Koj puas xav tias koj tsis muaj zog? Koj ob txhais ceg puas tingling? Cia peb kawm txog CIDP (Chronic Inflammatory Demyelinating Polyneuropathy)!

Puas muaj tej lub sij hawm koj xav tias koj nkees heev, koj txhais tes thiab ceg tsis muaj zog, lossis koj muaj qhov mob tingling? Tej lub sij hawm koj yuav tsis tau ua tib zoo saib xyuas tej yam no. Txawm li cas los xij, qee zaum, cov tsos mob no tuaj yeem yog ib qho cim qhia txog qee yam loj dua. Ib qho mob uas tsis tshua muaj tab sis tseem ceeb uas yuav tsum paub txog yog hu ua CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) . Txawm hais tias lub npe yuav zoo li ntev me ntsis, cia peb ua kom yooj yim.

CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) yog dab tsi?

Txawm hais tias lub npe no yuav zoo li nyuaj me ntsis, yog tias peb rhuav tshem nws lub ntsiab lus, peb tuaj yeem tau txais lub tswv yim zoo dua ntawm tus kab mob no.

• Mob ntev: Qhov no txhais tau tias "mob ntev." Qhov no txhais tau tias CIDP tsis tshwm sim sai sai thiab zoo dua sai. Nws tshwm sim qeeb qeeb, tsawg kawg yog yim lub lis piam. Qee zaum cov tsos mob ploj mus thiab tom qab ntawd rov tshwm sim ntau lub hlis lossis txawm tias ntau xyoo tom qab. Nws zoo li teeb meem rov tshwm sim.

• Mob o: Qhov no txhais tau tias "mob o" . Thaum peb raug mob qhov twg ntawm peb lub cev, nws o thiab ua liab, puas yog? Nws yog li ntawd. Tab sis hauv CIDP, qhov mob o no tshwm sim vim muaj teeb meem hauv peb lub cev tiv thaiv kab mob . Hais yooj yim, cov tub rog uas yuav tsum tiv thaiv peb lub cev pib tawm tsam peb cov hlab ntsha los ntawm kev ua yuam kev. Qhov no hu ua "Kev Tawm Tsam Autoimmune" . Qhov mob o ntau dhau los ntawm qhov no ua rau peb cov hlab ntsha peripheral puas tsuaj. Cov hlab ntsha peripheral no yog cov hlab ntsha uas txuas ntxiv los ntawm lub hlwb thiab tus txha caj qaum.

• Kev Tshem Tawm Myelinating: Lo lus no yog ib lo lus tob me ntsis. Peb cov neurons muaj ib daim ntaub thaiv ib puag ncig lawv. Nws zoo li ib lub hnab yas nyob ib puag ncig ib txoj hlua hluav taws xob. Daim ntaub thaiv no hu ua '(Myelin Sheath)' . Daim ntaub thaiv myelin no yog qhov uas tso cai rau cov lus ntawm cov hlab ntsha mus ncig sai thiab raug. '(Demyelinating)' txhais tau tias daim ntaub thaiv myelin raug rhuav tshem lossis puas lawm. Tom qab ntawd, ib yam li thaum cov yas ntawm cov hlau raug tshem tawm, cov hluav taws xob ntws tawm, thiab cov lus ntawm cov hlab ntsha tsis mus ncig zoo.

• Polyneuropathy: "Poly" txhais tau tias "ntau." "Neuropathy" txhais tau tias kev puas tsuaj rau cov hlab ntsha. Polyneuropathy txhais tau tias kev puas tsuaj rau ntau cov hlab ntsha hauv lub cev tib lub sijhawm. Qhov no tuaj yeem ua rau muaj ntau yam teeb meem xws li cov leeg tsis muaj zog, loog, thiab paresthesia.

Yog li, hais yooj yim xwb, CIDP yog ib qho mob ntev uas lub myelin sheath nyob ib puag ncig cov hlab ntsha peripheral raug puas tsuaj vim yog qhov ua haujlwm tsis zoo hauv peb lub cev tiv thaiv kab mob, ua rau muaj kev ua haujlwm tsis zoo ntawm ntau cov hlab ntsha. Koj puas nkag siab?

Qhov txawv ntawm Guillain-Barré Syndrome (GBS) thiab CIDP yog dab tsi?

