Loaʻa iā ʻoe kēia mau hōʻailona ʻē? E kamaʻilio kākou e pili ana i ka Plasmacytoma

ʻO ka ʻeha i wehewehe ʻole ʻia ma nā wahi like ʻole o ke kino, i kekahi manawa he mau pilikia iwi i hiki ʻole ke noʻonoʻo ʻia, a i ʻole nā ​​​​​​mea ʻē aʻe i nā ʻiʻo palupalu ma nā wahi e like me ka ʻāʻī a me ke poʻo ... ʻO kēia nā mea a mākou e nānā ʻole ai i kekahi manawa. Eia nō naʻe, i nā hihia kakaikahi, he mau hōʻailona paha kēia o kahi maʻi kakaikahi i kapa ʻia ʻo Plasmacytoma. Mai hopohopo, ʻaʻole kēia he maʻi e hoʻopilikia i nā poʻe he nui. Akā he mea nui loa ka makaʻala i kēia.

He aha kēia plasmacytoma? E hoʻomaopopo maʻalahi kākou.

I ka ʻōlelo maʻalahi, ʻo Plasmacytoma kahi maʻi e like me ka Multiple Myeloma, akā ʻoi aku ka kakaikahi. Loaʻa iā mākou āpau kahi ʻano cell i loko o ko mākou kino i kapa ʻia ʻo Plasma cells . Kāhea pū kekahi poʻe i kēia mau cell B. He ʻāpana koʻikoʻi kēia o kā mākou ʻōnaehana pale. Hoʻopuka nā cell Plasma olakino i nā antibodies, a i ʻole immunoglobulins, e kōkua i ko mākou kino e hakakā i nā maʻi.

Eia nō naʻe, i kekahi manawa lilo kēia mau cell plasma olakino i mea ʻē a hoʻomaka e māhele a hoʻonui koke. A laila hōʻiliʻili kēia mau cell ʻē a hana i nā puʻupuʻu. Hiki i kēia mau puʻupuʻu ke hana i loko o ko kākou mau iwi, i loko o nā ʻiʻo palupalu o ke poʻo a me ka ʻāʻī, a i ʻole i loko o kekahi ʻōkana, e like me ka ʻōpū mimi, nā māmā, a i ʻole nā ​​puʻupaʻa.

Pehea ka hopena o Plasmacytoma i koʻu kino?

E like me kā mākou i kamaʻilio ai ma mua, hoʻomaka kēia pilikia i ka wā e lilo ai nā cell plasma olakino i mea ʻē. Hoʻonui kēia mau cell plasma ʻē a hana i kahi ʻano antibody ʻē i kapa ʻia ʻo nā protein M. Ke hoʻonui ʻia kēia mau protein M, e emi ana ka helu o nā cell plasma maoli a olakino e kōkua maoli ana i ka pale ʻana iā mākou mai ka maʻi. ʻO ia hoʻi, hiki i ko mākou pale ʻana ke hoʻonāwaliwali.

ʻElua ʻano nui o ka plasmacytoma, ma muli o nā ʻāpana o ke kino a lākou e hoʻopilikia ai:

1. Solitary Plasmacytoma of Bone (SPB): ʻO kēia ka wā e hoʻokumu ai nā cell plasma maʻamau ʻole i kahi puʻupuʻu i loko o hoʻokahi iwi i loko o kou kino. E noʻonoʻo iā ia he hoʻokahi vertebra wale nō i loko o kou iwi kuamoʻo, a i ʻole hoʻokahi wahi wale nō i loko o kou ʻūhā. Hiki i kēia SPB ke hōʻino i ka iwi a me ka ʻeha. Ma kahi o 50% o ka poʻe me SPB e loaʻa i ka myeloma multiple.

2. Extramedullary Plasmacytoma (EMP): I loko o EMP, hoʻokahi puʻupuʻu i hana ʻia me nā cell plasma ʻano ʻē e hoʻopilikia i nā ʻiʻo palupalu . ʻO ka ʻiʻo palupalu ka ʻiʻo e hoʻopuni ana, hoʻopili, a kākoʻo i ko mākou mau kino a me nā iwi. No ka laʻana, ʻo kēia hoʻi ko mākou mau ʻiʻo, nā tendon, ka ʻili, ka momona, a me ka fascia. Hiki ke loaʻa ka EMP i loko o kekahi ʻiʻo palupalu i loko o ke kino, akā ʻo ia ka mea maʻamau ma ke ala hanu o luna.ʻO ia hoʻi, ma nā wahi e like me ka lua ihu, nā sinuses, nasopharynx, a me ka larynx. Akā hiki ke hana i kekahi ʻōkana. Ma kahi o 15% o ka poʻe me EMP e loaʻa paha i ka myeloma multiple ma hope.

