Me ke haifar da wannan jin? To me yasa wasu mutane ba sa jin ƙoshi komai yawan abincin da suka ci? Leptin babban jigo ne a bayan duk wannan. Wannan hormone ne wanda yake da matuƙar muhimmanci ga sarrafa nauyin jikinmu. Bari mu yi magana a kai a hankali kuma a yau.
Mene ne Leptin, a takaice?
A taƙaice dai, leptin wani sinadari ne da ƙwayoyin kitse na jikinka (nama mai kitse) ke samarwa. An kuma san shi da "hormone mai cike da kitse." Babban aikinsa shi ne aika sigina zuwa kwakwalwarka wanda ke cewa, "To, ka sami isasshen kuzari, ka daina cin abinci." Wannan shine yadda leptin ke taimakawa wajen kiyaye nauyin jiki mai kyau a cikin dogon lokaci.
Masana kimiyya sun gano sinadarin leptin a shekarar 1994, wanda ke nufin har yanzu ana gudanar da bincike mai yawa a kansa. A halin yanzu ana binciken alaƙar Leptin da kula da nauyi, har ma da cututtuka kamar cutar Alzheimer, lafiyar haihuwa, da rashin haihuwa.
Idan ka ji kalmar "sarrafa nauyi," za ka iya tunani, "Oh... don haka za mu iya sarrafa leptin mu kuma rage nauyi." Amma gaskiyar magana ita ce, sarrafa wannan hormone yadda muke so ba abu ne mai sauƙi ba kamar yadda muke tunani.
Ta yaya leptin yake aiki a jikinmu?
Babban aikin Leptin shine taimakawa wajen kula da nauyin jikinmu. Wato, samar da daidaito na dogon lokaci tsakanin adadin abincin da muke ci da kuma kuzarin da jikinmu ke kashewa. Leptin yana hana mu jin yunwa ba tare da wata matsala ba. Yana taimakawa wajen hana jiki nuna yunwa lokacin da ba ya buƙatar kuzari (kalori).
Leptin yana aiki ne ta hanyar shafar wani ɓangare na kwakwalwarmu da ake kira hypothalamus. Duk da haka, akwai masu karɓa a wasu sassan jiki waɗanda ke amsawa ga leptin.
Mafi mahimmanci, leptin ba ya sarrafa yunwarmu daga lokaci zuwa lokaci. Madadin haka, yana aiki don sarrafa yawan cin abinci da kashe kuzari a cikin dogon lokaci, yana kiyaye nauyin jiki daidai.
Ka yi tunanin kana ƙoƙarin rage kiba. Yayin da kitsen jikinka ke raguwa, matakan leptin ɗinka suma suna raguwa. Wannan yana aika sigina zuwa kwakwalwarka cewa kana jin yunwa. Wannan yana sa ka ji yunwa sosai kuma kana da sha'awa. Wannan na iya sa ka ci abinci da yawa ba tare da ma an sani ba. Wannan shine ɗayan dalilan da yasa yake da wuya a rage kiba.
Ta yaya ake sarrafa matakan leptin?
Ana samar da Leptin kuma ana sake shi cikin jini ta hanyar farin kitsen da ke jikinmu. Saboda haka, adadin leptin da ke cikin jininka yana da alaƙa kai tsaye da adadin kitsen da ke jikinka.
- Idan kitsen jiki ya wuce kima:Matakan Leptin suna da yawa.
- Idan kitsen jiki yayi ƙasa: matakan leptin suna ƙasa.
Bayan lokaci, idan kitsen jikinka ya ƙaru, matakan leptin suna ƙaruwa, kuma idan kitsen jikinka ya ragu, matakan leptin suna raguwa.
Me zai faru idan matakan leptin suka yi yawa? - Tsarin Leptin
Mutum mai kiba yana da kitse da yawa a jikinsa. Sakamakon haka, matakan leptin a cikin jininsu suma suna da yawa. Muna kiran wannan yanayin hyperleptinemia .
Yanzu kana iya tunanin, "Idan leptin ya yi yawa, ya kamata ka ji ƙoshi, don haka ya kamata ka sarrafa cin abincinka?" Amma akasin haka gaskiya ne. Idan matakan leptin a jiki suka yi yawa na dogon lokaci, kwakwalwa ta fara rashin amsawa ga wannan siginar leptin. Kamar wani ne ke yi mana ihu koyaushe kuma mu kan yi kasa a gwiwa bayan wani lokaci. Wannan ana kiransa juriyar leptin .
A taƙaice dai, juriyar leptin na nufin cewa duk da cewa akwai isasshen leptin a jiki, kwakwalwa ba ta karɓar siginar "cikakken" ba.
Me ke faruwa saboda wannan?
1. Rashin jin ƙoshi: Ko da yake kana da isasshen kitse a jikinka, kwakwalwarka tana tunanin har yanzu kana jin yunwa. Don haka kana ci gaba da cin abinci.
2. Jiki yana shiga cikin "yanayin yunwa": Saboda kwakwalwa ba ta karɓar siginar leptin ba, kwakwalwa tana tunanin cewa jiki ba shi da isasshen kuzari kuma muna jin yunwa. Don haka, don adana kuzari, ƙimar metabolism na basal na jiki (BMR) yana raguwa. Wannan yana nufin cewa adadin kalori da kuke ƙonawa yayin da kuke zaune kawai yana raguwa.
Ta wannan hanyar, juriyar leptin, a gefe guda, yana ƙara yunwa kuma yana ƙara yawan abincin da ake ci, a gefe guda kuma, saurin ƙona kalori da jiki ke yi yana raguwa. Idan waɗannan abubuwa biyu suka haɗu, sakamakon yana ƙara ƙaruwar nauyi.
| Babban fasali na juriyar Leptin |
|---|
| Kullum ina jin yunwa sosai (hyperphagia) duk da ƙarancin kitse ko babu kitse a jiki. |
| Wahala wajen sarrafa yawan cin abinci da kuma yawan cin abinci. |
Waɗannan alamun na iya faruwa ne sakamakon wasu dalilai, don haka idan kuna fuskantar waɗannan alamun, ya fi kyau ku yi magana da likitan ku.
Me zai faru idan matakan leptin suka ragu?
Rashin Leptin wani yanayi ne da ba kasafai ake samunsa ba . Yawanci yana faruwa ne da wata cuta ta kwayoyin halitta da ake kira rashin leptin na haihuwa . Mutumin da ke da wannan yanayin yana da yanayin da ƙwayoyin kitsensa ba za su iya samar da leptin ba.
Idan babu leptin, jiki yana tunanin cewa babu kitse a jiki. Wannan yana nuna cewa kwakwalwa tana jin yunwa kuma ba za ta iya sarrafa ta ba. Sakamakon haka, ƙananan yara masu wannan yanayin suna da sha'awar cin abinci mara iyaka. Sakamakon haka, suna yin kiba sosai (kiba ta aji na uku) a lokacin ƙuruciya kuma suna fuskantar jinkirin balaga.
| Yanayi da ka iya dangantawa da yawan leptin (hyperleptinemia) | Yanayi da ka iya dangantawa da ƙarancin matakan leptin (Hypoleptinemia) |
|---|---|
| Damuwa | Yawan insulin a jiki (hyperinsulinemia) |
| jarabar abinci | Rashin daidaiton kitse a jini (dyslipidemia), misali cholesterol, triglycerides |
| Cutar hanta mai kitse mara barasa | Ciwon hanta mai kitse |
| Matsalolin da ke haifar da lalacewar jijiyoyi (neuropathy) | Cututtukan ƙwayoyin cuta akai-akai |
Za a iya auna matakan leptin a cikin jini?
Eh, gwajin jini mai sauƙi zai iya auna matakan leptin. Duk da haka, wannan ba gwaji ne da likitoci suka saba ba. Ana yin sa ne kawai a lokuta na musamman. Misali:
- Idan yaro ƙarami yana da kiba sosai.
- Idan mutum mai kiba ya ci gaba da fama da yunwa mara misaltuwa.
Yawanci, matakan leptin masu lafiya na iya kasancewa daga:
- Mata: 0.5 - 15.2 ng/ml (nanograms da milliliter)
- Namiji: 0.5 - 12.5 ng/mL
Waɗannan dabi'u na iya bambanta kaɗan daga dakin gwaje-gwaje zuwa dakin gwaje-gwaje, don haka idan kuna da wata shakka game da dabi'un da ke cikin rahoton ku, tambayi likitan ku.
Ta yaya muke daidaita matakan leptin?
Babu wata hanyar da za a ƙara yawan leptin ta hanyar wucin gadi don rage yunwa, domin matakan leptin suna da alaƙa kai tsaye da yawan kitsen da ke jikinka.
Duk da haka, akwai abubuwa da yawa da zasu iya taimakawa wajen daidaita aikin leptin da sauran ma'aunin hormones:
1. Samun isasshen barci: Wani bincike ya gano cewa rashin isasshen barci yana ƙara sinadarin ghrelin na yunwa kuma yana rage sinadarin leptin na satiety. Saboda haka, samun isasshen barci kowace rana yana da matuƙar muhimmanci ga daidaiton hormones.
2. Cin abinci mai kyau: Wasu bincike sun nuna cewa yawan sinadarin triglycerides, wani nau'in kitse a cikin jini, na iya hana leptin isa kwakwalwa. Duk da cewa har yanzu akwai ra'ayoyi daban-daban game da wannan, ya fi kyau a ci abinci mai kyau wanda ya haɗa da kayan lambu, 'ya'yan itatuwa, zare, furotin mai kyau, da kitse mai lafiya, yayin da ake rage sukari, fulawa, da abinci da aka sarrafa .
3. Motsa jiki akai-akai: Bincike ya nuna cewa motsa jiki na iya taimakawa wajen rage juriyar leptin. Wato, motsa jiki na iya inganta yanayin leptin a cikin kwakwalwa.
Abu mafi muhimmanci shi ne, leptin ba wani abu bane da ake samu a cikin abinci. Hormone ne da jikinmu ke samarwa da kansa. Don haka babu wani abu kamar "cin leptin da yawa."
Idan kana damuwa game da nauyinka, ko kuma kana buƙatar jagora kan yadda za ka rage kiba ta hanyar da ta dace, ya fi kyau ka yi magana da likitanka . Idan ya zama dole, zai iya tura ka zuwa ga likitan endocrinologist.
Saƙon Ɗauka Gida
- Leptin wani sinadari ne mai "cikakke" wanda ƙwayoyin kitse na jikinmu ke samarwa. Yana nuna wa kwakwalwa cewa mun sami isasshen abinci.
- Yayin da kitsen jikinka ke ƙaruwa, matakan leptin suma suna ƙaruwa.
- Babbar matsalar kiba ba rashin leptin ba ce, amma wani yanayi ne da ake kira "resistance of leptin," wanda kwakwalwa ba ta mayar da martani ga leptin.
- Juriyar Leptin tana ƙara yunwa da rage ƙona kalori a jiki, wanda hakan zai iya haifar da ƙarin ƙaruwar nauyi.
- Samun isasshen barci, abinci mai kyau, da motsa jiki suna taimakawa wajen kiyaye aikin leptin da kuma daidaiton hormones gaba ɗaya.
- Idan kana da wata damuwa game da nauyinka ko tsarin cin abinci, koyaushe ka tuntuɓi likitanka don neman shawara.
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