Koj puas tau xav txog seb lub cev ua haujlwm zoo kawg nkaus li cas hauv peb lub cev los tiv thaiv peb ntawm cov kab mob? Ib yam li ib pab tub rog uas tiv thaiv lub tebchaws, peb lub cev kuj muaj lub cev tiv thaiv kab mob hu ua Lub Cev Tiv Thaiv Kab Mob. Lub cev no muaj ntau hom hlwb sib txawv uas zoo li cov tub rog. Tab sis muaj lwm qhov uas pab cov tub rog tseem ceeb no, zoo li ib pab tub rog tshwj xeeb uas ceev heev. Qhov ntawd yog qhov peb hu ua Lub Cev Sib Koom Tes. Niaj hnub no peb tab tom tham txog lub zog zais cia no.
Hauv lus yooj yim, qhov Complement System yog dab tsi?
Lub Txheej Txheem Sib Pab yog ib feem ntawm peb lub cev tiv thaiv kab mob. Nws hu ua "Complement" vim nws ua lub luag haujlwm tseem ceeb heev hauv "kev sib pab" lossis "pab" txoj haujlwm ntawm lwm cov hlwb hauv peb lub cev tiv thaiv kab mob. Xav txog nws zoo li koj tus phooj ywg zoo tshaj plaws, ib txwm nyob ntawd los txhawb koj.
Hais yooj yim xwb, qhov no yog thawj kab tiv thaiv hauv peb lub cev txoj kev tiv thaiv. Nws yog qhov uas ua kom lub cev ua haujlwm thiab ceeb toom sai li sai tau thaum tus yeeb ncuab, xws li kab mob lossis kab mob me me, nkag mus rau hauv lub cev. Tsis tas li ntawd, nws txoj haujlwm tseem ceeb yog tshem tawm cov hlwb raug mob tom qab muaj xwm txheej thiab pab kho cov chaw ntawd.
Cov haujlwm tseem ceeb ntawm lub kaw lus no yog dab tsi?
Lub cev no yuav ua haujlwm thaum nws pom ib tug yeeb ncuab sab nraud (piv txwv li, ib tug kab mob). Tom qab ntawd, ntawm no yog cov yam tseem ceeb uas tshwm sim:
- Kev Taw Qhia Cov Yeeb Ncuab: Lawv nrhiav cov tshuaj lom neeg, xws li cov kab mob me me, uas tau nkag mus rau hauv lub cev, txuas rau lawv, thiab qhia rau lwm cov hlwb hauv lub cev tiv thaiv kab mob, "Qhov no yog yeeb ncuab." Nws zoo li pleev xim rau lub cev ntawm tus yeeb ncuab kom yooj yim dua rau lwm tus paub.
- Ua rau o: Thaum koj raug mob, thaj chaw ntawd yuav liab, o, thiab kub, puas yog? Qhov ntawd yog qhov o. Qhov no yog ib qho zoo. Nws ua rau muaj ntshav ntau ntxiv rau thaj chaw ntawd, coj cov qe ntshav dawb ntau ntxiv los tawm tsam cov kab mob. Kev pab pib cov txheej txheem no yog ib qho tseem ceeb ntawm Complement System.
- Tshem Tawm Cov Yeeb Ncuab: Thaum cov yeeb ncuab raug txheeb xyuas lawm, lub kaw lus no ua rau lawv puas tsuaj. Qee zaum cov protein no sib xyaw ua qhov rau ntawm phab ntsa ntawm cov kab mob bacterial, ua rau nws puas tsuaj. Lawv kuj pab tshem tawm cov khoom me me ntawm cov yeeb ncuab uas raug rhuav tshem thiab cov cell tuag ntawm qhov ntawd.
Lub tshuab no ua los ntawm dab tsi? Nws ua haujlwm li cas?
Lub cev zoo kawg no yog ua los ntawm cov protein. Nws muaj li ntawm 50 hom protein uas ntab hauv cov kua ntawm peb cov ntshav hu ua plasma, thiab me me heev uas tsuas pom tau nrog lub tshuab microscope xwb. Peb hu cov plasma protein no ua plasma protein .
Cov protein no yog tsim nyob rau hauv peb lub siab. Tom qab ntawd lawv sib sau ua ke hauv cov ntshav thiab lwm cov nqaij ntawm lub cev, npaj txhij rau kev ua haujlwm txhua lub sijhawm.
Tiam sis qhov xav tsis thoob yog, feem ntau cov protein no nyob rau hauv lub xeev "tsis ua haujlwm" . Zoo li lawv tsaug zog. Lawv tsis yog ua lawv txoj haujlwm xwb. Lawv tsuas yog sawv thaum lub cev raug mob lossis thaum tus yeeb ncuab, zoo li tus kab mob, nkag mus.
Cascade
Txoj kev uas cov protein no sawv los zoo kawg nkaus li. Zoo li ib kab ntawm cov dominoes poob.
Xav txog koj muaj ib kab ntawm cov dominoes. Yuav ua li cas thaum koj kov thawj domino nrog koj tus ntiv tes? Nws poob thiab tsaws rau ntawm domino tom ntej. Qhov ntawd ua rau domino tom ntej poob. Thiab ua li ntawd mus txog thaum koj mus txog domino kawg, puas yog?
Cov protein hauv lub kaw lus sib txuas ua haujlwm tib yam. Ib qho ua rau cov protein thawj zaug ua haujlwm. Tom qab ntawd nws ua rau cov protein tom ntej ua haujlwm. Thiab tom qab ntawd cov protein tom ntej ... thiab lwm yam, ua rau muaj kev sib txuas lus. Hauv kev kho mob, peb hu qhov no ua "cascade." Thaum txhua cov protein raug ua haujlwm, txhua tus ua nws txoj haujlwm tiv thaiv thiab xa cov lus mus rau qhov tom ntej.
Yog tias muaj teeb meem nrog lub cev complement system, yuav muaj kab mob dab tsi tshwm sim?
Lub cev no tseem ceeb heev rau peb lub cev uas tej yam tsis muaj zog lossis ua haujlwm ntau dhau hauv nws tuaj yeem ua rau muaj teeb meem loj rau kev noj qab haus huv. Muaj ob hom teeb meem tseem ceeb ntawm no:
1. Tsis txaus lub cev sib txuas: Qhov no txhais tau tias cov protein hauv lub cev no tsis txaus, lossis lawv tsis ua haujlwm zoo. Thaum lub sijhawm zoo li no, peb lub cev tiv thaiv kab mob tsis muaj zog. Tom qab ntawd, qhov muaj feem yuav kis tau kab mob ntau zaus, tshwj xeeb tshaj yog cov kab mob bacterial, muaj ntau dua. Qee zaum, cov kab mob no tuaj yeem hnyav thiab ua rau muaj mob hnyav xws li sepsis .
2. Kev ua haujlwm ntau dhau ntawm lub cev sib txuas: Qhov no txhais tau tias lub cev no ua haujlwm ntau dua li nws yuav tsum tau ua. Nws raug ua haujlwm ntau zaus yam tsis muaj laj thawj. Thaum qhov no tshwm sim, lub cev no pib tawm tsam tsis yog cov yeeb ncuab uas tau nkag mus rau hauv lub cev xwb, tab sis kuj tawm tsam nws cov hlwb noj qab haus huv. Peb hu qhov no ua cov kab mob autoimmune .
Hais yooj yim xwb, lub kaw lus no zoo li tus neeg saib xyuas kev ruaj ntseg. Yog tias tus neeg saib xyuas kev ruaj ntseg tsaug zog, cov tub sab tuaj yeem nkag mus hauv tsev tau yooj yim (qhov tsis zoo). Yog tias tus neeg saib xyuas kev ruaj ntseg ntxhov siab dhau thiab pib tawm tsam cov tswv cuab hauv tsev neeg, qhov ntawd kuj yog teeb meem (ua haujlwm ntau dhau).
