Ua kiʻekiʻe anei kou helu platelet? E kamaʻilio kākou e pili ana i ka Thrombocytosis!

Ua lawe anei ʻoe i kāu hōʻike Helu Koko Piha a nānā i nā mea i ʻōlelo ʻia? Ua ʻike paha ʻoe aia kahi waiwai i kapa ʻia ʻo "Platelets" ma waena o nā mea ma laila. I kekahi manawa ʻōlelo ke kauka, "Ua kiʻekiʻe iki kou helu platelet." I kēlā manawa, he mea maʻamau ke manaʻo iki i ka makaʻu a me ka hopohopo. "He aha kēia? He mea koʻikoʻi anei?" Manaʻo ʻoe. No laila i kēia lā, e kamaʻilio maʻalahi a aloha kākou e pili ana i kēia hoʻonui ʻana o nā platelets koko, ʻo ia hoʻi kahi kūlana i kapa ʻia ʻo Thrombocytosis ma ka ʻōlelo lapaʻau.

ʻO ka mea mua, e nānā kākou, he aha nā platelets?

I nā huaʻōlelo maʻalahi, he ʻano ʻāpana liʻiliʻi nā platelets i loko o ko kākou koko. E noʻonoʻo iā lākou he 'hui kōkua' liʻiliʻi e hele mai e hoʻōki i ke kahe ʻana o ke koko ke loaʻa iā ʻoe kahi ʻoki a i ʻole kahi ʻōpala ma kekahi wahi o kou kino. Hele koke lākou i kahi o ka ʻeha, pili pū, a hana i kahi clot, e like me ka plaster, e sila i ka ʻeha. Penei ke ʻano o ka pau ʻana o ke kahe ʻana o ke koko. No laila hiki iā ʻoe ke ʻike he ʻāpana koʻikoʻi a koʻikoʻi loa nā platelets o ko kākou kino.

Akā, e like me nā mea āpau, hiki ke kū mai nā pilikia ke piʻi nui kēia mau platelets. ʻO ka Thrombocytosis ka wā e piʻi ai ka nui o nā platelets i loko o ke koko ma luna o ka pae maʻamau. Ke piʻi aʻe nā platelets ma kēia ʻano, hiki i ko kākou koko ke lilo i mea pipili i kekahi manawa. Hiki i kēia ke alakaʻi i nā ʻōpū koko i makemake ʻole ʻia e hana ana ma nā wahi i ʻole ai ka ʻeha, ʻo ia hoʻi, i loko o nā kīʻaha koko. Inā ʻaʻole mālama ʻia kēia mau ʻōpū koko, hiki iā lākou ke alakaʻi i nā kūlana koʻikoʻi e like me ka hōʻeha puʻuwai a i ʻole ka hahau.

ʻElua mau ʻano nui o ka thrombocytosis:

Ma muli o ke kumu o ka helu kiʻekiʻe o nā platelet i loko o kou koko, hiki ke hoʻokaʻawale ʻia kēia ʻano i ʻelua ʻano nui. He mea nui e hoʻomaopopo i kēia mau mea ʻelua, no ka mea, e pili ana nā ʻano lapaʻau i kēia ʻano.

Eia nō naʻe, inā hōʻike kāu hoʻāʻo koko ua kiʻekiʻe ka helu o kāu platelet, ʻo ia hoʻi ke hana nei kekahi mea i loko o kou kino e pono ai ke noiʻi ʻia e ke kauka. Ma muli o ke kumu o ka ʻike, pono paha ʻoe i ka lāʻau lōʻihi, ka lāʻau pōkole, a i ʻole ka lāʻau ʻole.

He aha nā hōʻailona o ka helu platelet kiʻekiʻe?

ʻO kaʻoiaʻiʻo, ʻaʻole ʻike ka nui o ka poʻe i kekahi mau hōʻailona o ka helu platelet kiʻekiʻe. ʻIke ʻia ia ma ka hanana ke hana ʻia kahi hoʻāʻo koko no kekahi kumu ʻē aʻe.

Inā loaʻa iā ʻoe ka Reactive Thrombocytosis, hiki iā ʻoe ke ʻike i nā hōʻailona o ke kūlana kumu (no ka laʻana, ke kuni mai kahi maʻi).

Eia nō naʻe, inā ʻo ka piʻi ʻana o nā platelets ke kumu o ka hana ʻana o nā ʻūpā koko a i ʻole (kākaʻikahi loa) ke kahe koko i loko, hiki ke loaʻa kekahi mau hōʻailona. ʻIke pinepine ʻia kēia ʻano ma ka Essential Thrombocytosis.