Tej zaum kojTej zaum koj twb tau hnov ​​txog '(Guillain-Barré Syndrome)' lossis '(GBS) .' Tus kab mob CIDP zoo ib yam li GBS. Cov kws kho mob xav tias CIDP yog ib hom kab mob GBS uas kis mus ntev. GBS kuj yog ib hom kab mob tsis tshua muaj uas peb lub cev tiv thaiv kab mob tawm tsam cov hlab ntsha peripheral.

Tiam sis qhov txawv tseem ceeb yog lub sijhawm. Qhov phem tshaj plaws ntawm GBS feem ntau tuaj txog ob mus rau peb lub lis piam tom qab cov tsos mob pib. Tab sis feem ntau cov neeg maj mam zoo dua tom qab ntawd. Tab sis CIDP kav ntev dua. Cov tsos mob maj mam zuj zus tsawg kawg yog yim lub lis piam .

CIDP muaj pes tsawg zaus?

CIDP yog ib qho mob tsis tshua muaj . Raws li cov kws tshawb fawb, tus lej ntawm cov neeg mob CIDP tshiab hauv Tebchaws Meskas yog ntawm 0.8 thiab 8.9 rau txhua 100,000 tus neeg hauv ib xyoos. Qhov ntau no loj me ntsis, vim CIDP tuaj yeem cuam tshuam rau ntau tus neeg sib txawv hauv ntau txoj kev, thiab vim tias tus kab mob nyuaj rau kuaj mob.

CIDP tuaj yeem tshwm sim thaum twg los tau.

Cov tsos mob ntawm CIDP yog dab tsi?

Cov tsos mob ntawm CIDP tuaj yeem sib txawv nyob ntawm hom. Txawm li cas los xij, cov tsos mob feem ntau yog cov leeg tsis muaj zog zuj zus uas kav ntev li yim lub lis piam. Qhov no feem ntau cuam tshuam rau ob sab ntawm lub cev sib npaug. Tshwj xeeb:

• Cov leeg ntawm thaj tsam ntawm lub duav thiab lub duav
• Cov leeg ntawm lub xub pwg nyom thiab thaj tsam sab caj npab sab saud
• Xibtes thiab ntiv tes
• Taw thiab ntiv taw

Xav txog seb, koj mam li pom tias nws nyuaj rau sawv ntawm lub rooj zaum, xav tias koj tsis tuaj yeem nce ntaiv, lossis pom tias nws nyuaj rau txhuam koj cov plaub hau lossis tuav ib khob. Tej yam zoo li no tuaj yeem tshwm sim.

Lwm cov tsos mob uas yuav pom muaj xws li:

• Atrophy ntawm cov leeg nqaij cuam tshuam
• Kev tsis muaj zog, tingling, lossis poob ntawm kev hnov ​​​​​​ntawm cov ntiv tes thiab cov ntiv taw (Paresthesia)
• Nyuaj siab tswj lub cev kom sib npaug thiab tsis sib koom tes zoo (xws li kev ntog)
• Kev nyuaj siab taug kev lossis poob kev taug kev tag nrho
• Poob los yog tsis muaj zog ntawm cov leeg nqaij tob tob (qhov no yog qhov uas tus kws kho mob yuav kuaj los ntawm kev siv lub rauj me me los kov lub hauv caug)
• Mob Neuropathic. Qhov no yog qhov mob uas zoo li kub hnyiab lossis raug hluav taws xob tsoo.

Tsis tshua muaj, koj kuj yuav pom cov tsos mob zoo li:

• Nyuaj nqos (Dysphagia) thiab qaug zog ntawm lub caj dab sab saud
• Pom Kev Ob Zaug

Cov tsos mob no yuav hloov pauv raws sijhawm. Tej zaum lawv yuav pib qeeb qeeb, lossis lawv yuav nce mus sai sai. Qee zaum lawv yuav tuaj thiab ploj mus, ploj mus tom qab ob peb hnub, thiab tom qab ntawd rov qab los. Yog tias koj muaj cov tsos mob no, nws yog ib qho tseem ceeb uas yuav tsum mus ntsib kws kho mob sai li sai tau.Kev kuaj mob thiab kev kho mob thaum ntxov yuav pab tau koj kom zoo sai sai.

