Ua lohe anei ʻoe i kēia maʻi kanesa ʻē? E aʻo kākou e pili ana i ka Signet Ring Cell Carcinoma

Ua lohe paha ʻoe i kekahi ʻano maʻi kanesa i kapa ʻia ʻo "Signet Ring Cell Carcinoma"? Malia paha he ʻano ʻē iki kēia inoa. Akā, he ʻano maʻi kanesa kēia e pono ai kākou a pau e makaʻala. No ka mea, he ʻano maʻi kanesa ia e pālahalaha wikiwiki iki ana, ʻo ia hoʻi, he ʻano huhū . No laila, e hoʻomaopopo pono kākou i kēia i kēia lā, me he mea lā e kamaʻilio ana kākou me kahi hoaaloha.

He aha ka Signet Ring Cell Carcinoma?

I ka ʻōlelo maʻalahi, ʻo Signet Ring Cell Carcinoma (SRCC) kahi ʻano maʻi kanesa. Hoʻomaka pinepine ia ma kou ʻōpū gastrointestinal , ʻoiai kou ʻōpū. Loaʻa iā ia kona inoa ʻē ma muli o ke ʻano o kēia mau hunaola kanesa ma lalo o kahi microscope. Ua like lākou me ke apo, akā me kekahi ʻaoʻao i hoʻolōʻihi iki ʻia, e like me ka "apo signet" i hoʻohana ʻia e sila i nā leka i ka wā kahiko.

ʻO kēia maʻi kanesa, i kapa ʻia ʻo "SRCC", no loko o ke ʻano o ke kanesa i kapa ʻia ʻo "Adenocarcinoma." ʻO ke ʻano kēia, ua kū mai kēia kanesa mai nā pūnaewele i loaʻa i loko o nā glands o ko mākou kino, a mākou e kapa nei he mau pūnaewele glandular . He ʻano pūnaewele maʻamau kēia i loaʻa i loko o nā ʻiʻo i loko o ko mākou mau ʻōpū.

Eia nō naʻe, hiki ke paʻakikī iki ka ʻike ʻia ʻana me ka SRCC. He maʻi kanesa wikiwiki loa kēia, no laila pono e hoʻomaka koke ka mālama ʻana. Eia nō naʻe, ke hana nei nā mea noiʻi e ʻimi i ka lāʻau lapaʻau maikaʻi loa no kēia ʻano. Inā loaʻa iā ʻoe kēia ʻano, pono ʻoe e hana pū me kāu kauka oncologist e hoʻoholo i ka hoʻolālā lapaʻau maikaʻi loa.

Aia kekahi mau ʻano like ʻole o kēia maʻi kanesa?

ʻAe, hoʻokaʻawale nā ​​kauka i kēia (SRCC) e like me ke kino e hoʻomaka mua ai ke kanesa. ʻO ka hapa nui o ka manawa, ʻo ia hoʻi, ma kahi o 90 pakeneka o (SRCC) e kū mai ana ma ke ʻano he kanesa ʻōpū . He mea kākaʻikahi loa, hoʻomaka ia ma nā wahi ʻē aʻe o ke kino kahi i loaʻa ai nā hunaola glandular.

Eia kekahi laʻana, ʻike ʻia he 1% a emi mai paha o nā maʻi kanesa ma nā ʻōpū ma lalo nei he (SRCC)'':

• Ka maʻi ʻaʻai kolona
• Ka maʻi ʻaʻai rectum
• Ka maʻi ʻaʻai pancreatic
• Ka maʻi ʻōpū
• Ka maʻi ʻaʻai ʻōpū
• Ka maʻi ʻaʻai ʻōpū
• Ka maʻi ʻaʻai ʻāpiki
• Ka maʻi ʻaʻai prostate
• Ka maʻi ʻaʻai umauma

Pehea ka maʻamau o kēia maʻi kanesa i kapa ʻia ʻo (SRCC)''?

