Koj cov ntshav puas muaj phosphate tsawg? Cia peb tham txog qhov mob no '(Hypophosphatemia)'!

Tej zaum koj twb pom ib yam dab tsi hu ua "Phosphate" thaum koj saib daim ntawv qhia txog ntshav, puas yog? Los yog tej zaum tus kws kho mob tau qhia koj txog nws. Cov phosphate no yeej tseem ceeb heev rau peb lub cev. Yog li, yuav ua li cas yog tias cov phosphate no txo ​​qis hauv cov ntshav? Qhov ntawd yog qhov peb hu ua '(Hypophosphatemia)'. Cia peb tham txog qhov no kom meej, yooj yim heev, hnub no.

Txhais li cas yog tias cov phosphate qis? Puas yog nws '(Hypophosphatemia)'?

Hais yooj yim xwb, yog lawm. Hypophosphatemia yog ib qho mob uas cov minerals hu ua phosphate hauv koj cov ntshav qis. Phosphate yog ib qho electrolyte uas tseem ceeb rau ntau yam haujlwm hauv peb lub cev. Nws ua haujlwm zoo li lub roj teeb hauv peb lub cev. Qhov mob no tuaj yeem tsis hnyav heev lossis tsis hnyav heev. Nws kuj tuaj yeem tshwm sim sai sai (mob hnyav) lossis dhau sijhawm (mob ntev).

Yog li, cov phosphate no tseem ceeb npaum li cas rau lub cev?

Xav txog seb cov phosphate no ua haujlwm ntau npaum li cas hauv peb lub cev!

• Tsim peb cov pob txha thiab cov hniav thiab ua kom lawv muaj zog: 85% ntawm cov phosphorus hauv peb lub cev yog nyob rau hauv peb cov pob txha. Yog li qhov no yog qhov tseem ceeb rau cov pob txha muaj zog.
• Ua kom lub paj hlwb ua haujlwm kom zoo: Peb cov hlab ntsha xav tau phosphate kom ua haujlwm tau zoo.
• Pab cov leeg nqaij sib zog: Thaum peb txav peb txhais tes thiab ob txhais ceg, thiab thaum peb lub plawv dhia, peb cov leeg nqaij sib zog, yog li qhov no kuj pab nrog qhov ntawd.

Peb tau txais cov phosphorus/phosphate no los ntawm cov khoom noj uas peb noj.

Qhov tseem ceeb, qib phosphate hauv peb cov ntshav muaj feem cuam tshuam ncaj qha rau qib calcium. Ob qho ua haujlwm rov qab. Qhov ntawd yog, thaum qib calcium hauv cov ntshav nce ntxiv, qib phosphate txo qis. Qhov no tshwm sim txhua ob. Cov tshuaj parathyroid hormone (PTH), uas yog tsim los ntawm cov qog parathyroid hauv peb lub caj dab, tswj cov qib calcium thiab phosphate no.

Tus mob no (Hypophosphatemia) muaj ntau npaum li cas?

Kab mob phosphate hauv cov ntshav me me yog ib qho mob uas pom muaj ntau hauv kev kuaj ntshav. Qee cov ntawv tshaj tawm qhia tias nws cuam tshuam txog li 5% ntawm cov pej xeem hauv Tebchaws Meskas. Feem ntau, nws tsis yog ib qho mob hnyav thiab tsis ua rau muaj tsos mob. Nws feem ntau pom tau los ntawm kev ua yuam kev.

Txawm li cas los xij, cov neeg uas muaj mob hnyav heev uas muaj cov phosphate hypophosphatemia sai sai (acute, severe hypophosphatemia) feem ntau yuav muaj cov mob no. Piv txwv li:

• Rau cov neeg uas quav dej cawv (Alcohol use disorder)
• Yog tias muaj ketoacidosis (DKA) uas cuam tshuam nrog ntshav qab zib
• Thaum muaj kab mob hnyav, sepsis
• Rau cov neeg uas muaj kev kub hnyiab loj

Tus mob no tuaj yeem pom tau txog li 80% ntawm cov neeg zoo li no.

Yog li, cov tsos mob ntawm '(Hypophosphatemia)' yog dab tsi?

Cov tsos mob nyob ntawm seb cov phosphate qis npaum li cas.

Hypophosphatemia me ntsis

Cov neeg uas muaj cov tshuaj phosphate hauv lub cev me ntsis feem ntau tsis muaj tsos mob , tab sis qee tus yuav muaj cov leeg nqaij tsis muaj zog thiab qaug zog me ntsis.

Yog tias nws hnyav heev (Hnyav Hypophosphatemia)

Txawm li cas los xij, yog tias cov phosphate qis heev (hypophosphatemia hnyav), cov tsos mob hauv qab no yuav tshwm sim, thiab cov no yuav tsum tsis txhob saib tsis taus :

• Mob hauv cov leeg thiab pob txha
• Cov leeg nqaij tsis muaj zog heev
• Kev hloov pauv ntawm lub siab - piv txwv li, tsis muaj peev xwm tsom ntsoov, yooj yim chim siab
• Ua tsis taus pa lossis lub plawv tsis ua haujlwm
• Kev xav tias tsis muaj zog, txo qis kev teb
• Muaj kev mob nkeeg (mob qaug dab peg)

Qhov no tseem ceeb heev: Yog tias tsis kho sai sai rau qhov mob hypophosphatemia hnyav , nws tuaj yeem ua rau tsis nco qab thiab txawm tias tuag . Yog li ntawd, yog tias koj lossis ib tus neeg koj paub muaj cov tsos mob hnyav no, koj yuav tsum mus rau tsev kho mob ze tshaj plaws tam sim ntawd.

Yog tias nws tau muaj ntev lawm (Chronic Hypophosphatemia)

Cov neeg uas muaj cov phosphate qis ntev (chronic hypophosphatemia) yuav muaj cov tsos mob xws li:

• Mob hauv cov pob txha
• Pob txha tawg
• Tsis muaj zog
• Kev ntshaw noj mov

Cov menyuam yaus uas muaj cov phosphate qis dhau lub sijhawm ntev yuav muaj cov tsos mob ntawm tus mob hu ua rickets , uas suav nrog:

• Poob qhov siab rau hnub nyoog
• Cov ceg zoo li lub hneev
• Qhov dav ntawm thaj chaw ntawm lub dab teg thiab pob luj taws vim muaj kev hloov pauv ntawm cov pob txha

Yog tias koj lossis koj tus menyuam muaj cov tsos mob no, nws yog ib qho tseem ceeb heev uas yuav tsum nrhiav kev pab kho mob.

Cov ua rau muaj '(Hypophosphatemia)' yog dab tsi?

Muaj ntau yam ua rau mob no tshwm sim. Cov ua rau mob no txawv nyob ntawm seb nws puas mob me me lossis mob hnyav, mob tam sim ntawd, lossis mob ntev.

Cov ua rau muaj hypophosphatemia nruab nrab thiab hnyav

Qhov tsis txaus phosphate nruab nrab mus rau hnyav heev tuaj yeem tshwm sim hauv cov xwm txheej hauv qab no:

• Thaum lub sijhawm rov zoo los ntawm tus kab mob ntshav qab zib ketoacidosis (DKA)
• Kev siv cawv thiab kev tshem tawm cawv
• Kub hnyiab hnyav heev
• Kab mob rov qab noj mov dua : Qhov no nyuaj me ntsis. Hais yooj yim xwb, nws yog qhov rov qab noj mov sai sai tom qab lub sijhawm yoo mov, uas ua rau muaj kev hloov pauv txaus ntshai, qee zaum txaus ntshai rau lub neej, hauv cov kua dej thiab electrolyte hauv lub cev.
• Alkalosis ua pa hnyav heev: Qhov no yog thaum tsis muaj carbon dioxide txaus hauv cov ntshav.

Cov ua rau muaj hypophosphatemia ntev

• Cov tshuaj hormones parathyroid ntau ntxiv, piv txwv li hauv tus mob "Hyperparathyroidism".
• Lwm yam kev tsis sib npaug ntawm cov tshuaj hormones, xws li Cushing's syndrome.
• Tsis txaus Vitamin D.
• Malabsorption yog ib qho mob uas cov khoom noj tsis nqus tau zoo vim yog kev tsis noj qab haus huv thiab teeb meem plab hnyuv.
• Lwm yam electrolyte tsis sib npaug, xws li magnesium tsawg (hypomagnesemia) thiab potassium tsawg (hypokalemia).
• Kev kho mob rau qhov tsis muaj hlau yog kev txhaj tshuaj hlau rau hauv cov leeg ntshav, tshwj xeeb yog hom hu ua ferric carboxymaltose (FCM). Qhov no feem ntau tshwm sim thaum noj hlau tas li li no.
• Siv cov tshuaj diuretic ntev heev.
• Siv cov tshuaj antacids uas khi phosphate ntau zaus los yog ntau dhau, uas yuav los ntawm lub tsev muag tshuaj yam tsis tau kev qhia los ntawm kws kho mob. Qhov no suav nrog cov tshuaj antacids uas muaj txhuas, calcium, thiab magnesium.
• Kev lom los ntawm cov tshuaj hu ua theophylline, uas muab rau cov poj niam cev xeeb tub.