• Luhi
• Ka kahe pinepine ʻana o ka ihu
• Ke kahe koko (bruising) ʻoiai ma hope o kahi ʻeha liʻiliʻi
• Ke kahe koko maʻalahi mai nā ʻāʻī a i ʻole nā ​​​​wahi ʻē aʻe i loko o ka waha
• Pōʻino , ʻike maka pōwehiwehi, a me ke poʻo ʻeha
• ʻEha, pehu, a me ka ʻulaʻula ma nā lima a me nā wāwae (he hōʻailona o kahi maʻi i kapa ʻia ʻo erythromelalgia)
• ʻEha ʻōpū, ʻoi aku hoʻi ma ka ʻaoʻao ʻākau o luna o ka ʻōpū (hiki ke hōʻailona o kahi maʻi e like me ka Budd-Chiari syndrome)

No ke aha e piʻi ai nā platelets penei? He aha nā kumu?

ʻOkoʻa nō hoʻi nā kumu ma muli o nā ʻano ʻelua a mākou i kūkākūkā ai ma mua.

Nā kumu o ka Thrombocytosis Koʻikoʻi (ET)

Hoʻokumu ʻia kēia e nā hoʻololi genetic. Akā, ʻaʻole kēia he mea i hānau ʻia me ia, akā he mea e ulu ana i ka hala ʻana o ka manawa. I ka ʻōlelo maʻalahi, aia kahi loli i loko o nā genes e haʻi ana i ko mākou kino e hana i nā platelets. ʻO ka hopena, hoʻomaka ka iwi iwi e hana i nā platelets he nui me ka ʻole o ke kaohi.

Nā kumu o ka Thrombocytosis Reactive

ʻO kēia wale nō ka pane a ke kino i kahi pilikia ʻē aʻe. Eia kekahi mau kumu maʻamau o nā platelets kiʻekiʻe:

• Ke kahe koko ʻana: Ke nui ke koko i nalowale ma muli o kahi ulia a i ʻole ke ʻoki kino ʻana.
• Nā kūlana maʻi kanesa: Ma muli o kekahi mau ʻano maʻi kanesa.
• Nā maʻi: Nā maʻi bacteria a viral paha.
• Nā kūlana mumū: Nā maʻi e hoʻoulu ai i ka mumū i loko o ke kino, e like me ka arthritis.
• ʻAʻai anemia nele i ka hao.
• Kekahi mau lāʻau lapaʻau.
• Ka wehe ʻana i ka spleen ma ke ʻoki kino: ʻO kekahi o nā hana o ka spleen, ʻo ia ka wehe ʻana i nā platelets kahiko. Hiki i ka wehe ʻana ke hoʻonui i ka helu platelet.

He aha nā pilikia e hiki ke hana ma muli o kēia ʻano?

ʻOi aku ka nui o ka pilikia o ka poʻe me ka Essential Thrombocytosis (ET). He mea kākaʻikahi loa nā pilikia ma ka Reactive Thrombocytosis.

ʻO ka pilikia nui loa ka hoʻokumu ʻia ʻana o nā ʻūpā koko . Inā paʻa kēia mau ʻūpā koko i loko o kahi kīʻaha koko e alakaʻi ana i ka lolo, hiki iā lākou ke hana i ka hahau ʻana , a inā paʻa lākou i loko o kahi kīʻaha koko e alakaʻi ana i ka puʻuwai, hiki iā lākou ke hana i ka hōʻeha puʻuwai . Hiki i kēia mau ʻūpā koko ke hana ʻia ma nā wahi ʻē aʻe, e like me nā māmā a me nā wāwae.

He mea kākaʻikahi loa, hiki i ka ET ke ulu aʻe i nā maʻi ʻaʻai koko ʻē aʻe, e like me ka leukemia, a i ʻole ke kumu o ka ʻeha o ka iwi iwi (myelofibrosis). Hiki iā ia ke hoʻonui i ka pilikia o kekahi mau pilikia i ka wā hāpai.

Akā, mai hopohopo. Inā loaʻa iā ʻoe ka ET, e nānā pono ana kāu kauka i kou olakino a e hāʻawi iā ʻoe i ka lāʻau lapaʻau e pono ai e pale aku i nā pilikia e like me kēia.

Pehea e ʻike pono ai nā kauka i kēia?

ʻIke nui ʻia ka thrombocytosis ma o nā hoʻāʻo koko. ʻO ka maʻamau, ʻo ka helu platelet ma mua o 450,000 i kēlā me kēia microliter o ke koko ua manaʻo ʻia he kiʻekiʻe. Makemake paha kāu kauka e hoʻāʻo hou i kou koko ma hope o kekahi mau pule e ʻike ai inā kiʻekiʻe mau ana kāu helu platelet. Inā ua hoʻi ka helu i ka maʻamau, ʻaʻohe mea e hopohopo ai.

Inā hoʻomau ka helu platelet i ke kiʻekiʻe, ʻo ka hana aʻe e hoʻoholo ai inā he Reactive a i ʻole Essential. Pono kēia i kekahi mau hoʻokolohua hou aʻe.

• Nā hoʻāʻo koko ʻē aʻe: Nānā kēia i nā mea e like me nā pae hao a me nā māka mumū, a nānā i nā ʻano platelet ʻē ma lalo o kahi microscope.
• Nā hoʻāʻo hoʻoilina: Hiki i kēia hoʻāʻo ke ʻike i nā hoʻololi hoʻoilina e like me JAK2 , CALR1 , a i ʻole MPL1, i ʻike pinepine ʻia ma ka Essential Thrombocytosis.
• ʻO ka biopsy iwi: Pili kēia i ka lawe ʻana i kahi hāpana liʻiliʻi loa o ka iwi mai kahi wahi e like me ka iwi ʻūhā ma lalo o ka anesthesia a hoʻāʻo iā ia ma kahi keʻena hoʻokolohua. Hiki i kēia ke hōʻoia maopopo i ke kūlana ET.

Pehea e mālama ʻia ai?

Hoʻopili ʻia nā koho lapaʻau i ke ʻano o ka thrombocytosis āu e loaʻa ai a me kāu mau hōʻailona.

No ka Thrombocytosis Reactive:

ʻO kēia ka manawa e piʻi ai nā platelets i ka pane ʻana i kahi maʻi ʻē aʻe. No laila, kuhikuhi ʻia ka lāʻau lapaʻau i ke kumu kumu . No ka laʻana, inā piʻi ka helu platelet ma muli o kahi maʻi, ke hāʻawi ʻia nā antibiotics no kēlā maʻi, e hoʻi ka helu platelet i ka maʻamau i ka wā e ho'ōla ai ka maʻi.

No ka Thrombocytosis Koʻikoʻi (ET):

ʻAʻole hiki ke ho'ōla ʻia ka ET. Eia nō naʻe, hiki ke mālama pono ʻia e hōʻemi i ka pilikia o nā ʻūpā koko. Aia kekahi mau koho lapaʻau:

• Ke kali makaʻala: Inā ʻaʻohe ou hōʻailona a haʻahaʻa kou pilikia o ke kūkulu ʻana i nā ʻūpā koko, hiki i kāu kauka ke nānā i kou kūlana ma ka hana ʻana i nā hoʻokolohua koko maʻamau me ka ʻole o ke kuhikuhi ʻana i kekahi lāʻau lapaʻau.
• ʻAspirin haʻahaʻa: Hiki ke kuhikuhi ʻia iā ʻoe kahi pila aspirin i kēlā me kēia lā e kōkua i ka pale ʻana i nā ʻūpā koko. Akā e hoʻomanaʻo, mai hoʻomaka e lawe i ka aspirin ma kāu iho me ka ʻole o ke kūkākūkā ʻana me ke kauka.
• Nā lāʻau lapaʻau e hoʻohaʻahaʻa i nā pae platelet: ʻO nā lāʻau lapaʻau e like me Hydroxyurea, Anagrelide, a me Interferon alfa e kāohi i ka hana ʻana o ka platelet.
• Ke kaʻina hana wehe platelet: Inā he pilikia koke ka hoʻomohala ʻana i kahi ʻōpū koko e hoʻoweliweli ana i ke ola, hiki ke hoʻoili ʻia kou koko ma o kahi mīkini e kānana i nā platelet keu.

Āhea ʻoe e ʻike ai i ke kauka?

Inā ua ʻike ʻia ʻoe me ka thrombocytosis, he mea nui e loaʻa nā hoʻāʻo koko maʻamau e like me ke kuhikuhi a kāu kauka. Eia kekahi, e nīnau i kāu kauka i nā hōʻailona āu e hōʻike koke ai inā loaʻa.

ʻO ke ʻano kūikawā, inā loaʻa iā ʻoe nā hōʻailona o ka hahau ʻana a i ʻole ka hōʻeha puʻuwai (e like me ka ʻeha koke o ka umauma, ka paʻakikī i ka ʻōlelo ʻana, ka nāwaliwali ma kekahi ʻaoʻao o ke kino, ke kūlou ʻana o ka maka), e hele koke i ka Emergency Department (ETU) o ka haukapila.