ʻO wai ka mea e loaʻa ana i kēia plasmacytoma? Pehea ka maʻamau?

ʻIke pinepine ʻia ka Plasmacytoma i nā kānaka ma waena o 55 a me 60 mau makahiki. Ua ʻike ʻia hoʻi he ʻoi aku ka nui o ka loaʻa ʻana o kēia maʻi i nā kāne ma mua o nā wahine.

He maʻi laha ʻole ka Plasmacytoma. Hoʻoholo wale nā ​​kauka ma kahi o 450 mau hihia hou o SPB a ma kahi o 300 mau hihia hou o EMP i kēlā me kēia makahiki. Eia nō naʻe, hiki i kekahi poʻe i hakakā me ka myeloma lehulehu no ka manawa lōʻihi ke loaʻa i ka plasmacytoma.

He aha nā hōʻailona o SPB?

ʻO ka Solitary Plasmacytoma of Bone (SPB) kahi maʻi iwi i hōʻailona ʻia e ka ʻeha iwi a i ʻole ka haki iwi . No ka laʻana, hiki iā ʻoe ke ʻeha koke i ke kua me ke kumu ʻole, a i ʻole ka ʻeha iwi ʻaoʻao. ʻO nā hōʻailona ʻē aʻe o SPB:

• ʻEha a haki paha ma nā wahi e like me kou mau iwi ʻaoʻao, thoracic vertebrae, femur, a me pelvis .
• Nā haki ʻana o ke kuamoʻo. Hiki i kēia ke hōʻino i kou kaula kuamoʻo a i ʻole nā ​​aʻa aʻalolo. Inā hana ʻia kēia, hiki iā ʻoe ke loaʻa i ka ʻeha ʻoi a hou e hele ana i lalo o kou mau wāwae a i loko o kou kua.
• I kekahi manawa, inā hoʻopilikia ka SPB i ke poʻo, hiki iā ia ke hana i ka ʻeha poʻo, ka poniuniu, a me nā pilikia ʻike .

No laila he aha nā hōʻailona o EMP?

Hōʻike ʻia nā hōʻailona o ka Extramedullary Plasmacytoma (EMP) ke kaomi ka puʻupuʻu i nā ʻiʻo palupalu, e hōʻeha ana i ka ʻeha a me ka hoʻopilikia ʻana i ka hana o ke kino.

Eia kekahi laʻana, inā he EMP kou i loko o kou ihu, manaʻo paha ʻoe ua paʻa kekahi mea i loko o kou ihu, a paʻakikī paha ke hanu ma o kou ihu. ʻOiai hiki ke loaʻa nā EMP ma nā wahi āpau o ke kino, 80% a 90% o nā hihia e loaʻa ana ma ke poʻo a me ka ʻāʻī. ʻO nā hōʻailona maʻamau o nā EMP:

• ʻEha poʻo
• Ka hoʻokuʻu ʻana o ka ihu
• Ka paʻakikī i ka moni ʻana (Dysphagia)
• ʻEha ka ʻāʻī a i ʻole ka maʻi (Pharyngitis)
• Kahe koko ihu (Epistaxis)

I ka manawa pinepine, inā pili ka EMP i kāu larynx (pahu leo), hiki iā ʻoe ke ʻike i nā hōʻailona e like me:

• leo haʻalulu
• Alanui ea i ālai ʻia
• Hanu ʻana

Mea nui:ʻO kēia mau hōʻailona plasmacytoma ua like pinepine me nā maʻi ʻē aʻe, ʻaʻole koʻikoʻi loa. No laila, mai hopohopo inā ʻike ʻoe i kahi mea e like me kēia. Eia nō naʻe, inā hoʻomau kēia mau hōʻailona no nā pule ʻelua a ʻoi aku paha ka ʻino, pono ʻoe e ʻike i ke kauka.

No ke aha i hoʻokumu ʻia ai kēia plasmacytoma? He aha ke kumu?

ʻOiaʻiʻo, ua ʻike mākou i kēia manawa ua hoʻokumu ʻia ka plasmacytoma e nā cell plasma olakino e lilo ana i mau cell ʻano ʻē a hoʻonui nui ʻia me ke kāohi ʻole. Eia naʻe, ʻaʻole maopopo i nā mea noiʻi ke kumu o kēia loli. ʻO ia hoʻi, ʻaʻohe kumu kikoʻī i loaʻa.

Pehea e ʻike ai nā kauka i ka Plasmacytoma?

Hoʻohana nā kauka i kekahi mau hoʻokolohua e ʻike ai i nā ʻano plasmacytoma a, inā loaʻa, e hoʻoholo i ke kahua o EMP.

Eia kekahi o kēlā mau hoʻokolohua:

• CT scan (Computed Tomography - CT scan): Hoʻohana kēia i nā kukuna X a me kahi kamepiula e hana i kahi kiʻi ʻekolu-dimensional (3D) o kou mau ʻiʻo palupalu a me nā iwi. Hoʻohana nā kauka i nā CT scan e nānā i ka hōʻino ʻia o ka iwi i hana ʻia e nā plasmacytomas.
• MRI scan (Magnetic Resonance Imaging - MRI): Hiki i kēia hoʻāʻo ke kiʻi i nā kiʻi kikoʻī o kou kino me ka hoʻohana ʻole ʻana i ka radiation. Hiki i ka MRI ke kōkua i ka loiloi ʻana i ka hōʻino ʻia o nā ʻiʻo palupalu i hana ʻia e EMP.
• Nā hoʻāʻo koko a me ka mimi: Hoʻohana ʻia kēia mau hoʻāʻo e ana i nā pae o kēlā mau protein M a mākou i kamaʻilio ai.
• ʻO ka endoskopi nasal: Inā kānalua ʻia kahi maʻi EMP, hiki ke hoʻohana ʻia kēia kaʻina hana e nānā i nā alahele a me nā sinuses i loko o ka ihu. Pili kēia i ka hoʻouna ʻana i kahi paipu me kahi kāmela liʻiliʻi i loko o ka ihu.
• ʻO ka biopsy nila maikaʻi: Hiki ke hoʻohana ʻia kēia ʻano hana e kiʻi i kahi hāpana o ka ʻiʻo a me ka wai mai nā ʻiʻo palupalu i hoʻopilikia ʻia e EMP.
• Biopsy: Hana ʻia kēia e lawe i kahi hāpana o ka ʻiʻo a i ʻole ka wai e nānā i nā cell plasma. ʻO kēia ke hōʻoia inā he mau cell ʻē.

He aha nā pae o EMP?

Noʻonoʻo nā kauka i nā kumu aʻe e hoʻoholo ai i ke kahua o Extramedullary Plasmacytoma (EMP):

• Pae I: Hōʻike nā hoʻokolohua he hoʻokahi wale nō puʻupuʻu ma kahi hoʻokahi ma kou kino.
• Pae II: Hōʻike nā hoʻokolohua aia nā pūnaewele EMP i loko o kāu mau lymph nodes.
• Pae III: Hōʻike nā hoʻokolohua he ʻoi aku ma mua o hoʻokahi puʻupuʻu EMP.

He aha nā lāʻau lapaʻau no ka Plasmacytoma?

ʻO ka mea maikaʻi loa, aia nā lāʻau lapaʻau no kēia ʻano. Hoʻōla nā kauka i ka plasmacytoma iwi hoʻokahi (SPB) me ka radiation therapy.I kekahi manawa, inā loaʻa i kekahi kēlā mau protein maʻamau ʻole (nā protein M) i loko o ko lākou koko a mimi paha a he plasmacytoma nō hoʻi, e hoʻohana pū nā kauka i nā lāʻau lapaʻau no ka myeloma maha.

Hiki ke mālama ʻia ka plasmacytoma extraosseous (EMP) me ke ʻoki kino a/a i ʻole chemotherapy a i ʻole immunotherapy . Na kāu kauka e hoʻoholo i ka lāʻau kūpono loa e pili ana i kou kūlana.

Hiki ke pale ʻia ka ulu ʻana o ka plasmacytoma?

ʻO kaʻoiaʻiʻo, e like me ka myeloma maha, ʻaʻohe ala i ʻike ʻia e pale aku ai i ka ulu ʻana o ka plasmacytoma. No ka mea, ʻaʻole ʻike ʻia ke kumu pololei, he paʻakikī ke ʻōlelo pehea e pale aku ai.

ʻEhia ka lōʻihi e hiki ai iā ʻoe ke ola me Plasmacytoma?

