Hiki paha iā ʻoe kēia pilikia 'lēleo' i loko o kou koko? E aʻo kākou e pili ana i ka Smoldering Multiple Myeloma (SMM)!

I kekahi manawa, hiki ke kū mai nā pilikia nui i loko o ko kākou kino me ka ʻole o nā hōʻailona o waho. Manaʻo paha ʻoe, "Auē, pehea lā e hiki ai kēlā?" ʻAe, hiki nō. I kēia lā, e kamaʻilio mākou e pili ana i kahi kūlana kikoʻī e hiki ke ulu mālie, me ka ʻole o ka hōʻike ʻana i nā hōʻailona, ​​akā hiki ke lilo i maʻi kanesa koʻikoʻi i ka wā e hiki mai ana. Ua kapa ʻia kēia e nā kauka he (Smoldering Multiple Myeloma - SMM) . I ka ʻōlelo maʻalahi, ua like kēia me kahi pae mua o kahi maʻi i kapa ʻia ʻo "chronic multiple myeloma."

He aha ka Smoldering Multiple Myeloma (SMM)?

I ka ʻōlelo maʻalahi, ʻo Smoldering Multiple Myeloma kahi maʻi e hoʻopilikia ai i kou koko a me ka iwi iwi. Hiki i kēia ke ulu i loko o kahi maʻi koko laha ʻole i kapa ʻia ʻo Multiple Myeloma (MM) ikaika . I kēia manawa ke noʻonoʻo nei paha ʻoe, "He aha kēia myeloma maha?" ʻO nā cell plasma kahi ʻano cell koko keʻokeʻo i loko o kā mākou ʻōnaehana pale. ʻO kēia nā mea e hana i nā antibodies e kōkua i ko mākou kino e hakakā i nā maʻi. Eia nō naʻe, i kekahi manawa hiki i kēia mau cell plasma ke loli a lilo i mau cell ʻē. ʻO ia ka manawa e kū mai ai kahi maʻi i kapa ʻia ʻo multiple myeloma.

No laila, ʻo SMM ke kahua "mālie" ma mua o kona lilo ʻana i maʻi kanesa i kapa ʻia ʻo multiple myeloma, me ka ʻole o nā hōʻailona. I kekahi manawa hiki ke hala nā makahiki no ka SMM e lilo i multiple myeloma ikaika. ʻO ka mea kupanaha, ʻaʻole loa e ulu kekahi poʻe me SMM i ka multiple myeloma ikaika. ʻO ia ke kumu e nānā pinepine ai nā kauka i nā poʻe me SMM no nā hōʻailona e hiki ai ke lilo i maʻi kanesa ikaika.

He maʻi ʻaʻai anei (SMM)?

He nīnau paʻakikī kēia. ʻAʻole mālama ʻia ka SMM ma ke ʻano he maʻi kanesa ponoʻī. Eia nō naʻe, no ka mea hiki ke ulu aʻe i loko o kahi maʻi kanesa i kapa ʻia ʻo active multiple myeloma, ua manaʻo ʻia he mea mua ia no ke kanesa. E noʻonoʻo he wahi ʻokoʻa kou ma kou ʻili, he hōʻailona hānau. He hōʻailona mua paha ia o ka maʻi kanesa ʻili, ʻeā? ʻO ia ka SMM. ʻO ia hoʻi, he manawa kūpono kou e loaʻa ai ka myeloma maha. ʻO ia ke kumu e nānā pono ai nā kauka i nā poʻe me kēia maʻi .

Aia kekahi mau kūlana predisposing ʻē aʻe e hoʻopilikia ai i ka myeloma maha?

ʻAe, aia kekahi. Ua kapa ʻia ʻo Monoclonal Gammopathy of Undetermined Significance (MGUS) . E like me SMM, he kūlana kēia e hiki ke hana ma mua o ka ulu ʻana o ka myeloma maha. Manaʻo nā kauka ʻo MGUS (puana ʻia ʻo "M-gus") he mea mua ia no ka myeloma maha.

