Koj puas xav tias koj muaj cov qe ntshav liab ntau dhau lawm? Cia peb tham txog erythrocytosis!

Puas muaj tej lub sij hawm koj tsuas xav tias nkees, mob taub hau, lossis qaug zog xwb? Feem ntau peb tsis tau ua tib zoo saib xyuas tej yam me me no, puas yog? Txawm li cas los xij, yog tias cov qe ntshav liab hauv koj lub cev nce siab tshaj qhov pom zoo, uas yog qhov kws kho mob hu ua erythrocytosis lossis polycythemia , cov tsos mob no yuav tshwm sim. Qhov no yog ib yam dab tsi uas koj yuav tsum txhawj xeeb me ntsis txog qee zaum. Yog li, hnub no peb yuav tham txog qhov erythrocytosis yog dab tsi, vim li cas nws tshwm sim, thiab yuav ua li cas txog nws.

erythrocytosis yog dab tsi tiag?

Hais yooj yim xwb, Erythrocytosis yog thaum koj cov ntshav muaj cov qe ntshav liab (Erythrocytes) ntau dua li qub. Raws li koj paub, peb cov ntshav muaj ob ntu. Ib ntu yog ntu khov, uas yog cov qe ntshav liab, cov qe ntshav dawb, thiab cov platelets. Lwm ntu yog ntu kua, uas peb hu ua plasma. Hauv erythrocytosis, tus lej ntawm cov qe ntshav liab nce ntxiv piv rau ntu kua, uas yog plasma.

Yog koj tau txais kev kuaj ntshav, koj yuav pom ob tus nqi ntawm daim ntawv qhia: Hematocrit thiab Hemoglobin .

• Hematocrit (HCT): Qhov no qhia koj tias koj cov ntshav muaj pes tsawg feem pua ​​yog cov qe ntshav liab.
• Hemoglobin (HB): Qhov no yog ib qho protein tseem ceeb heev uas pom muaj nyob hauv cov qe ntshav liab uas nqa cov pa oxygen thoob plaws peb lub cev.

Hauv erythrocytosis, ib qho lossis ob qho tib si ntawm cov hematocrit thiab hemoglobin tus nqi yuav siab dua li qub.

Qhov kev nce ntxiv ntawm cov qe ntshav liab no cuam tshuam li cas rau lub cev?

Cov qe ntshav liab tseem ceeb rau peb lub cev. Lawv nqa cov pa oxygen los ntawm lub ntsws mus rau txhua lub cell thiab cov nqaij hauv lub cev. Qhov no yog vim li cas peb cov nqaij thiaj li tau txais kev noj qab haus huv thiab noj qab nyob zoo.

Txawm li cas los xij, yog tias cov qe ntshav liab no nce ntau dhau, teeb meem tuaj yeem tshwm sim. Nws nyob ntawm seb vim li cas cov qe ntshav liab nce ntxiv. Qee qhov teebmeem me me heev. Tej zaum koj tsuas hnov ​​​​​​mob taub hau thiab qaug zog xwb. Txawm li cas los xij, yog tias cov qe ntshav liab nce ntxiv rau qee qhov laj thawj loj, cov ntshav pib tuab. Tom qab ntawd muaj kev pheej hmoo ntawm cov mob txaus ntshai xws li cov ntshav txhaws, mob plawv lossis mob hlwb .

Yog vim li ntawd, yog tias koj muaj cov tsos mob zoo li no, nws yog ib qho tseem ceeb heev uas yuav tsum mus ntsib kws kho mob kom paub qhov ua rau muaj qhov teeb meem no. Tsuas yog thaum ntawd koj thiaj li tau txais kev kho mob zoo, txo cov tsos mob, lossis tiv thaiv cov mob txaus ntshai.

Cov hom mob erythrocytosis tseem ceeb yog dab tsi?