I kēia manawa, e nānā, 90-95 pakeneka o nā maʻi ʻaʻai ʻōpū he ʻano "Adenocarcinomas". No kēlā mau ʻano maʻi ʻaʻai ʻōpū "Adenocarcinomas" , ma waena o 35% a me 40% he "SRCC" .

ʻO ke kanesa ʻōpū ka ʻelima o nā maʻi kanesa maʻamau ma ka honua. Eia nō naʻe, ua emi ka nui o nā maʻi kanesa ʻōpū i hoʻohālikelike ʻia me ka wā ma mua. ʻO kēia ma muli o ka loaʻa ʻana o nā lāʻau lapaʻau hou e hiki ke pale aku i nā mea e like me ka maʻi me ka bacteria Helicobacter pylori (H. pylori), he mea pilikia ia no ka maʻi kanesa ʻōpū.

Akā, ʻo ka mea kupanaha, ke piʻi nei ka nui o nā maʻi ʻōpū i ʻike ʻia he (SRCC). ʻAʻole maopopo i nā kānaka ʻepekema ke kumu.

He aha nā hōʻailona o kēia maʻi kanesa? He paʻakikī anei ke ʻike mua?

Eia kekahi mea e makaʻala ai. ʻIke pinepine ʻia nā hōʻailona o ka SRCC ma hope o ka laha ʻana o ke kanesa . No laila, ʻaʻole ʻike ka poʻe he nui he pilikia ko lākou i nā pae mua. ʻO ka SRCC e hoʻomaka ana ma ka ʻōpū e laha pinepine i ka peritoneum, nā iwi, a i nā wahine, nā ovaries.

ʻO nā hōʻailona o ka (SRCC) e komo pū paha me:

• ʻŌhū, ʻai ʻole
• ʻEha ʻōpū
• Ka luaʻi a me ka luaʻi
• Ka maʻi pākī
• Nā ʻōpala koko
• Luhi pinepine
• ʻEha hui
• ʻEleʻele, ka wikiwiki o ka puʻuwai, a me ka paʻakikī o ka hanu ʻana

E noʻonoʻo, loaʻa i kāu hoaaloha ka ʻeha mau o ka ʻōpū a me ka ʻōpū ʻeha ma hope o ka ʻai ʻana. Manaʻo paha ʻo ia, "ʻAuē, he gastritis maʻamau kēia." Akā hiki ke ʻike ʻia ka nui o kēia mau hōʻailona i nā maʻi ʻōpū ʻoi aku ka koʻikoʻi ma mua o ke kanesa. No laila, mai makaʻu e manaʻo he kanesa ia no ka mea he mau hōʻailona kou. Eia nō naʻe, inā he mau hōʻailona mau a hiki ʻole ke mālama ʻia, he mea naʻauao mau ke ʻike i ke kauka.

No ke aha e ulu ai kēia ʻano maʻi kanesa? He aha ke kumu?

Hoʻomaka ka SRCC i ka wā e hoʻomaka ai nā pūnaewele glandular ʻano ʻē e hana i nā kope o lākou iho. Hiki i kēia mau pūnaewele ʻano ʻē ke hana i nā puʻupuʻu, pālahalaha, a luku i nā ʻiʻo olakino. Eia nō naʻe, ʻaʻole maopopo i nā mea noiʻi ke kumu e lilo ai nā pūnaewele i pili i ka SRCC i mea ʻano ʻē ma kahi mua.

Ua hōʻike kekahi mau noiʻi e pili ana paha nā loli i loko o kahi gene i kapa ʻia ʻo CDH1, ka mea e hana ai i kahi protein koʻikoʻi i loko o nā pūnaewele glandular. Eia nō naʻe, nui nā mea e pono e ʻike ʻia e pili ana i ke ʻano o ka lilo ʻana o nā pūnaewele glandular (SRCC) i mea ʻino.

Pehea e ʻike ai nā kauka i kēia maʻi ʻaʻai (SRCC)?

Hoʻomaka pinepine ka ʻike ʻana o (SRCC) me ke kauka e nīnau ana e pili ana i kāu mau hōʻailona a hana i kahi hoʻokolokolo kino. Hiki i kēia ke kōkua iā lākou e loaʻa kahi manaʻo o kahi o ka pilikia i loko o kou kino. A laila hiki iā lākou ke hoʻoholo i nā hoʻokolohua e hana ai. Hiki i kēia mau hoʻokolohua ke komo pū me:

• Nā hoʻāʻo kiʻi:Hoʻohana pinepine ʻia ka scan computed tomography (CT) no ka ʻike ʻana i nā puʻupuʻu i loko o ke ala ʻōpū. Inā ʻike kāu kauka i kahi puʻupuʻu kānalua, hiki iā lākou ke kauoha i kahi scan PET e ʻike inā ua pālahalaha nā hunaola kanesa.
• Nā hoʻāʻo koko: E lawe ʻia kahi hāpana o kou koko a e hana ʻia kekahi mau hoʻāʻo. Hiki i kēia ke komo pū me nā hoʻāʻo e nānā i kou olakino laulā, a me nā hoʻāʻo e nānā i nā hōʻailona o nā maʻi e like me ke kanesa.
• Biopsy: ʻO kēia ka hoʻāʻo koʻikoʻi loa . Pono ke kauka e lawe i kahi laʻana o ka puʻupuʻu holoʻokoʻa a i ʻole ka ʻiʻo a nānā iā ia. Penei e hōʻoia ai ke kauka inā he SRCC ia. E nānā kahi pathologist i ka laʻana ma lalo o kahi microscope e ʻike inā he mau cell "signet ring". Hiki iā lākou ke hana i kahi hoʻāʻo kūikawā i kapa ʻia ʻo immunohistochemistry ma ka laʻana e hōʻoia inā he maʻi kanesa nā cell.

Pehea e hiki ai ke mālama ʻia kēia? Hiki ke ho'ōla ʻia?

ʻO ka lāʻau lapaʻau āu e loaʻa ai ma muli o nā kumu he nui. ʻO nā mea nui kahi i hoʻomaka ai ke kanesa (ʻano) a me ka mamao o kona laha ʻana (kahua). Hoʻoholo ʻia kēia mau mea a pau ma hope o ke kamaʻilio ʻana me kāu kauka. He nui ka poʻe me (SRCC) e pono ai ma mua o hoʻokahi lāʻau lapaʻau, a i ʻole ka hui pū ʻana o nā lāʻau lapaʻau . Hiki i kēia mau mea ke komo pū me:

• ʻO ke ʻoki endoscopic: Inā ʻaʻole i pālahalaha ke kanesa, hiki ke hana ʻia ke ʻoki ʻana me ka hoʻohana ʻana i kahi ʻano hana i kapa ʻia he esophagogastroduodenoscopy. Pili kēia i ka wehe ʻana i ka puʻupuʻu ma o kahi ʻōmole i hoʻokomo ʻia ma ka waha. He hana ʻaʻole invasive kēia.
• ʻO ka ʻoki ʻana i ke kino: ʻO kēia ke kaʻina hana ʻoki maʻamau no SRCC. ʻO kēia no ka mea ua holomua pinepine ke kanesa i ka wā e ʻike ʻia ai. Pili kēia i ka wehe ʻana i ka puʻupuʻu holoʻokoʻa a me nā ʻiʻo a puni. ʻOiai ʻo ka SRCC e laha pinepine ana i nā lymph nodes, wehe pū nā kauka i kekahi o nā lymph nodes.
• ʻO Hyperthermic Intraperitoneal Chemotherapy (HIPEC): He hui pū ʻana kēia o ke ʻoki kino a me ka chemotherapy e mālama i ka maʻi kanesa i pālahalaha i loko o ka lua ʻōpū. Ma hope o ka wehe ʻana o ke kauka i ka puʻupuʻu, hoʻokomo pololei ʻia nā lāʻau chemotherapy i loko o ka lua ʻōpū. A laila hoʻomehana ʻia nā lāʻau. ʻOi aku ka ʻawahia o nā lāʻau chemotherapy i nā hunaola kanesa i koe.
• ʻO ka chemotherapy ʻōnaehana: Hiki i kāu kauka ke ʻōlelo aku i kēia koho. Maanei, hāʻawi ʻia ʻoe i nā lāʻau chemotherapy, ma ke ʻano he pila a i ʻole he IV. Hele kēia mau lāʻau i loko o kou kino a pepehi i nā hunaola kanesa. ʻOiai he lāʻau maʻamau ka chemotherapy no (SRCC), ʻaʻole paha ia e maikaʻi loa i ka wā lōʻihi.
• Hoʻōla radiation:Paipai kekahi mau kauka i ka radiation therapy a me ka chemotherapy e pepehi i nā hunaola kanesa i koe ma hope o ke ʻoki ʻana. Hoʻohana ka radiation therapy no (SRCC) i kahi mīkini ma waho o ke kino e kuhikuhi i ka ikehu i nā hunaola kanesa.
• Nā hoʻokolohua lapaʻau: Ua hoʻolālā ʻia kēia mau mea e hoʻāʻo i ka palekana a me ka pono o nā lāʻau lapaʻau hou no ka maʻi kanesa. Ke hoʻomau nei nā kānaka ʻepekema i ke aʻo ʻana i nā loli o nā cell e alakaʻi ai i (SRCC), me ka pahuhopu o ka hoʻomohala ʻana i nā lāʻau lapaʻau e hiki ke hoʻōki i kēia mau loli. ʻO ke komo ʻana i kahi hoʻokolohua lapaʻau e hāʻawi paha iā ʻoe i kahi manawa e loaʻa ai kēia mau lāʻau lapaʻau hou.

Inā loaʻa iaʻu ka (SRCC), he aha nā ʻano mea e pono iaʻu e kū i mua?

ʻO kaʻoiaʻiʻo, ʻaʻohe mea hiki ke wānana pololei i ke ʻano o ka ʻike o kekahi me SRCC. Akā ʻo ka mea a mākou e ʻike ai, i ka hoʻohālikelike ʻia me nā ʻano carcinoma ʻē aʻe, he maʻi kanesa wikiwiki loa ka SRCC . ʻOi aku ka nui o ka hiki ke hoʻi hou ma hope o ke ʻoki ʻana. He mea paʻakikī hoʻi ke kāohi i ka wā lōʻihi me nā lāʻau lapaʻau maʻamau e like me ka chemotherapy.

E hilinaʻi nui kou ʻike i kāu mau pahuhopu. Inā he pae mua ka maʻi ʻaʻai, ʻo ka pahuhopu paha ka hoʻōla piha ʻana i ke kanesa a mālama iā ia i ka "hoʻōla ʻana." Inā ua pālahalaha ke kanesa, e like me ka "Pae 4," hiki i ka lāʻau lapaʻau ke kōkua iā ʻoe e ola ʻoluʻolu.

E nīnau i kāu kauka i ka mea e manaʻo ai ma muli o kāu hōʻailona.

Pehea e hiki ai iaʻu ke mālama iaʻu iho? He aha kaʻu e hiki ai ke hana?

He mea nui e aʻo i ka nui o kāu hiki e pili ana i kāu hōʻailona (SRCC). ʻOi aku ka maikaʻi o ka loaʻa ʻana o nā pane i nā nīnau (ʻoiai inā he paʻakikī) ma mua o ka hopohopo e pili ana i ka mea e hana nei i kou kino. E nīnau i kāu kauka pehea e hoʻopilikia ai kāu hōʻailona i kou olakino holoʻokoʻa a me ke ola o kēlā me kēia lā.