| Mob nkeeg | Kev Sib Raug Zoo Nrog Lub Txheej Txheem Sib Txuas |
|---|---|
| Mob ntsws ua xua | Kev ua haujlwm ntau dhau ntawm lub cev tuaj yeem ua rau mob o ntawm txoj hlab pa. |
| Kab mob ntshav tsis txaus | Hauv qee hom, lub kaw lus no pab txhawb rau kev puas tsuaj ntawm cov qe ntshav liab. |
| Mob qog noj ntshav - piv txwv li mob leukemia, lymphoma | Qee cov qog nqaij hlav siv cov txheej txheem los zam txoj kab ke no, thiab qee qhov kev kho mob tsom mus rau txoj kab ke no. |
| Kab mob raum | Kev ua haujlwm ntau dhau ntawm lub cev tuaj yeem ua rau lub raum puas tsuaj. |
| Kev puas tsuaj ntawm cov hlab ntsha hauv lub cev | Tus kab mob no, uas ua rau lub retina ntawm lub qhov muag puas tsuaj, kuj muaj feem cuam tshuam nrog kev ua haujlwm ntawm lub cev complement. |
| Mob pob qij txha caj qaum | Qhov no yog ib qho kab mob autoimmune, thiab lub cev sib txuas ua rau muaj kev puas tsuaj rau cov pob qij txha. |
Cov tsos mob ntawm hom teeb meem no yuav yog dab tsi?
Yog tias lub cev tiv thaiv kab mob tsis ua haujlwm zoo, koj lub cev tiv thaiv kab mob yuav tsis muaj zog, thiab koj yuav muaj cov tsos mob zoo li no.
| Cov tsos mob | Kev piav qhia |
|---|---|
| Kev kis kab mob ntau zaus | Vim tsis muaj zog tiv thaiv kab mob, cov kab mob xws li mob khaub thuas, mob ntsws, thiab mob ntsws tuaj yeem tshwm sim ntau zaus. |
| Kev qaug zog thiab kev qaug zog tas li | Tej zaum koj yuav xav tias nkees heev vim muaj kev sib ntaus sib tua tas li hauv koj lub cev lossis vim koj lub cev tsis ua haujlwm zoo. |
| Mob pob qij txha | Cov pob qij txha o thiab mob tuaj yeem tshwm sim, tshwj xeeb tshaj yog nyob rau hauv cov kab mob autoimmune. |
| Kev o (mob) | Ntau qhov ntawm lub cev, tshwj xeeb yog cov pob qij txha thiab daim tawv nqaij, tuaj yeem o. |
Yog tias koj muaj cov tsos mob no, tshwj xeeb tshaj yog tias koj ntsib lawv tas li , tsis txhob txhawj txog nws thiab mus ntsib koj tus kws kho mob .
Yuav ua li cas thiaj kuaj xyuas tau qhov kev noj qab haus huv ntawm lub tshuab no?
Yog tias tus kws kho mob xav tias qhov system no raws li koj cov tsos mob, lawv tuaj yeem ua ntau qhov kev kuaj kom paub meej.
Qhov kev kuaj ntshav tseem ceeb tshaj plaws yog kev kuaj ntshav hu ua kev kuaj complement . Qhov no suav nrog kev coj ib qho qauv ntshav me me los ntawm cov leeg ntshav hauv koj txhais caj npab thiab ntsuas qhov ntau ntawm cov protein complement hauv nws thiab lawv ua haujlwm zoo li cas.
Cov kev kuaj no tuaj yeem pab koj tus kws kho mob nrhiav tau tej yam xws li:
- Vim li cas koj thiaj kis tau kab mob ntau zaus?
- Dab tsi ua rau koj tus kab mob autoimmune thiab nws cov kev kho mob zoo npaum li cas?
- Koj lub cev tiv thaiv kab mob zoo li cas lawm?
Tsis tas li ntawd xwb, tej zaum yuav muaj lwm yam kev kuaj mob, xws li suav cov ntshav tag nrho thiab cov qib immunoglobulin.
Koj ua dab tsi li kev kho mob?
Kev kho mob nyob ntawm seb koj muaj teeb meem dab tsi, txawm tias nws yog qhov tsis txaus lossis kev ua haujlwm ntau dhau ntawm lub cev. Lub hom phiaj tseem ceeb ntawm kev kho mob yog los tswj cov tsos mob thiab ua kom lub cev ua haujlwm tau zoo.
- Cov Tshuaj Tua Kab Mob: Cov tshuaj tua kab mob yog muab los kho thiab tiv thaiv cov kab mob bacterial uas tshwm sim ntau zaus vim yog lub cev tiv thaiv kab mob tsis muaj zog.
- Kev kho mob tiv thaiv kab mob: Yog tias koj muaj tus kab mob autoimmune uas lub cev ua haujlwm ntau dhau thiab tawm tsam koj lub cev, cov tshuaj no yog muab los ua kom lub cev tiv thaiv kab mob qeeb.
- Kev ntxiv ntshav lossis cov ntshav hauv lub cev: Yog tias muaj qhov tsis txaus ntawm cov protein sib xyaw, cov protein ntawd tuaj yeem nkag mus rau hauv lub cev los ntawm kev muab cov ntshav sab nraud.
- Kev Txhaj Tshuaj Tiv Thaiv Kab Mob: Vim yog lub cev tiv thaiv kab mob tsis muaj zog, koj tus kws kho mob yuav pom zoo kom txhaj tshuaj tiv thaiv kab mob, xws li kab mob pneumococcal , los tiv thaiv koj ntawm cov kab mob loj xws li mob ntsws.
- Kev kho mob qog noj ntshav: Yog tias qhov teeb meem cuam tshuam nrog qog noj ntshav, kev kho mob kom raug yuav raug sau tseg.
Peb yuav ua li cas kom peb lub cev noj qab nyob zoo?
Yog hais qhov tseeb, koj tsis tuaj yeem qhib/kaw lub khawm ncaj qha rau hauv lub kaw lus complement. Peb tsis tuaj yeem hloov nws txoj haujlwm ncaj qha. Tab sis, peb tuaj yeem ua kom peb lub cev tiv thaiv kab mob muaj zog thiab noj qab nyob zoo. Ces lub kaw lus complement kuj yuav ua haujlwm zoo.
Yog li, ua cov yam yooj yim no kom saib xyuas koj lub cev tag nrho:
- Noj zaub mov kom zoo: Noj zaub mov zoo uas muaj zaub, txiv hmab txiv ntoo, thiab cov protein huv.
- Ua kom lub cev muaj zog tsis tu ncua: Ua kom lub cev muaj zog tsawg kawg yog 30 feeb hauv ib hnub.
- Ua kom huv si: Ntxuav koj txhais tes kom huv si ua ntej noj mov thiab tom qab siv chav dej.
- Pw tsaug zog txaus: Pw tsaug zog tsawg kawg yog 7-8 teev hauv ib hnub. Lub cev tiv thaiv kab mob kho nws tus kheej thaum peb pw tsaug zog.
- Tiv thaiv koj tus kheej ntawm kev raug mob: Siv cov kev ceev faj thaum ua cov haujlwm txaus ntshai.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Lub cev sib txuas lus yog ib feem ntawm peb lub cev tiv thaiv kab mob. Nws yog thawj kab kev tiv thaiv uas tiv thaiv peb ntawm cov kab mob.
- Qhov tsis txaus ntawm cov protein hauv lub cev no tuaj yeem ua rau muaj kev kis kab mob ntau zaus, thiab kev ua haujlwm ntau dhau tuaj yeem ua rau muaj cov kab mob autoimmune.
- Yog tias koj mob tas li, nkees heev, lossis mob pob qij txha, nws yog ib qho tseem ceeb uas yuav tsum nrog kws kho mob tham yam tsis txhob tsis quav ntsej.
- Txawm hais tias peb tsis tuaj yeem tswj tau lub cev no ncaj qha los, peb tuaj yeem ua kom peb lub cev tiv thaiv kab mob muaj zog los ntawm kev ua neej noj qab haus huv (zaub mov zoo, kev tawm dag zog, thiab kev pw tsaug zog).
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus