He aha ka Apoptosis? He ala kupaianaha no ka make ʻana o nā pūnaewele i loko o ko kākou kino!

Ua noʻonoʻo paha ʻoe i ka mea e hana ʻia i nā ʻāpana o ko kākou kino, ʻoiai ke ʻelemakule a hōʻino ʻia paha? ʻO ka ʻoiaʻiʻo, he hiki kupaianaha ko ko kākou kino ke ʻike i kēia mau ʻāpana a hoʻopau iā lākou ma ke ʻano maʻamau. ʻO ia ka mea a kākou e kapa nei he apoptosis . I ka ʻōlelo maʻalahi, he kaʻina hana kēia o ka make ʻana o nā ʻāpana a ke kino e hoʻolālā a kāohi ai, e like me ka 'make ʻana o nā ʻāpana i hoʻolālā ʻia'.

No ke aha he mea nui kēia mea i kapa ʻia ʻo apoptosis iā mākou?

E noʻonoʻo, ke ʻelemakule nei kekahi mau pūnaewele i loko o ko kākou kino, a i ʻole e hōʻino ʻia kā lākou DNA. Inā hoʻomau kēia mau pūnaewele i ke ola ʻana i loko o ke kino, hiki iā lākou ke hoʻomau i ka māhele ʻana a me ka hoʻonui ʻana me ke kāohi ʻole ʻia, e hoʻoulu ai i nā maʻi weliweli e like me ke kanesa. ʻO kēia kaʻina hana i kapa ʻia ʻo apoptosis e kōkua iā mākou e pale aku i ia mau pilikia.

Ua like kēia me ka hoʻolei ʻana i nā lako kahiko a haki i loko o ka hale. E like me ka loaʻa ʻana o kēlā lako e hiki ai ke hoʻopilikia i ka hale, ʻo ka loaʻa ʻana o kēia mau ʻāpana i hōʻino ʻia i loko o ko mākou kino hiki ke hoʻoulu i nā pilikia. No laila, ʻo ka apoptosis kahi mea nui e kōkua ai i ka mālama ʻana i ko mākou kino i ke olakino.

Akā, pono e holo nā mea āpau e like me ka hoʻolālā. Inā hewa kekahi mea i kēia kaʻina hana apoptosis, inā paha he nui loa nā cell e make ana a inā ʻaʻole make nā cell e pono e make ana, hiki i kēlā ke hana i nā pilikia.

• Inā nui loa ka apoptosis, hiki iā ia ke luku i nā ʻāpana olakino e pono ai ko kākou kino. No ka laʻana, ʻike ʻia kēia ʻano ma nā maʻi e like me ka maʻi Alzheimer.
• Inā ʻaʻole hana pono ka apoptosis (ua hoʻemi ʻia): Noho nā ʻāpana i hōʻino ʻia a haki i loko o ke kino, kahi e hoʻomaka ai lākou e māhele a hoʻonui me ke kāohi ʻole. Hiki i kēia ke alakaʻi i nā maʻi e like me ke kanesa.

Hiki paha iā ʻoe ke hoihoi i ke aʻo ʻana e pili ana i ka apoptosis no ka mea ua ʻike ʻia ʻoe a i ʻole kekahi āu i ʻike ai me ia. He mea maʻamau ke noʻonoʻo pehea e pili ai kēia mau kaʻina hana liʻiliʻi i loko o nā cell i hiki ke ʻike wale ʻia me kahi microscope i nā hōʻailona a mākou e ʻike ai. Eia nō naʻe, hiki i ka hoʻomaopopo ʻana i ka apoptosis ke kōkua iā ʻoe e hoʻomaopopo i ke 'kumu' ma hope o kāu hōʻailona. Hiki i kēia ʻike ke kōkua iā ʻoe e kamaʻilio me kāu kauka e pili ana i kou kūlana a me nā koho lapaʻau.

He aha ka mea e hana maoli me ka apoptosis? He aha kona kumu?

He hana koʻikoʻi ka Apoptosis i ko kākou kino. Hoʻomaka ia ma mua o ko kākou hānau ʻia ʻana. E noʻonoʻo e pili ana i ia mea, i ka wā e ulu ana kahi fetus i loko o ka ʻōpū, no ka laʻana, i mea e hana pono ai nā manamana lima, pono kekahi o nā cell ma waena e make i ka manawa kūpono. ʻO ia ka mea e kōkua ai ka apoptosis.

ʻOiai ma hope o ko kākou hānau ʻana, hana ka apoptosis i nā hana koʻikoʻi he nui:

• Pono e hoʻololi mau ʻia nā ʻāpana a me nā ʻiʻo kahiko o ko kākou kino me nā mea hou. Kōkua ka apoptosis i kēia.
• Kōkua ia i kā mākou ʻōnaehana pale e hakakā i nā maʻi like ʻole.
• Ua hōʻino ʻia,Hoʻopau ʻia nā pūnaewele i hiki ʻole ke hana hou ʻia mai ke kino.
• Pale ia i nā pūnaewele i hōʻino ʻia mai ka hoʻonui ʻana me ke kāohi ʻole.
• Kōkua i ka mālama ʻana i ke kaulike (`(Homeostasis)`) i loko o nā ʻiʻo o ke kino.

Pehea e hana ai kēia mea i kapa ʻia ʻo apoptosis?

He hana paʻakikī kēia, akā ma nā ʻōlelo maʻalahi, penei ka hana ʻana. Hoʻomaka kekahi mau protein kūikawā i loko o ko kākou kino i kēia kaʻina hana apoptosis. ʻO kahi laʻana he protein i kapa ʻia ʻo `(p53 protein).` Ua kapa ʻia hoʻi kēia he ``tumor suppressor protein'' no ka mea kōkua ia i ka hoʻōki ʻana i nā cell mai ka māhele ʻana me ke kāohi ʻole ʻia, e like me nā cell cancer.

Eia ke ʻano o ka hana ʻana o ka protein `p53`:

1. ʻO ka mea mua, hoʻāla kēia protein i nā "genes" e mālama ana i ka ʻike i loko o ko kākou kino a hoʻāʻo e hoʻoponopono i nā cell me ka "DNA" i hōʻino ʻia.

2. Eia nō naʻe, inā nui loa ka pōʻino e hiki ʻole ke hoʻoponopono, ʻaʻole e ʻae kēlā protein i kēlā cell e māhele a hoʻonui paha.

3. Akā, hoʻouna kēlā protein i kahi hōʻailona, ​​"ʻAe, i kēia manawa pono kēia cell e hoʻomaka i ke kaʻina hana apoptosis."

Ke hoʻomaka ka apoptosis, hana ʻia kekahi mau loli kemika, a haki ke kelepona i nā ʻāpana liʻiliʻi. A laila, hoʻouna ke kelepona make i kahi hōʻailona i nā kelepona ʻē aʻe i kapa ʻia ʻo phagocytes (he ʻano kelepona koko keʻokeʻo, e like me nā mea hōʻiliʻili ʻōpala o ko mākou kino), me ka ʻōlelo ʻana, "E hele mai a ʻai i kēia mau ʻāpana oʻu." I ka manawa like, hoʻouna ke kelepona make i nā hōʻailona i nā ʻiʻo a puni e kōkua i ka hōʻemi ʻana i ka mumū a ho'ōla wikiwiki. Maikaʻi loa, ʻeā?

He mea weliweli anei ka apoptosis nui?

ʻAe, ʻoiaʻiʻo nō. Inā nui loa ka apoptosis, hiki i nā ʻāpana olakino e pono ai ko kākou kino ke make. Ua pili kēia make nui o nā ʻāpana i ka ulu ʻana o nā maʻi he nui. ʻO kekahi o kēia mau maʻi:

• ʻO ka maʻi Alzheimer (ka maʻi Alzheimer)
• ʻO ka maʻi o Huntington (ka maʻi o Huntington)
• ʻO ka maʻi ALS (Amyotrophic lateral sclerosis (ALS))
• ʻO ka maʻi Parkinson (ka maʻi Parkinson)
• `(AIDS)` (AIDS)
• ʻO ka maʻi ulcerative colitis
• `(ʻO ka rumatika)` (ʻO ka rumatika)

I loko o ia mau kūlana, kū mai nā hōʻailona ma muli o ka luku ʻia ʻana o nā pūnaewele e pono ai ke kino.

He aha ka mea e hana ʻia inā ʻaʻole hana pono ka apoptosis (ua hoʻemi ʻia)?

E like me kā mākou i kamaʻilio ai ma mua, he mea nui ka apoptosis no ka hoʻopau ʻana i nā cell i hōʻino ʻia, a i ʻole no ka hoʻōki ʻana i ka ulu ʻana o nā cell i kāohi ʻole ʻia. No laila, inā ʻaʻole hana pono kēia, ʻo ia hoʻi , inā ʻaʻole lawa ka apoptosis, e noho kēlā mau cell maikaʻi ʻole i hōʻino ʻia i loko o ke kino a hoʻomaka e māhele a hoʻonui me ke kāohi ʻole ʻia.

Ua like kēia me ka nāhelehele. Inā ʻaʻole i kāohi pono ʻia, e laha koke ia a hoʻopau i ka māla holoʻokoʻa.

ʻO kēia hoʻonui ʻana o nā cell maʻamau ʻole e alakaʻi i ka maʻi kanesa a me nā maʻi autoimmune.Hiki ke loaʻa nā pilikia olakino koʻikoʻi.

He aha ke kuleana o ka apoptosis i ka mālama ʻana i nā maʻi?

Ua ʻike nā kānaka noiʻi ua pili nā loli i ke kaʻina hana apoptosis i ka ulu ʻana o kekahi mau maʻi. No laila ke ʻimi nei lākou i nā lāʻau lapaʻau e hiki ke hoʻōki i ka apoptosis ke nui loa, a hoʻoulu paha iā ia ke pono .

E noʻonoʻo, i kekahi manawa ke hoʻōki nei kekahi mau protein i loko o ko kākou kino i ka apoptosis i ka wā e pono ai ke hana. A laila hiki i nā cell i hōʻino ʻia ke hoʻomau a ulu i nā puʻupuʻu kanesa. Ke ʻimi nei nā kānaka noiʻi i nā lāʻau lapaʻau e hiki ke hoʻōki i ka hana o kēia mau protein. A laila hiki ke hana pono ʻia ka apoptosis, a ua luku ʻia kēlā mau cell maikaʻi ʻole.

Aia kekahi mau hihia ʻē aʻe kahi e makemake ai mākou e hoʻolohi iki i ke kaʻina hana apoptosis i hiki ai iā mākou ke pale i nā ʻāpana olakino a mākou e pono ai mai ka make ʻana.

ʻO nā lāʻau lapaʻau e kāohi ana i ka apoptosis ma kēia ʻano e kōkua paha i ka mālama ʻana i nā maʻi he nui i ka wā e hiki mai ana. Hiki i kāu kauka ke haʻi hou aku iā ʻoe e pili ana i kēia.

He aha ka ʻokoʻa ma waena o ka apoptosis a me ka necrosis?

E like me ka apoptosis, ʻo ka necrosis kekahi hana e make ai nā cell. ʻO ka ʻokoʻa nui ma waena o nā mea ʻelua, ʻo ia ka kōkua ʻana o ka apoptosis iā mākou e ulu ma mua o ko mākou hānau ʻia ʻana, i ka wā o ka embryonic (e hoʻomanaʻo i kēlā mau ʻano like me ka manamana lima?). Eia naʻe, ʻaʻole pili ka necrosis i ka ulu ʻana o ka embryonic. Hana pinepine ia ma hope o ko mākou hānau ʻia ʻana, i ka wā e hōʻino ʻia ai nā cell e nā maʻi like ʻole, nā ʻeha, nā mea ʻawahia, a pēlā aku.

Ua manaʻo nā kānaka noiʻi ma mua he ʻelua mau kaʻina hana ʻokoʻa loa ka apoptosis a me ka necrosis. Ua manaʻo lākou he make kelepona i hoʻolālā ʻia a hoʻonohonoho ʻia ka apoptosis, a ʻo ka necrosis he make kelepona i hoʻolālā ʻole ʻia a chaotic . He ʻoiaʻiʻo kēlā i kekahi ʻano. I ka necrosis, ninini ʻia nā mea o loko o kahi kelepona e make ana, pālahalaha i nā ʻiʻo a puni, a hiki ke hoʻoulu i ka mumū. He ʻano "chaotic" ia. Akā i ka apoptosis, make nā kelepona me ka ʻole o ka ninini ʻana i kā lākou mea. Akā, ua hoʻopili ʻia nā ʻāpana kelepona ma ke ʻano hoʻonohonoho, a hele mai nā kelepona i kapa ʻia ʻo phagocytes a ʻai iā lākou.

Eia nō naʻe, ua ʻike ʻia kahi noiʻi hou he mau ʻano like ma waena o kēia mau kaʻina hana ʻelua. Ua ʻike ʻia kekahi mau ʻano necrosis, e like me ka apoptosis, he necrosis i hoʻonohonoho ʻia (a i ʻole i hoʻoponopono ʻia). ʻO nā hiʻohiʻona e komo pū me ka necroptosis a me ka pyroptosis . I kekahi manawa, ke hāʻule ka apoptosis, hoʻohana ke kino i nā ʻano hana e like me ka necroptosis e hoʻopau i nā cell i makemake ʻole ʻia a i ʻole nā ​​​​​​mea ʻino. No laila, hana pū kēia mau ʻano make cell like ʻole e kōkua i ka pale ʻana i ko mākou kino.

Pehea e haʻi ʻia ai ka huaʻōlelo 'Apoptosis'?

ʻElua ala maʻamau e haʻi aku ai i ka huaʻōlelo ʻo 'Apoptosis'. ʻO kekahi ʻo 'App-up-toe-sis' a ʻo kekahi ʻo 'App-uh-toe-sis', ʻo ia hoʻi me ka ʻole o ka leo ʻelua ʻo 'p'. Hiki iā ʻoe ke nīnau i kāu kauka e pili ana i kēia, a i ʻole kekahi huaʻōlelo ʻē aʻe e pili ana i kou olakino. ʻAʻole ia he mea nui, ʻo ka mea nui ka hoʻomaopopo ʻana i ke kumumanaʻo.

ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai

He hana ʻike ʻole ʻia ka apoptosis, akā he hana koʻikoʻi loa ia e hana ʻia i loko o ko kākou kino i kēlā me kēia lā e ola ai a olakino. ʻAʻole wale kēia make ʻana o nā cell i hoʻolālā ʻia e kākoʻo i ko kākou olakino akā kōkua pū kekahi i ka pale ʻana i nā maʻi.

Inā ua ʻike ʻia ʻoe me ka apoptosis, e kamaʻilio me kāu kauka e pili ana i ia mea i hiki iā ʻoe ke hoʻomaopopo pono i ke ʻano, pehea e pili ai iā ʻoe, a me nā lāʻau lapaʻau hiki ke hana ʻia.

E hoʻomanaʻo, ʻo ka ʻike ʻana i nā mea e like me kēia e kōkua nui iā ʻoe i ka hoʻoholo ʻana i kou olakino.

ʻApoptosis , make ʻana o ke kelepona, make ʻana o ke kelepona i hoʻolālā ʻia, hana kino, olakino, maʻi, maʻi ʻaʻai