Koj lossis ib tug neeg hauv koj tsev neeg puas muaj mob plawv tsis ua haujlwm? Los yog koj puas muaj lub plawv dhia ceev dhau? Yog tias muaj, koj tus kws kho mob yuav tau qhia koj txog ib hom tshuaj hu ua 'Cardiac Glycosides', thiab tej zaum yuav tau sau ntawv rau koj. Txawm hais tias lub npe no yuav zoo li nyuaj me ntsis, tsis txhob txhawj. Hnub no, peb yuav tham txog hom tshuaj no hauv txoj kev yooj yim thiab tus phooj ywg.
Hauv lus yooj yim, cov glycosides hauv lub plawv no yog dab tsi?
Hais yooj yim xwb, cov no yog ib pawg tshuaj uas pab cov neeg uas muaj tej yam mob plawv. Lawv tuaj yeem muaj cov tshuaj ntsiav, tshuaj ntsiav me me, lossis kua. Koj tus kws kho mob feem ntau yuav sau ntawv kom noj ib zaug ib hnub, tib lub sijhawm txhua hnub.
Cov tshuaj 'Cardiac Glycoside' uas paub zoo tshaj plaws thiab siv ntau tshaj plaws ntawm peb hauv Sri Lanka yog Digoxin . Tej zaum koj twb tau txais cov tshuaj no lawm.
Cov tshuaj no ua haujlwm li cas hauv lub cev?
Txawm hais tias qhov no yuav zoo li nyuaj me ntsis rau kev nkag siab, cia peb nkag siab nrog ib qho piv txwv yooj yim.
Xav txog cov leeg nqaij hauv peb lub plawv zoo li ib pawg twj dej me me. Cov twj no xav tau lub zog kom ua haujlwm tau zoo. Lub zog no los ntawm cov zaub mov hu ua calcium .
Cov glycosides hauv lub plawv ua haujlwm los ntawm kev khaws cia me ntsis ntawm cov sodium ions hauv cov hlwb plawv. Thaum cov sodium hauv cov hlwb nce ntxiv, cov calcium hauv cov hlwb kuj nce ntxiv.
Thaum muaj calcium ntau ntxiv, cov leeg nqaij ntawm lub plawv yuav nruj dua . Qhov no txhais tau tias cov ntshav uas raug nqus mus rau hauv lub cev nrog txhua zaus dhia yuav nce ntxiv. Hauv kev kho mob, peb hu qhov no ua kev nce ntxiv ntawm cov zis ntawm lub plawv . Qhov no tseem ceeb heev rau ib tus neeg uas muaj teeb meem plawv tsis ua haujlwm.
Tsis tas li ntawd xwb, cov tshuaj no ua lwm yam.
Lub plawv dhia ceev yog tswj los ntawm ib lub tshuab hluav taws xob. Cov tshuaj no ua haujlwm los ntawm kev ua kom qeeb qeeb ntawm qhov ceev uas cov teeb liab hluav taws xob mus, tshwj xeeb tshaj yog thaum lawv hla dhau AV node hauv lub plawv. Qhov no ua rau lub plawv dhia qeeb. Qhov no tuaj yeem pab tau zoo rau cov neeg uas muaj mob xws li atrial fibrillation, uas ua rau lub plawv dhia ceev tsis zoo.
Cov tshuaj no yog sau rau leej twg?
Qhov no yog ib qho tseem ceeb heev. Yav dhau los, cov tshuaj no tau siv dav rau kab mob plawv. Tab sis tam sim no tsis yog li ntawd .
Tam sim no, cov tshuaj 'Cardiac Glycosides' tsis yog cov tshuaj thawj zaug. Yog li ntawd, lawv tsis yog cov tshuaj xaiv thawj zaug ntawm tus kws kho mob rau kev mob plawv nres lossis kev mob plawv dhia tsis xwm yeem.
Feem ntau, tus kws kho mob yuav xub sau cov tshuaj no rau:
- Cov tshuaj beta-blockers
- Cov tshuaj ACE inhibitors
- Cov tshuaj diuretics - Qhov no yog qhov peb hu ua "tshuaj dej".
- Cov tshuaj ARBs (Angiotensin II Receptor Blockers)
Vim li cas cov tshuaj no thiaj raug muab ua ntej yog vim lawv muaj kev nyab xeeb dua li cov glycosides hauv lub plawv thiab muaj tsawg dua cov kev mob tshwm sim loj.
