Menene Ciwon POEMS? Shin kuna son sanin wannan ma?

Shin kun taɓa jin labarin Ciwon POEMS? Wannan cuta ce da ba kasafai ake jin ta ba. Duk da haka, yana da muhimmanci a san kaɗan game da ita domin tana iya shafar tsarin jikinmu da yawa a lokaci guda. A taƙaice dai, cuta ce mai sarkakiya da ke da alaƙa da jininmu. A yau, za mu yi magana game da menene Ciwon POEMS, menene alamunsa, ta yaya ake gano shi, da kuma ko akwai magani.

Menene ainihin cutar POEMS?

To, bari mu ga menene Ciwon POEMS. Wannan cuta ce ta jini da ba kasafai ake samu ba. Muna da wani nau'in ƙwayar jini da ake kira ƙwayoyin plasma a jikinmu. Lokacin da ciwon POEMS ya faru, waɗannan ƙwayoyin plasma suna rabuwa kuma suna ninkawa ba bisa ƙa'ida ba, ba tare da wata matsala ba. Waɗannan ƙwayoyin plasma marasa kyau suna fitar da wani furotin na musamman a cikin jininmu. Ana kiransa furotin monoclonal, ko M-protein a takaice. Yanzu za ku iya tunanin, ko? Lokacin da waɗannan ƙwayoyin plasma marasa kyau, M-protein, suka ƙaru da yawa a cikin jini, yana iya lalata jijiyoyi da gabobin ciki.

Sunan POEMS ya samo asali ne daga haruffan farko na biyar daga cikin manyan alamomin wannan cuta:

• P - Polyneuropathy: Wannan yana nufin lalacewar jijiyoyi a ko'ina cikin jiki. A cikin WAƘOƘI, wannan lalacewar na iya haifar da ciwo ko wasu abubuwan da ba su da daɗi (kamar ƙara, ƙonewa, da sauransu) a ƙafafunku, hannaye, tafin ƙafafu, da hannaye.
• O - Organomegaly: Wannan yana nufin cewa gabobin ciki suna girma ba kamar yadda ya kamata ba. Mutumin da ke da POEMS yana iya samun manyan gabobi kamar hanta, saifa, da kuma ƙwayoyin lymph.
• E - Endocrinopathy: A takaice dai, wannan matsala ce ta hormonal. A cikin WAƘOƘI, adadin hormones da glandar endocrine ɗinmu ke fitarwa na iya zama ba daidai ba. Wasu hormones na iya fitowa da yawa ko kaɗan.
• M - furotin na Monoclonal (M-protein): Wannan shine furotin na musamman da ke taruwa a cikin jini a cikin WAƘOƘI. Lokacin da ƙwayar plasma guda ɗaya ta yi kwafi da yawa (clones) na kanta, kowace ƙwayar tana ƙara wannan furotin na M a cikin jini. Daga ƙarshe, adadin furotin na M a cikin jini yana ƙaruwa sosai.
• S - Canjin fata: Mutanen da ke da WAƘOƘI na iya fuskantar canje-canje daban-daban na fata, kamar duhun fata da kauri na fata.

Ana kuma san ciwon POEMS da osteosclerotic myeloma , Crow-Fukase syndrome , PEP syndrome , da Takatsuki syndrome .

Wanene ya fi kamuwa da cutar POEMS?

Ciwon POEMS wata cuta ce da ba kasafai ake samunta ba. Tana shafar mutane ƙalilan ne kawai a duk duniya. An fi ganinta a tsakanin mutane tsakanin shekaru 50 zuwa 60. Tana iya shafar jinsi biyu, amma da alama ta fi shafar maza.

Mene ne alamun cutar POEMS?

Kamar yadda muka ambata a baya, haruffan da ke cikin sunan POEMS suna nuna wasu daga cikin manyan alamomin. Wato, Polyneuropathy, Organomegaly, Endocrinopathy, M-protein, da canje-canjen fata sune manyan alamomin. Kusan duk wanda ke da POEMS yana da polyneuropathy da M-protein. Sauran alamun na iya bambanta daga mutum zuwa mutum.

Alamomin da ke haifar da polyneuropathy

Alamomin da wannan lalacewar jijiyoyi ke haifarwa su ne suka fi yawa a cikin WAƘOƘI. Sau da yawa, ciwon yana yawan fitowa ne a ƙafafu da ƙafafu. Amma wani lokacin yana iya shafar hannaye da hannuwa. Ga yadda za ku ji idan kuna da wannan yanayin:

• Rauni
• Tingling
• Jinkiri
• Jin sautin ƙaiƙayi / ƙwanƙwasawa da allura
• Jin zafi a cikin ƙuna

Organomegaly - faɗaɗa gabobin ciki

Hanyoyin daukar hoto da likitoci ke yi na iya gano ko waɗannan gabobi sun faɗaɗa:

• Hanta (Hanta - `(Hepatomegaly)`)
• Kwakwalwa (Splenomegaly)
• Ƙwayoyin Lymph (Ƙwayoyin Lymph - `(Lymphadenopathy)`)

Endocrinopathy - matsalolin hormonal

Babbar matsalar hormones da ke tare da POEMS ita ce raguwar matakan hormones na jima'i. Waɗannan hormones na jima'i ana kiransu "Testosterone" a cikin maza da "Estrogen" a cikin mata. Bugu da ƙari, kuna iya ganin alamu kamar:

• Matsalolin da ke shafar matakan sukari a jini (misali ciwon suga)
• Matsalolin thyroid (misali Hypothyroidism)
• Cutar Addison (Rashin isasshen adrenal - `(Cutar Addison)`)

Maza na iya fuskantar raguwar haihuwa da kuma girman nono (Gynecomastia).

Ga mata , jinin haila na iya tsayawa (`(Amenorrhea)`), nono na iya girma. A lokacin daukar ciki, ana iya samar da sinadarin hormone `(Prolactin)`, wanda ke taimakawa wajen samar da madara fiye da kima. Saboda haka, madara na iya zubewa daga nonon koda kuwa ba ki da juna biyu.

Ƙara yawan furotin na M

Babban abin da ke cikin POEMS shine yawan sinadarin M a cikin jini. Wannan yawan sinadarin M a cikin jini na iya haifar da samuwar ciwace-ciwacen jini. Haka kuma, saboda yawan sinadarin M a cikin jini, sinadarin M a cikin jini yana da kyau.Kasusuwa na iya zama masu kauri da tauri (osteosclerosis) .

Canje-canjen fata

Canje-canje daban-daban na fata na iya faruwa, kamar:

• Fata mai duhu
• Fata mai kauri
• Fararen farce
• Ƙara girman gashi a fuska da ƙafafuwa
• Girman jijiyoyin jini waɗanda ke kama da ƙananan ceri a kan fatar ƙirji

Wasu alamomin

Baya ga wannan, ana iya ganin wasu alamu:

• Kumburin hannu da ƙafafu
• Rage nauyi ba tare da wani dalili ba
• Jin zafi a ƙasusuwa da gidajen abinci
• Matsalolin gani
• Wahalar numfashi
• Gajiya
• Zazzaɓi

Wasu mutanen da ke fama da cutar POEMS suma suna iya samun wata cuta da ake kira Castleman Disease (CD), wadda ke shafar ƙwayoyin lymph. Idan kana da alamun cutar Castleman Disease, likitanka zai iya zargin POEMS.

Me ke haifar da ciwon POEMS?

Idan kana da WAƘOƘI, kana fuskantar alamu da sakamako iri-iri saboda matsalar ƙwayoyin plasma na monoclonal . A taƙaice dai, ƙwayar plasma mara kyau tana yin kwafi da yawa na kanta. Da yawan waɗannan ƙwayoyin suna nan, to ƙarin lalacewar da za su iya yi wa kyallen jiki. Waɗannan ƙwayoyin suna ƙara furotin na M a cikin jini, wanda ke sa adadin furotin na M a cikin jini ya ƙaru. Waɗannan ƙwayoyin da suka wuce gona da iri da furotin na M ne ke lalata tsarin jiki daban-daban.

Duk da haka, masana kimiyya har yanzu ba su san ainihin dalilin da ya sa waɗannan ƙwayoyin plasma ke fara girma ba daidai ba tun farko.

Masu bincike sun gano cewa wani furotin mai suna Vascular Endothelial Growth Factor (VEGF) yana iya shiga ciki. Yawancin mutanen da ke fama da cutar POEMS suna da yawan VEGF a cikin jininsu. Har yanzu ana ci gaba da bincike kan dangantakar da ke tsakanin VEGF da cutar POEMS.

Ta yaya ake gane cutar POEMS? (Ganewar asali)

Da farko likitanka zai tambaye ka game da tarihin lafiyarka da kuma alamomin da ke tattare da kai a yanzu. Sannan, za su yi gwajin jiki don duba alamun cutar POEMS.

Bugu da ƙari, likita zai iya yin gwaje-gwaje da dama, kamar:

• Gwajin jini da fitsari: Waɗannan gwaje-gwajen na iya taimakawa wajen duba yawan ƙwayoyin M-protein ko VEGF a cikin jininka ko fitsarinka. Haka kuma za su iya duba ko akwai ƙwayoyin jini marasa kyau ko kuma ƙwayoyin jini marasa kyau. Waɗannan na iya zama alamun WAƘOƘI.
• Gwaje-gwajen hoto: Gwaje-gwaje kamar X-ray da CT scans na iya nuna ko ƙasusuwanku sun yi kauri ko sun yi tauri. Waɗannan canje-canje na iya faruwa lokacin da matakan M-protein suka ƙaru.
• Binciken ƙwayoyin halitta na ƙashi: Wannan zai iya gano ko kuna da ƙwayoyin plasma marasa kyau a cikin ƙashin ku, ko kuma idan adadin ƙwayoyin plasma ya yi yawa.
• Electromyogram (EMG): EMG gwaji ne da ke auna ayyukan jijiyoyi. Yana iya taimaka wa likitanka ya gano cutar polyneuropathy.

Dangane da alamun cutar, likitanka zai iya yin ƙarin gwaje-gwaje, kamar gwaje-gwajen numfashi, echocardiograms, ko gwaje-gwajen endocrine.

Idan an gano cewa kana da wata cuta da ake kira Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) , likitanka zai iya gwada ka don ganin ko kana da cutar POEMS.

Ta yaya ake kula da ko magance cutar POEMS?

Babu maganin cutar POEMS. Duk da haka, jiyya na iya taimakawa wajen sarrafa da kuma sarrafa alamun. Zaɓuɓɓukan magani sun haɗa da:

• Maganin radiation: Wannan ya ƙunshi jagorantar yawan radiation a cikin ƙwayoyin plasma marasa kyau don lalata su.
• Maganin Chemotherapy: Ana amfani da magungunan hana ciwon daji, wanda aka fi sani da "Chemotherapy," don kashe ko rage girman ƙwayoyin plasma marasa kyau. Maganin Chemotherapy don POEMS yayi kama da maganin myeloma da yawa. Waɗannan jiyya suna da tasiri sosai kuma galibi ba sa haifar da mummunan sakamako.
• Dashen ƙwayoyin halitta masu aiki da kansu: Wannan tsari yana maye gurbin ƙwayoyin halitta marasa aiki da ƙwayoyin halitta masu lafiya. Kwayoyin halitta sune ƙwayoyin da ke girma zuwa manyan ƙwayoyin halitta kamar ƙwayoyin halitta na plasma. A cikin wannan dashen, likitanka da farko yana cire wasu ƙwayoyin halitta masu lafiya daga jikinka. Sannan, suna amfani da maganin chemotherapy ko radiation don lalata ƙwayoyin halitta marasa aiki. Bayan maganin, ana mayar da ƙwayoyin halitta da aka cire cikin jikinka. Sannan suna girma zuwa ƙwayoyin halitta masu lafiya.
• Maganin motsa jiki: Idan kana da wahalar tafiya saboda cutar polyneuropathy, wannan maganin zai iya taimakawa.

Bugu da ƙari, likita zai iya rubuta magunguna kamar steroids don rage alamun cutar da kuma magungunan diuretics (kwayoyi na ruwa) don rage kumburi.

Mene ne matsalolin da ke tattare da cutar POEMS?

Tare da ciwon POEMS, lalacewar jijiyoyi da rauni na iya ƙaruwa akan lokaci. Hakanan yana iya sa ya zama da wahala a zagaya. Idan ruwa ya yi yawa kusa da huhu ko cikin ramin ƙirji, yana iya haifar da ciwon ƙirji da wahalar numfashi.

Amma ku tuna,Yin maganin da ya yi nasara zai iya dakatarwa ko rage lalacewar jijiya. Haka kuma zai iya taimakawa wajen rage wasu alamun. Har ma lalacewar jijiya na iya warkewa a hankali akan lokaci.

Akwai abubuwan da ke haifar da cutar POEMS?

A halin yanzu babu wani abu da aka gano yana iya haifar da ciwon POEMS.

Za a iya hana cutar POEMS?

Abin takaici, ba za a iya hana cutar POEMS ba.

Mene ne hasashen mutanen da ke fama da cutar POEMS?

Lafiyarka ta dogara ne akan abubuwa da yawa, ciki har da waɗanne sassan jikinka ne suka kamu da cutar, yadda ake gano cutar da sauri kuma magani ya fara, da kuma yadda kake mayar da martani ga magani.

Yana da mahimmanci a sami magani ga POEMS. Ciwon POEMS na iya zama barazana ga rayuwa idan ba a yi maganinsa ba. A gefe guda kuma, nasarar jiyya da ke lalata ƙwayoyin plasma marasa kyau na iya taimaka maka ka rayu tsawon rai. Bugu da ƙari, jiyya na iya rage alamun cutar da inganta rayuwarka.

