He aha ka AA Amyloidosis? E aʻo maʻalahi kākou e pili ana iā ia!

Ua noʻonoʻo paha ʻoe i ka mea e hiki ke hana inā hele hewa kekahi mau protein i loko o ko kākou kino? I kēia lā e kamaʻilio mākou e pili ana i kekahi ʻano maʻi kakaʻikahi akā koʻikoʻi e makaʻala. ʻO ia ka AA Amyloidosis.

He aha ka AA Amyloidosis? E hoʻomaopopo maʻalahi kākou!

I ka ʻōlelo maʻalahi, ʻo AA Amyloidosis kekahi ʻano o kahi hui nui o nā maʻi i kapa ʻia ʻo amyloidosis. I kēia manawa ke nīnau nei paha ʻoe, 'He aha kēia amyloidosis?' ʻĀ, he ʻano protein ko ko mākou kino i kapa ʻia ʻo amyloid. Loaʻa i kēia mau protein kahi ʻano ʻekolu-dimensional kikoʻī (ʻano 3D). Pēlā lākou e hana ai. Eia naʻe, i kekahi manawa hoʻololi kēia mau protein i ko lākou ʻano, hihia e like me ka pōpō o ke kaula, a hana i nā olonā liʻiliʻi (fibrils). ʻO kēia ka mea a mākou e kapa nei he 'nā waihona amyloid'. ʻO ka hōʻiliʻili ʻana o kēia mau waihona i loko o kā mākou mau ʻōkana a me nā ʻiʻo like ʻole ua kapa ʻia ʻo amyloidosis.

I loko o ka AA amyloidosis, piʻi nui ka pae o ka protein serum A i loko o ke koko ma muli o ka mumū nui i loko o ko mākou kino. Inā loaʻa iā ʻoe kahi maʻi lōʻihi a i ʻole ka maʻi mumū, hiki ke piʻi aʻe kēia pae protein serum A. Ma kekahi ʻano, he pilikia koʻikoʻi ka AA amyloidosis o kēia mau maʻi mumū. Hoʻōla nā kauka iā ia ma ka mālama ʻana i ka maʻi mumū ma lalo.

Pehea ka hopena o ka AA amyloidosis i ko mākou kino?

I kēia manawa, e nānā kākou pehea e hoʻopilikia ai kēia AA amyloidosis i ko mākou kino. Hiki iā ia ke hōʻino nui i ko mākou mau puʻupaʻa . ʻAʻole wale ia, akā hiki iā ia ke hōʻino i ke akepaʻa, ka spleen, ka ʻōpū, a me nā ʻōpū. Kākaʻikahi ka hoʻopilikia ʻana i ka puʻuwai. ʻO kekahi mea ʻē aʻe, hiki i kēia maʻi ke hoʻopilikia i ka nui o ka protein i loko o kou mimi a me ka pae cholesterol i loko o kou koko.

He kūlana make anei kēia?

ʻAe, he pilikia koʻikoʻi maoli kēia. Inā ʻaʻole mālama pono ʻia ka AA Amyloidosis, hiki ke make . E hoʻomanaʻo, ua ʻōlelo wau ua hana ʻia kēia e kahi maʻi e hoʻoulu ai i ka mumū lōʻihi. No laila, ke mālama nā kauka i ka maʻi kumu, mālama pū lākou i ka AA amyloidosis. No laila, ʻaʻohe mea e hopohopo ai, akā ʻo ka mea nui loa, ʻo ia ka ʻike mua ʻana a loaʻa ka lāʻau lapaʻau .

ʻO wai ka mea i loaʻa ka AA amyloidosis?

Inā ʻoe e noʻonoʻo e pili ana i ka mea hiki ke hoʻomohala i kēia, ʻo kēlā me kēia mea i loaʻa i kahi maʻi mumū mau loa e pilikia ana i ka hoʻomohala ʻana i ka AA amyloidosis . ʻO ia hoʻi, inā loaʻa iā ʻoe kēlā maʻi, he mea maikaʻi ke makaʻala iki i kēia.

He aha ke kumu o ka amyloidosis AA?

E nānā pono kākou i ke kumu o kēia. ʻO ka amyloidosis AA kahi ʻano amyloidosis. Ua kapa nā kauka i kēia amyloidosis he "protein misfolding disorder." E noʻonoʻo e pili ana i ia mea, ʻo kā mākou mau protein he mau mole lōʻihi me nā ʻano ʻekolu-dimensional (3D) kūikawā. Hana nui kēia mau protein i loko o ko mākou kino - mai ka hāʻawi ʻana i ka ikehu, a hiki i ke kaulike ʻana i nā wai, a hiki i ke kōkua ʻana i ka pale ʻana, a hiki i ka hāʻawi ʻana i ke ʻano o ke kino, a hiki i ka hoʻoneʻe ʻana i nā mea a puni, a hiki i ka kaohi ʻana i nā kaʻina hana o ke kino, a pēlā aku.

ʻO ka maʻamau, hoʻoneʻe ʻia kēia mau protein mai ke koko ke pau kā lākou hana. Eia nō naʻe, i nā maʻi kahi e pelu pono ʻole ai kēia mau protein, hoʻololi ke ʻano o nā protein a lawe i nā ʻano ʻē ʻole i hiki ʻole i ke kino ke hoʻohana a wehe paha. I ka AA amyloidosis, hui pū kēia mau protein ʻē a hana i nā 'waihona amyloid', a i ʻole 'fibrils', i loko o ko kākou mau kino.

Ua ʻike ʻia e nā noiʻi hou kekahi mau kūlana e hiki ai ke hoʻoulu i ka amyloidosis AA. ʻO kēia mau mea kekahi mau ʻano maʻi kanesa koko, nā maʻi bacteria e like me nā ʻōpū maʻi mau, nā maʻi rheumatic e like me ka rheumatoid arthritis, a i ʻole nā ​​maʻi ʻōpū mumū e like me ka maʻi Crohn a i ʻole ka ulcerative colitis. I kekahi manawa, hiki ke hana ʻia e nā kūlana hoʻoilina e like me nā syndromes fever periodic e like me ka familial Mediterranean fever.

He aha nā hōʻailona o ka amyloidosis AA?

ʻAe, e nānā kākou i nā hōʻailona o ka AA amyloidosis. ʻO ka hapa pinepine, hoʻopilikia ia i nā puʻupaʻa. Hiki iā ia ke hoʻopilikia i nā ʻōpū e like me ke akepaʻa, ka spleen, a me ka ʻōpū. E nānā inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona:

• Ka pehu ʻana ma nā wāwae a i ʻole nā ​​kuʻekuʻe wāwae . Hiki i kēia ke lilo i hōʻailona o ka pilikia o ka puʻupaʻa. Hiki nō hoʻi ke lilo i hōʻailona o ka maʻi puʻupaʻa mau loa.
• Mimi huʻa a huʻa paha.
• ʻEmi ka hoʻopuka ʻana o ka mimi ma mua o ka maʻamau.
• Ka maʻi pākī mau loa.
• Ka hoʻonui ʻia ʻana o ka puʻupaʻa.
• Ka hoʻonui ʻia ʻana o ke akepaʻa.
• Ke koko haʻahaʻa.
• Ka luaʻi a me ka luaʻi.

Pehea e ʻike ai nā kauka i ka AA amyloidosis?

Pehea e ʻike ai nā kauka i kēia maʻi? Hana lākou i kekahi mau hoʻokolohua. ʻO ka mea nui he biopsy.

• ʻO ka biopsy "Fat pad" : Pili kēia i ka lawe ʻana i kahi momona liʻiliʻi mai lalo o ka ʻili o ka ʻōpū a nānā iā ia. He mea maʻalahi loa ia.
• ʻO ka biopsy kino : Lawe ʻia kahi hāpana ʻiʻo liʻiliʻi mai kahi ʻano i manaʻo ʻia ua hoʻopilikia ʻia a nānā ʻia.

Eia kekahi, hiki ke hana ʻia nā hoʻokolohua ʻē aʻe e hōʻoia inā he ʻano amyloidosis ʻē aʻe kāu i kapa ʻia ʻo "AL amyloidosis." Ma muli o ka like like o nā hōʻailona o AL amyloidosis a me AA amyloidosis, ʻoi aku ka koʻikoʻi o ka AL amyloidosis a me ka holomua wikiwiki .

Pehea e mālama ʻia ai ka amyloidosis AA?

I kēia manawa, e nānā kākou i nā lāʻau lapaʻau no kēia. Hoʻokumu ʻia ka AA amyloidosis e kahi maʻi mumū lōʻihi e hoʻoulu ai i nā protein maʻamau ʻole e hōʻiliʻili i loko o kou mau kino. No laila, mālama nā kauka iā ia ma ka mālama ʻana i ke ʻano mumū ma lalo . Ke mālama ʻoe i ke ʻano ma lalo a hoʻēmi i ka mumū, e kāohi ʻia ke ʻano AA amyloidosis. I ka emi ʻana o ka pae mumū, e emi mālie ana nā hōʻailona.

Aia kekahi mau lāʻau lapaʻau i loaʻa i kēia manawa no ka mālama ʻana i ka AA amyloidosis. Ke hoʻomau nei nā kauka a me nā mea noiʻi i ka ʻimi ʻana i nā lāʻau lapaʻau hou. No ka laʻana, ke noiʻi nei lākou i nā ala e wehe ai i kēia mau fibrils amyloid mai ke koko ma mua o ko lākou hōʻiliʻili ʻana i loko o nā ʻōpū, a ke noiʻi nei hoʻi lākou i nā antibodies i hana ʻia i ka lab e hiki ke kuhikuhi a wehe i nā fibrils amyloid i hōʻiliʻili mua ʻia i loko o nā ʻōpū.