Yog li, leej twg tau txais 'Cardiac Glycosides'?
Rau qee tus neeg mob uas cov tshuaj uas tau hais ua ntej tsis tswj tau cov tsos mob zoo, tus kws kho mob yuav sau ntawv kom muab cov tshuaj no rau. Qhov ntawd yog, tsuas yog tias cov txiaj ntsig rau tus neeg mob ntau dua li cov kev pheej hmoo.
Cov kev pheej hmoo thiab cov kev mob tshwm sim yog dab tsi?
Ib yam li lwm yam tshuaj, cov tshuaj no tuaj yeem ua rau muaj kev phiv. Tab sis peb yuav tsum ceev faj ntxiv me ntsis nrog cov tshuaj no. Qhov laj thawj yog vim tsis muaj qhov sib txawv loj ntawm cov tshuaj uas yog kho thiab cov tshuaj lom uas ua rau muaj kev phiv.
Hais yooj yim xwb, yog koj nce qhov koob tshuaj me ntsis xwb los, qhov muaj feem yuav muaj kev phiv ntxiv yuav nce ntxiv. Yog li ntawd , tsis txhob hloov qhov koob tshuaj ntawm koj cov tshuaj yam tsis tau sab laj nrog koj tus kws kho mob .
Cia peb saib cov teeb meem uas cov tshuaj no tuaj yeem tshwm sim hauv ib lub rooj.
| Teeb meem | Cov yam ntxwv |
|---|---|
| Cov kev mob tshwm sim feem ntau (feem ntau tsis loj heev) |
|
| Cov tsos mob ntawm kev lom tshuaj (Toxicity) ( Nrhiav kev pab kho mob tam sim ntawd! ) |
|
Vim tias cov tshuaj no nyob hauv lub cev ib ntus, nws tuaj yeem sib sau ua ke raws sijhawm. Yog vim li ntawd koj tus kws kho mob yuav kuaj xyuas koj cov ntshav thiab kuaj xyuas koj cov digoxin.
Thaum twg kuv yuav tsum mus ntsib kws kho mob tam sim ntawd?
Yog tias koj noj cov tshuaj no thiab muaj cov tsos mob hauv qab no, mus ntsib koj tus kws kho mob yam tsis muaj kev ncua.
- Yog tias koj ua pa nyuaj
- Yog tias koj txhais tes lossis ko taw pib o
- Yog tias mob plab, raws plab, lossis ntuav tseem muaj
- Yog tias koj poob tag nrho lub siab xav noj mov
Yog tias cov tsos mob ntawm kev lom tshwm sim, nws yog ib qho tseem ceeb uas yuav tsum mus rau chav kho mob ceev (ETU) ntawm tsev kho mob tam sim ntawd. Yog tias koj xav tau cov ntaub ntawv ntxiv, koj tuaj yeem hu rau Lub Chaw Qhia Txog Kev Lom Zem Hauv Tebchaws ntawm Tsev Kho Mob Colombo National kom tau txais lus qhia.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Cov tshuaj glycosides hauv lub plawv (piv txwv li Digoxin) yog cov tshuaj uas pab lub plawv tsis muaj zog tso ntshav tau zoo dua thiab tswj lub plawv dhia ceev.
- Niaj hnub nim no, nws tsis yog siv ua thawj kab tshuaj vim nws muaj kev pheej hmoo thiab cov kev mob tshwm sim.
- Qhov koob tshuaj uas koj tau muab rau koj yog ib qho tseem ceeb heev. Tsis txhob hloov qhov koob tshuaj rau txhua yam laj thawj yam tsis tau sab laj nrog koj tus kws kho mob.
- Kev lom yog qhov txaus ntshai tiag tiag. Saib xyuas cov tsos mob xws li kev hloov pauv ntawm qhov muag (qhov muag daj/ntsuab), qaug zog heev, lossis mob plab. Yog tias qhov no tshwm sim, nrhiav kev pab kho mob tam sim ntawd.
- Txawm koj xav tias koj zoo li cas los xij, nws yog ib qho tseem ceeb heev uas yuav tsum noj koj cov tshuaj rau lub sijhawm uas tau teem tseg thiab mus rau cov chaw kho mob raws li hnub teem tseg raws li koj tus kws kho mob tau hais.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus