Nws nyuaj rau piav qhia txog kev ntshai, kev ntxhov siab, thiab kev tsis paub tseeb uas los nrog kev kuaj pom tias muaj mob qog noj ntshav hauv lub mis. Tab sis qhov tseem ceeb tshaj plaws uas koj yuav tsum paub yog tias kev kho mob qog noj ntshav tau nce qib ntau heev niaj hnub no. Hnub no, peb yuav tham txog ib qho kev kho mob tshiab, siab heev. Nws hu ua Datroway. Cia peb saib Datroway yog dab tsi thiab seb nws puas tuaj yeem pab koj.
Datroway yog hom tshuaj dab tsi? Nws ua haujlwm li cas?
Hais yooj yim xwb, Datroway yog kev kho mob uas tsom mus rau ib qho kev siv thev naus laus zis tshiab. Hauv kev kho mob, peb hu qhov no ua Antibody Drug Conjugate (ADC) . Xav txog nws zoo li kev pabcuam xa khoom tshwj xeeb. Cov tshuaj no muaj peb ntu tseem ceeb.
1. Tshuaj Tiv Thaiv Kab Mob: Qhov no yog peb tus neeg xa khoom "nrhiav chaw nyob". Nws nrhiav tau ib qho protein tshwj xeeb (ib qho protein hu ua Trop-2) ntawm qhov chaw ntawm cov hlwb qog noj ntshav thiab txuas rau nws. Nws txoj haujlwm yog xaiv tua thiab ntes cov hlwb qog noj ntshav xwb, yam tsis ua rau cov hlwb noj qab nyob zoo raug mob.
2. Tshuaj kho mob qog noj ntshav ( kev kho mob qog nqaij hlav ): Qhov no yog "pob khoom" hauv lub thawv xa ntawv. Qhov no yog cov tshuaj uas rhuav tshem cov hlwb qog noj ntshav.
3. Tus Txuas: Qhov no txuas cov tshuaj tiv thaiv kab mob thiab cov tshuaj tiv thaiv kab mob qog noj ntshav. Ob qho no raug khi ua ke thaum mus ncig hauv cov ntshav, thiab tom qab ntawd sib cais tom qab nkag mus rau hauv lub cell qog noj ntshav.
Yog li, thaum cov tshuaj Datroway nkag mus rau hauv lub cev, cov tshuaj tiv thaiv kab mob hauv nws ncaj qha nrhiav cov hlwb qog noj ntshav thiab txuas nws tus kheej. Tom qab ntawd, qhov txuas ntawd raug rhuav tshem, tso cov tshuaj tiv thaiv kab mob qog noj ntshav ncaj qha mus rau hauv lub hlwb qog noj ntshav. Ua li no, lub hlwb qog noj ntshav raug rhuav tshem sab hauv. Qhov zoo tshaj plaws ntawm txoj kev no yog tias kev puas tsuaj rau cov hlwb noj qab haus huv raug txo qis heev.
Kev kho mob Datroway muab li cas?
Datroway yog ib qho kev kho mob uas muab rau hauv tsev kho mob, chaw kho mob, lossis chaw kho mob nyob rau hauv kev saib xyuas ntawm koj tus kws kho mob. Nws yog muab ua cov kua saline los ntawm cov leeg ntshav (intravenous - IV infusion ) .
- Kev Noj Tshuaj: Qhov kev noj tshuaj uas koj tau txais yog txiav txim siab los ntawm koj qhov hnyav.
- Teem Sijhawm: Kev kho mob no feem ntau yog muab txhua peb lub lis piam . Koj tus kws kho mob yuav txiav txim siab seb koj xav tau pes tsawg zaug.
- Kev Npaj Ua Ntej: Ua ntej muab cov tshuaj saline rau koj, koj yuav tau txais lwm yam tshuaj los tiv thaiv kev xeev siab, ntuav, thiab lwm yam kev tsis haum tshuaj uas yuav tshwm sim vim yog cov tshuaj saline.
- Lub sijhawm kho mob:Kev kho mob thawj zaug kav li ntawm 90 feeb. Yog tias koj tsis muaj kev phiv loj thawj zaug, kev kho mob tom qab ntawd tuaj yeem muab tau hauv 30 feeb xwb.
- Kev Soj Ntsuam: Tom qab ob zaug kev kho mob thawj zaug, cov neeg ua haujlwm kho mob yuav saib xyuas koj tsawg kawg yog ib teev. Yog tias tsis muaj teeb meem, koj yuav raug saib xyuas li 30 feeb hauv cov kev kho mob tom qab thiab tom qab ntawd tso cai rau koj mus tsev.
Kuv yuav paub li cas tias qhov kev kho mob no puas yog rau kuv?
Datroway tsis yog kev kho mob rau txhua hom mob qog noj ntshav hauv lub mis . Koj tus kws kho mob tsuas yog yuav pom zoo kom siv txoj kev kho mob no yog tias koj tus mob qog noj ntshav ua tau raws li cov qauv hauv qab no:
- Tus mob qog noj ntshav yuav tsum yog cov tshuaj hormone receptor-positive thiab HER2-negative .
- Thaum tus mob qog noj ntshav tsis tuaj yeem raug phais tshem tawm tag ('unresectable') lossis tau kis mus rau lwm qhov ntawm lub cev ('metastatic').
Qhov tseem ceeb tshaj plaws yog tias kom tsim nyog rau kev kho mob no, koj yuav tsum tau txais kev kho mob endocrine thiab lwm yam kev kho mob chemotherapy ua ntej.
Yog li ntawd, qhov kev txiav txim siab zoo tshaj plaws txog seb qhov kev kho mob no puas yog rau koj yog koj tus kws kho mob qog nqaij hlav uas kho koj . Nws yuav tshuaj xyuas tag nrho koj cov ntaub ntawv kho mob thiab txiav txim siab qhov no.
Cov kev mob tshwm sim thiab yuav ua li cas los tswj lawv?
Ib yam li kev kho mob qog noj ntshav, Datroway tuaj yeem ua rau muaj qee qhov kev phiv. Tab sis qhov xov xwm zoo yog tias muaj ntau txoj hauv kev los tswj hwm feem ntau ntawm cov no. Cia peb saib cov kev phiv tseem ceeb uas yuav tshwm sim thiab koj tuaj yeem ua dab tsi txog lawv.
| Cov teebmeem sab nraud | Yuav ua li cas los tswj hwm |
|---|---|
| Teeb meem qhov muag (Qhov muag qhuav, liab, mob, pom tsis meej) | Siv cov tshuaj pleev qhov muag uas koj tus kws kho mob pom zoo kom siv tsawg kawg yog plaub zaug hauv ib hnub. Tsis txhob hnav cov iav qhov muag thaum kho mob. Qhia rau koj tus kws kho mob tam sim ntawd yog tias koj pom muaj kev hloov pauv lossis tsis xis nyob hauv koj lub qhov muag. Koj yuav raug xa mus rau kws kho qhov muag. |
| Mob qhov ncauj | Khaws ib lub thawv dej khov los yog me ntsis dej khov rau hauv koj lub qhov ncauj thaum muab cov kua ntsev rau. Siv cov tshuaj ntxuav qhov ncauj tshwj xeeb uas koj tus kws kho mob tau sau tseg raws li tau qhia. Yog tias muaj qhov mob hauv qhov ncauj tshwm sim los yog hnyav zuj zus, qhia rau koj tus kws kho mob tam sim ntawd. |
| Xeev siab thiab ntuav | Noj cov tshuaj tiv thaiv kev xeev siab uas koj tus kws kho mob tau sau tseg kom raws sijhawm, ua ntej thiab tom qab kho mob. |
Cov no yog cov kev mob tshwm sim feem ntau. Yog tias koj muaj lwm yam kev tsis xis nyob ntxiv rau cov no, tsis txhob ntshai tham nrog koj tus kws kho mob txog qhov ntawd.
Tej yam twg yuav tsum tau them sai sai rau?
Thaum noj kev kho mob Datroway, muaj ob peb yam uas koj yuav tsum tau them sai sai rau.
Cov teeb meem ntsig txog lub ntsws
Tsis tshua muaj neeg yuav mob ntsws ('Interstitial Lung Disease' lossis 'Pneumonitis') vim yog kev kho mob no. Yog li ntawd, yog tias koj muaj cov tsos mob xws li hnoos, ua pa nyuaj, ua pa nrov nrov, kub taub hau, lossis mob hauv siab , tsis txhob tsis quav ntsej thiab qhia rau koj tus kws kho mob tam sim ntawd . Yog tias tsim nyog, tus kws kho mob yuav pib kho rau nws.
Kev xeeb tub thiab kev tswj kev yug menyuam
Qhov no yog ib qho teeb meem tseem ceeb heev.
- Kev kho mob Datroway tej zaum yuav ua rau tus menyuam hauv plab tsis zoo. Yog li ntawd, koj yuav raug kuaj xyuas seb koj puas cev xeeb tub ua ntej pib kho mob.
- Yog tias koj yog ib tug poj niam uas muaj peev xwm yug tau menyuam, koj yuav tsum siv hom kev tswj kom tsis txhob muaj menyuam uas zoo heev thaum lub sijhawm kho mob thiab rau 7 lub hlis tom qab koob tshuaj kawg .
- Yog tias koj yog ib tug txiv neej thiab koj tus khub muaj peev xwm cev xeeb tub tau, koj yuav tsum siv kev tswj kom tsis txhob muaj menyuam thaum lub sijhawm kho mob thiab rau 4 lub hlis tom qab koob tshuaj kawg .
Yog koj muaj lus nug txog qhov no, tsis txhob yig nrog koj tus kws kho mob tham.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Datroway yog kev kho mob uas tsom mus rau qee hom mob qog noj ntshav hauv lub mis. Nws zoo li "lub foob pob hluav taws uas coj kev" uas nrhiav thiab rhuav tshem cov hlwb qog noj ntshav.
- Txoj kev kho mob no tsis haum rau txhua tus. Koj tus kws kho mob qog nqaij hlav yuav txiav txim siab seb nws puas yog rau koj.
- Kev kho mob no yog muab ua cov kua ntsev los ntawm cov leeg ntshav, ib zaug txhua peb lub lis piam.
- Tej zaum yuav muaj tej yam tshwm sim xws li teeb meem qhov muag, mob qhov ncauj, thiab xeev siab. Tiam sis tej no yeej tswj tau. Qhia rau koj tus kws kho mob tam sim ntawd txog tej yam tsis xis nyob.
- Yog koj muaj cov tsos mob xws li ua pa nyuaj, tsis txhob tso tseg. Nrhiav kev pab kho mob tam sim ntawd.
- Nws yog ib qho tseem ceeb kom tsis txhob cev xeeb tub thaum lub sijhawm kho mob thiab rau ib lub sijhawm tom qab ntawd.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus