Koj puas muaj kev tsis haum tshuaj rau nqaij liab? Cia peb kawm txog Alpha-gal Syndrome!

Koj puas tau xav tias yog vim li cas koj thiaj li muaj cov tsos mob ua xua tom qab noj cov nqaij liab xws li nqaij nyuj, nqaij npuas, lossis tshis? Tej zaum koj yuav mob pob khaus, lossis koj yuav mob plab, lossis koj yuav ua pa nyuaj. Tej zaum nws yuav zoo li txawv txawv, tab sis qhov tseeb nws ua tau. Hnub no peb yuav tham txog ib qho kev ua xua txawv txawv, tab sis tseem ceeb heev. Nws hu ua Alpha-gal Syndrome.

Alpha-gal Syndrome yog dab tsi? Cia peb nkag siab yooj yim!

Hais yooj yim xwb, Alpha-gal Syndrome (AGS) yog ib hom kev ua xua rau zaub mov hnyav thiab txawv txawv uas tshwm sim thaum koj noj nqaij liab los ntawm cov tsiaj txhu (piv txwv li, nqaij nyuj, nqaij npuas, tshis, nqaij nyuj qus). Nws feem ntau tshwm sim tom qab raug tom los ntawm qee hom kab laum, tshwj xeeb tshaj yog tias koj tau raug tom ntau zaus. Raws li koj paub, kab laum yog cov kab me me uas txuas rau tsiaj thiab nqus lawv cov ntshav.

Tam sim no saib, qee cov kab laum muaj cov carbohydrate molecule hu ua alpha-gal hauv lawv cov qaub ncaug. Thaum cov alpha-gal molecule no nkag mus rau hauv peb cov ntshav tom qab tom kab laum, nws tuaj yeem ua rau peb lub cev rhiab heev rau cov nqaij liab. Qhov tshwm sim yog tias peb lub cev tiv thaiv kab mob paub tias cov nqaij liab yog ib yam dab tsi ua rau lub cev puas tsuaj thiab pib ua rau nws. Ib yam li tus yeeb ncuab. Qhov ntawd yog qhov ua rau cov tsos mob ntawm kev ua xua. Cov neeg uas muaj AGS tuaj yeem ua xua tsis yog rau cov nqaij liab xwb, tab sis kuj rau lwm yam khoom uas muaj alpha-gal, piv txwv li, qee cov tshuaj thiab xab npum.

Tu siab kawg li, tam sim no tsis muaj tshuaj kho tau AGS. Tab sis tsis txhob txhawj. Koj tuaj yeem nrog koj tus kws kho mob tham kom nrhiav tau txoj hauv kev kom tsis txhob muaj teeb meem thiab noj qab nyob zoo.

Cov molecule no hu ua Alpha-gal yog dab tsi?

Alpha-gal yog ib hom carbohydrate, lossis yog ib hom suab thaj, uas pom muaj nyob rau hauv cov hlwb ntawm ntau hom tsiaj txhu. Tab sis nws tsis yog tsim tawm ntuj tsim los ntawm tib neeg lub cev. Yog vim li ntawd peb lub cev thiaj li ntxhov siab thaum nws raug tom los ntawm tus kab laum.

Cov khoom noj thiab cov khoom lag luam twg muaj Alpha-gal?

Tej yam uas muaj alpha-gal suav nrog:

• Nqaij liab: Tej yam xws li nqaij npuas, nqaij nyuj, luav, nqaij yaj, tshis, nyuj qus, thiab nqaij nyuj qus.
• Cov khoom siv kho mob thiab tshuaj: Piv txwv li, cov tshuaj Cetuximab, uas yog siv rau mob qog noj ntshav.
• Cov khoom ua los ntawm cov tsiaj txhu: gelatin, mis nyuj, nrog rau qee cov xab npum, tshuaj pleev, thiab cov khoom siv hauv tsev yuav muaj cov no.

Xav txog seb, txawm tias cov ice cream lossis cheese uas koj noj kuj muaj me ntsis alpha-gal no. Yog li koj yuav tsum ceev faj heev.

