ʻO ka pilina ma waena o ka maʻi diabetes a me ka maʻi Alzheimer: E kamaʻilio kākou e pili ana i ka maʻi diabetes 'Type 3'

Ke lohe ka hapa nui o kākou i ka huaʻōlelo diabetes, manaʻo mākou he maʻi ia e hoʻopilikia ana i nā pae kō o ke kino, ka puʻuwai, nā puʻupaʻa, a me nā maka. He ʻoiaʻiʻo kēlā. Akā, ua ʻike anei ʻoe, ua ʻike ʻia ma kahi noiʻi hou e hiki i ka maʻi diabetes ke hoʻopilikia pololei i ko kākou lolo a me ka hoʻomanaʻo. Ke hoʻohana nei kekahi mau kauka i kahi inoa hou no kēia maʻi, ʻo ia hoʻi ʻo 'Type 3 Diabetes'. No laila, i kēia lā, e kamaʻilio kākou e pili ana i kēia.

He aha maoli ka maʻi diabetes 'Type 3'?

I ka ʻōlelo maʻalahi, ʻo 'Type 3 diabetes' kahi inoa i hāpai ʻia e kekahi poʻe loea no ka maʻi Alzheimer. ʻO ke kumu, manaʻoʻiʻo lākou ʻo ke kumu nui o kekahi mau ʻano o ka maʻi Alzheimer ʻo ia ka pōʻino e hiki ai i ka maʻi diabetes ke hana i ka lolo i ka hala ʻana o ka manawa.

No ka manawa lōʻihi, ua manaʻo nā kānaka ʻepekema ʻaʻohe pili o ka hormone insulin me ka hana o ka lolo. Akā i kēia manawa ua ʻike mākou ʻaʻole ia ka hihia. Hele pū ka insulin i ko mākou mau hunaola lolo. A he mea nui loa kēia insulin no ko mākou noʻonoʻo a me ka hoʻomanaʻo.

No laila, ke loaʻa ʻole i kou lolo ka insulin lawa, a i ʻole ke hiki ʻole iā ia ke hoʻohana i ka insulin, loaʻa pono ia (kapa mākou i kēia he kū'ē ʻana i ka insulin), hoʻomaka ka hana o kēlā me kēia lā o nā hunaola lolo e hōʻino. ʻO kēia ka mea e hana ʻia ma ka maʻi Alzheimer.

No ke aha lā kēia e hana nei? He aha nā kumu?

Ua hōʻike maopopo ʻia e ka noiʻi ʻana he nui ka pilikia o ka poʻe me ka prediabetes a i ʻole ka maʻi diabetes type 2 i ka loaʻa ʻana o Alzheimer's a me nā dementias ʻē aʻe ma hope o ke ola. ʻO kēia ma muli o kekahi mau kumu.

1. Ka hōʻino a me ka mumū i nā kīʻaha koko

Hoʻonui ka maʻi diabetes i ka pilikia o ka maʻi puʻuwai a me ka hahau. Eia kekahi, ke piʻi aʻe ke kiʻekiʻe o ke kō koko, loaʻa ka mumū i loko o ke kino. ʻAʻole maikaʻi kēia no ko kākou mau kīʻaha koko. Ke hōʻino ʻia nā kīʻaha koko palupalu i loko o ka lolo ma kēia ʻano, hiki iā ia ke hoʻomākaukau i ke ala no ka maʻi Alzheimer.

2. Ka hoʻohaunaele ʻana i ke kamaʻilio ʻana ma waena o nā hunaola nerve

Ke piʻi aʻe ke kiʻekiʻe o ke kō koko, hōʻiliʻili nā puʻupuʻu protein i kapa ʻia ʻo beta-amyloid i loko o ka lolo. Hōʻuluʻulu kēia mau puʻupuʻu a paʻa ma waena o nā hunaola nerve i loko o ka lolo. E like me ke kaʻa ma ke alanui, pale kēia mau puʻupuʻu protein i nā hunaola nerve mai ke kamaʻilio ʻana me kekahi. He hiʻohiʻona koʻikoʻi kēia o ka maʻi Alzheimer.

3. Ka huikau ʻana o ka protein Tau

E noʻonoʻo i ko kākou lolo he ʻōnaehana o nā paipu liʻiliʻi (microtubules) e lawe ana i nā meaʻai i mua a i hope i loko o nā hunaola nerve. ʻO kahi protein i kapa ʻia ʻo tau e hana ma ke ʻano he 'kiaʻi' e mālama i kēia ʻōnaehana o nā paipu i ke ʻano a mai ka hele hewa ʻana. I loko o ka lolo o kekahi me ka maʻi Alzheimer, ua hihia kēia protein tau. A laila ua ālai ʻia ka ʻōnaehana o nā paipu, ʻaʻole hiki i nā hunaola ke lawe i kā lākou mea e pono ai, a make nā hunaola. Ua ʻike kekahi mau noiʻi he nui aku kēia mau protein tau i hihia i loko o ka lolo o ka poʻe me ka maʻi diabetes.

4. Ke kū'ē ʻana i ka insulin

ʻO kēia ka puʻuwai o ke kumumanaʻo o ka 'diabetes Type 3'. E like me nā cell i loko o ke kino, ke pane ʻole nā ​​cell lolo i ka insulin, ʻaʻole loaʻa i kēlā mau cell ka ikehu (wahie) a lākou e pono ai. A laila ua hōʻino ʻia ka hana o ka lolo. Eia kekahi, hoʻonui ka pale ʻana o ka insulin i loko o ka lolo i kahi kūlana ʻino i kapa ʻia ʻo oxidative stress.

He aha nā hōʻailona o kēia maʻi?

Ua like nā hōʻailona e pili ana i ka manaʻo o ka 'Type 3 Diabetes' me nā hōʻailona o ka maʻi Alzheimer. Hiki ke ʻike ʻia kēia mau mea i nā pae mua.

E aʻo kākou e pili ana i ka hōʻoia ʻana a me ka mālama ʻana.

E like me kā mākou i ʻōlelo ai ma mua, ʻaʻohe hōʻailona kūhelu no ka maʻi diabetes type 3, no laila ʻaʻole hiki i ke kauka ke hana i kahi hoʻāʻo e hōʻoia i ia mea. Eia nō naʻe, inā pilikia ʻoe me kou hoʻomanaʻo, e hoʻāʻo kāu kauka iā ʻoe no ka dementia.

Hiki i kēia ke komo pū me nā nīnau no ke kūlana noʻonoʻo, nā scan lolo (MRI a i ʻole CT scan), a i kekahi manawa nā hoʻāʻo wai o ka spinal.

I ka wā e pili ana i ka lāʻau lapaʻau, ʻaʻohe lāʻau lapaʻau kūikawā no ka 'Diabetes Type 3'. Akā aia ʻelua mau mea nui loa hiki iā ʻoe ke hana:

1. Inā loaʻa iā ʻoe ka maʻi diabetes, e kāohi pono iā ia. He mea nui e hoʻohana pono i ka lāʻau lapaʻau i kuhikuhi ʻia e kāu kauka a kāohi i kou pae kō koko.

2. E kiʻi i nā lāʻau lapaʻau o kēia manawa no ka maʻi Alzheimer. ʻOiai ʻaʻole hiki i kēia mau lāʻau lapaʻau ke ho'ōla piha i ka maʻi, hiki iā lākou ke kōkua i ka hoʻolohi ʻana i ka wikiwiki o ka ʻino ʻana o nā hōʻailona.

Ua hōʻike pū kekahi mau noiʻi e hiki i kekahi mau lāʻau lapaʻau maʻi diabetes, e like me ka metformin a me ka pioglitazone, ke hōʻemi i ka pilikia o ka hoʻomohala ʻana i ka dementia ma hope o ke ola. Ke hoʻomau nei ka noiʻi hou aku.

Pehea e hiki ai iā ʻoe ke pale i ke olakino o kou lolo a hōʻemi i kēia pilikia?

I mea e palekana ai mai kēia pilikia, aia kekahi mau mea nui loa e hiki iā kākou ke hoʻohui i ko kākou nohona. He mea maikaʻi loa kēia no ke olakino o kou lolo, a me kou kino holoʻokoʻa.

• E noho hana: E hoʻoikaika kino no 30 mau minuke i ka lā, ma ka liʻiliʻi he 5 mau lā o ka pule. E koho i kahi mea āu e makemake ai. Hiki ke hele wāwae, hula, a paikikala paha.
• E pale i ka puhipaka: Inā ʻoe e puhipaka, e noi i kāu kauka no ke kōkua e haʻalele.
• E mālama i ke kaumaha olakino: E ʻai i nā huaʻai, nā mea kanu, nā palaoa piha (e like me ka laiki ʻeleʻele), nā ʻiʻo momona ʻole, a me nā huahana waiū momona haʻahaʻa. E hōʻemi i ke kō a me nā momona momona.
• E mālama i kou koko: Inā ua kuhikuhi kāu kauka i ka lāʻau lapaʻau, e lawe pono e like me ke kauoha.
• Hiamoe maikaʻi: E hoʻāʻo e loaʻa i 7-8 mau hola o ka hiamoe maikaʻi i kēlā me kēia lā.
• E launa pū: E hoʻolilo i ka manawa me nā hoaaloha a me ka ʻohana. ʻAʻole maikaʻi ka mehameha a me ka noho kaʻawale no ka lolo.
• E aʻo i nā mea hou: ʻO nā mea e like me ke aʻo ʻana i kahi ʻōlelo hou, kahi mea kani, a i ʻole ka hoʻoponopono ʻana i nā puʻupuʻu e kūkulu i nā pilina hou ma waena o nā hunaola o ka lolo.