ʻO ka huaʻōlelo "cholesterol" e hoʻoweliweli iki i ka nui o kākou, ʻeā? No ka mea, ua ʻike kākou a pau inā kiʻekiʻe ka cholesterol, ʻoi aku ka kiʻekiʻe o ka loaʻa ʻana o nā maʻi koʻikoʻi e like me ka maʻi puʻuwai a me ka hahau. Akā, ʻo ka nūhou maikaʻi, hiki iā kākou ke kāohi i kēia kūlana me ka ʻai maikaʻi a me ke ʻano ola kino. A inā pono, aia nā lāʻau lapaʻau e hiki i ke kauka ke kuhikuhi. Me kēia mau mea a pau, ke noiʻi nei nā kauka a me nā ʻepekema a ke loaʻa nei nā mea hou e pili ana i ka cholesterol. No laila e nānā kākou i kā lākou i ʻike ai.
ʻAʻole like nā kānaka a pau, i kēia manawa he kūikawā ka lāʻau lapaʻau nou!
I ka wā ma mua, ua manaʻo nā kauka e like nā pae cholesterol o kēlā me kēia kanaka. Akā i kēia manawa ua loli kēlā manaʻo. I kēia manawa, ke nānā kāu kauka i kāu hōʻike cholesterol, hoʻoholo ʻo ia ʻaʻole wale ma luna o kēlā mau waiwai, akā ma luna o kāu mau kumu pilikia ʻē aʻe no ka maʻi puʻuwai.
E noʻonoʻo, ʻo kāu:
- Ke koko
- Pae kō koko
- Makahiki
- Kaumaha
Mālama pū ʻo ia i nā mea e like me kēia. I ka ʻōlelo maʻalahi, inā he nui kou pilikia o ka maʻi puʻuwai, e aʻo aku paha kāu kauka iā ʻoe e mālama i kou pae cholesterol i ka haʻahaʻa e like me ka hiki. ʻO ke ʻano kēia, ʻokoʻa paha kāu lāʻau lapaʻau mai ka lāʻau i kuhikuhi ʻia no kāu hoaaloha.
ʻO ka hoʻoikaika kino ka lāʻau lapaʻau mua ma mua o ka lāʻau lapaʻau!
E ʻōlelo kākou he kiʻekiʻe iki kou cholesterol a he kiʻekiʻe iki hoʻi ke koko, akā haʻahaʻa kou pilikia holoʻokoʻa no ka maʻi puʻuwai. I kēlā hihia, ʻaʻole e kuhikuhi koke kāu kauka iā ʻoe i ka lāʻau lapaʻau. Wahi a nā alakaʻi hou loa mai ka American Heart Association, ʻo ka laina mua o ka lāʻau lapaʻau, ʻo ia ka noho iki ʻana a me ka neʻe nui ʻana. ʻO ia hoʻi ka hoʻoikaika kino.
Hiki i ka hana kino ke hōʻemi i ka cholesterol "maikaʻi ʻole", a i ʻole LDL (Low-Density Lipoprotein) , i loko o kou koko ma 3 a 6 milligrams (mg/dL). ʻAʻole wale ia, hiki iā ia ke hoʻohaʻahaʻa i ke koko.
ʻO ke ala maikaʻi loa e hoʻoulu ai i ka hou, ʻo ia ka hana ʻana ma kahi o 150 mau minuke o ka hoʻoikaika kino kaulike i kēlā me kēia pule. Akā, mai manaʻo he paʻakikī ka loaʻa ʻana o ka manawa nui. ʻOiai he 5 a 10 mau minuke wale nō o ka hoʻoikaika kino i ka lā, hiki ke hoʻololi nui i kou pae cholesterol. No laila, e hoʻomaʻamaʻa i ka hana ʻana i kekahi mea i kēlā me kēia lā, e like me ka hele wāwae a i ʻole ke kaʻa paikikala.
ʻAʻole wale nā statins, aia kekahi mau lāʻau lapaʻau hou ʻē aʻe!
Hoʻomaʻamaʻa pinepine nā kauka i kahi papa o nā lāʻau i kapa ʻia ʻo 'Statins' ma ke ʻano he lāʻau lapaʻau no ka cholesterol. Akā, ʻaʻole hana kēia mau lāʻau no nā kānaka a pau. ʻAʻole loaʻa i kekahi poʻe nā hopena i manaʻo ʻia mai kēia mau lāʻau, a hiki i kekahi ke loaʻa nā hopena ʻaoʻao. Inā loaʻa iā ʻoe ka pilikia like, mai hopohopo. I kēia manawa, aia kekahi mau koho ʻē aʻe no kēlā.
E nānā kākou i kēia mau lāʻau lapaʻau hou ma kahi papa. Ma kēlā ʻano e maʻalahi ai ke hoʻomaopopo.
| ʻAno lapaʻau | Pehea e hana ai | Nā kiko kūikawā |
|---|---|---|
| Nā mea pale PCSK9 | ʻO kahi protein i kapa ʻia ʻo PCSK9, i hana ʻia e ke akepaʻa, ke keakea nei i ka wehe ʻana o ka cholesterol maikaʻi ʻole (LDL) mai ke kino. Ke ālai nei kēia lāʻau i kēlā protein PCSK9. | ʻO ka lāʻau pale, i hāʻawi pinepine ʻia i kēlā me kēia 2 pule, ʻoi aku ka maikaʻi ma mua o nā statins no ka poʻe me ka familial hypercholesterolemia , kahi maʻi cholesterol hoʻoilina. |
| ka lāʻau lapaʻau siRNA (e.g. inclisiran) | He ʻenehana hou kēia. He ala ia e mālama ai i nā maʻi ma ka hoʻololi ʻana i ke ʻano o ka hana a kā mākou mau genes. Hoʻohaʻahaʻa kēia lāʻau i nā pae LDL ma ka hoʻopilikia ʻana i ka gene e hana ana i ka protein PCSK9. | He lāʻau pale i hāʻawi ʻia i kēlā me kēia mau mahina. Kūpono no ka poʻe me nā kūlana e like me ka maʻi cardiovascular atherosclerotic (ASCVD) . |
| ʻAkika Bempedoic | E like me nā statins, hana pū kēia mau lāʻau lapaʻau ma ka hoʻopaʻakikī ʻana i ke kino e hana i ka cholesterol. | Lawe ʻia kēia ma ke ʻano he pila. Hiki iā ia ke hoʻemi i nā pae LDL ma kahi o 15%. I kēia manawa ua kuhikuhi ʻia i nā poʻe me ka mōʻaukala ʻohana o ka cholesterol a i ʻole nā maʻi ASCVD. |
ʻO ka mea nui loa:Pono kāu kauka e hoʻoholo inā kūpono kēia mau lāʻau lapaʻau iā ʻoe. Mai hoʻomaka a hoʻōki paha i ka lāʻau lapaʻau ma kāu iho.
ʻAi ka Nanotechnology i nā waihona momona i loko o nā kīʻaha koko
Ke piʻi aʻe ka pae kolesterol, hoʻomaka nā waihona momona (plaque) e hōʻiliʻili i loko o ko kākou mau kīʻaha koko, a i ʻole nā aʻa. Ua kapa ʻia kēia ma ke ʻano lapaʻau ʻo 'atherosclerosis.' I ka hala ʻana o ka manawa, ke ālai nei kēia mau waihona i ke kahe koko a hoʻonui i ka pilikia o ka maʻi puʻuwai a me ka hahau.
Akā, ua hana nā kānaka ʻepekema i kahi mea liʻiliʻi e hiki ke "ʻai" i kēia mau papa ʻaila. Ua kapa ʻia ʻo ia he 'nanoparticle'. ʻO ia hoʻi, he mea liʻiliʻi loa ia i ʻike ʻole ʻia e ka maka ʻōlohelohe. ʻOiai aia kēia i ke kahua hoʻokolohua, i ka wā e hiki mai ana e hoʻohana ʻia paha kahi lāʻau lapaʻau e loaʻa ana kēia 'nanoparticle' e mālama i ka 'atherosclerosis'.
Pehea ka hopena o ke olakino o ka ʻōpū i ka cholesterol
Ua lōʻihi ka manaʻo o nā kānaka noiʻi e pili ana ke olakino o ko kākou ʻōpū i nā pae cholesterol, akā ʻaʻole maopopo loa pehea i hana ʻia ai.
Akā i kēia manawa ua ʻike lākou e hiki i nā probiotics (bacteria maikaʻi) a me nā prebiotics (meaʻai no kēia mau bacteria maikaʻi) ke hōʻemi i ka cholesterol maikaʻi ʻole (LDL) a me nā triglycerides (ʻano momona ʻē aʻe i loko o ke koko). Eia kekahi, hiki i kēia mau bacteria maikaʻi i loko o ka ʻōpū ke hoʻonui i nā pae o ka cholesterol "maikaʻi", a i ʻole HDL (High-Density Lipoprotein) .
Inā makemake ʻoe e lawe i kahi probiotic a i ʻole prebiotic supplement, e kamaʻilio mua me kāu kauka. Ke noiʻi ʻia nei ka nui o ka lāʻau e pono ai e hoʻokō i nā hopena, a ʻo ka lawe nui ʻana hiki ke hoʻonāukiuki i ka ʻōpū.
Leka Lawe-Home
- He kū hoʻokahi ka kaohi ʻana i ka cholesterol i kēlā me kēia kanaka. Hoʻoholo ʻia nā hoʻoholo lapaʻau ʻaʻole wale ma muli o kou mau pae cholesterol, akā, ma muli hoʻi o nā kumu pilikia ʻē aʻe. No laila, e kamaʻilio mau me kāu kauka.
- ʻO ka hana mua a koʻikoʻi loa i kekahi lapaʻau ʻana, ʻo ia ka hoʻololi ʻana i ke ʻano o ka nohona, ʻoiai hoʻi ka hoʻoikaika kino mau .
- Inā ʻaʻole kūpono nā statins i hoʻohana pinepine ʻia iā ʻoe, mai hopohopo. Aia kekahi mau lāʻau lapaʻau ʻē aʻe i kēia manawa.
- Hiki ke manaʻo ʻia nā lāʻau lapaʻau holomua no ka mālama ʻana i ka cholesterol i ka wā e hiki mai ana.
- Mai hoʻomaka i kekahi lāʻau lapaʻau a mea hoʻopihapiha paha me ka ʻole o ke kūkākūkā ʻana me ke kauka.
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