Pehea ka hopena o (SMM) i koʻu kino? He aha nā hōʻailona?

Eia ka mea nui: ʻO ka hapa nui o ka poʻe me (SMM) ʻaʻole hōʻike i kekahi mau hōʻailona.ʻO ia hoʻi, ʻaʻole paha ʻoe e manaʻo i kekahi ʻoluʻolu ʻole a ʻeha paha. ʻIke ka hapa nui o ka poʻe he SMM ko lākou ke hana ʻia kahi hoʻāʻo koko maʻamau no kekahi kumu ʻē aʻe. Hiki i kēlā mau hoʻāʻo koko ke hōʻike he ʻano protein ʻē kou i kapa ʻia ʻo nā protein M , i hana ʻia e nā cell plasma ʻē i loko o kou kino.

Hōʻike nā hoʻāʻo koko e hana ana kēia mau cell plasma maʻamau ʻole i nā protein pale maʻamau ʻole (nā protein M). Eia kekahi, inā ʻoe e hana i kahi biopsy iwi iwi, hiki i nā kauka ke ʻike i kēia mau cell plasma maʻamau ʻole i loko o ka iwi iwi. Eia nō naʻe, i loko o kēia wā "puhi", ʻaʻole pilikia ka myeloma i kou kino, no laila ʻaʻohe hōʻailona o ka poʻe me SMM.

ʻO wai ka mea hiki ke loaʻa (SMM)? He maʻi maʻamau anei kēia?

Hoʻopilikia pinepine kēia maʻi i ka poʻe ma luna o 60 mau makahiki. ʻO ka awelika o ka makahiki i ka wā i ʻike ʻia ai ka maʻi ma waena o 62 a me 67 mau makahiki.

ʻAʻole he maʻi maʻamau ka (SMM). Manaʻo nā kānaka noiʻi e hoʻopilikia wale ia i hoʻokahi i loko o 100,000 poʻe. Eia nō naʻe, hoʻopilikia wale ka myeloma multiple i ʻehiku i loko o 100,000 poʻe. No laila, ʻoi aku ka laha ʻole o ka (SMM).

He aha ka pilikia o ka ulu ʻana (SMM) i loko o ka myeloma maha ikaika?

He mea nui hoʻi kēia e ʻike. I loko o nā makahiki ʻelima mua ma hope o ka ʻike ʻia ʻana me SMM, ma kahi o 10% o ka poʻe me SMM e loaʻa i ka myeloma multiple ikaika i kēlā me kēia makahiki. I loko o nā makahiki ʻelima e hiki mai ana, hāʻule kēlā pakeneka i 3% i kēlā me kēia makahiki. Ma hope o nā makahiki 10 mua, hāʻule hou kēia pilikia i 1% i kēlā me kēia makahiki.

ʻO ke ʻano kēia, ʻaʻole e loaʻa i nā kānaka a pau me (SMM) ka myeloma maha. Eia nō naʻe, aia kahi pilikia, no laila he mea nui loa ka nānā mau ʻana i nā kauka.

Aia kekahi mau hoʻokolohua e hiki ke wānana pololei inā e loaʻa i kekahi ka myeloma maha?

ʻO ka mea pōʻino, ʻaʻohe hoʻāʻo i kēia manawa e hiki ke wānana pololei inā e loaʻa i kekahi ka myeloma multiple. Ke hoʻomau nei nā kauka a me nā mea noiʻi i ke kālailai ʻana i nā loli genetic e pili ana me ka myeloma multiple a ke nānā nei e ʻike inā hiki iā lākou ke ʻike inā e loaʻa i kekahi me SMM ka myeloma multiple.

He aha nā kumu no ka puka ʻana mai o (SMM)?