Tsis tas li ntawd xwb, qee tus neeg uas muaj AGS yuav tsis haum rau cov khoom uas muaj cov tshuaj hu ua carrageenan. Carrageenan yog ib yam khoom uas feem ntau siv los ua kom cov khoom noj tuab thiab khaws cia. Nws tuaj yeem pom muaj nyob rau hauv cov khoom xws li mis txiv ntoo, cov khoom nqaij, thiab mis nyuj yogurt.

Leej twg thiaj muaj tau tus mob Alpha-gal Syndrome?

Qhov no tuaj yeem tshwm sim rau txhua tus neeg, txawm tias yog ib tus neeg uas tsis tau muaj kev ua xua rau nqaij liab dua li. Txawm li cas los xij, feem ntau nws pom muaj rau cov neeg laus.

Cov neeg uas siv sijhawm ntau nyob rau sab nraum zoov uas muaj cov kab laum ntau, xws li cov chaw cog qoob loo thiab cov hav zoov, muaj feem yuav kis tau tus kab mob AGS ntau dua. Hauv Sri Lanka, nws kuj zoo rau cov neeg ua haujlwm hauv cov chaw xws li hav zoov lossis cov liaj teb uas muaj tsiaj txhu kom paub txog qhov no.

Cov kab mob dab tsi ua rau muaj AGS?

Hauv Tebchaws Meskas, tus kab laug sab hnub qub yog tus kab laug sab uas feem ntau cuam tshuam nrog AGS. Txawm li cas los xij, muaj lwm hom kab laug sab uas tuaj yeem ua rau nws nyob rau ntau qhov chaw ntawm lub ntiaj teb. Piv txwv li:

• Kab laug dub nyob hauv Asmeskas
• "Cayenne tick" hauv Central America
• Tus kab laug sab Asian longhorned nyob rau hauv Asia

Qhov tseem ceeb tshaj plaws yog yuav tsum ceev faj yog tias koj raug tom los ntawm ib tug kab laum thiab nrhiav kev pab kho mob yog tias tsim nyog.

Puas muaj lwm lub npe rau tus mob Alpha-gal Syndrome no?

Yog, qhov no muaj ntau lub npe ntxiv:

• Kev ua xua rau Alpha-gal
• Kev ua xua rau nqaij ntawm cov tsiaj txhu
• Kev ua xua rau nqaij liab
• Kev ua xua rau nqaij tom

Dab tsi ua rau muaj tus mob Alpha-gal Syndrome? Vim li cas qhov no thiaj tshwm sim?

Qhov mob no tau piav qhia thawj zaug hauv xyoo 2009. Nws yog tshwm sim los ntawm kev tom ntawm cov kab uas nqa ib lub molecule hu ua alpha-gal hauv lawv cov qaub ncaug. Thaum feem ntau lwm yam kev ua xua rau zaub mov yog tshwm sim los ntawm cov protein, qhov no yog tshwm sim los ntawm ib lub molecule carbohydrate (qab zib), yog li nws siv sijhawm ntev rau qhov kev ua xua kom tshwm sim. Qhov ntawd txhais tau tias cov tsos mob feem ntau tshwm sim ntawm ob thiab rau teev tom qab noj nqaij liab . Qhov no xav tias yog vim peb lub cev siv sijhawm ntev dua los zom cov carbohydrates dua li cov protein.

Cov kws kho mob tseem tsis tau paub meej tias vim li cas alpha-gal no ua rau muaj kev tsis haum rau nqaij liab lossis tshuaj kho mob qog noj ntshav Cetuximab uas tau hais los saum toj no. Ib yam li ntawd, vim li cas qee tus neeg thiaj li muaj AGS thaum lwm tus tsis muaj tseem tab tom tshawb nrhiav.

Cov tsos mob ntawm Alpha-gal Syndrome yog dab tsi?

Cov tsos mob ntawm qhov no tuaj yeem sib txawv heev. Ib txhia neeg yuav muaj cov tsos mob me me xwb, thaum lwm tus yuav muaj cov tsos mob hnyav heev, uas ua rau tuag taus.

Cov kev tsis haum tshuaj ntawm daim tawv nqaij feem ntau yog:

• Khaus tawv nqaij heev (cov kws kho mob hu ua pruritus)
• Tawv nqaij liab thiab o (tseem hu ua flushing)
• Cov tawv nqaij ua pob khaus, cov hlwv uas zoo li mob qaib ntxhw (qhov no hu ua urticaria lossis hives)
• O ntawm daim di ncauj, qhov muag, caj pas, tus nplaig, lossis lub ntsej muag (qhov no hu ua angioedema)

Cov teeb meem ntawm lub plab zom mov kuj tuaj yeem tshwm sim, qee zaum tsuas yog cov no:

• Mob plab, mob plab
• Mob raws plab
• Mob plab, mob plab zom mov tsis zoo
• Kev zom zaub mov tsis zoo, mob plab zom mov tsis zoo (dyspepsia)
• Mob nqaij ntshiv
• Xeev siab los yog ntuav

Alpha-gal syndrome kuj tseem ua rau muaj cov tsos mob ntsig txog lub ntsws. Cov no yog cov txaus ntshai heev:

• Anaphylaxis: Qhov no yog qhov txaus ntshai tshaj plaws. Kev ua xua hnyav heev uas tuaj yeem ua rau ua tsis taus pa thiab ua rau tuag taus. Yog tias koj ua tsis taus pa, mus rau tsev kho mob ze tshaj plaws tam sim ntawd lossis hu rau 911.
• Hnoos
• Ua pa nyuaj, ua pa luv luv (dyspnea)
• Ua pa nrov nrov

Tej zaum yuav muaj lwm cov tsos mob:

• Mob pob qij txha (qhov no tsis tshua muaj ntau)
• Lub plawv dhia ceev ceev, zoo li koj lub hauv siab dhia ceev ceev
• Ntshav siab qis (hypotension)
• Mast cell activation syndrome, ib qho teeb meem tsis tshua muaj ntawm lub cev tiv thaiv kab mob (tseem tsis tshua muaj)

Puas muaj lwm yam uas cuam tshuam rau cov tsos mob?

Yog, koj cov tsos mob yuav hloov pauv raws sijhawm. Kev ua xua yuav hnyav dua lossis tshwm sim ntau zaus dua yog tias koj raug tom los ntawm tus kab laum tshiab. Qee zaum, tej yam xws li kev haus dej cawv, kev ua ub ua no, thiab kev tawm dag zog kuj tseem tuaj yeem cuam tshuam rau koj lub cev teb rau alpha-gal.

Vim li cas Alpha-gal Syndrome thiaj nyuaj rau kuaj mob?

Qhov no yuav nyuaj me ntsis rau kev txheeb xyuas. Muaj ntau yam ua rau.

Ib qho yog tias cov kab laum tsis hnov ​​mob thaum lawv tom, yog li ntawd muaj coob tus neeg tsis paub tias lawv raug kab laum tom.

Tsis tas li ntawd xwb, tsis zoo li lwm yam khoom noj uas ua xua rau alpha-gal, qhov kev tsis haum rau alpha-gal yuav siv sijhawm ntau teev los tsim . Qee zaum cov tsos mob tshwm sim thaum ib tag hmo tom qab noj hmo. Leej twg yuav xav tias nws yog vim cov nqaij uas lawv noj thaum sawv ntxov lossis thaum noj su?

Tsis tas li ntawd xwb, tsis yog txhua zaus noj alpha-gal, muaj kev tsis haum tshuaj, thiab cov tsos mob kuj tsis tshwm sim tib yam nkaus.

Vim yog cov yam no, nws yuav nyuaj me ntsis rau koj thiab koj tus kws kho mob kom paub seb qhov no puas yog lwm yam uas tsis yog alpha-gal.

Cov kws kho mob kuaj qhov no li cas tiag?

