He aha ka Wilms Tumor? Aia kāu keiki i ka pilikia? E makaʻala kākou!

Pehea kou manaʻo inā ʻoe e ʻauʻau ana, e ʻaʻahu ana, a e paʻa wale ana paha i kāu keiki liʻiliʻi a ʻike ʻoe i kahi puʻupuʻu liʻiliʻi ma ko lākou ʻōpū? He mea weliweli maoli kēlā, ʻeā? I nā manawa e like me kēia, pono mākou e noʻonoʻo e pili ana i kēia maʻi i kapa ʻia ʻo ka puʻupuʻu ʻo Wilms. E kamaʻilio wale kākou e pili ana i kēia lā.

He aha maoli ka Wilms Tumor?

I ka ʻōlelo maʻalahi, ʻo ka puʻupuʻu Wilms kahi ʻano maʻi ʻaʻai puʻupaʻa e loaʻa ana i nā keiki ʻōpio. ʻO ia ka 90 pakeneka o nā maʻi ʻaʻai puʻupaʻa i nā keiki. I kekahi manawa, hiki ke loaʻa pū ka puʻupuʻu Wilms me nā kūlana ʻē aʻe i loaʻa i ka wā hānau. Kāhea mākou i kēia mau "congenital syndromes" a i ʻole he hōʻiliʻili o nā kūlana i loaʻa i ka wā hānau.

Ua kapa ʻia hoʻi kēia ʻo `(Wilms' tumor)` a me `(nephroblastoma)`. ʻO ka hapa pinepine, hoʻokahi wale nō tumor i loko o hoʻokahi puʻupaʻa. Eia nō naʻe, hiki i kekahi mau keiki ke loaʻa nā tumors ma nā puʻupaʻa ʻelua `(bilateral),` a i ʻole hiki ke ʻoi aku ma mua o hoʻokahi wahi kanesa i loko o hoʻokahi puʻupaʻa.

ʻO wai ka mea e loaʻa nui ana i kēia?

He maʻi laha ʻole kēia e pili ana i nā pākeke. ʻO ka puʻupuʻu Wilms kahi maʻi ʻaʻai e pili nui ana i nā keiki ma lalo o 15 mau makahiki. 95% o nā keiki me kēia maʻi i ʻike ʻia ma mua o 10 mau makahiki.

ʻOi aku ka nui o ka pilikia o nā keiki ʻeleʻele o ka hanauna ʻApelika. ʻOi aku ka haʻahaʻa o ka pilikia o nā keiki ʻĀsia. Eia kekahi, ʻoi aku ka nui o ka pilikia o nā kaikamahine e loaʻa iā ia ma mua o nā keikikāne.

Ma kahi pakeneka liʻiliʻi loa o nā ʻohana, ua hōʻike ʻia hoʻi kēia he mea i loaʻa mai nā genes.

Pehea ka maʻamau o kēia ʻano?

Ma kahi ʻāina e like me ʻAmelika, ua ʻōlelo ʻia he 500 mau hihia hou o ka puʻupuʻu Wilms i hōʻike ʻia i kēlā me kēia makahiki. He mea paʻakikī ke loaʻa nā helu kikoʻī e pili ana i kona ʻano ma Sri Lanka, akā he maʻi ʻaʻai kēia e ʻike ʻia i waena o nā keiki.

He aha nā maʻi hānau e hiki ke ʻike ʻia me ka maʻi Wilms?

He mea kākaʻikahi loa i nā keiki me ka puʻupuʻu Wilms ke loaʻa nā maʻi hānau ʻē aʻe. Akā hiki ke hana ʻia. Eia kekahi o nā syndromes nui:

• ʻO ka maʻi Beckwith-Wiedemann: ʻO nā keiki me kēia maʻi he 5% a 10% ka pilikia o ka loaʻa ʻana o ka puʻupuʻu Wilms. He kūlana kēia e ulu nui ai nā ʻāpana o ke kino ma mua o ka maʻamau. I kekahi manawa ʻoi aku ka nui o kekahi ʻaoʻao o ke kino ma mua o kekahi.
• ʻO ka maʻi WAGR: Loaʻa i nā keiki me kēia maʻi he 50% ka pilikia o ka loaʻa ʻana o ka puʻupuʻu Wilms (ʻo ka W ma ka inoa ke kū nei no Wilms). Hiki i kēia ke kumu o ka nalowale hapa o ka iris (Aniridia), a me nā pilikia genital a me nā puʻupaʻa.
• ʻO ka maʻi Denys-Drash:ʻO nā keiki me kēia hui pū ʻana o nā hōʻailona he kiʻekiʻe loa ka pilikia o ka hoʻomohala ʻana i ka maʻi Wilms, hiki ke hana i nā pilikia me nā ʻōpū hānau a me nā puʻupaʻa.

He aha nā hōʻailona o ka maʻi Wilms?

E nānā i kēia mau hōʻailona i kāu keiki:

• He puʻupuʻu a paʻa paha/puʻupuʻu i loko o ka ʻōpū. Hiki i kēia puʻupuʻu a puʻupuʻu paha ke ʻeha i kekahi manawa, akā i ka hapanui o ka manawa ʻaʻole ia he ʻeha.
• ʻEha ʻōpū.
• Ke koko i loko o ka mimi (hematuria).
• Kuni.
• Ke koko kiʻekiʻe (hypertension). Hiki i kēia ke hoʻoulu i ke kahe ʻana o ka ihu, ka ʻeha poʻo, a me nā maka ʻulaʻula i loko o ke keiki.

Inā loaʻa iā ʻoe kekahi a ʻoi aku paha o kēia mau hōʻailona , ​​​​pono ʻoe e ʻike koke i ke kauka.

He aha ke kumu o ka maʻi Wilms?

ʻO kaʻoiaʻiʻo, ʻaʻole mākou i ʻike pono i ke kumu o ka puʻupuʻu Wilms. ʻOiai he kakaikahi loa ka poʻe i loaʻa kahi predisposition genetic, ʻaʻole maopopo ke kumu e ulu ai i ka hapa nui o nā hihia.

Pehea e ʻike ʻia ai ka maʻi ʻo Wilms?

Inā ʻike ʻoe i kahi puʻupuʻu ma kahi o ka diaper o kāu pēpē, a inā paha ke kumu o ka puʻupuʻu iā ʻoe e hoʻohana i kahi diaper nui aʻe, makemake paha kāu kauka e hoʻāʻo no kahi puʻupuʻu Wilms. I kekahi manawa hiki i kēia mau puʻupuʻu ke ʻoi aku ka nui ma mua o ka puʻupaʻa.

Inā loaʻa i kāu keiki kekahi o nā syndromes a mākou i kūkākūkā ai ma mua a i ʻole he pilikia genetic, hiki iā ʻoe ke kamaʻilio me kāu kauka a hoʻoholo inā e hoʻomau i ka hoʻāʻo ʻana.

ʻO nā hoʻokolohua i hoʻohana ʻia no ka ʻike ʻana i ka maʻi Wilms:

• Ka hoʻokolokolo kino: I loko o kēia, nānā pono ke kauka i ka ʻōpū o ke keiki.
• Nā hoʻāʻo kiʻi:
• ʻO ke kiʻi ʻana o ka ultrasound ʻōpū.
• CT scan - Hana pinepine ʻia kēia ma ke komo ʻana i kahi wai kūikawā (ʻokoʻa).
• Hiki paha i ke kauka ke hana i kahi X-ray umauma a i ʻole CT scan e ʻike ai inā ua metastasized ke kanesa i nā māmā.
• Hiki i kēia mau hoʻokolohua kiʻi ke kōkua i ka hoʻoholo ʻana inā he puʻupuʻu kāu keiki. Hiki iā lākou ke kōkua i ka hoʻokaʻawale ʻana ma waena o ka puʻupuʻu Wilms a me kekahi ʻano maʻi ʻaʻai puʻupaʻa.
• Nā hoʻāʻo koko a me ka mimi: ʻO kēia mau mea e pili ana i nā hoʻāʻo hana ate a me nā hoʻāʻo clotting koko.
• Biopsy: Pili kēia i ka lawe ʻana i kahi ʻāpana liʻiliʻi o ka ʻiʻo mai ka puʻupuʻu a hoʻouna iā ia i kahi lab no ka hoʻāʻo ʻana.

He aha kāu e pono ai e ʻike e pili ana i ke ana o ka maʻi kanesa?

ʻElua ala e hoʻoholo ai i ke kahua o ka puʻupuʻu Wilms, ʻo ia hoʻi, pehea ka mamao o ka laha ʻana o ke kanesa. Ua kapa ʻia kēia he "staging." ʻO ke kiʻekiʻe o ka helu, ʻo ka nui o ka laha ʻana o ke kanesa.

Hoʻohana nā kauka ma nā ʻāina ʻEulopa i ka ʻōnaehana International Society of Pediatric Oncology (SIOP). Hoʻohana nā kauka ma ʻAmelika Hui Pū ʻIa a me Kanada i ka ʻōnaehana Children's Oncology Group (COG).

ʻO ka ʻokoʻa hoʻokahi ma waena o kēia mau ʻano hana ʻelua, ʻo ia ke ʻano COG, nānā ʻia ke kahua o ka puʻupuʻu ma hope o ke ʻoki ʻana a ma mua o ka hāʻawi ʻana i ka chemotherapy (nā lāʻau anti-cancer). Ma ke ʻano SIOP, hana ʻia ke ʻoki ʻana ma hope o ka chemotherapy a nānā ʻia ke kahua ma hope o kēlā.

Ua māhele ʻia nā pae ma lalo o ka ʻōnaehana COG penei:

• Pae I: Aia ka puʻupaʻa ma ka puʻupaʻa o ke keiki a hiki ke wehe loa ʻia me ke ʻoki ʻana.
• Pae II: Ua ulu ka puʻupuʻu mai loko mai o ka puʻupaʻa, akā hiki ke wehe loa ʻia me ke ʻoki ʻana.
• Pae III: ʻAʻole hiki ke wehe loa ʻia ka puʻupuʻu. Noho nā hunaola kanesa i loko o ka ʻōpū o ke keiki (lua ʻōpū).
• Pae IV: Ua pālahalaha ke kanesa ma waho o ka ʻōpū a me ke pelvis o ke keiki i nā wahi ʻē aʻe, e like me nā māmā, ke akepaʻa, nā iwi, a me ka lolo.
• Pae V: Aia ka puʻupuʻu ma nā puʻupaʻa ʻelua (bilateral). I kēia pae, nānā nā kauka i ke pae o nā puʻupaʻa ʻelua ma ke kaʻawale.

Pehea e mālama ʻia ai ka maʻi ʻo Wilms?

Hoʻomaʻamaʻa pinepine ʻia ka puʻupuʻu Wilms me ka hui pū ʻana o ke ʻoki kino a me ka chemotherapy. I kekahi manawa hiki ke hoʻohana ʻia ka radiation therapy.

Hiki paha i nā keiki me nā puʻupuʻu haʻahaʻa ka pilikia, kahi i laha ʻole ai ke kanesa a hiki ke wehe loa ʻia ke puʻupuʻu, ke hana ʻoki kino wale nō. I kekahi manawa, hiki ke hāʻawi ʻia ka chemotherapy ma mua o ke ʻoki kino e hoʻēmi i ka puʻupuʻu, e palekana ai ke ʻoki kino.

Hoʻohana pinepine ʻia ka chemotherapy ma o ka intravenous (IV). Hiki ke hana ʻia kēia ma ke ʻano outpatient a i ʻole ma kahi haukapila.