Hiki ke pale ʻia ka AA amyloidosis?

Hiki ke pale ʻia kēia? ʻOiaʻiʻo, inā loaʻa iā ʻoe kahi maʻi mumū mau loa e like me ka rheumatoid arthritis, hiki iā ia ke hoʻonui i kekahi mau protein i loko o ke koko a hana i ka AA amyloidosis. No laila, ʻo ke ala wale nō e pale aku ai i kēia, ʻo ia ka loaʻa ʻana o ka lāʻau lapaʻau koke a kūpono no ka maʻi mumū mau loa āu e loaʻa nei .

Hiki ke ho'ōla ʻia ka AA amyloidosis?

ʻAe, hiki ke ho'ōla ʻia. Hoʻōla nā kauka i ka AA amyloidosis ma ka mālama ʻana i ke kūlana mumū i hoʻokumu ʻia ai. E like me nā maʻi he nui, ʻo ke ala maikaʻi loa e hoʻokele ai i ka AA amyloidosis, ʻo ia ke ʻike i ka maʻi a hoʻomaka i ka mālama ʻana i ka wā hikiwawe loa .

Pehea wau e mālama ai iaʻu iho?

Inā loaʻa iā ʻoe ka AA amyloidosis, ʻo ke ala maikaʻi loa e mālama ai iā ʻoe iho, ʻo ia ke hana pū me kāu kauka e mālama pono i ke kūlana mumū i hoʻokumu ʻia ai. Ua ʻike nā kānaka noiʻi i kekahi mau maʻi a me nā kūlana e hoʻoulu ai i ka mumū lōʻihi e pili ana i ka AA amyloidosis. E nīnau i kāu kauka pehea i hoʻokumu ai kou kūlana i ka AA amyloidosis a pehea lākou e mālama ai i kēlā kūlana mumū.

I ka ʻōlelo maʻalahi, he pilikia kakaikahi ka AA amyloidosis, akā he koʻikoʻi, o nā maʻi mumū maʻamau a i ʻole nā ​​​​kūlana. ʻO ka mea pōmaikaʻi, hiki i nā kauka ke mālama iā ia ma ka mālama ʻana i ke kūlana kumu. I ka manawa pinepine, ʻo nā hōʻailona o ka AA amyloidosis e like me nā pilikia maʻamau āu i maʻa ai me kāu maʻi mumū. Akā, e like me nā maʻi koʻikoʻi ʻē aʻe, ʻoi aku ka nui o ka mālama ʻana o nā kauka inā loaʻa koke.Inā ʻike ʻoe i kekahi mau loli a i ʻole nā ​​​​hōʻailona hou i kou ʻāʻī, e haʻi koke i kāu kauka . E nānā lākou i kāu mau hōʻailona a wehewehe i ko lākou manaʻo.

No laila, he aha nā mea nui e pono ai kākou e hoʻomanaʻo mai kēia moʻolelo?

He huaʻōlelo weliweli iki ka AA Amyloidosis, akā he mea nui loa ia e hoʻomaopopo pono i ia mea.

E hoʻomanaʻo, hana pinepine kēia ma ke ʻano he pilikia o kahi maʻi mumū lōʻihi ʻē aʻe.

• Inā loaʻa iā ʻoe kahi maʻi mumū mau loa, e like me ka rheumatoid arthritis, he mea nui e ʻimi i ka lāʻau lapaʻau kūpono .
• Inā loaʻa iā ʻoe nā hōʻailona hou, e like me nā pilikia o nā puʻupaʻa (pehu ʻana i nā wāwae, nā loli i ka mimi), ka maʻi diarrhea mau, a i ʻole ka hoʻonui ʻia ʻana o ke akepaʻa a i ʻole ka spleen, e hoʻomaopopo i kāu kauka .
• Inā ʻike ʻia a mālama ʻia ka AA amyloidosis i ka wā mua, hiki ke hoʻokō ʻia nā hopena maikaʻi . ʻO ke kumu nui o ka lāʻau lapaʻau, ʻo ia ka mālama ʻana i ka maʻi mumū ma lalo.
• Mai makaʻu, akā e makaʻala . E kamaʻilio ākea me kāu kauka, e haʻi iā lākou i kou mau pilikia. E kōkua lākou iā ʻoe.

No laila, ke lana nei ko mākou manaʻo he mea pono kēia ʻike iā ʻoe. E noho olakino!

ʻAmyloidosis , AA amyloidosis, protein, mumū, maʻi puʻupaʻa, maʻi mau, rheumatoid arthritis