Yog tias koj muaj ib tug neeg koj hlub uas muaj Down Syndrome hauv koj tsev neeg, nws yog ib qho ib txwm muaj ntau cov lus nug, thiab tej zaum txawm tias me ntsis ntshai, txog lawv txoj kev noj qab haus huv thaum lawv laus zuj zus. Tshwj xeeb, koj yuav tau hnov lub npe "Alzheimer's Disease" ntau heev. Tej zaum koj yuav tau xav ntau yam txog seb puas muaj kev sib txuas ntawm ob hom kab mob no. Tau kawg, muaj. Tab sis ua ntej koj ntshai, cia peb tham txog nws kom meej, yooj yim, thiab yooj yim.
Vim li cas cov neeg uas muaj Down syndrome thiaj li muaj feem yuav mob Alzheimer's ntau dua?
Yuav kom nkag siab qhov no, peb yuav tsum rov qab mus rau qhov yooj yim tshaj plaws ntawm peb lub cev. Cov ntawd yog peb cov chromosomes . Hais yooj yim, cov chromosomes no zoo li 'cov lus qhia' hauv txhua lub cell hauv peb lub cev. Txhua yam los ntawm peb cov xim plaub hau mus rau peb qhov siab yog txiav txim siab los ntawm cov noob caj noob ces uas cov chromosomes no muaj. Feem ntau, ib tus neeg muaj ob daim qauv ntawm txhua hom chromosome.
Txawm li cas los xij, ib tug neeg uas muaj Down syndrome muaj ib daim qauv ntxiv ntawm chromosome 21, uas yog, peb daim qauv . Nov yog li cas nws cuam tshuam nrog tus kab mob Alzheimer: Cov noob caj noob ces uas qhia kev tsim cov protein tsis zoo (beta-amyloid) uas tau tso rau hauv lub hlwb thaum tus kab mob Alzheimer tshwm sim nyob rau ntawm tib lub chromosome 21 no.
Yog li ntawd, vim muaj ib daim qauv ntxiv ntawm chromosome 21, ib tus neeg uas muaj Down syndrome tsim cov protein phem no ntau dua hauv lawv lub hlwb. Raws sijhawm, cov protein no sib sau ua ke thiab tso rau ntawm cov hlwb hlwb, ua rau cov hlwb ntawd puas tsuaj thiab pib rhuav tshem lawv. Qhov no yog qhov tshwm sim hauv tus kab mob Alzheimer.
Ntxiv mus, lub cev thiab lub hlwb ntawm cov neeg uas muaj Down syndrome laus sai dua li cov neeg feem ntau (laus ua ntej lub sijhawm) . Qhov ntawd yog, lub cev ntawm tus neeg hnub nyoog 45 xyoo uas muaj Down syndrome yuav zoo ib yam li lub cev ntawm tus neeg hnub nyoog 65 lossis 70 xyoo hauv cov pej xeem feem ntau. Qhov kev laus sai no kuj yog ib qho ua rau muaj tus kab mob Alzheimer's ntxov.
Cov tsos mob tshwm sim li cas? Puas txawv ntawm cov tsos mob ntawm tus kab mob Alzheimer's ib txwm muaj?
Yog lawm, qhov no yog ib qho tseem ceeb heev. Cov tsos mob ntawm tus kab mob Alzheimer hauv ib tus neeg uas muaj Down syndrome yuav txawv me ntsis ntawm cov tsos mob ntawm ib tus neeg ib txwm. Yog vim li ntawd nws thiaj li qee zaum nyuaj rau paub txog tus mob no.
Thaum peb xav txog Alzheimer's, peb feem ntau xav txog kev tsis nco qab. Tab sis rau ib tus neeg uas muaj Down syndrome, kev tsis nco qab tej zaum yuav tsis yog thawj cov tsos mob . Lwm yam kev hloov pauv yuav raug pom ua ntej.
Cia peb saib cov kev hloov pauv ntawd yog dab tsi nyob rau hauv lub rooj hauv qab no.
| Cov tsos mob | Nws zoo li cas rau ib tus neeg uas muaj Down syndrome |
|---|---|
| Ua haujlwm txhua hnub | Tej yam uas koj ua tau ib leeg xwb, xws li hnav khaub ncaws, noj mov, da dej, thiab ua tshuaj yej, xav tau kev pab. Qhov kev txaus siab thiab lub peev xwm ua tej yam ntawd maj mam ploj mus. |
| Kev hloov pauv tus cwj pwm | Ua cia li ntawd, lawv ua siab tawv, coj tus cwj pwm tsis tsim nyog, chim siab, lossis pib sawv ntsiag to, tsis muaj kev txaus siab rau sab tod, tsis hais lus. |
| Mob Qaug Dab Peg Tshiab | Qhov no yog ib qho tsos mob tseem ceeb heev. Yog tias ib tug neeg uas tsis tau muaj qaug dab peg hauv lawv lub neej pib muaj qaug dab peg tshiab tom qab hnub nyoog 40 xyoo, nws yuav yog ib qho cim qhia txog tus kab mob Alzheimer's. |
| Kev nco qab thiab kev xav | Txawm hais tias qhov kev poob nco qab yuav tsis pom tseeb thaum xub thawj, nws tuaj yeem tshwm sim raws sijhawm. Nws ua rau nyuaj rau nco qab tej yam tshiab. Lub peev xwm xaiv qhov yog los ntawm qhov tsis yog thiab txiav txim siab txo qis. |
| Nyuaj hais lus | Tej zaum koj yuav pib hais lus tsawg dua, muaj teeb meem nrhiav cov lus, lossis hais lus tsis meej. |
Qhov tseem ceeb tshaj plaws yog pom kev hloov pauv ntawm koj tus menyuam lossis tsev neeg tus cwj pwm ib txwm muaj (thawj qhov) . Vim tias lawv muaj qee qhov kev tsis taus ntawm kev kawm txij thaum yug los, nws tuaj yeem nyuaj rau paub txog kev hloov pauv hauv kev nco. Tab sis yog tias koj xav tias, "Tus neeg no tsis zoo li no ua ntej, thiab tam sim no lawv txawv," qhov ntawd yog qhov tseem ceeb tshaj plaws.
Thaum muaj hnub nyoog li cas, qhov kev pheej hmoo yuav nce ntxiv?
Kab mob Alzheimer feem ntau tshwm sim rau cov pej xeem tom qab hnub nyoog 65 xyoos. Txawm li cas los xij, rau ib tus neeg uas muaj Down syndrome, qhov kev pheej hmoo no tshwm sim ua ntej.
- Muaj hnub nyoog 35 xyooTsis ntev los no, cov kev tshawb fawb tau pom tias kwv yees li 25% (ib ntawm plaub) ntawm cov neeg uas muaj Down syndrome yuav muaj cov tsos mob ntawm Alzheimer's.
- Rau ntau tus neeg, cov tsos mob pib tshwm sim thaum lawv muaj hnub nyoog nruab nrab 40s lossis thaum ntxov 50s.
- Zuag qhia tag nrho, qhov yuav muaj ib tus neeg uas muaj Down syndrome yuav mob Alzheimer's yog peb mus rau tsib npaug ntau dua li cov pej xeem feem ntau.
Ua ib tug neeg saib xyuas, kuv yuav tsum ua li cas?
Cov ntaub ntawv no yuav ua rau koj ntshai. Tab sis tsis txhob ntshai. Kev paub txog yog riam phom zoo tshaj plaws. Muaj qee yam tseem ceeb heev uas koj ua tau.
1. Mus kuaj mob tsis tu ncua: Nws yog ib qho tseem ceeb uas yuav tsum coj koj tus menyuam lossis ib tug neeg hauv tsev neeg mus ntsib kws kho mob tsis tu ncua. Tshwj xeeb tshaj yog tom qab hnub nyoog 30 xyoo, tham nrog koj tus kws kho mob txog qhov kev pheej hmoo ntawm Alzheimer's.
2. Kev Ntsuam Xyuas Thaum Pib: Thaum koj muaj hnub nyoog 30 xyoo, nrog koj tus kws kho mob tham txog koj tus menyuam txoj kev nco, kev ua haujlwm txhua hnub, thiab tus cwj pwm. Qhov no yuav pab koj txheeb xyuas tej kev hloov pauv yav tom ntej.
3. Ua tib zoo saib xyuas tej kev hloov: Koj paub nws zoo tshaj plaws. Yog li ntawd, txawm tias tej kev hloov me me uas koj pom los xij, sau cia rau hauv ib phau ntawv nrog hnub tim thiab sijhawm. Sau tej yam xws li, "Nws tsis tuaj yeem hnav nws nkawm khau ib leeg hnub no," "Nws chim heev txij li lub lim tiam dhau los." Qhov no yuav pab tau tus kws kho mob heev.
4. Nrhiav kev kho mob tam sim ntawd: Yog tias koj muaj ib lossis ntau yam tsos mob teev saum toj no, tsis txhob tos kom txog thaum lig mam li mus ntsib koj tus kws kho mob . Txawm hais tias tus kab mob Alzheimer's tsis tuaj yeem kho tau tag nrho, muaj ntau yam kev kho mob thiab cov tswv yim uas tuaj yeem pab tswj cov tsos mob, txhim kho lub neej zoo, thiab muab kev pab rau koj thiab tus neeg mob.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Cov neeg uas muaj Down syndrome muaj feem yuav mob Alzheimer's ntau dua li cov pej xeem feem ntau.
- Cov tsos mob feem ntau pib thaum muaj hnub nyoog 40 xyoo lossis thaum ntxov 50 xyoo, ua ntej dua li cov pej xeem feem ntau.
- Es tsis txhob poob kev nco, cov tsos mob thawj zaug yuav suav nrog kev hloov pauv tus cwj pwm, tsis muaj peev xwm ua tiav cov haujlwm txhua hnub, lossis qaug dab peg tshiab.
- Yog tias koj pom muaj kev hloov pauv pom tseeb hauv koj tus neeg hlub tus cwj pwm, peev xwm, lossis kev coj ua txhua hnub, nco ntsoov nrog koj tus kws kho mob tham txog qhov ntawd.
- Kev kuaj pom thaum ntxov thiab kev tswj hwm kev kho mob kom zoo tuaj yeem txhim kho tus neeg mob lub neej zoo dua thiab muab kev pab rau koj ua tus saib xyuas.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus