Shin kana jin kamar ba ka jin daɗi, kana rashin lafiya koyaushe, ko kuma kana zubar da jini ko da ƙaramin rauni ne, ko kana shan maganin ciwon daji ko wata cuta? Bayan waɗannan abubuwan, akwai yiwuwar samun myelosuppression , wani yanayi da bargon ƙashi ba ya aiki yadda ya kamata . Kada ka damu, bari mu yi magana a kan wannan a taƙaice.
Menene myelosuppression? A takaice dai, shin raunin ƙashi ne?
A taƙaice dai, eh! Bargo nama ne mai laushi da laushi a cikin ƙasusuwanku. Ku yi tunaninsa kamar masana'antar yin jini ta jikinmu. Wannan masana'anta tana samar da biliyoyin ƙwayoyin jini ja, fararen ƙwayoyin jini, da kuma ƙwayoyin platelets, waɗanda suke da mahimmanci don rayuwarmu, kuma suna ƙara su cikin jininmu. Kowace nau'in ƙwayar halitta tana da aiki daban-daban ga jikinmu. Bargo na ƙashi yana ƙaruwa ko rage wannan samarwa ya danganta da buƙatun jikinmu.
Yanzu, a cikin wani yanayi da ake kira myelosuppression , aikin wannan masana'antar ƙashi ya lalace saboda wani dalili. Sannan, ba za a iya samar da ƙwayoyin jini da platelets yadda ya kamata ba. Babban dalilin hakan shine maganin chemotherapy don ciwon daji. Duk da haka, wasu nau'ikan ciwon daji na jini da wasu ƙwayoyin cuta suma suna iya haifar da gazawar ƙashi.
Mene ne alamun myelosuppression?
Alamomin na iya bambanta daga mutum zuwa mutum, ya danganta da ko ƙashin ƙashin ku yana samar da ƙwayoyin jini ja, ƙwayoyin jini fari, ko kuma ƙwayoyin platelets.
Idan ƙwayoyin jinin ja suka ragu - Anemia
Kwayoyin jinin ja suna ɗauke da iskar oxygen a cikin jikin mutum. Idan babu isasshen su , anaemia na tasowa. Alamomin na iya haɗawa da:
- Gajiya
- Takaitaccen numfashi / dyspnea
- Jin jiri
- bugun zuciya mai sauri ko mara tsari / arrhythmia
- Jin sautin ƙara a cikin kunnuwa, wani lokacin tare da sautin "busa" da bugun zuciya (Pulsatile tinnitus)
- Ciwon kai
- Faɗin launin fata
- Ciwon ƙirji
Neutropenia - raguwar ƙwayoyin jinin fari (musamman neutrophils)
Farin ƙwayoyin jini suna yaƙi da ƙwayoyin cuta da ke shiga jikinmu kuma suna kare mu daga kamuwa da cuta . Wani nau'in ƙwayoyin jinin farin ana kiransa neutrophils . Idan ɓawon ƙashi ya samar da ƙarancin neutrophils saboda myelosuppression, ana kiran wannan yanayin neutropenia . Neutropenia ba shi da wata takamaiman alama, amma saboda wannanAna iya samun kamuwa da cuta akai-akai, kuma a lokacin ne alamun cutar ke bayyana.
- Zazzabi (wani lokacin ana kiransa zazzabin neutropenia )
- Gajiya
- Ciwon makogwaro/kamuwa da cuta (Ciwon makogwaro/pharyngitis)
- Kumburin lymph da ke kumbura
- Ciwon ciki a baki ko a kusa da dubura
- Gudawa
- Konewa yayin yin fitsari, jin kamar kana buƙatar yin fitsari da sauri, yawan yin fitsari
Idan platelets suka ragu - thrombocytopenia
Platelets suna taimakawa wajen sarrafa zubar jini . Idan waɗannan matakan suka ragu, wata cuta da ake kira thrombocytopenia na faruwa. Wannan na iya haifar da:
- Zubar jini wanda baya tsayawa na dogon lokaci, ko da kuwa daga ƙaramin rauni ne, ko kuma wahalar dakatar da zubar hanci.
- Kuraje suna bayyana da sauri fiye da yadda aka saba.
- Bayyanar ƙananan tabo ja (kamar kurji) a ƙananan ƙafafu - wannan ana kiransa petechiae .
- Tabo ja, shunayya, ko launin ruwan kasa a fata - wannan ana kiransa purpura .
Idan duk nau'ikan ƙwayoyin jini sun ragu - Pancytopenia
Wani lokaci, dukkan waɗannan ƙwayoyin jini guda uku—ƙwayoyin jini ja, ƙwayoyin jini fari, da kuma platelets—na iya yin ƙasa a lokaci guda . Wannan yanayin ana kiransa pancytopenia . Kamar neutropenia, wannan ba cuta ba ce da kanta, amma tana iya zama alamar wata cuta ta rashin lafiya.
Me yasa myelosuppression ke faruwa? Menene abubuwan da ke haifar da hakan?
Kamar yadda muka ambata a baya, maganin chemotherapy shine mafi yawan sanadin . Duk da haka, akwai wasu dalilai kuma.
Chemotherapy, immunotherapy, da myelosuppression
Nau'o'in magungunan chemotherapy da dama na iya haifar da hakan. Wasu daga cikin waɗanda suka fi yawa sune:
- Fluorouracil
- Oxaliplatin
- Irinotecan
- Capcitabine
Bugu da ƙari, maganin ƙwayoyin CAR T, wani nau'in maganin rigakafi , yana iya lalata aikin ƙashi da rage samar da ƙwayoyin jini da platelets.
Ciwon Daji na Jini da kuma Ciwon Hawan Jini
Wasu cututtukan daji na jini na iya yin katsalandan ga samar da ƙwayoyin jini na yau da kullun. Misali, a cikin cututtukan daji kamar su cutar sankarar bargo, lymphoma, da myeloma , ƙwayoyin cutar daji marasa kyau suna girma sosai a cikin ƙashi kuma suna dakatar da samar da ƙwayoyin jini masu lafiya da platelets.
Ƙwayoyin cuta da kuma myelosuppression
Wasu cututtukan ƙwayoyin cuta na iya kawo cikas ga tsarin samar da jini a cikin bargon ƙashi. Ka yi tunanin cewa idan kwayar cuta ta shiga jiki, tsaron jikinmu, wato fararen ƙwayoyin jini, suna yaƙi da kwayar cutar. A lokacin wannan faɗa, bargon ƙashi na iya samar da ƙaramin adadin ƙwayoyin jinin ja da platelets. Wasu bincike sun nuna cewa wasu ƙwayoyin cuta suna kamuwa da ƙwayoyin halittar jini kai tsaye a cikin bargon ƙashi, suna rage adadin ƙwayoyin jini. Wasu ƙwayoyin cuta da aka gano suna da alaƙa da wannan yanayin myelosuppression sune:
- Kwayar cutar Epstein-Barr (EBV)
- Cutar Hepatitis C
- Parvovirus B19
- Kwayar cutar Cytomegalovirus (CMV)
- Kwayar cutar da ke haifar da cutar kyanda (Chickenpox / varicella zoster)
- Kwayar cutar kanjamau (HIV)
- Zazzabin Dengue
Shin myelosuppression zai iya haifar da matsaloli masu tsanani?
Haka ne, wani lokacin wannan na iya haifar da matsaloli masu barazana ga rayuwa . Misali, faɗuwar ƙwayoyin jinin ja (anemia mai tsanani) ko faɗuwar ƙwayoyin platelets (zubar da jini mara iko) .
Muhimmi: Idan ka fuskanci ɗaya daga cikin waɗannan alamomin, musamman idan kana shan maganin ciwon daji, yana da matuƙar muhimmanci ka nemi shawarar likita nan take.
Ta yaya likitoci suke gano wannan yanayin daidai?
Ana gano wannan ta hanyar gwaje-gwajen jini . Waɗannan gwaje-gwajen jini suna duba ko bargon ƙashin ku yana samar da ƙwayoyin jini da ƙwayoyin platelets yadda ya kamata.
Ana iya yin gwajin jini kamar haka:
- Cikakken ƙidayar jini (CBC)
- Gwajin MCV (Matsakaicin girman jiki / gwajin MCV)
- Gwajin RDW (Faɗin rarraba ƙwayoyin ja / gwajin RDW)
- Adadin reticulocytes
- Gwaji na jini na gefe
- Gwajin MPV (Matsakaicin girman platelet / gwajin MPV)
Menene hanyoyin magance myelosuppression?
Likitoci suna magance wannan ta hanyar amfani da waɗannan hanyoyin:
- Idan maganin chemotherapy ne ke haifar da myelosuppression, ya kamata a rage yawan maganin chemotherapy ko a dakatar da shi na ɗan lokaci .
- Zubar da jini don ƙara yawan ƙwayoyin jinin ja da kuma ƙwayoyin platelet.
- Ba ku magunguna da ke taimaka wa ƙashin ku ya samar da ƙarin ƙwayoyin jini da platelets.
Za a iya hana wannan yanayin faruwa?
Sau da yawa cutar myelosuppression tana faruwa ne a matsayin illa ga magungunan ciwon daji. Saboda haka, likitoci suna ci gaba da neman waɗannan illolin yayin maganin ciwon daji. Za su duba jinin ku akai-akai kuma su yi canje-canje ga tsarin maganin ku idan ya cancanta.
Me zan iya tsammani idan ina da myelosuppression?
Mutane da yawa suna kamuwa da wannan yanayin ne saboda suna shan maganin chemotherapy. Idan haka ne, likitanka zai sa ido sosai kan yadda maganin chemotherapy ke shafar ƙashin ƙashinka. Kuna iya buƙatar ɗaukar ɗan gajeren hutu daga maganin ciwon daji don ba wa ƙashin ƙashinka damar sake gina yawan ƙwayoyin jininsa.
Ta yaya zan kula da kaina?
Hawan jini na iya ƙara haɗarin kamuwa da cututtuka da zubar jini . Za ku iya yin waɗannan abubuwa don rage wannan haɗarin:
- A yi allurar rigakafi don kare kai daga ƙwayoyin cuta da aka saba gani.
- Yin kyawawan halaye na tsafta , kamar wanke hannu akai-akai da kuma nisantar mutanen da ba su da lafiya.
- Kare kanka daga yanayin da za ka iya ji rauni ko yanke jiki . Misali, ka yi taka-tsantsan lokacin amfani da makamai masu kaifi.
Wadanne tambayoyi ya kamata in yi wa likitana?
Za ka iya yi wa likita tambayoyi kamar:
- Me yasa nake da wannan yanayin myelosuppression?
- Ta yaya wannan yanayin yake shafar jikina?
- Waɗanne zaɓuɓɓukan magani nake da su?
- Shin magani zai warkar da ciwon myelosuppression gaba ɗaya?
Takaitawa: Abin da za a tuna (Saƙon Ɗauka Gida)
Bargon ƙashi muhimmin ɓangare ne na jikinka. Jajayen ƙwayoyin jini waɗanda ke ɗauke da iskar oxygen, fararen ƙwayoyin jini waɗanda ke yaƙi da kamuwa da cuta, platelets waɗanda ke taimakawa wajen gudan jini - duk ana yin su a can. Myelosuppression shine lokacin da bargon ƙashi ya daina aiki saboda wani dalili. Babban abin da ya fi faruwa shine chemotherapy don ciwon daji, amma kuma yana iya faruwa ne sakamakon wasu cututtukan jini da ƙwayoyin cuta. Kada ku damu. Likitoci za su gano musabbabin kuma su yi maganinsa daidai. Abu mafi mahimmanci shine neman kulawar likita idan kuna da wasu alamu marasa kyau kuma ku bi shawararsu a hankali. Ba kai kaɗai ba ne, kuma akwai likitoci waɗanda za su iya taimaka muku a wannan tafiya.
` Myelosuppression, Rage Madarar Kashi, Madarar Kashi, Kwayoyin Jini Ja, Kwayoyin Farin Jini, Platelets, Chemotherapy, Cancer, Anemia, Neutropenia, Thrombocytopenia, Cututtuka
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