Yuav kom kuaj tau AGS, koj tus kws kho mob lossis tus kws kho mob ua xua yuav saib xyuas koj cov tsos mob, keeb kwm kev kho mob, thiab kev kuaj lub cev kom zoo. Tsis tas li ntawd, kev kuaj mob ua xua yuav raug ua los xyuas kom meej tias koj tau kuaj mob. Cov tseem ceeb suav nrog:

• Kev kuaj ntshav: Qhov no kuaj seb puas muaj cov tshuaj immunoglobulin-E antibodies (IgE) nyob rau hauv cov ntshav, uas peb lub cev tiv thaiv kab mob ua tawm tsam alpha-gal.
• Kev kuaj tawv nqaij: Hauv qhov no, me me ntawm cov allergen raug muab tso rau ntawm qhov chaw ntawm daim tawv nqaij kom pom tias puas muaj kev tsis haum tshuaj.

Yog koj xav tias koj muaj AGS, mus ntsib kws kho mob sai li sai tau. Thaum koj paub tseeb tias koj muaj mob sai npaum li cas, ces yuav yooj yim dua rau koj zam cov khoom ua xua thiab tiv thaiv kom tsis txhob muaj teeb meem ntxiv.

Puas muaj kev kho kom zoo tag nrho rau qhov no?

Raws li tau hais ua ntej lawm, tam sim no tsis muaj tshuaj kho tau Alpha-gal Syndrome. Tab sis tsis txhob txhawj. Yog tias kuaj pom ntxov, koj thiab koj tus kws kho mob tuaj yeem ua haujlwm ua ke los tsim ib txoj kev npaj tswj hwm uas haum rau koj cov kev xav tau.

Qhov no kho li cas?

Txoj kev kho mob tseem ceeb rau ib tus neeg uas muaj AGS yog kom tsis txhob noj cov khoom noj thiab cov khoom muaj alpha-gal kiag li . Tsis tas li ntawd xwb, cov tshuaj kuj raug muab los tswj cov tsos mob yog tias noj yam zoo li no tsis raug.

Cov kws kho mob yuav pom zoo kom siv cov tshuaj xws li tshuaj antihistamines lossis tshuaj adrenaline rau kev siv thaum muaj xwm txheej ceev. Hauv cov xwm txheej hnyav xws li anaphylaxis, cov tshuaj epinephrine no tuaj yeem cawm tau txoj sia. Lwm cov kev kho mob nyob ntawm koj cov tsos mob. Piv txwv li, cov tshuaj cromolyn haus yuav pab tau rau cov teeb meem zom zaub mov.

Kuv yuav ua li cas thiaj txo tau qhov kev pheej hmoo ntawm kev mob Alpha-gal Syndrome?

Txoj kev zoo tshaj plaws los tiv thaiv koj tus kheej tsis yog los ntawm AGS xwb, tab sis kuj los ntawm lwm yam kab mob uas kis los ntawm kab laum, yog kom tsis txhob raug kab laum tom . Muaj ntau yam uas koj ua tau los ua qhov no:

• Tsis txhob mus taug kev hauv hav zoov, thaj chaw muaj nyom, thiab thaj chaw uas muaj ntoo ntau, tshwj xeeb tshaj yog qhov chaw muaj tsiaj txhu. Tsis tas li ntawd, ceev faj thaum ua haujlwm hauv lub vaj.
• Npog kom zoo: Hnav khaub ncaws tes ntev, ris ntev. Muab thom khwm npog koj lub ris, hnav khau. Yog tias ua tau, siv lub kaus mom thiab hnab looj tes.
• Siv cov tshuaj tua kab: Siv cov tshuaj tua kab uas tau kev pom zoo los ntawm kws kho mob. Qee cov tshuaj siv tau rau ntawm cov khaub ncaws. Cov tshuaj uas muaj permethrin siv tau rau ntawm cov khaub ncaws.
• Tshawb xyuas seb puas muaj kab laum (Tick check):Tom qab koj rov qab los ntawm sab nraum zoov, xyuas koj tus kheej thiab koj cov tsiaj kom paub seb puas muaj kab laum. Nws kuj yog ib lub tswv yim zoo kom da dej.
• Yog koj pom ib tug kab laum, tshem nws tawm sai sai: Siv cov tweezers los tuav lub taub hau lossis lub qhov ncauj ntawm tus kab laum, thiab ua tib zoo rub nws mus rau saum ntuj yam tsis txhob tsoo nws. Tom qab ntawd muab tshuaj tua kab mob rau thaj chaw ntawd.

