Inā ua nānā ʻoe i kahi hōʻike hoʻāʻo koko, ua ʻike paha ʻoe i nā inoa he nui. I waena o lākou, ʻo ka mea i hopu i kou maka ʻo 'Monocytes'. Malia paha ua ʻōlelo kāu kauka i kekahi mea e pili ana i ia mea, a ua noʻonoʻo paha ʻoe i ke ʻano o ia mea. No laila, he aha kēia mau monocytes? Pehea ko lākou koʻikoʻi i ko mākou kino? I kēia lā, e kamaʻilio mākou e pili ana iā lākou ma ke ʻano maʻalahi e hiki ai iā ʻoe ke hoʻomaopopo.
He aha kēia mau monocytes?
I ka ʻōlelo maʻalahi, ʻo nā monocytes kahi ʻano o ke koko keʻokeʻo (leukocyte) i loko o ko kākou koko. E noʻonoʻo he ʻāina nui kou kino. Aia kahi pūʻali koa i hiki ke pale i kēia ʻāina mai nā ʻenemi (ʻo ia hoʻi nā germs e hoʻoulu ai i nā maʻi) e hele mai ana mai waho. ʻO kēlā pūʻali koa ko kākou ʻōnaehana pale . No laila, ua like kēia mau monocytes me kahi hui koa koʻikoʻi loa, i hoʻomaʻamaʻa kūikawā ʻia i loko o kēlā pūʻali koa.
ʻO ke kuleana nui o kēia mau koa, ʻo ia ka ʻimi a luku i nā ʻenemi e like me nā virus, bacteria, fungi, a me nā protozoa e komo i loko o ke kino. ʻAʻole wale ia, akā hana pū lākou e ʻike a hoʻopau i nā cell i loko o ko mākou kino ponoʻī i loaʻa mua i nā germs. Eia kekahi, i ka wā e paʻakikī ai ke kaua hoʻokahi, hoʻouna kēia mau koa monocyte i nā leka i nā koa ʻē aʻe o ka pūʻali koa (ʻo ia hoʻi nā cell koko keʻokeʻo ʻē aʻe) e ʻōlelo ana, "Aia kahi ʻenemi ma aneʻi, e hele mai e kōkua."
Hiki iā ʻoe ke wehewehe iki e pili ana i ke ʻano o ka hoʻokō ʻia ʻana o kā lākou mau kuleana?
Hoʻomaka kēia mau koa monocyte i ko lākou ola i loko o ko kākou iwi iwi. Ua like ia me ke kula hoʻomaʻamaʻa koa. Ma laila lākou e hoʻomaʻamaʻa maikaʻi ʻia ai a mākaukau no ke kaua. Ke oʻo maikaʻi lākou, hoʻomaka lākou e hele ma ke kino holoʻokoʻa ma o nā kīʻaha koko. Ua like ia me ka hele ʻana i ka mākaʻi.
E noʻonoʻo ua komo mai kahi huakino i loko o ko kākou kino. Ua like ia me ka ʻenemi e hoʻouka kaua ana i kahi ʻāina. A i ʻole ua puka mai ke ahi ma ke kūlanakauhale. I kēia manawa, ua hoʻokuʻu ʻia kahi hōʻailona aʻo. I ka lohe ʻana i kēia hōʻailona, hana koke nā koa monocyte kokoke. Akā i ko lākou hele ʻana i kēia kaua, hoʻololi lākou i ko lākou helehelena a māhele i ʻelua ʻano cell e hana ana i ʻelua mau hana kūikawā.
1. Nā pūnaewele Dendritic - nā ʻelele a me nā kiu
2. Nā Macrophage - Nā Koa Laina Mua
I kēia manawa, e nānā kākou i nā hana a kēlā me kēia kanaka.
Nā pūnaewele Dendritic - kikowaena kamaʻilio
Ua like kēia mau pūnaewele me ka lima kamaʻilio o kahi pūʻali koa, a i ʻole ke kikowaena kāhea o kahi keʻena kinai ahi. ʻO kā lākou hana nui, ʻo ia ka ʻike ʻana i ka ʻenemi ke hiki mai, e hoʻomaopopo i nā koa ikaika ʻē aʻe i loko o ka ʻōnaehana pale, a e noi i ke kōkua.
Loaʻa kēia mau pūnaewele dendritic ma lalo o ko mākou ʻili, ma nā papa o loko o ko mākou ihu, nā māmā, ka ʻōpū, a me nā naʻau, no ka mea, ʻo ia nā wahi e komo nui ai nā germs i ke kino.
Ke komo mai kahi germ, hele kēia mau cell a hōʻiliʻili i kahi antigen ma luna o kēlā germ. ʻO ka antigen, ma ka ʻōlelo maʻalahi, ua like ia me kahi "kāleka ʻike" no kēlā germ. ʻO ia ka mea e hiki ai i kā mākou ʻōnaehana pale ke ʻike "ʻaʻole kēia he kanaka nona i loko o ko mākou kino." Ma ka lawe ʻana i kēia kāleka ID, hoʻokuʻu nā cell dendritic i nā leka kemika kūikawā (cytokines) e haʻi aku i nā cell koko keʻokeʻo ʻē aʻe, "Eia mai kahi ʻenemi me kēia kāleka ID, e hele mai a kaua koke."
Nā Macrophages - Nā Koa Laina Mua
ʻO kēia nā commandos maoli e hele i nā laina mua a kaua. Ma hope o ka loaʻa ʻana o ka leka mai nā cell dendritic, hele pololei nā macrophages i kahi o ka ʻenemi.
ʻO ka hana a kēia mau macrophages, ʻo ia ke hoʻopuni i ka germ ʻenemi a moni holoʻokoʻa iā ia. Ma hope o ke moni ʻana, hoʻohana lākou i nā enzymes ʻawahia ikaika i loko o ko lākou kino e hoʻoheheʻe a luku i ka germ. Eia kekahi, ʻo ka "hoʻomaʻemaʻe" a me ka hoʻomaʻemaʻe ʻana i nā cell make a me nā ʻiʻo i hōʻino ʻia ma hope o ke kaua he hana koʻikoʻi ʻē aʻe ia o kēia mau cell macrophage.
Pehea ke ʻano o kēia mau monocytes?
ʻO nā monocytes ke ʻano nui loa o nā hunaola koko keʻokeʻo i loko o ko kākou koko. He pālua ko lākou nui ma mua o kahi hunaola koko ʻulaʻula maʻamau. Ke nānā ʻia ma lalo o kahi microscope, he nui lākou a maʻalahi ke ʻike.
He mea kūikawā loa ka nucleus ma waenakonu o kēia mau cell. Loaʻa iā ia nā ʻano like ʻole. I ka neʻe ʻana o ke cell ma ke kino holoʻokoʻa, hiki ke loli ke ʻano o ka nucleus. ʻO kekahi o nā ʻano nui e ʻike ʻia:
- Ke ʻano o ka pīni ʻano puʻupaʻa
- ʻAno kāmaʻa lio
- Ke ʻano o kahi pōʻai i hoʻolōʻihi iki ʻia
Ehia mau monocytes e pono iaʻu i loko o koʻu koko? (Ka pae maʻamau)
I ke kanaka makua olakino, ua manaʻo ʻia he maʻamau nā monocytes inā hana lākou ma waena o 2% a me 8% o ka helu holoʻokoʻa o nā keʻena koko keʻokeʻo. Ma ke ʻano helu, aia kēia ma waena o 200 a me 800 monocytes no kēlā me kēia microliter o ke koko.
Akā eia kekahi mea āu e hoʻomanaʻo pono ai. Hiki ke ʻokoʻa iki kēia "pae maʻamau" ma muli o ka lab kahi āu e loaʻa ai kāu hoʻāʻo koko. No laila, ke nānā ʻoe i kāu hōʻike koko, ʻaʻole wale kou waiwai, akā ʻo ka pae maʻamau no kēlā lab ua ʻōlelo ʻia ma ka ʻaoʻao like. E nānā inā aia kou waiwai i loko o kēlā pae. Inā haʻahaʻa a kiʻekiʻe paha kāu helu monocyte ma mua o ka maʻamau, e ʻike kāu kauka i ke kumu a hāʻawi iā ʻoe i ka wehewehe maikaʻi loa no ia mea.
He aha nā kūlana olakino e hiki ai ke hoʻololi i ka helu o nā monocyte?
ʻO ka maʻamau, emi a piʻi paha ka helu o nā monocytes i ka wā e hakakā ana ko mākou kino i kahi maʻi a i ʻole kahi maʻi. ʻO ke ʻano kēia, ʻaʻole paha he maʻi kēia loli o ka waiwai, akā he hōʻailona o kahi maʻi ʻē aʻe. I kekahi manawa, hiki ke loli kēia mau waiwai ma ke ʻano he hopena ʻaoʻao o kahi lāʻau lapaʻau.
Hoʻonui ʻia ka nui o nā monocytes (Monocytosis)
Ke kiʻekiʻe aʻe ka nui o nā monocytes i loko o ke koko ma mua o ka maʻamau, kapa mākou ia he monocytosis ma ke ʻano lapaʻau. Hiki i kēia ke lilo i hōʻailona o nā ʻano maʻi like ʻole. No ka laʻana, hiki ke lilo i maʻi lele e like me ka mononucleosis a i ʻole kahi maʻi autoimmune e like me ka lupus. ʻO kekahi o nā kumu nui no ka hoʻonui ʻia ʻana o nā monocytes:
- Nā maʻi autoimmune
- Nā maʻi koko
- Ka maʻi ʻaʻai
- Maʻi cardiovascular
- Ke kaumaha mau loa
- Nā maʻi pōkole a me nā maʻi lōʻihi
- Nā maʻi mumū
- Hāpai keiki
ʻO ka monocytopenia
ʻO ka helu haʻahaʻa o nā monocytes i loko o ke koko ua kapa ʻia ʻo monocytopenia . ʻO nā mea āpau e hōʻemi ana i ka helu holoʻokoʻa o nā hunaola koko keʻokeʻo hiki ke hoʻemi i nā monocytes. Aia kekahi mau kumu no kēia:
- ʻAʻai anemia aplastic
- Maʻi koko
- Nā ʻeha kuni
- ka maʻi HIV
- Kemotherapy no ka maʻi kanesa
He aha nā hoʻokolohua e nānā ai i koʻu pae monocyte?
Hoʻohana ʻia kahi hoʻāʻo koko maʻalahi loa e hoʻoholo ai i ka helu o kāu monocyte. ʻElua ʻano nui o nā hoʻāʻo i hoʻohana ʻia no kēia.
| Inoa o ka hoʻāʻo | ʻO ka mea a kēia e hōʻike nei |
|---|---|
| Helu Koko Piha (CBC) | Hāʻawi kēia i kahi wehewehe kikoʻī o kēlā me kēia ʻano cell i loko o kou koko: nā cell koko ʻulaʻula, nā cell koko keʻokeʻo, a me nā platelets. Helu ka ʻāpana 'ʻokoʻa' i nā ʻano 5 o nā cell koko keʻokeʻo (me nā monocytes) ma ke kaʻawale a hōʻike inā he maʻamau, haʻahaʻa, a kiʻekiʻe paha ko lākou mau pakeneka. |
| Helu Monocyte Loa | Hāʻawi kēia i kahi waiwai pololei o ka nui o nā pūnaewele monocyte i loko o kāu hāpana koko, ma mua o ka pakeneka. |
Ke kū mai nei nā hōʻailona ma muli o nā loli i ka helu o nā monocyte?
Eia kahi e kuhihewa ai ka poʻe he nui. ʻAʻole ʻoe e ʻike i kekahi mau hōʻailona no ka mea he haʻahaʻa a kiʻekiʻe paha kāu helu monocyte. Akā, ʻo nā hōʻailona āu e ʻike ai ua hoʻokumu ʻia e ke kūlana olakino i hoʻololi ai i kāu helu monocyte.
Eia kekahi laʻana, hiki ke piʻi aʻe kāu helu monocyte ma muli o kahi mea e like me ke kuni a i ʻole nā ʻeha kino. I kēlā hihia, e ʻike ʻoe i ke kuni a me nā ʻeha kino, ʻaʻole nā hōʻailona o ka hoʻonui ʻia o nā monocytes. No laila, ʻo ka loli ʻana o ka helu monocyte ʻaʻole ia he maʻi, akā he hōʻailona o kahi maʻi a i ʻole ke ʻano ʻē aʻe.
Pehea e hoʻihoʻi ai i ka nui o nā monocyte i ka maʻamau?
Aia nā koho lapaʻau i ke kumu o kāu mau pae monocyte. ʻO ke ʻano kēia, pono e ʻike mua ʻia a mālama ʻia ke kūlana kumu. ʻO kāu kauka ke kanaka maikaʻi loa e aʻo iā ʻoe ma kēia. Mai ho'āʻo e mālama iā ʻoe iho.
Ma keʻano laulā, eia kekahi mau mea a ke kauka e ʻōlelo ai e kāohi i nā pae monocyte:
| No ka hoʻemi ʻana i ka helu monocyte (i ka wā e kiʻekiʻe ai) | No ka hoʻonui ʻana i ka helu monocyte (i ka wā haʻahaʻa) |
|---|---|
| Ka pale ʻana i nā meaʻai e hoʻoulu ai i ka mumū i loko o ke kino (e like me nā meaʻai momona a me ke kō kiʻekiʻe). | Wahi a ke aʻo lapaʻau, ke hoʻololi nei i ka nui o nā lāʻau lapaʻau āu e lawe nei. |
| Hoʻoikaika kino mau. | Ka mālama pono ʻana i nā kūlana olakino ma lalo. |
| Ke kaupalena nei i ka inu ʻana i ka waiʻona. | Ka mālama kūpono ʻana i nā maʻi e kū nei. |
| Ka mālama kūpono ʻana i nā kūlana olakino ma lalo. | Inā nele ʻoe i ka wikamina, e lawe i nā mea hoʻopihapiha e like me ka wikamina B12, C, a me D e like me ke kauoha a kāu kauka. |
Pehea e mālama ai i ke olakino o koʻu mau hunaola monocyte?
ʻO kāu mau pūnaewele monocyte kekahi ʻāpana o kāu ʻōnaehana pale. No laila, ʻo ka mea maikaʻi loa e hana ai, ʻo ia ka mālama ʻana i kou ʻōnaehana pale holoʻokoʻa i ikaika. Eia kekahi mau mea e kōkua iā ʻoe e hana i kēlā:
- E pale iā ʻoe iho mai nā ʻeha a me nā maʻi i ka hiki: E pale i ka pili pono ʻole ʻana i nā germs.
- E ʻai i ka meaʻai kaulike a me ka hoʻoikaika kino: He mea nui ka meaʻai maikaʻi a me ka hana kino no ka ʻōnaehana pale.
- Nā hana hoʻomaʻemaʻe maikaʻi: ʻO nā hana maʻalahi e like me ka holoi pinepine ʻana i kou mau lima me ke kopa hiki ke hana i kahi ʻokoʻa nui.
- E pale i ka puhipaka: Hoʻonāwaliwali ka puhipaka i ka ʻōnaehana pale.
- E hōʻemi i ke kaumaha: He mea hōʻino ke kaumaha nui i ka ʻōnaehana pale o ke kino.
- E hiamoe pono: He mea nui ka hiamoe no ke kino e hoʻōla a hoʻoponopono i nā hunaola pale.
ʻO ka mea hope loa, ʻo nā monocytes nā kiaʻi mālie o ko mākou kino. Ke hana mau nei lākou e pale iā mākou mai nā maʻi. No laila, ʻo ka hahai ʻana i kahi nohona maikaʻi e mālama ai iā lākou i ke olakino kekahi o nā mea nui loa hiki iā mākou ke hana no ko mākou kino.
Leka Lawe-Home
- ʻO nā monocytes kahi ʻano koʻikoʻi o nā cell koko keʻokeʻo i loko o kā mākou ʻōnaehana pale e hakakā ana i nā germs.
- Inā hōʻike kāu hōʻike koko i nā monocytes kiʻekiʻe a haʻahaʻa paha, ʻaʻole paha ia he maʻi iā ia iho, akā he hōʻailona ia o kahi maʻi ʻē aʻe a i ʻole ka maʻi.
- Hiki i kahi helu koko piha (CBC) ke hoʻoholo i kāu mau pae monocyte.
- Mai makaʻu i nā waiwai i loko o kāu hōʻike ma kāu iho. E kūkākūkā mau me kāu kauka a loaʻa i ka ʻōlelo aʻoaʻo kūpono.
- ʻO ka ʻai kaulike, ka hiamoe kūpono, ka hoʻoikaika kino, a me ka hoʻēmi ʻana i ke kaumaha e hiki ai ke hoʻoikaika i kāu ʻōnaehana pale holoʻokoʻa.
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