Ua lohe paha ʻoe i ka Viagra , ʻeā? E like me ka ʻike o ka hapa nui o ka poʻe, hoʻohana ʻia kēia lāʻau lapaʻau e mālama i nā kūlana e like me ka erectile dysfunction. Akā, e kahaha paha ʻoe inā haʻi aku kekahi iā ʻoe e hiki i kēia lāʻau lapaʻau ke kōkua i ka pale ʻana iā Alzheimer's , kahi maʻi koʻikoʻi e hoʻoulu ai i ka nalowale o ka hoʻomanaʻo. Ua nui nā kamaʻilio e pili ana i ia mea ma ke ao lapaʻau i kēia mau lā. No laila e ʻike hou kākou e pili ana i ia mea i kēia lā.
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He aha maoli ka maʻi o Alzheimer?
I ka ʻōlelo maʻalahi ʻana i kēia, e noʻonoʻo kākou i ko kākou lolo e like me ke kūlanakauhale hana nui. Holo nā ʻiole nerve i kapa ʻia ʻo neurons a puni kēia kūlanakauhale e lawe i ka ʻike i mua a i hope. Ke ulu ka maʻi Alzheimer , kū mai ʻelua mau pilikia ma kēia kūlanakauhale.
1. Nā Pāka Amyloid: Ua like kēia me nā puʻu ʻōpala e hōʻiliʻili ana i nā kūlanakauhale. Hoʻopilikia kēia mau puʻu ʻōpala i ke kamaʻilio ʻana ma waena o nā hunaola nerve.
2. Nā Tau Tangles: I loko o nā pūnaewele nerve, aia nā microtubules e lawe ana i ka ʻike. Kōkua kahi protein i kapa ʻia ʻo Tau i ka mālama ʻana i kēia mau ala ma kahi. Eia nō naʻe, i ka maʻi Alzheimer, loli kēia protein tau a lilo i mea like me ka pōpō kaula i ulana ʻia . Pale kēia i nā ala i loko o nā pūnaewele a pale i nā meaʻai mai ka neʻe ʻana a puni.
I ka ʻōlelo maʻalahi, ʻo kēia mau puʻu o nā ʻōpala a me nā pōpō kaula i hiolo ʻia e pale aku i nā ʻāpana lolo mai ke kamaʻilio ʻana me kekahi i kekahi, hoʻonele iā lākou i nā meaʻai, a ma hope e make ai lākou. ʻO kēia ke kumu o nā hōʻailona e like me ka nalowale o ka hoʻomanaʻo a me ka huikau.
No laila pehea e kūpono ai ʻo Viagra i kēia?
ʻO Viagra, a i ʻole ka lāʻau sildenafil , he vasodilator maoli ia e hoʻonui ai i nā kīʻaha koko a hoʻomaikaʻi i ke kahe koko . Ua ʻike nā kānaka noiʻi he haʻahaʻa nā pae o kēlā protein tau tangle i loko o ko lākou lolo i ka poʻe e hoʻohana ana i ka lāʻau.
Hōʻike kēia i ka wā e maikaʻi ai ke kahe ʻana o ke koko i ka lolo , loaʻa i nā ʻāpana ka meaʻai maikaʻi aʻe, kahi e hōʻemi ai i ka hoʻokumu ʻia ʻana o kēia mau protein tau. ʻO kēia ka manaʻolana no ka pilina ma waena o Viagra a me ka maʻi Alzheimer.
Akā, aia kekahi mea nui loa e hoʻomaopopo ai ma ʻaneʻi. Ua hōʻike wale kēia mau haʻawina ua emi iki ka pilikia o ka poʻe i hoʻohana i ka Viagra ma mua o ka loaʻa ʻana o ka maʻi Alzheimer. ʻO ke ʻano kēia, ʻaʻole i hōʻoia ʻia e ho'ōla i kahi mea i loaʻa mua iā Alzheimer.
No laila hiki ke lawe ʻia ʻo Viagra ma ke ʻano he lāʻau lapaʻau no ka maʻi o Alzheimer?
ʻO ka pane pōkole i kēia, "ʻAʻole i kēia manawa."