Yog tias koj muaj Alpha-gal Syndrome, koj yuav tsum tsis txhob noj dab tsi, haus dab tsi, thiab khoom dab tsi?

Muaj coob tus neeg uas muaj AGS yuav tsum tsis txhob noj nqaij liab thiab cov khoom noj uas muaj nqaij liab kiag li. Txawm li cas los xij, tsis yog txhua tus neeg yuav teb tau alpha-gal tib yam. Yog li ntawd , nws yog qhov zoo tshaj plaws los tham nrog koj tus kws kho mob lossis tus kws kho mob txog kev ua xua kom paub tseeb tias dab tsi ua rau koj ua xua.

Tej yam uas yuav tsum zam feem ntau yog:

• Nqaij liab: nqaij nyuj, nqaij yaj, tshis, nqaij venison, luav, nyuj qus, nqaij npuas.
• Cov khoom ua los ntawm nqaij liab: cov khoom noj ntxiv, mis nyuj, qab zib, ice cream, roj tsiaj (lard), cheese.
• Cov khoom siv tu tawv nqaij ua los ntawm nqaij: cov khoom muaj collagen, lanolin, gelatin, glycerin.
• Lwm cov khoom: Tham nrog koj tus kws kho mob txog cov tshuaj uas koj noj. Tsis tas li ntawd, cov qhov plawv los ntawm npua lossis nyuj, cov ntaub phais, thiab qee cov tshuaj tiv thaiv kab mob tuaj yeem ua rau muaj kev tsis haum tshuaj.

Yuav muaj dab tsi tshwm sim tom ntej? Peb yuav ua neej li cas nrog qhov no?

Yog koj ua raws li koj tus kws kho mob cov lus qhia kom zoo thiab zam tej yam uas ua rau koj ua xua, koj tuaj yeem nyob zoo nrog AGS. Koj tus kws kho mob yuav pab koj nrhiav txoj hauv kev los txo koj qhov kev pheej hmoo ntawm kev ua xua.

Qhov tseem ceeb tshaj plaws yog ua cov kauj ruam kom tsis txhob raug kab laum tom ntxiv , vim tias kev raug kab laum tom ntau zaus tuaj yeem ua rau kev ua xua hnyav dua.

Thaum twg koj yuav tsum nrhiav kev pab kho mob?

Yog tias koj muaj cov tsos mob ntawm AGS, mus ntsib kws kho mob lossis kws kho mob dav dav tam sim ntawd kom txoj kev npaj kho mob tuaj yeem tsim tau uas yog rau koj.

Cov Lus Qhia Txog Kev Coj Mus Tsev

Zoo, yog li Alpha-gal Syndrome (AGS) uas peb tau tham txog hnub no yog kev ua xua hnyav rau nqaij liab uas tshwm sim los ntawm kev tom ntawm kab laum. Nws tuaj yeem nyuaj me ntsis rau kev kuaj mob, vim tias cov tsos mob tshwm sim tom qab ob peb teev. Thiab tam sim no tsis muaj kev kho rau nws.

Tiamsis tsis txhob txhawj! Yog tias koj paub thaum ntxov, ua raws li koj tus kws kho mob cov lus qhia, tsis txhob noj cov khoom noj thiab cov khoom tsis zoo, thiab tiv thaiv koj tus kheej ntawm cov kab laum, koj kuj tuaj yeem noj qab nyob zoo. Yog tias koj muaj cov tsos mob no, nco ntsoov mus ntsib kws kho mob.

`Alpha-gal Syndrome, Kev ua xua rau nqaij liab, Cov kab mob uas kis los ntawm kab laum, Kev ua xua rau zaub mov, Cov tsos mob ntawm kev ua xua, Kev tiv thaiv los ntawm kab laum