Hiki i kāu keiki ke loaʻa nā hopena ʻaoʻao mai ka chemotherapy a i ʻole ka radiation therapy. Inā hana ʻia kēia, e hōʻoia e haʻi i kāu kauka. Aia nā mea hiki iā ʻoe ke hana e hōʻemi i nā hopena ʻaoʻao a me nā lāʻau lapaʻau hiki iā ʻoe ke hāʻawi i kāu keiki.

Hiki ke pale ʻia ka maʻi ʻōpū o Wilms?

ʻAʻohe mea hiki iā ʻoe a i ʻole kāu keiki ke hana e hoʻoulu ai a pale aku paha i ka maʻi ʻōpū Wilms. He mea kēia ma waho o ko mākou mana.

He aha ka wānana no kekahi kanaka me ka puʻupuʻu Wilms?

ʻO ka wānana no ka puʻupuʻu Wilms ma ka hapanui o nā hihia he maikaʻi loa ia. ʻO ka hopena maʻamau he maikaʻi loa ia, ʻoiai inā hiki i ke kauka ke wehe loa i ka puʻupuʻu a ʻaʻole i laha ka maʻi kanesa ma kahi ʻē aʻe o ke kino. Eia nō naʻe, aia kahi manawa liʻiliʻi e "hoʻi hou" ai ka puʻupuʻu Wilms.

Hiki i ka maʻi Wilms ke lilo i mea make?

ʻOiai hiki ke mālama pono ʻia ka puʻupuʻu Wilms me ka hui pū ʻana o ke ʻoki kino, chemotherapy, a/a i ʻole ka radiation therapy,He maʻi kanesa nō kēia. No laila, hiki ke make. ʻO ia ke kumu he mea nui e ʻike mua iā ia a hoʻomaka i ka lāʻau lapaʻau.

He aha ka nui o ke ola no ka maʻi Wilms tumor?

Ma kahi o 90% o ka poʻe i ʻike ʻia me ka puʻupuʻu Wilms e ola mau ana ma hope o ʻelima mau makahiki. Hiki ke ʻokoʻa iki kēia helu ma muli o nā mea e like me ke kahua o ke kanesa, ka nui o ka puʻupuʻu, a me ke ʻano o nā hunaola kanesa ma lalo o kahi microscope (histology). ʻOiai ua ʻōlelo ʻia ma mua he haʻahaʻa ka pilikia o ka hoʻi hou ʻana o nā keiki ma lalo o 2 mau makahiki, ʻaʻole nui ka makahiki i kēia manawa ma mua o ka wā ma mua.

Āhea wau e ʻike ai i kaʻu kauka e pili ana i ka maʻi puʻupuʻu Wilms?

Inā e mālama ʻia ana kāu keiki no ka puʻupuʻu Wilms, e ʻike i kāu kauka inā he mau hopohopo a nīnau paha kāu. ʻOi loa aku inā ʻike ʻoe i kekahi mau hōʻailona hou a inā paha e ʻoi aku ka ʻino o kekahi mea, e hoʻomaopopo koke iā lākou.

I kou wā e mālama ʻia ai, e haʻi aku kāu hui lapaʻau iā ʻoe i nā mea e makaʻala ai, e like me nā hōʻailona o nā maʻi ʻaʻai mimi. Inā hana ʻia kēia, pono paha ʻoe e hele i ka lumi pilikia.

Pono nō hoʻi ke keiki e hele no nā kipa hahai ma nā manawa maʻamau e hōʻoia i ko lākou olakino maikaʻi. Hiki paha i ke kauka ke kuhikuhi i ke keiki i kahi loea puʻupaʻa (nephrologist) a i ʻole kahi loea ʻōnaehana mimi (urologist).

Pehea e hiki ai iaʻu ke kōkua i kaʻu keiki e noho olakino ma hope o ka mālama ʻia no ka maʻi puʻupuʻu Wilms?

He mea nui i kāu keiki ke hana i kēia mau mea:

• E inu i nā wai e lawa ai e kōkua i kou mau puʻupaʻa e hana pono.
• E kaupalena i ka hoʻohana ʻana i nā lāʻau lapaʻau e like me ka aspirin, ibuprofen, a me ka naproxen. E kamaʻilio me ke kauka o kāu keiki e pili ana i nā huahana i emi iki ka hōʻeha ʻana i nā puʻupaʻa o kāu keiki.
• E nānā i kou koko i nā manawa maʻamau.

He ʻeha anei ka puʻupuʻu Wilms?

I kekahi manawa hiki ke ʻeha ka puʻupuʻu Wilms, akā, ʻaʻole ia he ʻeha mau.

He aha ka ʻokoʻa ma waena o ka puʻupuʻu Wilms (nephroblastoma) a me ka neuroblastoma?

ʻOiai ke kani like nei kēia mau huaʻōlelo ʻelua, ʻelua ʻano maʻi kanesa e hoʻomaka ana i ʻelua ʻano like ʻole o nā cell. ʻO Nephroblastoma kahi maʻi kanesa o nā puʻupaʻa. ʻO Neuroblastoma kahi maʻi kanesa e hoʻomaka ana i nā cell nerve. Hoʻomaka pinepine ia i loko o nā kelepa adrenal, akā hiki iā ia ke hoʻouka i nā puʻupaʻa. Loaʻa nā ʻano maʻi kanesa ʻelua i nā keiki, a hiki i nā mea ʻelua ke hōʻike ma ke ʻano he puʻupuʻu i loko o ka ʻōpū. No laila, he mea nui e loaʻa kahi hōʻailona pololei.

Inā ua ʻike ʻia kāu keiki me ka puʻupuʻu Wilms, e ʻōlelo paha kāu kauka e hoʻokaʻaʻike aku ʻoe i kahi kikowaena lapaʻau e loea ana i ka mālama ʻana i nā maʻi kanesa o nā kamaliʻi. ʻOiai he mea kakaikahi ka puʻupuʻu Wilms, he maʻi hiki ke mālama ʻia. Hiki paha i kāu keiki ke kūpono e komo i kahi hoʻokolohua lapaʻau. Nui nā keiki me ka puʻupuʻu Wilms i kākau inoa ʻia i kēia papahana. ʻO ka nui o nā holomua i ka mālama ʻana i ka puʻupuʻu Wilms ka hopena o kēia mau hoʻokolohua lapaʻau.

ʻO ka mea nui loa (Leka Lawe-Home)

ʻAe, ua kamaʻilio nui kākou e pili ana i ka puʻupuʻu Wilms, ʻeā? ʻO ka mea nui e hoʻomanaʻo ai, inā ʻike ʻoe i kekahi mau puʻupuʻu a i ʻole nā ​​​​pehu ʻē aʻe ma ka ʻōpū o kāu keiki, mai hopohopo a e ʻike koke i ke kauka.

• He maʻi ʻaʻai ka puʻupuʻu ʻo Wilms e ulu ana i loko o nā puʻupaʻa o nā keiki ʻōpio.
• ʻOiai ʻaʻole ʻike ʻia ke kumu maoli o kēia, aia paha kekahi mana genetic.
• Inā ʻike koke ʻia a mālama pono ʻia, ʻoi aku ka kiʻekiʻe o ka manawa e ho'ōla ai.
• ʻO ke ʻoki kino, ka chemotherapy, a i kekahi manawa ka radiation therapy nā lāʻau lapaʻau nui.
• ʻOiai ma hope o ka lāʻau lapaʻau, he mea nui loa e hahai pono i nā ʻōlelo a ke kauka a hele i nā nānā kino i nā manawa i hoʻonohonoho ʻia.

Mai makaʻu. Ua holomua loa ka ʻepekema lapaʻau i kēia lā. ʻO ka mea nui loa, ʻo kou nānā a me ka hana wikiwiki. Makemake au i kāu keiki e ola koke!

ʻO ka puʻupuʻu Wilms, nephroblastoma, ka maʻi kanesa o nā kamaliʻi, ka maʻi kanesa o nā puʻupaʻa, ke olakino o nā keiki, nā hōʻailona o ka maʻi kanesa, ka mālama ʻana i ka maʻi kanesa