Aia ke koko i loko o ka mimi? E aʻo kākou e pili ana i kēia maʻi kanesa o ka ʻōnaehana mimi (Urothelial Carcinoma)

Ua ʻike anei ʻoe ua loli ke kala o kou mimi, me he mea lā he koko iki i loko? A i ʻole ke ʻeha nei ʻoe i ka mimi pinepine ʻana, ka ʻeha hope, a pēlā aku? ʻOiai ke manaʻo nei mākou he mau maʻi ʻaʻai mimi maʻalahi (UTIs), i kekahi manawa hiki iā lākou ke lilo i hōʻailona o kahi mea ʻoi aku ka koʻikoʻi. I kēia lā e kamaʻilio mākou e pili ana i kekahi ʻano maʻi, ʻo ia hoʻi ke kanesa o ke ala mimi. Mai hopohopo, e kamaʻilio mākou e pili ana i nā mea āpau ma nā ʻōlelo maʻalahi.

He aha ka Urothelial Carcinoma?

I ka ʻōlelo maʻalahi, ʻo Urothelial Carcinoma kahi ʻano maʻi kanesa e ulu ana i loko o kā mākou ʻōnaehana mimi. Ua kapa ʻia hoʻi ʻo ia ʻo Transitional Cell Carcinoma . I kēia manawa ke noʻonoʻo nei paha ʻoe i ke ʻano o "Urothelium". Pili ia i kahi membrane cell pale kūikawā e hoʻopili ana i kā mākou ʻōnaehana mimi, ʻo ia hoʻi, ka ʻōpū mimi, nā ʻōmole e lawe ana i ka mimi mai nā puʻupaʻa a i ka ʻōpū mimi (ureters), a me nā ʻāpana o nā puʻupaʻa kahi e hōʻiliʻili ai ka mimi. E like me ka pale wai ma nā paia o ko mākou hale, ʻo ka hana o kēia membrane cell ka pale ʻana i ka mimi mai ka launa pū ʻana me ke koena o ko mākou kino. No laila, i ka wā e ulu kūpono ʻole ai nā cell i loko o kēia membrane cell pale a lilo i cancerous, kapa mākou iā ia ʻo Urothelial Carcinoma.

ʻO kahi nīnau a ka poʻe he nui e nīnau ai, inā paha he maʻi ʻaʻai mimi kēia. ʻO ka ʻoiaʻiʻo, 90% o nā maʻi ʻaʻai mimi he ʻano kēia. Eia nō naʻe, hiki ke ulu i loko o nā puʻupaʻa. ʻO ka mea maikaʻi loa, hiki ke hoʻōla loa ʻia kēia maʻi ʻaʻai inā ʻike mua ʻia .

He aha nā ʻano nui o kēia maʻi kanesa?

Hiki ke hoʻokaʻawale ʻia kēia maʻi ʻaʻai i kekahi mau ʻano nui ma muli o ke ʻano o kona ulu ʻana a me kona laha ʻana. He mea nui loa kēia hoʻokaʻawale ʻana i ka hoʻoholo ʻana i ka lāʻau lapaʻau.

No ke aha e ulu ai kēia ʻano maʻi kanesa? He aha nā kumu pilikia?

ʻOiai ʻaʻole i ʻike nā kānaka ʻepekema i ke kumu kikoʻī, ua ʻike lākou i kekahi mau kumu e hoʻonui ai i ka pilikia o ka hoʻomohala ʻana i kēia maʻi kanesa.

• Ka puhipaka a me ka hoʻohana ʻana i ka paka: ʻO kēia ke kumu nui a nui loa o ka pilikia . Hele nā ​​​​kemika carcinogenic i loko o nā cigarettes ma ke koko a hōʻiliʻili i loko o ka mimi. Hoʻopōʻino kēia mau kemika ʻawahia i nā membrane cell pale o ka ʻōnaehana urinary, e hoʻomākaukau ana i ke ala no ka ulu ʻana o ka maʻi kanesa.
• Ka ʻike ʻia ʻana i nā kemika ma kahi hana: ʻOi aku ke kiʻekiʻe o kēia pilikia no ka poʻe e hana ana ma nā wahi e hana ana i kekahi mau kala, laholio, nā lole, nā mea ʻili, a me nā lako hana lauoho.
• Nā maʻi ʻōpū mimi pinepine: Inā loaʻa iā ʻoe nā maʻi ʻōpū mimi (UTI) no ka manawa lōʻihi a hoʻohana paha i nā catheters no ka manawa lōʻihi, hiki i ka mumū ke hōʻino i nā cell a hoʻonui i kou pilikia o ka maʻi kanesa.
• Lapaʻau Radiation: ʻO ka lāʻau lapaʻau radiation i ka ʻōpū no nā maʻi ʻaʻai ʻē aʻe a me kekahi mau lāʻau anticancer (e like me ka cyclophosphamide) hiki ke hoʻonui i ka pilikia.
• Mōʻaukala ʻohana: ʻOi aku ke kiʻekiʻe o ka pilikia inā loaʻa kekahi o ka ʻohana i kēia ʻano maʻi kanesa a i ʻole he mau kūlana genetic e like me Lynch syndrome.
• Nā kumu ʻē aʻe: ʻO ka ʻelemakule a me ke kāne kekahi mau kumu pilikia. ʻOi aku ka maʻamau o kēia maʻi kanesa i nā kāne ma mua o nā wahine.

Pehea ʻoe e ʻike ai inā loaʻa iā ʻoe kēia maʻi?

Inā loaʻa iā ʻoe nā hōʻailona, ​​e hana mua kāu kauka i nā mea e like me ka hoʻāʻo mimi. A laila, inā kānalua ʻia ka maʻi ʻaʻai, hana pinepine ʻia kēia mau hoʻāʻo.