Eia kekahi, e nīnau i kāu kauka inā hiki iā ʻoe ke pōmaikaʻi mai nā lawelawe mālama palliative. ʻO ka pahuhopu o ka mālama palliative ka hāʻawi ʻana i ka hōʻoluʻolu mai nā hōʻailona. ʻOiai ke ʻano o kou maʻi kanesa, hiki i kēia mau lawelawe ke kōkua i ka hōʻoluʻolu ʻana i nā hōʻailona o ke kanesa a me nā hopena ʻaoʻao o ka lāʻau lapaʻau.

Āhea wau e ʻike ai i ke kauka?

Inā loaʻa iā ʻoe nā hōʻailona ʻōpū mau a wehewehe ʻole ʻia - no ka laʻana, ʻeha ʻōpū a i ʻole ka maʻi pākī - e ʻike i ke kauka. I ka manawa pinepine, hiki i kēia ke lilo i mau hōʻailona o kahi maʻi ʻoi aku ka koʻikoʻi. I ka manawa kākaʻikahi loa , hiki iā lākou ke lilo i mau hōʻailona o kahi puʻupuʻu i loko o ka lua ʻōpū.

Āhea wau e hele ai i ka Emergency Treatment Unit (ETU) ?

Inā loaʻa iā ʻoe nā hōʻailona e like me ka dizziness, ke kuni, a me ka paʻakikī o ka hanu ʻana (dyspnea), e hele koke i kahi lumi pilikia. He mea maʻamau kēia mau hōʻailona me nā kūlana he nui e pono ai ka mālama ʻana i ka pilikia, me ka koʻikoʻi (SRCC).

He aha nā nīnau e pono iaʻu e nīnau aku i kaʻu kauka?

He mea nui e hoʻomaopopo i nā mea āpau e pili ana i kāu hōʻailona, ​​​​me ke ʻano o kona hopena i kou ola o kēlā me kēia lā. Hiki iā ʻoe ke nīnau i nā nīnau e like me:

• He aha ke ʻano o ka maʻi kanesa i loaʻa iaʻu?
• I ke kahua hea koʻu maʻi ʻaʻai?
• He aha ka lāʻau lapaʻau āu e paipai nei?
• He aha nā hopena ʻaoʻao e hiki iaʻu ke manaʻo mai ka lāʻau lapaʻau?
• He aha kaʻu wānana (nā hopena me ka mālama ʻana)?
• He aha nā hana e hiki iaʻu ke hana e maʻalahi ai ka noho ʻana me (SRCC)?

ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai

ʻO ka ʻike ʻana he signet ring cell carcinoma (SRCC) kou maʻi kanesa he mea nui ia no nā kauka e ʻōlelo ana i ka lāʻau lapaʻau e pili ana i ke ʻano o ke kanesa. Akā ʻo ka nīnau nui loa no nā poʻe he nui: "Pehea lā e pili ai kēia i koʻu olakino?" ʻAʻole maʻalahi ka pane. ʻO ka loaʻa ʻana o (SRCC) ʻo ia hoʻi, pono paha ʻoe e hana i kekahi mau hoʻoholo paʻakikī e pili ana i kāu mau koho lapaʻau. Pono paha ʻoe i ke kōkua e hoʻomaopopo pehea e hoʻololi ai kāu hōʻailona i kou ola o kēlā me kēia lā.

Mai makaʻu, e kamaʻilio me kāu kauka a noi i ke kōkua. ʻO ia ke kanaka maikaʻi loa e wehewehe i nā ʻanuʻu hiki iā ʻoe ke hana e hoʻokele i nā mea e hiki mai ana. E hoʻomanaʻo, ʻaʻole ʻoe hoʻokahi.

ʻO ke Kanesa Kelepona Signet Ring, SRCC, Kanesa ʻŌpū, Nā Hōʻailona Kanesa, Lāʻau Kanesa, Adenocarcinoma, Kanesa ʻŌpū