Puas muaj ntau hom CIDP sib txawv?

Yog, muaj ntau hom CIDP sib txawv, thiab lawv cov tsos mob txawv me ntsis.

Hom mob CIDP uas pom ntau tshaj plaws yog hom mob CIDP ib txwm muaj , uas ua rau cov leeg tsis muaj zog thiab cov tsos mob ntawm kev hnov ​​​​​​lus (xws li loog) ntawm ob sab ntawm lub cev.

Qee cov kev hloov pauv atypical yog:

• `(Multifocal Motor Neuropathy)`: Qhov no tsuas yog cuam tshuam txog cov leeg nqaij tsis muaj zog xwb. Qhov tsis muaj zog no kuj tsis sib npaug, txhais tau tias nws tsuas yog cuam tshuam rau ib qho chaw ntawm ib sab ntawm lub cev, lossis ntau qhov chaw hauv ntau txoj kev sib txawv.
• ` (Lewis-Sumner Syndrome): Qhov no cuam tshuam txog ob qho tib si cov leeg nqaij tsis muaj zog thiab cov tsos mob ntawm kev hnov.
• `(Pure Sensory CIDP)`: Qhov no tuaj yeem ua rau loog, mob, teeb meem sib npaug, thiab kev taug kev tsis zoo. Tab sis tsis muaj leeg nqaij qaug zog.
• `(Pure Motor CIDP):`: Hauv qhov no, cov leeg nqaij tsis muaj zog thiab poob ntawm cov reflexes cuam tshuam rau ob sab ntawm lub cev tuaj yeem pom, tab sis tsis muaj cov tsos mob ntawm kev hnov.

Cov kws tshawb nrhiav tseem tab tom kawm txog lwm yam kev hloov pauv ntawm CIDP.

Dab tsi ua rau CIDP?

Raws li peb tau tham ua ntej lawm, cov kws tshawb fawb ntseeg tias CIDP yog tshwm sim los ntawm kev ua haujlwm tsis zoo hauv peb lub cev tiv thaiv kab mob . Txawm hais tias qhov ua rau muaj tseeb tseem tsis tau paub, peb lub cev tiv thaiv kab mob pom lub myelin sheath ua tus yeeb ncuab thiab tom qab ntawd pib tawm tsam nws (kev tiv thaiv kab mob autoimmune).

Lub plhaub myelin yog txheej tiv thaiv ib puag ncig peb cov hlwb paj hlwb. Nws qhwv ib ncig ntawm qhov ntev ntawm cov hlwb paj hlwb (axon). Myelin yog qhov uas tso cai rau cov hluav taws xob mus ncig raws cov hlab ntsha kom raug. Thaum myelin puas lawm, cov hluav taws xob no mus qeeb heev, lossis ploj tag nrho. Tom qab ntawd cov "lus" tsis mus txog qhov chaw uas lawv yuav tsum mus. Qhov ntawd yog qhov ua rau muaj cov tsos mob ntawm CIDP.

Xav txog ib txoj hlua hluav taws xob uas muaj rwb thaiv tsev zoo. Nws xa hluav taws xob tau zoo heev. Tab sis yuav ua li cas yog tias lub hnab yas ntawm txoj hlua ntawd tawm qee qhov? Cov hluav taws xob xau, lossis tsis ntws zoo, puas yog? Qhov ntawd yog qhov tshwm sim thaum lub hnab myelin puas lawm.

Yuav kuaj mob CIDP li cas?

Kev kuaj mob CIDP yuav nyuaj vim tias ntau hom muaj cov tsos mob sib txawv. Yuav kom kuaj mob CIDP, koj tus kws kho mob yuav:

• Lawv yuav mloog koj cov tsos mob kom zoo zoo thiab nug txog koj keeb kwm kev kho mob .
• Yuav kuaj lub cev thiab kuaj lub paj hlwb .
• Tej zaum yuav muaj ntau qhov kev kuaj tshwj xeeb los xyuas kom meej tias muaj tus kab mob lossis tshem tawm lwm yam mob.

Cov kev kuaj twg siv los kuaj mob CIDP?

Cov no yog cov kev kuaj mob uas tuaj yeem pab paub tseeb tias CIDP thiab tshem tawm lwm yam ua rau:

• Kev Ntsuas Hluav Taws Xob (EMG) thiab Kev Ntsuas Kev Sib Txuas Lus ntawm Cov Nerve: Cov kev ntsuam xyuas no saib xyuas kev noj qab haus huv thiab kev ua haujlwm ntawm koj cov leeg thiab cov hlab ntsha uas tswj lawv. Cov kev ntsuam xyuas no yog qhov tshwj xeeb tshaj yog rau kev nrhiav kev hloov pauv demyelinating (kev xa qeeb ntawm cov cim hlab ntsha, kev thaiv, thiab lwm yam) zoo li CIDP. Qhov no tuaj yeem pab cais CIDP ntawm lwm hom polyneuropathies.

• Kev Ntsuas Pob Txha / Kev Ntsuas Lumbar: Hauv qhov kev kuaj no, tus kws kho mob yuav muab ib rab koob me me ntxig rau hauv koj lub nraub qaum qis thiab coj ib qho qauv ntawm koj cov kua dej cerebrospinal (CSF) . Cov qauv no raug xa mus rau chav kuaj mob kom kuaj. Hauv 85% txog 90% ntawm cov neeg uas muaj CIDP, cov qe ntshav dawb yog qhov ib txwm muaj, tab sis cov protein theem siab dua. Lwm yam kev tsis zoo hauv CSF yuav qhia txog lwm yam mob.

• Kev Ntsuas Duab Sib Nqus (MRI) ntawm sab nraub qaum qis: Yog tias cov hauv paus hlab ntsha hauv koj sab nraub qaum qis nqus cov xim sib piv thaum lub sijhawm MRI scan, nws tuaj yeem pab kuaj mob CIDP.

• Kev Kuaj Ntshav: Koj tus kws kho mob yuav hais kom kuaj ntshav kom paub seb puas muaj lwm yam mob uas ua rau mob neuropathy, xws li ntshav qab zib, tsis muaj vitamin txaus, mob thyroid, mob Lyme, HIV/AIDS, thiab lymphoma. Lawv kuj tseem yuav kuaj xyuas qee yam tshuaj tiv thaiv kab mob uas pom tias muaj feem cuam tshuam nrog CIDP.

• Kev Kuaj Mob Hlwb: Tsis tshua muaj, tus kws kho mob yuav pom zoo kom kuaj mob hlwb, uas yuav tsum tshem tawm ib daim hlab ntsha thiab kuaj xyuas seb puas muaj kev puas tsuaj rau myelin sheath.

Cov kev kho mob rau CIDP yog dab tsi?

Muaj peb txoj kev kho mob tseem ceeb (thawj kab) rau CIDP:

• Corticosteroids: Cov tshuaj steroid, xws li prednisolone, pab txo qhov o. Rau ntau tus neeg, cov tshuaj steroids no ib leeg tuaj yeem pab txo cov tsos mob. Txawm li cas los xij, cov tshuaj steroids tuaj yeem muaj cov kev mob tshwm sim loj heev, yog li kev siv cov tshuaj no mus sij hawm ntev yog txwv. Koj tus kws kho mob kuj tseem yuav sau ntawv rau lwm cov tshuaj (cov tshuaj tiv thaiv kab mob) nrog rau cov tshuaj steroids.

• Kev Hloov Plasma / Plasmapheresis: Hauv kev kho mob no, lub tshuab cais cov plasma ntawm koj cov ntshav, kho nws, thiab tom qab ntawd xa cov plasma thiab cov ntshav rov qab rau koj lub cev. Hais yooj yim, nws lim cov tshuaj tua kab mob hauv cov plasma uas tawm tsam koj cov hlab ntsha. Kev hloov Plasma feem ntau tsuas yog ua haujlwm rau ob peb lub lis piam xwb. Tej zaum koj yuav tsum tau kho qhov no rau ntau lub hlis, lossis txawm tias ntau xyoo.

• Kev Kho Mob Immunoglobulin Hauv Kab Mob (IVIG): Hauv kev kho mob no, cov protein hu ua immunoglobulins (cov protein uas peb lub cev tiv thaiv kab mob ua rau tawm tsam cov neeg nkag teb chaws) raug muab rau hauv kab mob (IV). Cov immunoglobulin no tau txais los ntawm cov ntshav ntawm ntau txhiab tus neeg noj qab haus huv. IVIG tuaj yeem txo qhov kev puas tsuaj uas koj lub cev tiv thaiv kab mob ua rau koj cov hlab ntsha. IVIG yuav raug muab rau hauv cov koob tshuaj ntau heev thaum xub thawj, thiab koj yuav tsum tau txais kev kho mob no tsis tu ncua rau ntau lub hlis, lossis txawm tias ntau xyoo.

Cov kws tshawb nrhiav tam sim no tab tom kawm txog lwm yam kev kho mob rau CIDP. Tej zaum koj kuj yuav muaj lub sijhawm los koom nrog kev sim tshuaj rau CIDP. Tham nrog koj tus kws kho mob txog qhov no.

Lub neej zoo li cas nrog CIDP? (Kev kwv yees)

Qhov kev xav mus sij hawm ntev ntawm tus kab mob nyob ntawm ntau yam tseem ceeb:

• Koj muaj hnub nyoog thaum CIDP pib.
• Tus kab mob no loj hlob li cas thiab hom kab mob li cas .
• kuaj pom tus kab mob sai npaum li cas thiab pib kho mob .
• Koj lub cev teb li cas rau kev kho mob thaum xub thawj .

Kwv yees li 90% ntawm cov neeg uas muaj CIDP tuaj yeem kho tau los ntawm kev kho mob. Tab sis kwv yees li 50% ntawm cov neeg rov qab mob dua. Feem ntau, qhov kev kwv yees mus sij hawm ntev ntawm cov neeg uas kuaj pom tias muaj CIDP thaum tseem hluas yog qhov zoo. Yog tias koj tsis tau txais kev kho mob rau CIDP, kev puas tsuaj rau cov hlab ntsha mus tas li tuaj yeem tshwm sim, uas tuaj yeem ua rau muaj qee qhov kev tsis taus.

Koj tus kws kho mob yuav muab tau ib lub tswv yim zoo rau koj txog yam uas yuav tshwm sim tom ntej raws li koj tus mob tshwj xeeb.

CIDP puas ua rau lub neej luv dua?

CIDP tsis yog ib yam kab mob uas ua rau tuag taus. Cov neeg uas muaj tus kab mob no feem ntau muaj lub neej ntev ib yam li cov neeg uas tsis muaj tus kab mob no. Yog li ntawd, tsis muaj dab tsi yuav tsum txhawj txog.

Puas tiv thaiv tau CIDP?

Vim tias cov kws tshawb nrhiav tseem tsis tau pom ib qho laj thawj tshwj xeeb rau CIDP, tam sim no tsis muaj txoj hauv kev paub los tiv thaiv tus kab mob kom tsis txhob loj hlob.

Thaum twg kuv yuav tsum mus ntsib kws kho mob? / Thaum twg kuv yuav tsum mus rau chav kho mob ceev?

Yog tias koj tau kuaj pom tias muaj CIDP, koj yuav tsum mus ntsib koj tus kws kho mob tsis tu ncua kom saib xyuas koj cov tsos mob thiab tau txais kev kho mob. Cov tsos mob CIDP tuaj yeem tshwm sim thiab ploj mus rau ntau lub hlis lossis txawm tias ntau xyoo, yog li kev kho mob txuas ntxiv mus yuav tsim nyog.

Tsis tshua muaj, CIDP tuaj yeem cuam tshuam rau cov leeg nqaij uas xav tau los ua pa . Yog tias koj muaj teeb meem ua pa , hu rau 911 (lossis koj tus xov tooj xwm txheej ceev hauv zos) tam sim ntawd, lossis mus rau chav kho mob xwm txheej ceev ze tshaj plaws. Qhov no yog xwm txheej ceev.

Thaum kawg, tej yam uas yuav tsum nco ntsoov

Nws yuav ua rau ntshai heev yog tias koj xav tias koj tswj tsis tau koj lub cev. Tab sis qhov xov xwm zoo yog tias cov tsos mob ntawm CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) tuaj yeem kho tau, tshwj xeeb tshaj yog tias koj pib kho thaum ntxov. Nco ntsoov tias koj pab neeg kho mob nrog koj txhua kauj ruam ntawm txoj kev los daws qhov teeb meem no. Yog li ua siab loj thiab ua raws li koj tus kws kho mob cov lus qhia.

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