Ua kuhikuhi anei kāu kauka iā ʻoe a i ʻole kekahi āu i ʻike ai i kahi pila i kapa ʻia ʻo Guanidine? Hiki paha iā ʻoe ke hoihoi iki, a makaʻu iki paha, ke lohe ʻoe i kēia inoa. No ka mea, ʻaʻole kēia he lāʻau lapaʻau a mākou e lohe pinepine ai. ʻO Guanidine kahi lāʻau lapaʻau i hoʻohana ʻia e mālama i kahi maʻi lapaʻau kikoʻī a kakaʻikahi. No laila, he mea nui loa ka makaʻala i kēia. No laila, i kēia lā e kamaʻilio mākou e pili ana i kēia mau pila Guanidine, nā maʻi lapaʻau a lākou e mālama ai, pehea e hoʻohana ai iā lākou, a me nā mea e makaʻala ai.
He aha ʻo Guanidine a he aha ka maʻi e mālama ai?
I ka ʻōlelo maʻalahi, he lāʻau lapaʻau ʻo Guanidine e hoʻoulu ai i nā aʻalolo a hoʻomaikaʻi i ka hana ʻiʻo. Ma ke ʻano lapaʻau, no ka papa o nā lāʻau lapaʻau i kapa ʻia ʻo 'cholinergic muscle stimulants'.
Hoʻohana nui ʻia kēia lāʻau lapaʻau e mālama i kahi maʻi autoimmune laha ʻole i kapa ʻia ʻo Lambert-Eaton Myasthenic Syndrome (LEMS) .
E hoʻomaopopo iki kākou i ke ʻano o LEMS.
E noʻonoʻo, ua hoʻokele ʻia nā neʻe ʻana o ko kākou kino e nā leka mai ka lolo. Ke hele kēia mau leka ma o nā aʻalolo a hiki i nā ʻiʻo, hiki iā kākou ke hoʻoneʻe i ko kākou mau lima a me nā wāwae a hele. Ma kahi e hui ai ke aʻalolo a me ke ʻiʻo, ua hoʻokuʻu ʻia kahi kemika i kapa ʻia ʻo 'Acetylcholine' mai nā hopena aʻalolo. Ke hiki kēia kemika i ke ʻiʻo, ʻuʻuku ke ʻiʻo, ʻo ia hoʻi, hana ia.
Akā i loko o ke kanaka me LEMS, hoʻouka hewa ka ʻōnaehana pale o ke kino i kēlā mau hopena aʻalolo. ʻO ka hopena, ʻaʻole i hoʻokuʻu ʻia ka nui o ka 'Acetylcholine' e pono ai. ʻO ka hopena, he nāwaliwali nui a me ka luhi i hoʻokumu ʻia e nā ʻiʻo i loaʻa ʻole ka leka me ka pono. He mea maʻamau ka nāwaliwali o nā ʻiʻo ma nā wāwae a me nā pūhaka.
Hana ʻo Guanidine ma ka hoʻoulu ʻana i ka hoʻokuʻu ʻia ʻana o ka ʻelele kemika (Acetylcholine) mai nā hopena aʻalolo. ʻO ke ʻano kēia e hāʻawi ia i kahi hoʻoikaika i ke kahe o nā leka i ālai ʻia a kōkua i nā ʻiʻo e hana pono hou.
Nā mea e pono ai ʻoe e haʻi i kāu kauka ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau
He lāʻau lapaʻau ʻo Guanidine e pono e hoʻohana me ke akahele. No laila, he mea nui loa e hoʻomaopopo i kāu kauka e pili ana i kāu mōʻaukala olakino piha ma mua o ke kau ʻana i kēia lāʻau lapaʻau. E hōʻoia e haʻi iā lākou inā loaʻa iā ʻoe kekahi o kēia mau kūlana:
- Maʻi puʻupaʻa: Pono ʻoe e haʻi i kāu kauka inā loaʻa iā ʻoe kekahi mau maʻi e pili ana i ka puʻupaʻa, no ka mea, he kuleana nui nā puʻupaʻa i ka hoʻopau ʻana i kēia lāʻau lapaʻau mai ke kino.