Ua ʻike nā kānaka noiʻi he mau hōʻailona ko nā pūnaewele plasma ʻano ʻē a me nā mea i kapa ʻia ʻo M protein no ka myeloma maha (MM) a me ka myeloma maha (MM). Eia naʻe, ʻaʻole lākou i ʻike pono i ke kumu e lilo ai nā pūnaewele plasma maʻamau a olakino i mea ʻē. Ke noiʻi nei lākou i kekahi mau kumu kūpono:

• Nā hoʻololi hoʻoilina: Ke nānā nei nā kānaka noiʻi inā he pilina ma waena o nā loli i kekahi mau genes (oncogenes - nā genes e paipai i ka ulu ʻana o nā cell) a me ka myeloma maha (MM).
• Momona: Aia kekahi manaʻo he kumu paha ka momona o ke kino nui.

Pehea e ʻike ai (SMM)? He aha ke ʻano o nā hoʻokolohua e hana ʻia?

Hiki i nā kauka ke hana i kekahi mau hoʻokolohua e hōʻoia inā loaʻa iā ʻoe kēia maʻi. E hoʻomanaʻo, inā hōʻike kahi hoʻāʻo koko a/a i ʻole mimi maʻamau i nā hōʻailona o ka protein M, ʻo ia paha ka hōʻailona mua e loaʻa iā ʻoe ka myeloma maha. A laila e hana nā kauka i kekahi mau hoʻokolohua kumu e ʻike ai inā e holomua ana kou maʻi i ka myeloma maha. Hiki i kēia mau hoʻokolohua ke komo pū me:

• Helu Koko Piha (CBC): Ke ana kēia i ka helu o nā hunaola koko ʻulaʻula, nā hunaola koko keʻokeʻo, a me nā platelet i hana ʻia e kou iwi iwi.
• Hoʻāʻo kemika koko: Nānā kēia i kou pae creatinine (e nānā i ka hana maikaʻi o kou mau puʻupaʻa), ka pae albumin (e nānā i ka hana maikaʻi o kou mau puʻupaʻa a me ke akepaʻa), a me ka pae calcium (e nānā i ka nalowale o ka iwi).
• Hoʻāʻo immunoglobulin helu: Ke ana kēia hoʻāʻo koko i nā pae o nā protein M (nā protein pale) i loko o kou koko.
• Electrophoresis a me ka immunofixation serum: Ke nānā nei kēia mau hoʻokolohua i nā protein M i loko o kou koko.
• Nā hoʻāʻo mimi: Hiki i nā kauka ke noi iā ʻoe e hōʻiliʻili i ka mimi ma ka home no 24 mau hola e nānā i nā protein M.
• Nā kukuna X: Hoʻohana ʻia nā kukuna X e ʻike inā he pōʻino iwi ma muli o ka myeloma maha.
• ʻO ke kiʻikuhi Computed Tomography (CT): ʻO kēia kekahi ala e ʻike ai i ka pōʻino o ka iwi.
• ʻO ke Kiʻi Resonance Magnetic (MRI): Hoʻohana kēia hoʻāʻo i nā nalu lekiō a me nā magnet ikaika e hana i nā kiʻi kikoʻī o kou mau iwi a me ka iwi kuamoʻo. Hiki ke hoʻohana ʻia kēia hoʻāʻo e ʻimi i nā hōʻike o ka hōʻino mua ʻana o ka iwi.
• Nā biopsies iwi iwi: Hiki i nā kauka ke lawe i kahi laʻana o kou iwi iwi a kālailai iā ia e ʻike i ka pakeneka o nā cell plasma maʻamau a me nā mea ʻē aʻe i loko. Hiki iā lākou ke nānā i ka laʻana iwi iwi no nā loli i kāu DNA e hiki ke alakaʻi i ka maʻi kanesa.

He aha nā pae hoʻohālikelike no (SMM)?

Ke kamaʻilio nā kauka e pili ana i nā "kumu hoʻohālikelike," ʻo ia hoʻi nā hopena hoʻāʻo e kū ana i nā kūlana lapaʻau e pono ai e hana i kahi hōʻailona. ʻO nā kumu hoʻohālikelike no (SMM):

• He hoʻāʻo koko e hōʻike ana i kahi pae o ka protein M ʻoi aku ma mua o 3g/dl (3 grams no ka deciliter o ke koko).
• He hoʻāʻo mimi 24-hola e hōʻike ana i 500 milligrams a ʻoi aku paha o ka protein. A i ʻole...
• Hōʻike ka biopsy iwi iwi he 10% a me 59% o nā hunaola koko āpau i loko o kou iwi iwi nā hunaola plasma. A...
• ʻAʻohe hōʻailona o nā ʻeha iwi ʻē a i ʻole ka hōʻino ʻana o nā puʻupaʻa i hiki ke hana ʻia e ka myeloma, ua maʻamau ka helu o kāu mau cell koko, a ua maʻamau kou mau pae calcium.

Pehea e mālama ʻia ai kēia maʻi?

I kēia manawa, ʻo ke ʻano maʻamau no SMM he "kali makaʻala." Pili kēia i nā kauka e hana ana i nā hoʻokolohua maʻamau e nānā i nā pae o ka protein M i loko o kou koko a me nā pae o nā cell plasma i loko o kou iwi iwi. E like me ke kiaʻi, ke nānā nei lākou e ʻike inā e ʻoi aku ka ʻino o ka maʻi.

Loaʻa paha i kekahi poʻe kahi pilikia kiʻekiʻe o ka loaʻa ʻana o ka myeloma multiple ikaika. I kēlā mau hihia, paipai paha kekahi mau kauka e hoʻomaka i ka mālama ʻana i ka myeloma multiple i ka wā mua. Inā loaʻa iā ʻoe ka myeloma multiple (MM), ʻo kāu kauka ke kanaka maikaʻi loa e hāʻawi iā ʻoe i ka ʻike a me nā ʻōlelo aʻoaʻo lapaʻau āu e pono ai.

Hiki iaʻu ke hōʻemi i ka pilikia o ka hoʻomohala ʻana (SMM)?

ʻO ka mea pōʻino, ʻaʻohe ala i ʻike ʻia i kēia manawa e pale aku ai i ka hoʻokumu ʻia ʻana o (SMM).

ʻEhia ka lōʻihi e hiki ai iā ʻoe ke ola me (SMM)?

He ʻokoʻa ke ʻano o ka hopena o kēia maʻi i kēlā me kēia kanaka. Loaʻa paha i kekahi poʻe akā ʻaʻole loa e loaʻa ka myeloma multiple. Loaʻa i kekahi poʻe ka myeloma multiple i nā mahina a i ʻole nā ​​​​makahiki ma hope o ka ʻike ʻia ʻana. Inā hopohopo ʻoe e pili ana i ka noho ʻana me SMM, e nīnau i kāu kauka i ka mea hiki iā ʻoe ke manaʻo. ʻO lākou ka poʻe maikaʻi loa e hāʻawi iā ʻoe i ka ʻike kikoʻī.

ʻEhia ka lōʻihi e hiki ai iā ʻoe ke ola me ka myeloma maha?

He pilikia nō hoʻi kēia no nā kānaka he nui. Ma kahi o 40% a 82% o ka poʻe me ka myeloma maha e ola ana i ʻelima mau makahiki ma hope o ka hōʻoia ʻana. Aia kēia i nā kumu he nui, me ke ʻano o ka maʻi a me ka pane ʻana i ka lāʻau lapaʻau.

Pehea e hiki ai iaʻu ke mālama i koʻu olakino?

Inā loaʻa iā ʻoe ka myeloma he nui, ʻaʻole paha ʻoe e pono koke i ka lāʻau lapaʻau - a i ʻole. E haʻi aku kāu kauka iā ʻoe e hele mai no nā nānā maʻamau. ʻO kēia ke nānā inā ua loli kou kūlana i ka myeloma he nui. Hiki i ka noho ʻana me ka myeloma he nui ke kaumaha a hoʻonāukiuki i ka hopohopo . Manaʻo paha ʻoe, "Auē, makemake wau e hiki iaʻu ke hana i kekahi mea e pili ana i kēia." He mea maʻamau kēlā. Akā aia kekahi mau mea hiki iā ʻoe ke hana e mālama i kou olakino holoʻokoʻa:

• E ʻai i ka meaʻai kaulike. Inā kānalua ʻoe no kēia, e kūkākūkā me kahi meaʻai meaʻai.
• Inā he mea puhi paka ʻoe, e ʻoluʻolu e hoʻāʻo e haʻalele.
• E hoʻomaha pono.
• E pale iā ʻoe iho mai nā maʻi. E nīnau i kāu kauka e pili ana i nā ala e pale aku ai i nā maʻi.
• E hoʻoikaika kino i nā manawa a pau.Akā, e kamaʻilio mua me kāu kauka a nīnau i ke ʻano o ka hoʻoikaika kino kūpono iā ʻoe a me ka nui o kāu e hana ai. ʻAʻole maikaʻi hoʻi ka hana nui ʻana.
• E makaʻala hoʻi i kou olakino noʻonoʻo. Inā ʻoe e kaumaha a kaumaha paha no kou kūlana, e kamaʻilio me kāu kauka e pili ana i ia mea. E hōʻoia e haʻi iā lākou, ʻoiai inā ʻoi aku ka lōʻihi o ke kaumaha a i ʻole ke kaumaha ma mua o ʻelua pule a i ʻole e hoʻopilikia i kāu mau hana o kēlā me kēia lā.

He aha nā nīnau e pono iaʻu e nīnau aku i kaʻu kauka?

Inā loaʻa iā ʻoe (SMM), eia kekahi mau nīnau hiki iā ʻoe ke nīnau i kāu kauka:

• No ke aha i hiki mai ai kēia iaʻu?
• Pehea kēia e pili ai i koʻu ola o kēlā me kēia lā?
• ʻEhia ka manawa e hoʻomohala ai ka myeloma maha?
• Aia kekahi mau hōʻailona kikoʻī e hōʻike ana i ka myeloma maha, a he pono anei iaʻu e ʻike iā lākou?
• Aia kekahi mau lāʻau lapaʻau e pale ai i ke kūlana (SMM) mai ka ulu ʻana i ka myeloma maha?

ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai (Leka Lawe-Home)

ʻO ka Smoldering Multiple Myeloma (SMM) kahi maʻi pre-cancerous o ka myeloma multiple (MM). Eia naʻe, ʻaʻole nā ​​​​kānaka a pau me SMM e loaʻa i ka myeloma multiple active. Makemake pinepine ka poʻe me SMM e ʻike inā e loaʻa iā lākou ka myeloma multiple active, a inā pēlā, i ka manawa hea. He mau nīnau paʻakikī loa kēia e pane. ʻAʻole i loaʻa i nā kauka nā pane a pau.

Eia nō naʻe, ua hōʻike ʻia nā noiʻi hou ma o ke kaha kiʻi ʻana i nā loli i kekahi mau genes, hiki paha ke wānana i kekahi ʻano inā e ulu aʻe (SMM) i ka myeloma maha, a inā pēlā, i ka manawa hea.

Inā loaʻa iā ʻoe kēia maʻi, e nīnau i kāu kauka inā he ʻike hou e pili ana i kou maʻi. E hauʻoli nui lākou e kōkua iā ʻoe. ʻO ka mea nui loa, ʻo ia ka hahai ʻana i nā ʻōlelo aʻoaʻo a kāu kauka a noho ikaika i ka noʻonoʻo.

ʻO ka Myeloma Multiple e puhi ana, SMM, Multiple Myeloma, maʻi kanesa, maʻi koko, iwi ʻiʻo, protein M, maʻi kanesa koko, nā pūnaewele plasma