Erythrocytosis muaj ob hom nyob ntawm seb cov qe ntshav liab no nce li cas:

1. Kab mob ntshav liab tsis zoo: Qhov no yog thaum cov qe ntshav liab uas koj lub cev tsim tawm ntau dua li qub.

2. Mob ntshav liab (Erythrocytosis): Qhov no yog thaum cov qe ntshav liab suav tau zoo li qub, tab sis cov ntshav hauv cov ntshav tsawg zuj zus, yog li cov qe ntshav liab zoo li nce ntxiv. Piv txwv li, yog tias koj ntuav ntau thiab raws plab thiab poob dej ntau ntawm koj lub cev, cov ntshav yuav tsis ntws zoo. Qhov mob no tuaj yeem tshwm sim rau lub sijhawm zoo li no.

Erythrocytosis kiag li yog muab faib ua ob hom, nyob ntawm seb ua li cas:

Kev kuaj mob Erythrocytosis thawj zaug

Qhov teeb meem nyob rau hauv peb cov pob txha. Raws li koj paub, cov pob txha yog lub Hoobkas tseem ceeb hauv peb lub cev uas ua cov qe ntshav liab. Yog li, hauv qhov erythrocytosis thawj zaug no, vim muaj qhov tsis zoo ntawm cov noob caj noob ces hauv cov hlwb (cov hlwb progenitor) hauv cov pob txha, kev tsim cov qe ntshav liab nce ntxiv yam tsis tuaj yeem tswj tau. Qhov tsis zoo ntawm cov noob caj noob ces no tuaj yeem tau txais los ntawm niam txiv (ua qhov tsis zoo thaum yug los), lossis nws kuj tuaj yeem tshwm sim thaum lub neej.

• Tau Txais Primary Erythrocytosis: Ib qho piv txwv zoo ntawm qhov no yog ib qho mob hu ua Polycythemia Vera . Muaj ntau tus neeg tsis nkag siab txog Erythrocytosis thiab Polycythemia Vera ua tib yam kab mob. Txawm li cas los xij, lawv tsis zoo ib yam. Polycythemia Vera yog ib qho mob tshwj xeeb thiab loj heev uas ua rau Erythrocytosis.
• Kab mob Erythrocytosis uas tau txais los ntawm niam txiv: Qee zaum, cov teeb meem hauv cov noob caj noob ces uas tau txais los ntawm niam txiv tuaj yeem ua rau cov pob txha tsim cov qe ntshav liab ntau dhau.

Kev mob ntshav qab zib theem ob

Qhov teeb meem ntawm no tsis yog nyob rau hauv cov pob txha, tab sis nyob rau hauv lwm yam sab nraum cov pob txha. Feem ntau, erythrocytosis theem ob yog tshwm sim los ntawm peb lub cev tsim ntau dhau ntawm cov tshuaj hormones hu ua erythropoietin , lossis EPO . 'EPO' yog ib tug chemical messenger. Nws yog qhov uas qhia rau cov pob txha kom "ua ntau cov qe ntshav liab."

Xav txog seb, koj muaj kab mob ntsws lossis kab mob plawv. Ces cov pa oxygen uas lub cev tau txais tsawg. Lub sijhawm ntawd, lub cev sim ua ntau cov tshuaj hormone 'EPO', thiab los ntawm nws, ua rau cov pob txha pob txha ua ntau cov qe ntshav liab. Vim tias cov qe ntshav liab nqa cov pa oxygen. Txawm li cas los xij, yog tias kev tsim cov qe ntshav liab hauv txoj kev no nce ntau dhau, nws ua rau muaj erythrocytosis theem ob. Qhov erythrocytosis theem ob no kuj tuaj yeem tshwm sim los ntawm qee yam mob caj ces, tab sis cov teeb meem caj ces tsis yog cov uas nyob hauv cov pob txha pob txha.

Yuav ua li cas koj thiaj li kuaj xyuas cov ntshav kom pom tias koj puas muaj erythrocytosis?

Qhov tseeb, qib ntawm cov qe ntshav liab uas suav tias yog ib txwm muaj yuav txawv ntawm ib tus neeg mus rau ib tus neeg. Muaj ntau yam uas cuam tshuam rau qhov no, suav nrog koj lub hnub nyoog, seb koj yog txiv neej lossis poj niam, thiab qhov siab ntawm thaj chaw uas koj nyob (txawm tias koj nyob ntawm dej hiav txwv lossis hauv thaj chaw roob).

Feem ntau cov neeg laus uas muaj cov ntshav liab ntau ntau (erythrocytosis) feem ntau kuaj pom tias muaj cov hematocrit (HCT) thiab/lossis hemoglobin (HB) ntau ntxiv. Cov nqi no tuaj yeem ntsuas tau los ntawm kev kuaj ntshav hu ua "Complete Blood Count (CBC)"

Rau cov txiv neej:

• Hematocrit (HCT): Yog tias ntau dua 50%
• Hemoglobin (HB): Yog tias ntau dua 17.5 g/dL

Rau cov poj niam uas tsis cev xeeb tub:

• Hematocrit (HCT): Yog tias ntau dua 45%
• Hemoglobin (HB): Yog tias ntau dua 15.3 g/dL

Tseem Ceeb: Cov nqi no tsuas yog ib qho kev qhia dav dav xwb. Koj tus kws kho mob yuav txiav txim siab seb koj puas muaj erythrocytosis tom qab xav txog koj txoj kev noj qab haus huv tag nrho.

Cov ua rau muaj tus kab mob Erythrocytosis yog dab tsi?

Qhov no yog tshwm sim los ntawm kev txo qis ntawm cov dej hauv lub cev, uas ua rau cov ntshav ntws (plasma) txo qis thiab qhov concentration ntawm cov qe ntshav liab nce ntxiv. Yog li, qhov laj thawj tseem ceeb rau qhov no yog lub cev qhuav dej .

• ntuav hnyav heev
• Mob raws plab
• Qee cov tshuaj, piv txwv li, cov tshuaj diuretics (cov tshuaj uas tshem cov dej tawm ntawm lub cev) (Cov no yog muab rau cov ntshav siab lossis cov kua dej khaws cia).

Vim yog cov laj thawj no, cov kua dej hauv lub cev tuaj yeem txo qis thiab ua rau muaj erythrocytosis.

Dab tsi yog cov ua rau muaj Absolute Erythrocytosis?

Muaj ob qho ua rau qhov no sib cais: thawj thiab thib ob.

Ua rau muaj cov tsos mob ntawm cov ntshav erythrocytosis thawj zaug:

Qhov no feem ntau yog tshwm sim los ntawm qhov teeb meem caj ces uas cuam tshuam rau cov pob txha.

• Polycythemia Vera thiab Lwm Yam Myeloproliferative Neoplasms: Cov no yog cov mob uas cov pob txha tsim cov qe ntshav liab thiab lwm cov qe ntshav ntau dhau. Polycythemia Vera yog cov mob uas tshwm sim ntau tshaj plaws.
• Cov teeb meem thaum yug los: Ib txhia neeg yuav yug los muaj qhov teeb meem caj ces uas ua rau cov pob txha tsim cov qe ntshav liab ntau dhau.

Ua rau muaj erythrocytosis theem ob:

Qhov no feem ntau yog tshwm sim los ntawm kev nce ntxiv ntawm cov tshuaj hormone 'EPO'.

• Cov mob uas txo cov pa oxygen rau cov nqaij:
• Kab mob ntsws (piv txwv li mob ntsws ntev, mob ntsws emphysema)
• Kab Mob Plawv (piv txwv li, muaj teeb meem plawv txij thaum yug los)
• Kev pw tsaug zog tsis taus pa
• Hemoglobinopathy: Cov no yog cov mob uas cov protein hemoglobin hauv cov qe ntshav liab tsis tuaj yeem nqa oxygen tau zoo vim muaj qhov tsis zoo.
• Cov kab mob raum thiab kev hloov pauv:
• Renal Artery Stenosis (kev nqaim ntawm cov hlab ntsha uas muab cov ntshav rau lub raum)
• Hydronephrosis (o ntawm lub raum vim muaj cov zis ntau dhau)
• Qhov mob no qee zaum tuaj yeem tshwm sim txawm tias tom qab hloov raum lawm los xij.
• Cov qog nqaij hlav: Qee cov qog nqaij hlav uas muaj mob qog nqaij hlav thiab tsis muaj mob qog nqaij hlav tuaj yeem tso tawm cov tshuaj hormone EPO ntau dhau.
• Cov qog nqaij hlav: Renal Cell Carcinoma, Hemangioblastoma, Hepatocellular Carcinoma, Parathyroid Carcinoma.
• Cov qog nqaij hlav uas tsis yog mob qog noj ntshav: Uterine Fibroids, Pheochromocytoma, Meningioma.
• Kev lom carbon monoxide thiab kev haus luam yeeb: Kev haus luam yeeb ntau dhau tuaj yeem ua rau muaj kev lom carbon monoxide, uas tuaj yeem txo cov pa oxygen rau cov nqaij.
• Qee cov tshuaj thiab cov tshuaj:
• Cov tshuaj Anabolic Steroids (cov neeg ncaws pob noj kom muaj zog ntxiv)
• Kev noj cov tshuaj hormone testosterone.

Cov tsos mob ntawm tus neeg uas muaj erythrocytosis yuav muaj li cas?

Cov tsos mob uas koj muaj (thiab lawv hnyav npaum li cas) nyob ntawm seb ua rau koj cov ntshav liab erythrocytosis ua rau dab tsi. Piv txwv li, ib tus neeg uas muaj cov ntshav liab erythrocytosis theem ob yuav muaj cov tsos mob xws li:

• Mob taub hau
• Tsis meej pem, muaj teeb meem tsom ntsoov
• Nyuaj siab tsaug zog
• Xav tias tsis muaj zog, nkees

Ib tug neeg uas muaj cov ntshav liab thawj zaug (tshwj xeeb tshaj yog polycythemia vera) yuav muaj cov tsos mob hnyav dua:

• Ntshav Siab
• Tawm hws ntau dhau thaum hmo ntuj
• Kev poob phaus tsis muaj laj thawj
• Mob hnyav, o, thiab liab ntawm cov pob qij txha (tseem hu ua gout )
• Teeb meem los ntshav (ntau zaus los ntshav ntswg, los ntshav lossis mob nqaij txawm tias yog raug mob me me)
• Tawv nqaij khaus (khaus yuav nce ntxiv, tshwj xeeb tshaj yog tom qab da dej kub)
• Kev tsis muaj zog ntawm ob txhais ceg, zoo li cov ntsaum khiav ib puag ncig
• Liab nrog rau o ntawm lub ntsej muag, tes, thiab taw.

Cov kws kho mob kuaj mob erythrocytosis li cas?

Koj tus kws kho mob yuav sim txiav txim seb ua li cas koj cov qe ntshav liab ntau, siv ntau yam kev kuaj thiab cov txheej txheem.

Ua ntej, lawv yuav nug cov lus nug txog koj keeb kwm kev kho mob, cov tshuaj uas koj noj, koj txoj kev ua neej (piv txwv li, koj puas haus luam yeeb), thiab koj cov tsos mob, thiab kuaj xyuas seb puas muaj cov ntshav liab (erythrocytosis ) (uas yog los ntawm kev txo qis hauv cov ntshav hauv cov ntshav). Lawv kuj tseem yuav kuaj lub cev.

Qhov tom ntej uas yuav tsum xyuas yog seb koj puas muaj thawj lossis thib ob . Koj tuaj yeem ua ob peb qhov kev sim ntxiv nrog cov ntaub ntawv tau hais los saum toj no.

Cov kev ntsuam xyuas twg tab tom ua?

• Kev suav cov ntshav tag nrho (CBC): Qhov no tuaj yeem kuaj xyuas koj cov ntshav liab, hemoglobin (HB), thiab hematocrit (HCT).
• Kev Ntsuas Ntshav Ntawm Sab Nraud (PBS): Qhov no suav nrog kev muab ib tee ntshav thiab saib cov cell hauv qab lub tshuab microscope kom pom tias lawv puas txawv txav hauv cov duab lossis qhov loj. Yog tias koj muaj mob zoo li Polycythemia Vera, koj yuav pom cov cell txawv txav.
• Kev Ntsuas Kev Ua Haujlwm ntawm Lub Raum thiab Siab: Qhov no tuaj yeem muab lub tswv yim seb puas muaj kab mob raum lossis qog uas tsim EPO ntau dhau.
• Kev ntsuas pa oxygen hauv cov ntshav: Ib lub cuab yeej me me uas muab tso rau ntawm tus ntiv tes ntsuas qib pa oxygen hauv cov ntshav. Qhov no tuaj yeem pab txiav txim siab seb qhov mob puas yog los ntawm tej yam xws li kab mob plawv lossis kab mob ntsws.
• Tshawb xyuas qib ntawm erythropoietin (EPO): Yog tias qib ntawm 'EPO' qis, nws yuav yog thawj erythrocytosis, yog tias qib ntawm 'EPO' siab, nws yuav yog erythrocytosis theem ob.
• Kev Kuaj Zis: Yuav muab cov zis coj mus kuaj seb puas muaj qhov tsis zoo. Yog tias muaj cov qe ntshav liab nyob hauv cov zis, tej zaum nws yog vim muaj kab mob raum.

Yog tias tus kws kho mob xav tias muaj mob tshwj xeeb, xws li polycythemia vera, nws kuj tseem yuav ua lwm yam kev kuaj mob, xws li kev kuaj pob txha .

Yuav kho tus kab mob erythrocytosis li cas?

Feem ntau, qhov ua rau muaj erythrocytosis tsis tuaj yeem kho tau tag nrho. Txawm li cas los xij, kev kho mob tuaj yeem tswj thiab txo cov tsos mob. Hauv cov xwm txheej ntawm erythrocytosis uas tshwm sim los ntawm cov laj thawj loj, kev kho mob kuj tseem siv los tiv thaiv cov mob txaus ntshai xws li cov ntshav txhaws.

• Kev phais ntshav los yog kev phais Venesection:

Qhov no yog kev kho mob feem ntau rau polycythemia vera. Nws zoo li pub ntshav, tab sis nws yuav tsum tau noj me ntsis ntshav los ntawm cov leeg ntshav thiab txo cov qe ntshav liab thiab cov ntshav uas ntau dhau. Feem ntau erythrocytosis theem ob tsis xav tau kev kho mob no.

• Cov Tshuaj:
• Rau cov neeg uas muaj feem yuav mob ntshav txhaws, kws kho mob yuav pom zoo kom noj tshuaj aspirin tsawg tsawg txhua hnub.
• Kuj tseem muaj cov tshuaj uas txo cov qe ntshav liab:
• Hydroxycarbamide (Hydroxycarbamide)
• Hydroxyurea `(Hydroxyurea)`
• Busulfan
• Interferon alfa `(Interferon alfa`)`
• Ruxolitinib

Koj tus kws kho mob yuav sau ntawv kom koj noj cov tshuaj uas haum rau koj tus mob. Lawv kuj tseem yuav sau ntawv kom koj noj cov tshuaj uas ua rau koj mob, nyob ntawm seb koj tus mob erythrocytosis yog dab tsi.

Yog tias kuv muaj tus mob no, kuv yuav tsum xav li cas?

Koj qhov kev paub yuav nyob ntawm seb ua rau koj cov ntshav liab erythrocytosis thiab nws hnyav npaum li cas. Piv txwv li, qee yam mob uas tau los ntawm noob caj ces ntawm cov ntshav liab thawj zaug tsuas yog ua rau muaj cov tsos mob me me xwb thiab tsis ua rau tuag taus. Txawm li cas los xij, cov mob hnyav dua, xws li polycythemia vera, yuav xav tau kev kho mob mus tas li.

Kuv yuav saib xyuas kuv tus kheej li cas?

Qhov tseem ceeb tshaj plaws yog ua raws li koj tus kws kho mob cov lus qhia kom meej. Lub sijhawm no, muaj ob peb txoj kev hloov pauv hauv lub neej uas yuav pab tau koj:

• Yog koj haus luam yeeb, tsum.
• Tswj koj lub cev kom muaj qhov hnyav zoo.
• Yog koj muaj ntshav siab, tswj nws.
• Tsis txhob mus ncig ntawm dej hiav txwv mus rau qhov chaw siab heev (thaj chaw roob) ntau li ntau tau.

Kuv yuav tsum mus rau tsev kho mob sai sai (ETU) thaum twg?

Yog tias koj muaj ib qho mob ntsig txog erythrocytosis uas ua rau koj muaj feem yuav muaj ntshav txhaws, nws yog ib qho tseem ceeb uas yuav tsum paub txog cov tsos mob ntawm cov ntshav txhaws. Yog tias koj muaj ib qho ntawm cov tsos mob hauv qab no, nrhiav kev kho mob tam sim ntawd:

• Kab Mob Ntshav Hauv Cov Hlab Ntshav (DVT): o, mob, thiab liab ntawm ib ceg.
• Ntshav txhaws hauv lub ntsws (Pulmonary Embolism - PE): Mob hauv siab, ua pa nyuaj, kiv taub hau.
• Mob stroke: Tsis muaj zog tam sim ntawd, tsis sib npaug, tsis sib koom tes, cov leeg nqaij tsis muaj zog lossis tsis muaj zog ntawm ib sab ntawm lub cev.
• Mob plawv nres: Mob hauv siab, ua tsis taus pa, kiv taub hau, tawm hws.

Yog koj muaj ib qho ntawm cov tsos mob no, thov mus ntsib kws kho mob tam sim ntawd yam tsis muaj kev ncua.

Thaum kawg, tej yam yuav tsum nco ntsoov (Cov Lus Coj Mus Tsev)

Erythrocytosis yog qhov muaj cov qe ntshav liab ntau ntxiv hauv koj cov ntshav. Qhov no tuaj yeem yog ib qho mob me me, lossis qee zaum nws tuaj yeem yog ib qho cim qhia txog mob hnyav.

• Yog koj muaj tej yam tsos mob txawv txawv (tshwj xeeb yog qaug zog tas li, mob taub hau, tawv nqaij tawm pob, ua pa nyuaj), mus ntsib kws kho mob.
• Tus kws kho mob yuav txiav txim seb yog vim li cas koj cov qe ntshav liab ntau.
• Qee zaum, kev hloov pauv yooj yim ntawm kev ua neej (piv txwv li, txo cov tshuaj uas koj noj, kho qhov qhuav dej) tuaj yeem daws qhov teeb meem no.
• Yog tias erythrocytosis yog los ntawm ib qho mob hnyav dua, koj tus kws kho mob yuav saib xyuas koj tsis tu ncua thiab muab kev kho mob tsim nyog rau koj.

Kev saib xyuas koj txoj kev noj qab haus huv yog qhov tseem ceeb heev, yog li ntawd, yog tias koj muaj kev txhawj xeeb, tsis txhob ntshai tham nrog kws kho mob.

Erythrocytosis , polycythemia, cov qe ntshav liab, hemoglobin, hematocrit, ntshav txhaws, pob txha