Ke luhi mau nei ʻoe i kekahi manawa? A i ʻole e maʻi iki ʻoe, a i ʻole ʻike ʻoe i nā palapū ma kou kino holoʻokoʻa? Hiki ke loaʻa kēia ma muli o kekahi mau loli i kou koko. I kēia lā e kamaʻilio mākou e pili ana i kahi kūlana e hiki ke hana i ia mau manawa, kahi a nā kauka e kapa nei he "pancytopenia". Mai hopohopo, e kamaʻilio maʻalahi mākou e pili ana i kēia.
He aha ka pancytopenia?
I ka ʻōlelo maʻalahi, ʻo ka pancytopenia kahi kūlana kahi i haʻahaʻa ai nā ʻano nui ʻekolu o nā hunaola koko i loko o ko kākou kino - nā hunaola koko ʻulaʻula, nā hunaola koko keʻokeʻo, a me nā platelets - ma mua o ka maʻamau. E noʻonoʻo e like me kahi hale hana nui. Aia nā limahana like ʻole ma kēia hale hana no nā hana like ʻole. Pēlā nō hoʻi kēia mau hunaola koko. Loaʻa i kēlā me kēia ʻano kahi hana kikoʻī.
I kēia manawa, e nānā i ka mea e hana ʻia ke emi iho kēia mau ʻano cell:
- Nā hunaola koko ʻulaʻula i emi iho: ʻO kēia nā hunaola e lawe ana i ka oxygen ma o ko kākou kino. Loaʻa i kēia mau hunaola kahi protein kūikawā i kapa ʻia ʻo hemoglobin . ʻO ia ka mea e paʻa ai i ka oxygen. No laila, i ka wā e emi ai nā hunaola koko ʻulaʻula a i ʻole hemoglobin, kapa mākou ia he "anemia" a i ʻole "ka hemahema o ke koko."
- Ka helu o nā keʻokeʻo koko: ʻO nā keʻokeʻo koko, a i ʻole nā leukocytes, ua like ia me nā keʻena pale o ke kino. Ke kaua nei lākou i nā germs a pale iā mākou mai nā maʻi. Ma waena o kēia mau keʻokeʻo keʻokeʻo, ʻo ke ʻano nui loa i kapa ʻia he neutrophils . ʻO ka emi ʻana o nā keʻokeʻo koko i kapa ʻia he leukopenia . ʻO ka emi ʻana o nā neutrophils i kapa ʻia hoʻi he neutropenia .
- Ka helu platelet haʻahaʻa: He mau ʻāpana cell liʻiliʻi nā platelets. Akā hana lākou i kahi hana maikaʻi loa. Ke loaʻa iā mākou kahi ʻoki, kōkua kēia mau platelets i ka hoʻōki ʻana i ke kahe koko. He mea nui loa lākou no ka hoʻopili ʻana o ke koko. No laila, ke haʻahaʻa ka helu platelet, ua kapa ʻia ke ʻano he thrombocytopenia .
Inā loaʻa iā ʻoe ka pancytopenia, hiki iā ʻoe ke ʻike i nā hōʻailona i hoʻokumu ʻia e hoʻokahi, he nui, a i ʻole kēia mau kūlana āpau, ma muli o ka haʻahaʻa o kāu mau hunaola koko.
Pehea ka maʻamau o ka pancytopenia?
ʻO ka ʻoiaʻiʻo, ʻo ke kūlana i kapa ʻia ʻo pancytopenia ʻaʻole ia he mea laha ʻole e like me kou manaʻo. No ka mea he nui nā kumu hiki, he paʻakikī ke ʻōlelo pololei i ka nui o ka poʻe e loaʻa iā ia.
He aha nā hōʻailona o ka pancytopenia?
I kekahi manawa hiki i ka pancytopenia ke ʻano palupalu loa. ʻAʻole paha ʻoe e ʻike i kekahi mau hōʻailona nui. I kekahi manawa, e ʻike ke kauka iā ia ke hana lākou i ka hana koko maʻamau. Eia nō naʻe, aia kekahi mau manawa i hiki ai ke koʻikoʻi loa ke ʻano a hoʻoweliweli i ke ola. I ia mau hihia, pono ʻoe e ʻimi koke i ka lāʻau lapaʻau.
I kēia manawa, e nānā kākou i nā hōʻailona like ʻole ke emi kēia mau ʻano hunaola koko.
Nā hōʻailona o ke koko ʻulaʻula haʻahaʻa (anemia)
Inā ʻaʻole lawa kou mau hunaola koko ʻulaʻula, ʻaʻole e lawa ka oxygen i nā ʻōpū a me nā ʻiʻo ʻē aʻe o kou kino. Hiki iā ʻoe ke ʻike i nā hōʻailona e like me:
- Luhi mau i nā manawa a pau (Fatigue): He manaʻo o ka luhi a me ka makemake ʻole e hana i kekahi mea.
- Paʻakikī ka hanu ʻana (dyspnea): Manaʻo ka hanu pōkole ʻoiai me ka hoʻoikaika iki.
- Manaʻo puni.
- ʻEha poʻo.
- ʻO ka Arrhythmia kahi manaʻo e kuʻi wikiwiki ana ka puʻuwai a i ʻole ke kuʻi kūpono ʻole.
- ʻIli keʻokeʻo a i ʻole ke anu a me ka hou.
Nā hōʻailona o nā keʻokeʻo koko haʻahaʻa (leukopenia)
Ke ʻole lawa nā hunaola koko keʻokeʻo iā ʻoe, e emi ana ka hiki o kou kino ke pale aku i nā maʻi. ʻO ia hoʻi, hiki iā ʻoe ke loaʻa maʻalahi i nā maʻi. Hiki i kēia mau maʻi ke hana i nā hōʻailona e like me:
- Luhi mau ka manaʻo (Fatigue).
- Kuni a me ke anu.
- ʻEha ka ʻāʻī a i ʻole ka maʻi (pharyngitis).
- Nā ʻeha waha.
- Ke ʻū nui nei.
- Ka maʻi pākī.
- Paʻakikī ka hanu ʻana.
- Nā ʻōpū lymph pehu.
- Ke kahe nei ka pehu mai nā ʻoki.
Nā hōʻailona o ka helu platelet haʻahaʻa (thrombocytopenia)
Ke haʻahaʻa kou mau platelets, ʻaʻole e paʻa pono kou koko. Hiki i kēia ke hana i nā mea e like me:
- Ke loaʻa nei nā palapū ma kou kino mai ka mea liʻiliʻi loa.
- Ke kahe koko paʻakikī e hoʻōki a i ʻole e mau ana no ka manawa lōʻihi.
- Ka nui o ke kahe koko i ka wā o ka menstruation i nā wahine.
- Ke kahe ʻana o ke koko me ka ʻōpala, ka mimi , a i ʻole ka luaʻi.
- Nā kiko ʻulaʻula a poni paha ma ka ʻili (petechiae) - ua like me ka ʻulaʻula. I kekahi manawa e ʻike ʻia paha nā kiko ʻulaʻula, poni, a ʻeleʻele paha (purpura).
He aha ke kumu o kēia ʻano pancytopenia?
ʻO ka maʻamau, hoʻokumu ʻia ka Pancytopenia e kahi kīnā i ke kaʻina hana o ka hana ʻana i nā hunaola koko i loko o ko kākou iwi iwi . Ua ʻike anei ʻoe ua hana ʻia ko kākou mau hunaola koko i loko o ka iwi iwi? Ua kapa ʻia kēia kaʻina hana he hematopoiesis . Haʻalele kēia mau hunaola i ka iwi iwi a komo i loko o ko kākou koko ma hope o ko lākou oʻo ʻana.
No laila, hiki ke hana ʻia ka pancytopenia inā ʻaʻole lawa ka nui o nā koko koko olakino i loko o kou iwi iwi, a inā paha e luku koke ʻia kēia mau koko koko ma hope o ka hana ʻia ʻana.
Aia kekahi mau kumu e hiki ke hoʻopilikia i ka hana ʻana o kēia mau hunaola koko a luku paha iā lākou:
- Nā maʻi e pili ana i ka iwi ʻiwi:Aia kekahi mau maʻi e hoʻoulu ai i ka iwi iwi e hana i nā hunaola koko ʻē. ʻO ka hapa nui o kēia mau mea "loaʻa" i ko kākou ola ʻana. ʻO kekahi he "hoʻoilina". Eia kekahi laʻana:
- ʻAʻai anemia aplastic
- ʻO ka maʻi anemia Fanconi
- ʻO ka anemia Diamond-Blackfan
- Kanesa: Ke pālahalaha nā hunaola kanesa i ka iwi iwi, ke hoʻopilikia nei lākou i ka hana ʻana o nā hunaola koko olakino. ʻO kekahi mau ʻano kanesa e hiki ai ke hoʻoulu i ka pancytopenia:
- Leukemia
- ʻO ka maʻi ʻōpū
- ʻO ka myeloma lehulehu
- ʻO ka Myelofibrosis
- Nā maʻi Myelodysplastic
- Ka laha ʻana o ke kanesa mai kahi ʻē aʻe a i ka iwi iwi (kane metastatic)
- Nā hemahema o ka meaʻai a me ka hoʻohana ʻana i ka waiʻona: Inā ʻaʻole lawa ka nui o nā meaʻai i kou kino e like me ka huaora B12 a me ka folate , ʻaʻole paha e hiki iā ia ke hana i nā hunaola koko olakino. Eia kekahi, ʻo ka inu nui ʻana i ka waiʻona hiki ke lilo i kumu nui o ka pancytopenia.
- Nā maʻi lele: Hiki ke hana ʻia kēia ʻano maʻi e kekahi mau ʻano virus. Nā laʻana:
- ʻO ka Mononucleosis `(Mononucleosis - mono)`
- HIV (maʻi pale ʻole kanaka)
- Hepatitis C
- ʻO ka maʻi Parvovirus B19 `(Parvovirus B19)`
- ʻO ka maʻi puʻupuʻu
- Malaria
- Nā kūlana Autoimmune: ʻO kēia ka manawa e hoʻouka ai nā pūnaewele pale kino o kou kino i nā pūnaewele koko olakino. ʻO nā maʻi Autoimmune e hiki ai ke hoʻoulu i ka pancytopenia:
- Lupus
- ʻO ka ʻāʻī rheumatoid
- Nā lāʻau lapaʻau: ʻO kekahi mau lāʻau lapaʻau, ʻoiai nā lāʻau chemotherapy no ka maʻi kanesa, hiki ke hōʻemi i ka hana ʻana o nā hunaola koko.
- ʻO ka ʻike ʻia ʻana i nā mea ʻawahia: Hiki i nā mea ʻawahia o ke kaiapuni e like me ka benzene a me ka arsenic ke hōʻino i kou mau hunaola koko. Hiki i ka ʻike ʻia ʻana o ka radiation ke hōʻemi i kou mau hunaola koko.
- Ka hoʻokaʻawale ʻana o ka splenic:Hiki i kekahi mau kūlana olakino ke hoʻoulu i nā hunaola koko e hōʻiliʻili i loko o kou spleen. ʻO nā maʻi autoimmune, ka cirrhosis o ke akepaʻa, a me kekahi mau maʻi ʻaʻai ke kumu o kēia. Ke hana ʻia kēia, hiki i ka spleen ke pehu a ʻeha (splenomegaly).
I nā hihia kakaikahi, ʻaʻole hiki i nā kauka ke loaʻa ke kumu pololei o kēia emi ʻana o nā hunaola koko. Ua kapa ʻia kēia he idiopathic pancytopenia .
ʻO wai ka mea i ʻoi aku ka nui o ka pilikia o ka hoʻomohala ʻana i ka pancytopenia?
Hiki i kekahi mea me nā kūlana a mākou i kūkākūkā ai ma mua ke loaʻa i ka pancytopenia. Eia nō naʻe, inā loaʻa i kekahi o kou ʻohana kahi maʻi koko, a inā paha e loaʻa ana iā ʻoe ka chemotherapy e hoʻopilikia ai i ka hana ʻana o nā hunaola koko, ʻoi aku ka nui o kou loaʻa ʻana i kēia kūlana.
Pehea e ʻike ʻia ai ka pancytopenia?
Hiki i ka helu koko piha maʻamau (CBC) ke nānā i nā pae haʻahaʻa o nā hunaola koko. Hiki ke ʻokoʻa iki kēia mau waiwai ma muli o nā mea e like me ka makahiki, ka lāhui, a me ke kūlana olakino.
ʻO kēia nā pae i manaʻo ʻia he haʻahaʻa:
- Nā hunaola koko ʻulaʻula: No nā wāhine, emi ma lalo o 4.2 miliona mau hunaola no kēlā me kēia microliter o ke koko a i ʻole emi ma lalo o 12 grams (g) o ka hemoglobin (no kēlā me kēia deciliter). No nā kāne, emi ma lalo o 4.7 miliona mau hunaola no kēlā me kēia microliter o ke koko a i ʻole emi ma lalo o 13 grams o ka hemoglobin (no kēlā me kēia deciliter).
- Nā hunaola koko keʻokeʻo: Ma lalo o 4,000 mau hunaola koko keʻokeʻo no kēlā me kēia microliter o ke koko, a i ʻole ka helu neutrophil ma lalo o 1,800 no kēlā me kēia microliter o ke koko. ʻO nā neutrophils ke ʻano nui loa o nā hunaola koko keʻokeʻo, no laila he mea nui loa kēia helu.
- Nā Platelets: ʻAʻole i emi iho ma mua o 150,000 mau platelets i kēlā me kēia microliter o ke koko.
He aha nā hoʻokolohua ʻē aʻe e hana ʻia nei e ʻike ai i ke kumu?
Ke hoʻoholo kāu kauka he pancytopenia kou, hana paha lākou i kekahi mau hoʻokolohua hou aʻe e ʻike ai i ke kumu. Pono paha ʻoe e ʻike i ke kauka loea i nā maʻi koko (hematologist) .
Hiki i kēia mau hoʻokolohua ke komo pū me:
- ʻO ka palaki koko peripheral: Nānā kēia hoʻokolohua i kāu mau hunaola koko ma lalo o kahi microscope. Inā he mau hunaola ʻano ʻē, hiki iā ia ke hāʻawi i kahi hōʻailona e pili ana i ke kumu.
- Nā hoʻāʻo pae Vitamin B12 a me ka folate: Hoʻokumu pinepine ʻia ʻo Pancytopenia e nā hemahema meaʻai. No laila, hiki i ka nānā ʻana i kēia mau pae ke kōkua i ka hoʻoholo ʻana inā ʻo ia ke kumu.
- ʻO ka makemake ʻana i ka iwi iwi a me ka biopsy: Ma kēia kaʻina hana, lawe ke kauka i kahi laʻana liʻiliʻi o kou iwi iwi a hoʻāʻo iā ia e ʻike inā he mau maʻi e hoʻoulu ai i ka pancytopenia, e like me ke kanesa.
Ma muli o kāu mau hopena hoʻāʻo, ka mōʻaukala olakino, a me nā hōʻailona, hiki i kāu kauka ke hana i nā hoʻokolohua e like me kēia e ʻimi ai i nā kumu ʻē aʻe:
- Nā hoʻāʻo virus.
- Nā hoʻāʻo no nā maʻi.
- Nā hoʻāʻo no nā kūlana autoimmune.
- Nā hoʻāʻo no nā hoʻololi genetic (nā loli i kāu DNA).
Pehea e mālama ʻia ai ka pancytopenia?
ʻO ke kumu nui o ka mālama ʻana, ʻo ia ka ʻimi ʻana i ke kumu o ke kūlana, ka mālama ʻana iā ia, a me ka hōʻemi ʻana i nā hōʻailona. Aia kekahi mau lāʻau lapaʻau e hiki ke hoʻonui pololei i ka helu o kāu mau cell koko. ʻO kēia mau mea:
- Nā lāʻau lapaʻau: Aia kekahi mau lāʻau lapaʻau e hoʻoulu ai i ka iwi iwi a kōkua iā ia e hana i nā hunaola koko hou aku.
- Ka hoʻoili koko: Inā haʻahaʻa loa ka helu o kāu mau cell koko a hiki ke hōʻeha i kou olakino, hiki ke hāʻawi ʻia iā ʻoe kahi infusion o nā cell koko ʻulaʻula a i ʻole nā platelets.
- Ke kāpili ʻana o nā pūnaewele kumu a i ʻole ka iwi iwi: Pili kēia mau kaʻina hana i ka wehe ʻana i nā pūnaewele kumu hana ʻole (ʻo ia nā pūnaewele kumu i loko o ka iwi iwi e hana i nā pūnaewele koko) a me ke kāpili ʻana i nā pūnaewele kumu olakino.
Inā haʻahaʻa loa kāu mau pae neutrophil a nui kou pilikia o ka loaʻa ʻana o nā maʻi, hiki ke hāʻawi ʻia iā ʻoe nā antibiotics ākea .
He aha ka mea e manaʻo ai kekahi me ka pancytopenia?
ʻO kou manawa e ho'ōla ai e pili ana i ke kumu o ka haʻahaʻa o nā cell koko. ʻAʻohe ʻikepili paʻa i kēia manawa e pili ana i ka holomua o nā lāʻau lapaʻau no ka pancytopenia. Akā, nānā nā kānaka noiʻi i ka maikaʻi o nā lāʻau lapaʻau no ke kūlana kumu.
ʻO ka mea nui, ʻoiai e hoʻomaikaʻi ana nā lāʻau lapaʻau no nā kūlana kumu, e hoʻomaikaʻi pū nā hopena no ka poʻe me ka pancytopenia. No laila, he mea nui e kamaʻilio me kāu kauka e pili ana i kēia. Hiki iā ia ke haʻi iā ʻoe i ka ʻike noiʻi hou loa a wehewehe pehea e pili ai i kou kūlana.
He maʻi koʻikoʻi anei ka pancytopenia?
ʻAe, hiki ke koʻikoʻi. Aia nō hoʻi ia i ke kumu o kou helu haʻahaʻa o nā cell koko. Inā loaʻa iā ʻoe ka pancytopenia, e ʻimi kāu kauka i ke kumu a hoʻoholo i kona koʻikoʻi.
Āhea wau e hele ai i ka haukapila (ETU) i ka hikiwawe loa?
Hiki i ka Pancytopenia ke koʻikoʻi a hoʻoweliweli i ke ola inā ʻaʻole mālama ʻia. Inā ʻike ʻoe i kekahi o kēia mau hōʻailona, e hele koke i kahi lumi pilikia (ETU) :
- Inā ʻoi aku ke kuni ma mua o 101 degere Fahrenheit (38 degere Celsius).
- Inā nalowale kou ʻike (pōʻeleʻele).
- Inā pilikia nui ʻoe i ka hanu ʻana.
- Ka huikau koke.
- Inā hoʻomaka ʻoe e loaʻa i kahi ʻeha poʻo hou.
- Inā he kahe koko nui.
- Inā loaʻa iā ʻoe ka ʻeha o ka umauma.