I kekahi manawa, inā maopopo loa i ke kauka he puʻupuʻu, e hana ʻo ia i kahi ʻoki kino i kapa ʻia ʻo TURBT (Transurethral Resection of Bladder Tumor) ma lalo o ka anesthesia ma ka haukapila. Ma kēia, ʻoki loa ʻia ka puʻupuʻu a wehe ʻia i ka wā o ka cystoscopy a hoʻouna ʻia no ka hoʻāʻo ʻana. Lawe ʻia kekahi ʻāpana liʻiliʻi o ka ʻiʻo e ʻike inā ua pālahalaha ke kanesa i nā ʻiʻo.

Inā kiʻekiʻe ke ʻano o ke kanesa a invasive paha, hiki i ke kauka ke ʻōlelo aku i kahi scan CAT e ʻike inā ua pālahalaha aku i nā ʻāpana ʻē aʻe o ke kino.

Loaʻa iā ʻoe kēia mau hōʻailona pū kekahi? (Nā hōʻailona)

ʻO ka hōʻailona maʻamau o kēia maʻi kanesa, ʻo ia ke koko i loko o ka mimi . Hiki ke ʻike ʻia he poni, ʻalani, a ʻulaʻula ʻeleʻele paha, akā ʻaʻole paha e ʻike mau ʻia.

Eia kekahi, e ʻike i kēia mau hiʻohiʻona:

• ʻEha a wela paha i ka wā e mimi ai
• Pono e mimi pinepine ma mua o ka maʻamau
• ʻEha mau ma kekahi ʻaoʻao o ke kua
• Manaʻo luhi no ke kumu ʻole (fatigue)
• Ka emi ʻana o ke kaumaha
• Ke manaʻo nei i kahi mea e like me kahi puʻupuʻu i loko o ka ʻōpū a i ʻole ka puʻupaʻa
• Malaise a me ke kuni haʻahaʻa

E nā wāhine, e akahele loa!

I nā manawa he nui, ke ʻike nā wāhine i nā hōʻailona e like me ke kuni ʻana a i ʻole ka mimi pinepine ʻana, manaʻo lākou he maʻi maʻi urinary tract (UTI) wale nō ia. Eia nō naʻe, i kekahi manawa he hōʻailona ia o ka maʻi ʻaʻai mimi. Ua hōʻike ʻia nā noiʻi ua ʻike ʻia nā wāhine me kēia maʻi ma hope o nā kāne.

E aʻo kākou e pili ana i nā pae o ka maʻi ʻaʻai.

Hoʻoholo ʻia ke kahua e ka mamao o ka laha ʻana o ke kanesa i loko o ke kino. He mea nui loa kēia i ke koho ʻana i ka lāʻau lapaʻau.

He aha nā lāʻau lapaʻau no kēia?

Nui nā lāʻau lapaʻau kūpono no kēia maʻi kanesa. He maʻalahi loa ka lāʻau lapaʻau, ʻoiai inā ʻike mua ʻia. Hoʻoholo ʻia ke ʻano o ka lāʻau lapaʻau e ke ʻano, ke ʻano, a me ke kahua o ke kanesa.

• ʻO ke ʻoki kino:
• TURBT: E like me ka mea i ʻōlelo ʻia ma luna, hiki ke hoʻopau loa ʻia nā ʻōpū mua me kēia ʻano hana.
• Cystectomy: Inā ua pālahalaha ke kanesa i nā ʻiʻo a inā ua hoʻi mai ke kanesa me ke kiʻekiʻe kiʻekiʻe, pono paha e wehe ʻia ka ʻōpū mimi holoʻokoʻa. A laila, e hoʻomohala ʻia nā ala ʻē aʻe e hoʻokahe ai i ka mimi. E wehewehe kāu kauka i kēia iā ʻoe.

• Kemokalama:
• ʻO ka Intravesical Chemotherapy: Ma hope o ke ʻoki ʻana o TURBT, hoʻokomo pololei ʻia nā lāʻau anticancer i loko o ka ʻōpū mimi ma o kahi paipu. Hiki i kēia ke kōkua i ka pale ʻana i ka hoʻi hou ʻana mai o ke kanesa.
• ʻŌnaehana Chemotherapy: Inā ua pālahalaha ke kanesa, hāʻawi ʻia ka chemotherapy i ke kino holoʻokoʻa ma o kahi aʻa (IV).

• Lapaʻau Radiation: No ke kanesa i pālahalaha i nā ʻiʻo, hoʻohana ʻia nā kukuna ikehu kiʻekiʻe e luku i nā hunaola kanesa inā makemake ʻia ke ʻoki ʻana e wehe i ka ʻōpū mimi.

• Hoʻōla lāʻau pale:He lāʻau lapaʻau holomua loa kēia i kēia manawa. ʻO ka mea a mākou e hana ai, ʻo ia ka hoʻoulu ʻana i ka ʻōnaehana pale o ko mākou kino ponoʻī e hakakā i nā hunaola kanesa. Hāʻawi pololei ʻia kekahi mau lāʻau lapaʻau i loko o ka ʻōpū mimi, a hāʻawi ʻia kekahi mau lāʻau lapaʻau holomua (nā mea pale checkpoint) ma o kahi aa koko. Ua loaʻa nā hopena maikaʻi loa i kēia mau mea.

• Lapaʻau Kūikawā: ʻAʻole like kēia me ka chemotherapy kuʻuna. Ua hoʻolālā ʻia kēia mau lāʻau lapaʻau e ʻike i nā hiʻohiʻona kikoʻī o nā hunaola kanesa a hoʻouka wale iā lākou. He ʻano lapaʻau hou a holomua hoʻi kēia e hoʻohana ʻia nei.