Pehea e hana ʻia ai ke koko i loko o ko kākou kino? E aʻo kākou e pili ana i ka Hematopoiesis ma ke ʻano maʻalahi

Ua noʻonoʻo paha ʻoe i kahi i puka mai ai kēia koko i loko o ko kākou kino a pehea e hana ʻia ai? Ua ʻike mākou i ke koʻikoʻi o kēia koko no ka mālama ʻana iā kākou i ke olakino, e pale iā kākou mai nā maʻi, a e lawe i ka oxygen i nā ʻāpana a pau o ko kākou kino. No laila i kēia lā e kamaʻilio mākou e pili ana i kēia kaʻina hana kupaianaha, ʻo ia hoʻi, hana ko kākou kino i nā hunaola koko hou nona iho. Ua like ia me kahi hale hana liʻiliʻi i loko o ke kino.

He aha ka hematopoiesis?

I ka ʻōlelo maʻalahi, ʻo Hematopoiesis ke kaʻina hana o ka hana ʻana i nā hunaola koko i loko o ko kākou kino. I ka make ʻana o nā hunaola koko kahiko, pono e hana mau ʻia nā hunaola koko hou e pani iā ​​lākou. Me ka ʻole o lākou, e pilikia ana kā mākou lako koko. Hoʻomaka kēia kaʻina hana ma mua o ko kākou hānau ʻana a hoʻomau i loko o kahi pōʻaiapuni i ko kākou ola.

He mea paʻakikī paha kēia huaʻōlelo, akā, he maʻalahi loa kona manaʻo. Ua hana ʻia ia me ʻelua mau huaʻōlelo Helene:

• ʻO Haîma (Haima): ʻo ia hoʻi "ke koko"
• Poiēsis: ʻo ia hoʻi "ka hana ʻana i kahi mea"

I kēia manawa ua maopopo iā ʻoe, ʻeā? Ke hui pū ʻia kēia mau huaʻōlelo ʻelua, ʻo ia hoʻi ke "hoʻokumu ʻana o ke koko." I kekahi manawa hoʻohana ʻia nā huaʻōlelo e like me `(hemopoiesis)` a me `(hematogenesis)` no kēia.

He aha nā ʻano nui o nā hunaola koko i hana ʻia e kēia kaʻina hana?

Ua hana ʻia ko kākou koko i kahi hōʻiliʻili o nā ʻano ʻano pūnaewele like ʻole. Hoʻopuka ʻia kēia mau ʻano pūnaewele a pau i ka wā o ke kaʻina hana hematopoiesis. E nānā kākou i nā ʻano nui a me kā lākou mau hana.

Aia kekahi mau ʻano o nā hunaola koko keʻokeʻo?

ʻAe, e like me kā mākou pūʻali koa, aia nā ʻano like ʻole o nā hunaola koko keʻokeʻo. Loaʻa i kēlā me kēia kahi hana kikoʻī e hana ai. ʻO nā ʻano nui:

• Nā Neutrophils
• Nā Basophil
• Nā Eosinophils
• Nā monocyte
• Nā Lymphocytes - Ua māhele hou ʻia kēia mau mea i nā pūnaewele B, nā pūnaewele T, a me nā pūnaewele pepehi kanaka kūlohelohe.

Ma hea kahi e hana maoli ai kēia hoʻokumu ʻana o ke koko?

ʻO ka hale hana nui e hana ana i kēia mau hunaola koko aia i loko o ko kākou iwi iwi . ʻO ka iwi iwi ka ʻiʻo palupalu a huʻahuʻa i loko o ko kākou mau iwi nui. Hana ʻia nā hunaola koko i loko o ka iwi iwi, a laila e hoʻohui i ko kākou mau kīʻaha koko.

Akā, ʻokoʻa iki nā wahi i hana ʻia ai kēia koko ma mua a ma hope o ko kākou hānau ʻana.

Ma mua o ka hānau ʻana (i ka wā fetal)

I nā pule mua o ka hāpai ʻana, hana ʻia ke koko i loko o kahi ʻano i kapa ʻia ʻo ka yolk sac. A laila, i ka holomua ʻana o ka hāpai ʻana, hoʻoili ʻia kēia hana i ke akepaʻa a me ka spleen. Ma kahi o ka malama ʻelima o ka hāpai ʻana, hoʻomaka ke koko e hana ʻia ma ka iwi iwi.

Ma hope o ka hānau ʻana

Mai ka lā i hānau ʻia ai kākou a hiki i ka wā makua, ʻo ka iwi iwi ke kikowaena nui no ka hana ʻana o nā hunaola koko. Eia nō naʻe, ulu pū kekahi ʻano hunaola koko keʻokeʻo i kapa ʻia ʻo lymphocytes ma nā wahi e like me ka thymus, ʻo ia kekahi ʻāpana o ka ʻōnaehana lymphatic, me ka iwi iwi.

Pehea e hana ʻia ai ke kaʻina hana o ka hematopoiesis?

Hoʻomaka kēia kaʻina holoʻokoʻa me kahi pūnaewele kūikawā hoʻokahi. Ua kapa ʻia kēia ʻo ke Kelepona Kumu Hematopoietic (HSC).E kapa kākou i kēia he "kelepona makuahine" a i ʻole he "kelepona mua." Hiki i kēia kelepona makuahine ke lilo i kele koko ʻulaʻula, kele koko keʻokeʻo, platelet, kekahi ʻano kele koko.

E noʻonoʻo i kēia me he puʻu lepo lā. E like me ka hana ʻana i nā ipu lepo, hiki ke hoʻohana ʻia kahi puʻu lepo e hana i ka ipuhao, kahi pā, a i ʻole kekahi mea ʻē aʻe, hiki ke hana ʻia kekahi ʻāpana koko mai kēia ʻāpana HSC.

ʻO kēia pūnaewele HSC e lilo mua i pūnaewele "precursor". A laila māhele a hoʻokaʻawale kēia pūnaewele precursor i kekahi mau manawa hou aku, a lilo hope i pūnaewele koko ʻulaʻula piha, pūnaewele koko keʻokeʻo, a i ʻole platelet.

• Ka hana ʻana o nā hunaola koko ʻulaʻula (Erythropoiesis): Hoʻomohala ʻia ke hunaola HSC i loko o kahi hunaola mua i kapa ʻia he "erythroblast", a lilo hope ia i hunaola koko ʻulaʻula.
• Hana ʻana o nā keena koko keʻokeʻo (Leukopoiesis): ʻElua ala hana ma ʻaneʻi. Hana ʻia kekahi mau keena koko keʻokeʻo ma o ke ala "laina cell myeloid", a me nā lymphocytes ma o ke ala "laina cell lymphoid".
• Ka hana ʻana o nā platelet (Thrombopoiesis): Hoʻomohala ʻia ke kelepona HSC i loko o kahi kelepona nui i kapa ʻia he "megakaryocyte." A laila, hoʻokumu ʻia nā platelets ma ka wāwahi ʻana i mau ʻāpana mai kēia kelepona nui.

He aha inā he pilikia me kēia kaʻina hana?

He maikaʻi loa ko kākou kino i ka hoʻomalu ʻana i ka hana ʻana o kēia mau hunaola koko. ʻO ia hoʻi, hana wale kākou i ka nui o nā hunaola e pono ai. Akā, hiki i kekahi mau maʻi ke hoʻopilikia i kēia kaʻina hana. A laila, hiki ke hana ʻia nā hunaola koko liʻiliʻi loa, a i ʻole hiki ke hana ʻia he nui loa. ʻAʻole maikaʻi kekahi o kēia mau mea no ke kino.

He aha nā kūlana e hoʻopilikia ai i ke kaʻina hana o ka hematopoiesis?

Hiki ke hoʻopilikia ʻia kēia kaʻina hana koko no nā kumu like ʻole.

• Ka ʻelemakule ʻana: I ko kākou wā ʻelemakule, hiki ke hoʻonui ʻia nā waihona momona i loko o ka iwi iwi, e hōʻemi ana i ka hiki ke hana i nā hunaola koko.
• Nā maʻi koko a me ke kanesa: ʻO nā maʻi kanesa e like me ka leukemia, lymphoma, a me ka myeloma hiki ke hana i nā nui o nā hunaola koko ʻē aʻe e hana pono ʻole.
• Kekahi mau lāʻau lapaʻau: No ka laʻana, hiki i ka chemotherapy no ka maʻi kanesa ke pepehi ʻaʻole wale i nā hunaola kanesa akā i nā hunaola koko olakino hoʻi. He hopena ʻaoʻao kēia o kekahi mau lāʻau lapaʻau.

He hana mau a koʻikoʻi ka Hematopoiesis no ko kākou ola ʻana. ʻO kēia hale hana liʻiliʻi i loko o ko kākou iwi iwi ka mea e mālama ai iā kākou i ke olakino a me ka ikaika. ʻO ia ke kumu he mea nui loa ka mālama ʻana i ke olakino o ko kākou koko.