- Maʻi akepaʻa: Inā he nāwaliwali o ka hana akepaʻa, e haʻi pū aku.
- Nā pilikia o ke koko: Inā ua hōʻike ʻia he haʻahaʻa nā keʻokeʻo koko, nā keʻokeʻo koko ʻulaʻula, a i ʻole nā platelets i loko o kou koko, he ʻike koʻikoʻi loa ia.
- Maʻi Noʻonoʻo: Inā e mālama ʻia ana ʻoe no kekahi maʻi noʻonoʻo a i ʻole he mōʻaukala kou no kekahi maʻi noʻonoʻo, e ʻoluʻolu e hoʻomaopopo mai iā mākou.
- Nā Allergies: Inā he allergy kou i ka guanidine a i ʻole kekahi lāʻau lapaʻau ʻē aʻe, meaʻai, a mea hoʻoluʻu paha.
- Hāpai keiki a i ʻole ka manaʻo e hāpai: Inā hāpai ʻoe a i ʻole e hoʻolālā ana e hāpai, he mea pono e ʻōlelo ʻia kēia.
- Ka hānai waiū ʻana: E hoʻomaopopo pū i ke kauka inā he makuahine hānai waiū ʻoe.
Pehea e pono ai iaʻu ke hoʻohana i kēia lāʻau lapaʻau?
ʻO ka mea nui i ka wā e hoʻohana ai i kēia lāʻau lapaʻau, ʻo ia ke hahai pono i nā ʻōlelo a kāu kauka.
- E ale i kēia pila me ke aniani wai.
- E hoʻohana i ka lāʻau lapaʻau e like me ke kuhikuhi ʻana ma ka lepili lāʻau. Mai lawe ʻoi aku a emi mai paha ma mua o ka nui a kāu kauka e ʻōlelo ai iā ʻoe e lawe.
- Hiki ke lawe ʻia kēia ma mua a ma hope paha o ka ʻai ʻana. Eia nō naʻe, inā ʻeha kou ʻōpū, ʻo ka lawe ʻana me ka meaʻai e kōkua paha i ka hōʻemi ʻana.
- E hoʻomaʻamaʻa i ka lawe ʻana i kāu lāʻau lapaʻau i ka manawa like i kēlā me kēia lā, a i ka manawa kūpono.
- ʻO ka mea nui loa: Mai ho'ōki i ka lawe ʻana i kāu lāʻau lapaʻau no kekahi kumu me ka ʻole o ke aʻo ʻana a kāu kauka. ʻO ka hoʻōki koke ʻana hiki ke hoʻi hou mai kāu mau hōʻailona a lilo i mea ʻino.
- Inā hāʻawi ʻia i nā keiki: I ka hāʻawi ʻana i kēia lāʻau lapaʻau i nā keiki, he mea nui e kūkākūkā me ke kauka pediatric.
He aha inā lawe nui wau i ka lāʻau lapaʻau? (Overdose)
Inā manaʻo ʻoe ua lawe hewa ʻoe i ka lāʻau lapaʻau ma mua o kou manaʻo, mai hoʻokaʻulua. E kāhea koke aku i ke Kikowaena ʻIke Poisons Lahui ma ka Halemai Lahui ʻo Colombo , a i ʻole e hele i ka Emergency Treatment Unit (ETU) o ka haukapila kokoke loa.
E aʻo pū kākou e pili ana i nā hopena ʻaoʻao a me nā pilina.
E like me nā lāʻau lapaʻau āpau, hiki iā Guanidine ke hana i nā hopena ʻaoʻao. Hiki iā ia ke launa pū me nā lāʻau lapaʻau ʻē aʻe.
Nā hopena ʻaoʻao hiki ke loaʻa
Hiki i kekahi o kēia ke koʻikoʻi, a he mea maʻamau kekahi. He mea nui e makaʻala i kēia mau mea.
| ʻAno o ka hopena ʻaoʻao | Nā ʻano |
|---|---|
| Nā hopena ʻaoʻao koʻikoʻi e pono ai ke kōkua koke ʻana o ke kauka | |
| Nā hopena alerika | ʻO ka huhū o ka ʻili, ka maneʻo, ka pehu |
| Nā pilikia hanu | Paʻakikī ka hanu ʻana |
| Nā loli i ka helu o ka puʻuwai | Puʻuwai wikiwiki a ʻano ʻole paha |
| Nā hōʻailona o ka maʻi | Kuni, ʻeha puʻu |
| Nā loli noʻonoʻo | Ke ʻike ʻana a lohe ʻana paha i nā mea ʻoiaʻiʻo ʻole (Hallucinations) |
| Nā pilikia mimi | Ka paʻakikī o ka mimi ʻana a i ʻole ka loli ʻana o ka nui o ka mimi āu e hana ai |
| Ka nāwaliwali maʻamau ʻole | Manaʻo o ka luhi nui a me ka nāwaliwali i ke kino |
| Nā hopena ma ke akepaʻa | Melemele o nā maka a i ʻole ka ʻili (e like me ka jaundice) |
| Nā hopena ʻaoʻao maʻamau e pono e hōʻike ʻia i ke kauka inā hoʻomau lākou | |
| Nā ʻano laulā | Waha maloʻo, poniuniu, ʻeha poʻo, ʻeha o ka ʻōpū, nausea/luaʻi, diarrhea, nalowale o ka makemake e ʻai |
| Nā hopena ma ka ʻōnaehana nerve | ʻO ka numbness, ke kani ʻana, a i ʻole ka ʻeha ma nā lālā, nā loli o ke ʻano |
Nā lāʻau ʻē aʻe e launa pū me Guanidine (Nā Hana Lāʻau)
Hiki i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei ke hoʻopilikia i ke ʻano o ka hana ʻana o Guanidine. No laila e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei (me nā huaora a me nā huahana lāʻau lapaʻau), ʻoiai inā ʻoe e lawe ana i kekahi o kēia mau mea:
- ʻO kekahi mau lāʻau lapaʻau i lawe ʻia no ka maʻi kanesa
- Nā lāʻau lapaʻau i hāʻawi ʻia e kāohi i ka palekana ma hope o ke kāpili ʻana o ke kino
- ʻO kekahi mau lāʻau lapaʻau no ka hopu ʻana (e.g., 'Carbamazepine')
- Nā lāʻau lapaʻau no ka maʻi noʻonoʻo e like me "Clozapine"
- Nā Phenothiazines (e.g. Chlorpromazine)
- Nā lāʻau lapaʻau ʻano steroid (e.g. 'Prednisone', 'Cortisone')
- ʻO ka Sulfinpyrazone
E hoʻomanaʻo ʻaʻole i piha kēia papa inoa, no laila no kou palekana, ʻoi aku ka maikaʻi o ka haʻi ʻana i kāu kauka e pili ana i nā mea āpau āu e lawe nei.
Leka Lawe-Home
- He lāʻau lapaʻau ʻo Guanidine i hoʻohana ʻia e mālama i kahi maʻi neuromuscular kikoʻī a kakaikahi i kapa ʻia ʻo Lambert-Eaton Myasthenic Syndrome (LEMS).
- E hōʻoia e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei, ʻoiai inā he mau pilikia kou i ka puʻupaʻa, ke akepaʻa, a i ʻole ke koko.
- ʻAʻole loa ʻoe e hoʻomaka, hoʻōki, a hoʻololi paha i ka nui o ka lāʻau lapaʻau me ka ʻole o ke aʻo ʻana a kāu kauka.
- Inā loaʻa iā ʻoe kekahi mau hopena koʻikoʻi e like me ka paʻakikī o ka hanu ʻana, nā loli o ka puʻuwai, ka melemele o nā maka, a i ʻole ke kuni, e ʻimi koke i ke kōkua lapaʻau.
- Inā kānalua ʻoe ua nui ka lāʻau lapaʻau, e hele koke i ke Kikowaena ʻIke Poisons National a i ʻole ka ʻOihana Pilikia (ETU) o ka haukapila.
- E mālama i ka lāʻau lapaʻau ma kahi palekana ma ka mahana o ka lumi, mai ka hiki ʻana o nā keiki.
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