He pilikia kēia no nā kānaka he nui. Ma kahi o 60% o ka poʻe me SPB e ola mau ana i ʻelima mau makahiki ma hope o ka hōʻoia ʻana. Ma kahi o 82% o ka poʻe me EMP e ola mau ana i ʻelima mau makahiki ma hope o ka hōʻoia ʻana. He mau helu wale nō kēia, hiki ke ʻokoʻa kēia mai kēlā kanaka a kēia kanaka.

ʻO ka mea pōʻino, hiki i ka plasmacytoma ke hoʻi hou mai i kekahi manawa, a i ʻole e ulu aʻe ma kahi ʻē aʻe o ke kino. Eia kekahi, hiki i kekahi poʻe i loaʻa iā SPB a i ʻole EMP ke loaʻa i ka myeloma multiple ma hope. Hiki i kēia ke hoʻopilikia i ka lōʻihi o ko lākou ola ʻana.

Pehea wau e mālama ai iaʻu iho? He aha kaʻu e hana ai?

Ma muli o ke ʻano i kapa ʻia ʻo plasmacytoma hiki ke ulu a lilo i myeloma lehulehu, inā loaʻa iā ʻoe ka plasmacytoma, pono ʻoe i ka mālama hahai ʻana no ke ola holoʻokoʻa ma hope o ka pau ʻana o ka mālama ʻana. He mea nui loa kēia.

ʻO ka maʻamau, ʻo kēia mālama hahai ʻana e komo pū me nā hoʻāʻo koko maʻamau a me nā hoʻāʻo kiʻi (e like me CT a me MRI). E nānā kēia mau kauka iā ʻoe no nā hōʻailona o ka myeloma maha. Inā loaʻa iā ʻoe ka plasmacytoma, e nīnau i kāu kauka i ke ʻano o ka mālama hahai āu e manaʻo ai.

He maʻi koko laha ʻole ka Plasmacytoma e like me ka myeloma maha. ʻO ka mea pōmaikaʻi, hiki i nā kauka ke mālama pono i ka hapa nui o nā hihia o ka plasmacytoma, e hoʻemi ana i ka puʻupuʻu a hoʻomaha i nā hōʻailona. Eia nō naʻe, ʻo ka ʻike ʻia ʻana me ka plasmacytoma ʻo ia hoʻi e pono ʻoe e noho me ka nānā ʻana i ke kauka no ke koena o kou ola. ʻAʻole maʻalahi ke ola me kahi maʻi e nalowale loa. Inā ʻoe e noho nei me ka plasmacytoma, e nīnau i kāu kauka e pili ana i nā ala e kōkua ai iā ʻoe e hoʻomanawanui i kēia maʻi mau. E hauʻoli lākou e kōkua iā ʻoe.

ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai (Leka Lawe-Home)

ʻAe, e hōʻuluʻulu kākou i kekahi o nā mea e pono ai ʻoe e hoʻomanaʻo mai nā mea a mākou i kamaʻilio ai:

• He maʻi laha ʻole ka Plasmacytoma i hoʻokumu ʻia e nā ʻōpū e ulu maʻamau ʻole mai nā pūnaewele plasma .
• ʻElua ʻano nui o kēia: SPB, ka mea e hoʻopilikia ai i nā iwi , a me EMP, ka mea e hoʻopilikia ai i nā ʻiʻo palupalu .
• Hiki i nā hōʻailona ke komo pū me ka ʻeha o ka iwi, ka haki ʻana o ka iwi, ke poʻo ʻeha, ka ihu wai, a me ka paʻakikī i ka moni ʻana . Inā hoʻomau a ʻoi aʻe paha kēia mau hōʻailona, ​​e ʻimi i ke kōkua lapaʻau.
• ʻAʻole i loaʻa kahi kumu kūpono no kēia , no laila ʻaʻohe ala e pale aku ai.
• Aia nā ʻano lapaʻau e like me ke ʻoki kino, ka radiation therapy, ka chemotherapy, a me ka immunotherapy .
• He mea nui loa ka hahai ʻana i ke ola holoʻokoʻa ma hope o ka mālama ʻana, no ka mea, hiki i kēia ke ulu a lilo i myeloma maha a hoʻi hou mai paha.
• Hiki ke paʻakikī ke noho me kēia maʻi. E kamaʻilio me kāu kauka a loaʻa ke kākoʻo āu e pono ai.

Manaʻolana wau he mea pono kēia ʻike iā ʻoe. E ola kino!

plasmacytoma , maʻi ʻaʻai, maʻi koko, maʻi ʻaʻai iwi, maʻi ʻaʻai palupalu, myeloma lehulehu