Hopohopo mākou a pau e pili ana i ko mākou kaumaha i kekahi manawa, ʻeā? Makemake kekahi poʻe e lilo i ke kaumaha, a makemake kekahi e mālama i ke kaumaha olakino. Ua manaʻo paha ʻoe aia kekahi ʻano hana liʻiliʻi i loko o ko mākou kino e kōkua iā mākou e kāohi i ko mākou kaumaha? ʻO Leptin kekahi o ia mau mea hoʻomalu huna. I kēia lā, e kamaʻilio kākou e pili ana i ka leptin ma ke ʻano maʻalahi hiki iā ʻoe ke hoʻomaopopo.
He aha ka Leptin?
I ka ʻōlelo maʻalahi, ʻo ka leptin kahi hormone i hana ʻia e nā hunaola momona o kou kino, a i ʻole ka ʻiʻo adipose . Ua like ia me kahi ʻōnaehana hōʻailona liʻiliʻi e kōkua iā ʻoe e kāohi i kou kaumaha i ka wā lōʻihi. Pehea e hana ai i kēlā? Kāohi ʻo Leptin i kou pōloli a kōkua pū iā ʻoe e manaʻo i ka piha, a i ʻole ka māʻona .
E noʻonoʻo penei: ua like ka leptin me kahi ʻelele e haʻi i kou lolo i ka nui o ka momona i loko o kou kino. Ua ʻike wale nā kānaka ʻepekema i ka leptin i ka makahiki 1994. No laila, nui ka noiʻi e hana nei, e hoʻomaopopo pono i ke ʻano o kāna hana. Ke noiʻi ʻia nei ʻo Leptin no kona kuleana i ka hoʻokele kaumaha, ka maʻi Alzheimer , ke olakino hānau hou, a me ka hānau ʻole .
Ke lohe ʻoe e kāohi ana ka leptin i ke kaumaha, e noʻonoʻo paha ʻoe, "ʻĀ ... no laila ke manaʻo nei au e noʻonoʻo i kahi ala e kāohi ai i ka leptin." Akā, i ka ʻoiaʻiʻo, ʻaʻole maʻalahi ka hoʻoponopono ʻana i kēia hormone e like me kou manaʻo.
He aha ka mea e hana maoli me ka leptin?
ʻO ka hana nui a Leptin ke kōkua iā ʻoe e mālama i ke kaumaha o kou kino. ʻO ia hoʻi, kōkua ia i ka hana ʻana i kahi kaulike lōʻihi ma waena o ka nui o ka meaʻai āu e ʻai ai a me ka nui o ka ikehu e hoʻohana ai kou kino. Pale ʻo Leptin iā ʻoe mai ka pōloli mau ʻana. Hoʻomalu pū ia i nā hōʻailona pōloli e hele mai ana i ka wā ʻaʻole pono ke kino i ka ikehu, a i ʻole nā calories .
Hana nui ʻo Leptin ma ka hoʻopilikia ʻana i kahi ʻāpana o kou lolo i kapa ʻia ʻo hypothalamus . ʻO ka hypothalamus kahi kikowaena koʻikoʻi no ka kaohi ʻana i ka pōloli a me ka hoʻohana ʻana i ka ikehu. Eia nō naʻe, aia nā mea loaʻa leptin ma nā ʻāpana ʻē aʻe o ke kino.
ʻO ka mea nui, ʻaʻole wale ka leptin e kāohi i kou pae pōloli mai kekahi pāʻina a i kekahi. Akā, kōkua ia i ka hoʻololi ʻana i kāu mau ʻano ʻai i ka wā lōʻihi, kaohi i kāu hoʻolilo ikehu, a kōkua iā ʻoe e mālama i kou kaumaha.
Ke hoʻāʻo nei ʻoe e hoʻemi i ke kaumaha, piʻi aʻe nā pae leptin. Pehea lā e hana ai kēlā? I ka nalowale ʻana o ka momona o kou kino, emi iho nā pae leptin. Hoʻouna kēia i kahi hōʻailona i kou kino, e ʻōlelo ana, "ʻAuē, ʻaʻole au e ʻai nui ana, ua pōloli au." Hoʻoulu kēia iā ʻoe e pōloli loa a loaʻa nā makemake. Hiki i kēia ke alakaʻi iā ʻoe e ʻai nui ma mua o ka mea e pono ai. ʻO ia ke kumu e paʻakikī ai i kekahi manawa ke mālama i ka pohō kaumaha.
Ke aʻo nei nā kānaka ʻepekema i ka leptin. Manaʻo lākou e pili pū ana ia i:
- ʻO kāu metabolism
- ʻO ka ʻōnaehana endocrine, ʻo ia hoʻi, ka ʻōnaehana hormonal
- ʻŌnaehana pale kino
Pehea e kāohi ʻia ai nā pae leptin?
Hoʻopuka ʻia a hoʻokuʻu ʻia ka leptin e ka ʻiʻo adipose keʻokeʻo o kou kino, a i ʻole nā hunaola momona keʻokeʻo. ʻO kēia mau hunaola momona keʻokeʻo ke ʻano nui o ka momona i loko o ko kākou kino.
No ka mea, mai nā hunaola momona mai ka leptin, pili pono ka nui o ka leptin i loko o kou koko i ka nui o ka momona i loko o kou kino. I ka ʻōlelo maʻalahi, inā emi kou momona kino, emi kou leptin. Inā ʻoi aku kou momona kino, ʻoi aku ka nui o ka leptin.
Inā piʻi ka momona o kou kino i ka hala ʻana o ka manawa, piʻi pū ka nui o ka leptin. I ka ʻaoʻao ʻē aʻe, inā emi ka momona o kou kino, emi pū ka nui o ka leptin.
He aha ka mea e hana ai inā piʻi aʻe ka pae leptin?
Hiki i ke kanaka momona ke loaʻa i nā pae leptin kiʻekiʻe loa i loko o ko lākou kino. Ua kapa ʻia kēia he hyperleptinemia . Ke piʻi ka leptin ma kēia ʻano, hiki ke loaʻa kahi kūlana i pane ʻole ai ke kino i ka leptin. Ua kapa ʻia kēia he kūʻē leptin .
ʻO nā kūlana ʻē aʻe e pili ana me ka hyperleptinemia:
- Kaumaha
- ʻAi ʻana i ka meaʻai
- Nā maʻi neurodegenerative
- ʻO ka maʻi ʻaʻai momona ʻole ( NAFLD )
- ʻO ka maʻi Rabson-Mendenhall
He aha ke kū'ē ʻana o Leptin?
Inā loaʻa iā ʻoe ke kū'ē ʻana i ka leptin, ʻaʻole pane maʻamau kou lolo i ka leptin. ʻOiai ke hoʻomau nei ka leptin i ka hoʻouna ʻana i nā hōʻailona i kou lolo, ʻaʻole ʻoe e loaʻa i ka manaʻo "piha". ʻO ka hopena, hoʻomau ʻoe i ka ʻai ʻana, ʻoiai he nui kāu mau waihona momona i loko o kou kino.
Ma muli o kēia nele o ka leptin, manaʻo kou kino ua "pōloli" ʻoe. No ka mālama ʻana i ka ikehu, hoʻohaʻahaʻa kou lolo i kou pae ikehu a hoʻemi i ka nui o nā calorie āu e puhi ai i kou wā e hoʻomaha ana. ʻO ke ʻano kēia e emi ana kāu Basal Metabolic Rate (BMR) .
No laila, ʻo ke kū'ē ʻana o ka leptin e hoʻomake ai iā ʻoe e pōloli i nā manawa a pau, a emi pū kekahi kāu BMR. Hoʻonui kēia i ka piʻi ʻana o ke kaumaha.
Ke hoʻāʻo nei nā kānaka ʻepekema e hoʻomohala i nā lāʻau lapaʻau e hiki ke mālama i ke kū'ē leptin.
Nā hōʻailona o ke kū'ē leptin
ʻO nā hōʻailona nui o ke kū'ē ʻana i ka leptin ka pōloli mau, a i ʻole hyperphagia , a me ka hoʻonui ʻana i ka ʻai ʻana i ka meaʻai. Loaʻa kēia mau hōʻailona ke loaʻa iā ʻoe ka momona o ke kino keu, malia paha he momona keu.
Eia nō naʻe, hiki ke hoʻokumu ʻia kēia mau hōʻailona e nā kumu ʻē aʻe he nui, ʻaʻole wale ke kūʻē ʻana i ka leptin. Ke aʻo nei nā kānaka ʻepekema e pili ana i ka leptin, hiki nō paha e ʻike ʻia nā hōʻailona hou aʻe o ke kūʻē ʻana i ka leptin i ka wā e hiki mai ana.
He aha ka mea e hana ai inā loaʻa iā ʻoe ka Leptin Deficiency?
ʻO ka hemahema o ka leptin, i ʻike ʻia hoʻi he hypoleptinemia, he maʻi laha ʻole loa ia. ʻO ke ʻano nui e pili ana me kēia, ʻo ia ka hemahema o ka leptin hānau . He maʻi genetic kēia i hānau ʻia me ʻoe. ʻO ke ʻano kēia, ʻaʻole hiki i kou ʻiʻo adipose ke hana i ka leptin.
Ke nalowale ka leptin, manaʻo kou kino ʻaʻohe momona i loko o ke kino. ʻO ka hopena kēia i ka pōloli a me nā makemake nui i hiki ʻole ke kāohi ʻia. No kēia kumu, loaʻa i nā keiki ʻōpio me ka hemahema leptin hānau ka momona papa III a me ka lohi o ka wā ʻōpiopio.
Pili pū kēia ʻano me kekahi mau maʻi ʻē aʻe:
- ʻO Dyslipidemia (kahi kaulike ʻole o nā momona, e like me ka cholesterol a me nā triglycerides)
- Maʻi ake momona
- Nā maʻi bacteria pinepine
- Hyperinsulinemia (ka nui o ka hana ʻana o ka insulin)
- Hypogonadotropic hypogonadism (haʻahaʻa nā pae hormone wahine)
Pehea e nānā ai i nā pae leptin?
Hiki i kahi hoʻāʻo koko ke nānā i kāu mau pae leptin. Eia naʻe, ʻaʻole nānā pinepine nā kauka i nā pae leptin o kēlā me kēia kanaka. Manaʻo wale lākou e hana i kahi hoʻāʻo leptin i kēia mau kūlana:
- Inā loaʻa i kāu keiki liʻiliʻi ka momona papa 3
- Inā momona ʻoe a pōloli mau
He aha nā pae leptin maʻamau?
ʻO ka maʻamau, hiki i nā pae leptin ke piʻi mai:
- No nā wahine: 0.5 a 15.2 nanograms no kēlā me kēia milliliter ( 0.5 a 15.2 ng/mL )
- No nā kāne: 0.5 a 12.5 nanograms no kēlā me kēia milliliter ( 0.5 a 12.5 ng/mL )
Eia nō naʻe, hiki ke ʻokoʻa iki kēia mau waiwai maʻamau mai kēlā me kēia keʻena hoʻokolohua. No laila, e nānā pono i ka pae maʻamau ma kāu hōʻike hoʻāʻo, a i ʻole e nīnau i kāu kauka inā he mau nīnau kāu e pili ana i kāu mau hopena.
Pehea e hiki ai iaʻu ke hoʻonui i koʻu pae leptin?
ʻO kaʻoiaʻiʻo, ʻaʻohe mea nui āu e hiki ai ke hana e hoʻonui i kāu pae leptin e hōʻemi i ka pōloli a i ʻole ka makemake. ʻO ia no ka mea pili pono kāu mau pae leptin i ka nui o nā ʻiʻo adipose i loko o kou kino.
Ua ʻike ʻia kekahi noiʻi he kiʻekiʻe aʻe ka nui o ka ghrelin (ka hormone pōloli) o ka poʻe i nele i ka hiamoe a me ka haʻahaʻa o ka leptin. No laila, ʻo ka lawa ʻana o ka hiamoe hiki ke kōkua i ka mālama ʻana i kāu mau hormones i ke kaulike.
Ua hoʻopili nā kānaka ʻepekema i ka leptin a me nā triglycerides(He ʻano momona kēia i kapa ʻia he lipids). Ua hōʻike kekahi mau noiʻi i ka wā e kiʻekiʻe ai nā pae triglyceride, hoʻopilikia ia i ke ʻano o ka hana a leptin. Akā, aia nā manaʻo like ʻole e pili ana i kēia mau noiʻi. Manaʻo kekahi poʻe ʻepekema e hiki i kahi papaʻai i hoʻolālā ʻia e hoʻohaʻahaʻa i nā triglycerides ke kōkua i ka hoʻonui ʻana i nā pae leptin, akā ʻaʻole kūʻē kekahi.
He aha nā meaʻai i kiʻekiʻe i ka leptin?
He hormone ka leptin a kou kino e hana ai, ʻaʻole he meaʻai e like me ka wikamina C a i ʻole ka protein. No laila, ʻaʻohe meaʻai i loaʻa ka leptin.
No ka mea, he mea hou ka leptin, ke aʻo hou nei nā kānaka ʻepekema e pili ana i ia mea, ʻoiai pehea ia e pili ai i ka momona a me ka pohō kaumaha. Ke haʻahaʻa ka momona o kou kino, hiki ke paʻakikī ke pohō kaumaha ma muli o ke kuleana o ka leptin i ka hoʻāla ʻana i ka hōʻailona "pōloli" o ke kino.
Leka Lawe-Home
ʻAe, no laila mai kā mākou i kamaʻilio ai e pili ana i ka leptin, hiki iā ʻoe ke hoʻomanaʻo i kēia:
- ʻO Leptin kahi hormone i hana ʻia e kāu mau hunaola momona .
- ʻO ka mea nui e pili ana i kēia, ʻo ia ke kōkua iā ʻoe e kaohi i kou kaumaha i ka wā lōʻihi a hāʻawi iā ʻoe i ka manaʻo o ka "piha" .
- Ke piʻi aʻe ka momona o kou kino, piʻi aʻe ka nui o ka leptin , a i ka wā e emi ai ka momona o kou kino, e emi pū ana ka nui o ka leptin.
- ʻO ke kū'ē ʻana o ka leptin ke loaʻa ka leptin i ke kino akā ʻaʻole pane pono ka lolo iā ia. Hiki i kēia ke alakaʻi i ka piʻi ʻana o ke kaumaha.
- He mea kākaʻikahi loa ka hemahema o ka leptin.
- ʻAʻohe meaʻai i loaʻa ka leptin, no ka mea, ua hana ʻia ia i loko o ke kino.
- Hiki i ke ola olakino, ʻoiai ka hiamoe maikaʻi , ke kōkua i ke kaulike ʻana i nā hormones.
Inā ʻoe e hopohopo nei e pili ana i kou kaumaha a i ʻole makemake ʻoe i ka ʻōlelo aʻoaʻo no ka hoʻemi ʻana i ke kaumaha me ke olakino, e kamaʻilio me kāu kauka. Hiki iā ʻoe ke ʻike i kahi kauka loea i nā hormones, he endocrinologist, e kūkākūkā i nā papahana hoʻokele kaumaha. ʻO ka mea nui loa, ʻo ia ka mālama mua i kou olakino.
ʻLeptin , kaohi kaumaha, nā hormones, ka momona, ke kū'ē ʻana i ka leptin, ka pōloli, ka māʻona
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