- Inā loaʻa kahi hopu ʻana.
Hiki i ka Pancytopenia ke hoʻopilikia iā ʻoe ma nā ʻano like ʻole. Aia ia i ka haʻahaʻa o kāu mau hunaola koko a me ke kumu o ke kumu. Inā hoʻokomo kāu helu hunaola koko iā ʻoe i ka pilikia no ka anemia, ka maʻi, a i ʻole ke kahe koko nui, e hahai pono i nā ʻōlelo a kāu kauka. E nīnau pū e pili ana i nā hōʻailona e hōʻike ana e pono ʻoe e ʻike i kāu kauka.
ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai (Leka Lawe-Home)
No laila, ua maopopo paha iā ʻoe i kēia manawa ʻo ka pancytopenia kahi kūlana kahi e emi ai nā ʻāpana koko ʻekolu o kā mākou, ʻo ia hoʻi nā ʻāpana koko ʻulaʻula, nā ʻāpana koko keʻokeʻo, a me nā platelets, i ka manawa hoʻokahi. Nui nā kumu no kēia, a ʻokoʻa hoʻi nā hōʻailona.
ʻO ka mea nui loa, ʻo ia ke ʻike i ke kauka inā loaʻa iā ʻoe kēia mau hōʻailona. A laila hiki iā ia ke ʻike i ka mea i hewa a hoʻomaka i ka lāʻau lapaʻau āu e pono ai. Inā ʻike koke ʻoe, hiki iā ʻoe ke hoʻokele maikaʻi i kēia mau kūlana. No laila, e mālama i kou kino, a inā ʻike ʻoe i kekahi mea ʻē aʻe, e hoʻolohe iā ia. E noho olakino!
👩🏽⚕️ Nā nīnau hou aku (FAQs)
💬 He maʻi ʻaʻai anei ʻo Pancytopenia?
ʻAʻole! ʻAʻole he maʻi ʻo 'Pancytopenia', akā he huaʻōlelo lapaʻau. ʻO ia hoʻi, ua hoʻemi koke ʻia nā ʻano nui ʻekolu o nā cell i loko o kou koko; ʻo ia hoʻi nā cell koko ʻulaʻula (RBC), nā cell koko keʻokeʻo (WBC), a me nā platelets, i kahi pae haʻahaʻa weliweli.
💬 He aha ka mea e hana ʻia i ka mea maʻi ke hoʻemi ʻia nā ʻano hunaola koko ʻekolu i ka manawa hoʻokahi?
No ka mea, ʻaʻohe o ke kino i nā mea pale nui ʻekolu, ʻike ʻia nā hōʻailona ʻekolu i ka manawa hoʻokahi. No ka mea, emi ka 'ʻulaʻula', loaʻa ka luhi (loaʻa ka mae). No ka mea, emi ka 'keʻokeʻo', hāʻule ka pale ʻana i ka haʻahaʻa loa a ulu maʻalahi nā germs e like me ka pneumonia/fiva. No ka mea, emi nā 'platelets', ʻaʻole e pau ke kahe ʻana o ke koko mai ka ihu a me ka waha a me ka ʻeha koke o ke kino (bruising).
💬 He aha nā kumu nui o kēia maʻi?
Nui nā kumu no kēia. He maʻi viral koʻikoʻi (e like me ka dengue, HIV), kahi hopena ʻaoʻao o ka chemotherapy no ka maʻi kanesa, akā ʻo ke kumu weliweli loa he maʻi kanesa koko e hoʻopilikia ana i ka iwi iwi (Leukemia a i ʻole Lymphoma). No ka ʻike ʻana i ke kumu pololei, pono e hana i kahi 'Bone Marrow Biopsy'.
Pancytopenia , Pancytopenia, Ka hemahema o nā keena koko, Nā keena koko ʻulaʻula, Nā keena koko keʻokeʻo, Nā platelets, Iwi momona, Anemia, Leukopenia, Thrombocytopenia
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