Matsakaicin adadin tsira ga yawancin mutanen da ke da WAƘOƘI shine kimanin shekaru 14. Wannan yana nufin cewa kusan rabin mutane suna rayuwa ƙasa da shekaru 14, yayin da sauran rabin suna rayuwa tsawon lokaci. Tsawon rayuwarka ya dogara ne akan takamaiman gogewarka da maganin cutar.

Tambayi likitanka game da makomarka a matsayin wanda ke fama da cutar POEMS.

Yaushe ya kamata ku ga likita game da cutar POEMS?

Idan ka fuskanci wata alama da ke da alaƙa da ciwon POEMS, musamman rauni a hannaye da ƙafafu , ka nemi likita nan da nan.

Waɗanne tambayoyi ya kamata in yi wa likitana game da cutar POEMS?

Za ka iya yin tambayoyi kamar haka:

• Yaya tsananin yanayina yake?
• Waɗanne zaɓuɓɓukan magani nake da su?
• Me ya kamata in yi don rage ko magance illolin da ke tattare da hakan?
• Wadanne ayyukan tallafi ne ake da su a gare ni?
• Shin ina buƙatar ganin likita wanda ya ƙware a fannin matsalolin ƙwayoyin jini don ya jagorance ni?

Yaushe zan iya komawa ga ayyukana na yau da kullun idan ina da cutar POEMS?

Ciwon POEMS na iya shafar ikonka na gudanar da ayyukanka na yau da kullum. Likitanka zai yi maka bayani kan yadda wannan yanayin zai shafi rayuwarka ta yau da kullum.

Shin ciwon POEMS cuta ce ta garkuwar jiki?

POEMS wata cuta ce ta paraneoplastic.Ba cuta ce ta garkuwar jiki ba. Ciwon paraneoplastic tarin alamu ne da ke faruwa sakamakon wata cuta ta rashin lafiya. A cikin POEMS, matsalar da ke faruwa ita ce ƙwayoyin plasma marasa kyau suna samar da furotin M da yawa a cikin jini (cutar ƙwayoyin plasma monoclonal). Alamomin POEMS suna faruwa ne sakamakon ƙwayoyin plasma marasa kyau da kuma furotin M da ke lalata kyallen jiki.

Shin cutar POEMS iri ɗaya ce da cutar myeloma mai yawa?

Ciwon myeloma mai yawa (Multiple myeloma) ciwon daji ne da ke shafar ƙwayoyin plasma. Ciwon POEMS tarin alamu ne da ƙwayoyin plasma marasa kyau ke haifarwa da kuma ƙaruwar furotin na M. Yawan tsira daga ciwon POEMS ya fi tsawon rai na myeloma mai yawa.

Duk da haka, maganin chemotherapy na POEMS da myeloma mai yawa sau da yawa suna kama da juna. Wasu daga cikin alamun kuma suna iya kama da juna.

Ciwon POEMS cuta ce mai sarkakiya. Yana iya ɗaukar likitanka na ɗan lokaci kafin ya tantance cewa ciwon POEMS ne ya haifar da alamominka ba wai wani yanayi ba. Da zarar an gano cutar, yi aiki tare da ƙungiyar likitocinka don tantance waɗanne magunguna ne za su taimaka maka wajen rage alamun. Tambayi likitanka game da ƙungiyoyi ko ƙungiyoyin tallafi waɗanda ke taimaka wa mutane da iyalai da ke fama da cututtuka kamar ciwon POEMS.

Saƙon Ɗauka Gida

To, mun yi magana sosai game da Ciwon POEMS a yau. Abu mafi mahimmanci shine a fahimci cewa wannan yanayi ne mai wuya, amma mai tsanani . Yana iya shafar tsarin jiki da yawa.

• Sunan POEMS ya samo asali ne daga haruffan farko na sunayen Ingilishi na manyan alamomi guda biyar (cututtukan jijiyoyi, faɗaɗa gabobin ciki, matsalolin hormonal, ƙaruwar furotin M, da canjin fata).
• Babban dalilin hakan shine ƙwayoyin plasma marasa kyau da kuma furotin M da suke samarwa.
• Duk da cewa babu cikakken magani, akwai magunguna masu inganci don magance alamun cutar da kuma inganta rayuwar mutane.
• Yana da matuƙar muhimmanci a gano cutar a kuma fara magani da wuri .

Idan kana da ɗaya daga cikin waɗannan alamun, don Allah ka nemi shawarar likita. Kada ka firgita, da cikakken bayani da tallafin likita, za ka iya jure wannan yanayin.

Ciwon POEMS , cututtukan jini, lalacewar jijiyoyi, matsalolin hormonal, furotin M, canje-canjen fata, ƙwayoyin plasma