ʻAʻole i ʻōlelo ʻia e nā kauka no ka pale ʻana a i ʻole ka mālama ʻana i ka maʻi Alzheimer, no ka mea, pono ka noiʻi hohonu hou aku, a i ʻole nā hoʻokolohua lapaʻau.
E noʻonoʻo i ka maʻi Alzheimer ma ke ʻano he puzzle nui. Hiki i ka Viagra ke hoʻoponopono i hoʻokahi ʻāpana o ka puzzle. ʻO ia hoʻi, ka hoʻomaikaʻi ʻana i ke kahe koko i ka lolo. Akā, ʻo nā ʻāpana ʻē aʻe, e like me ka kaohi ʻana i nā protein amyloid a me tau a me ka hōʻemi ʻana i ka mumū i loko o ka lolo, pono nā lāʻau lapaʻau kaʻawale.
No laila, ʻoiai ʻo Viagra kekahi ʻāpana o kēia papa hana lapaʻau i ka wā e hiki mai ana, ʻaʻole ia he "pill magic" e hoʻoponopono i nā mea āpau.
Nā hopena ʻaoʻao a me nā pilikia o ka hoʻohana ʻana iā Viagra
E like me nā lāʻau lapaʻau āpau, hiki iā Viagra ke hana i nā hopena ʻaoʻao. Hiki iā ia ke launa pū me nā lāʻau lapaʻau ʻē aʻe āu e lawe nei a hoʻoulu i nā pilikia koʻikoʻi.
Mai hoʻohana i kēia ʻano lāʻau lapaʻau me ka ʻole o ka ʻōlelo aʻoaʻo a ke kauka no kekahi kumu.
| Nā hopena ʻaoʻao maʻamau |
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He aha ke ʻano o ka 'Drug Repurposing'?
He manaʻo hoihoi loa kēia. I ka ʻōlelo maʻalahi, ʻo ke 'Drug Repurposing' ka manawa e hōʻike ai nā noiʻi he pono nō hoʻi kahi lāʻau i ʻae ʻia e mālama i hoʻokahi maʻi no kahi maʻi ʻokoʻa loa, a hoʻohana ʻia ka lāʻau no kēlā maʻi hou.
ʻO ka pōmaikaʻi o kēia, ʻo ia ka mālama ʻana i ka manawa he 10-15 mau makahiki a me ke kumukūʻai kiʻekiʻe o ka loaʻa ʻana o kahi lāʻau hou. Ke hana nei kekahi mea like me Viagra.
Akā ma mua o ka hiki ke ʻōlelo ʻia ʻo Viagra no ka maʻi o Alzheimer, pono nā kānaka noiʻi e ʻimi i nā pane i kēia mau nīnau:
- He palekana anei kēia lāʻau lapaʻau no ka poʻe ʻelemakule?
- He aha ka lāʻau kūpono no ka maʻi o Alzheimer?
- He aha nā hopena ʻaoʻao kikoʻī e ʻike ai ka poʻe ʻelemakule i ka wā e hoʻohana ai i kēlā mahele lāʻau?
E lōʻihi ana ka manawa e hōʻoia ai i kēia mau mea a pau.
Leka Lawe-Home
- Ua hāpai ka noiʻi mua i ka manaʻolana e hiki paha i ka lāʻau Viagra ke hōʻemi i ka pilikia o ka maʻi Alzheimer.
- Ua manaʻo ʻia kēia ma muli o ka hoʻomaikaʻi ʻana o ke kahe koko i ka lolo a me ka hoʻemi ʻana o ka hōʻiliʻili ʻana o ka protein tau.
- Eia nō naʻe, ʻaʻole ʻōlelo ʻia ʻo Viagra i kēia manawa he lāʻau lapaʻau a pale paha no ka maʻi Alzheimer. Pono ka noiʻi hou aku.
- ʻO ka mea nui loa: Mai lawe i kekahi lāʻau lapaʻau me ka ʻole o ke kūkākūkā ʻana me kāu kauka. Hiki ke lilo i mea weliweli loa. E kūkākūkā mau me kāu kauka no nā hopohopo olakino.
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