Cov neeg uas muaj kab mob raum hnyav heev (tshwj xeeb tshaj yog cov uas tab tom ntxuav ntshav) noj cov tshuaj hu ua "phosphate binders" nrog pluas noj, uas lawv tus kws kho mob raum tau sau ntawv kom txo qhov nqus tau phosphate los ntawm cov zaub mov. Cov no kuj tseem tuaj yeem ua rau cov phosphate qis yog tias siv mus sij hawm ntev.

Yuav kuaj mob li cas rau tus mob "Hypophosphatemia" no?

Qhov no yooj yim heev rau kev kuaj mob. Tus kws kho mob yuav kuaj ntshav los xyuas seb koj cov phosphate nyob rau hauv koj cov ntshav muaj pes tsawg . Yog tias koj cov phosphate concentration hauv koj cov ntshav tsawg dua 2.5 milligrams ib deciliter (mg/dL), ces lawv hais tias koj muaj "Hypophosphatemia".

Cov ntshav phosphate ib txwm muaj rau cov neeg laus yog ntawm 2.5 thiab 4.5 mg/dL, thiab rau cov menyuam yaus, nws yog ntawm 4.5 thiab 6.5 mg/dL. Txawm li cas los xij, cov nqi no tuaj yeem txawv me ntsis ntawm chav kuaj mus rau chav kuaj.

Feem ntau, tshwj xeeb tshaj yog thaum muaj mob hypophosphatemia hnyav heev, qhov ua rau muaj mob no yuav pom tseeb los ntawm koj keeb kwm mob thiab cov tsos mob.

Vim tias hypophosphatemia feem ntau yog qhov tshwm sim ntawm lwm yam mob, koj tus kws kho mob yuav xaj kom kuaj ntxiv kom paub qhov ua rau thiab soj ntsuam koj txoj kev noj qab haus huv tag nrho. Cov no yuav suav nrog:

• Lwm cov kev kuaj ntshav: Kev kuaj lub raum ua haujlwm, kev kuaj ntshav calcium, kev kuaj ntshav vitamin D.
• Kev kuaj zis.
• Tej zaum cov duab scans.

Cov kev kho mob rau '(Hypophosphatemia)' yog dab tsi?

Txoj kev kho mob tseem ceeb yog kho qhov ua rau muaj tus mob no, thaum tseem kho cov phosphate hauv cov ntshav.

Cov neeg uas muaj cov tshuaj phosphate hauv lub cev me me mus rau nruab nrab feem ntau yuav tau noj cov tshuaj phosphate hloov cov tshuaj noj. Koj tus kws kho mob kuj tseem yuav pom zoo kom noj cov khoom noj uas muaj phosphorus ntau.

Txawm li cas los xij, yog tias qhov mob hnyav heev, phosphate raug muab rau hauv cov hlab ntsha (los ntawm IV) .

Puas muaj dab tsi uas peb ua tau los tiv thaiv qhov teeb meem no?

Tau kawg, tsis yog txhua rooj plaub ntawm hypophosphatemia tuaj yeem tiv thaiv tau, tshwj xeeb tshaj yog cov uas hnyav thiab sai sai. Txawm li cas los xij, kev noj zaub mov zoo thiab sib npaug tuaj yeem pab tiv thaiv cov phosphate me me.

Cov khoom noj twg muaj phosphorus ntau?

• Nqaij, ntses thiab lwm yam protein: Cov khoom xws li qe, nqaij qaib, qaib ntxhw, nqaij npuas, khoom noj hiav txwv, thiab siab.
• Cov khoom noj siv mis: mis nyuj, cheese, cheese tsev, yogurt.
• Cov txiv ntoo thiab noob: txiv ntseej almond, txiv laum huab xeeb, txiv ntseej Brazil, noob taub dag, noob hnav.

Tseem Ceeb: Ua ntej koj hloov koj cov zaub mov noj kom loj, nco ntsoov nrog kws kho mob lossis kws noj haus tham.

Yog tias koj muaj ib yam mob uas ua rau koj muaj feem yuav mob hypophosphatemia ntau dua, xws li hyperparathyroidism, malabsorption teeb meem, lossis vitamin D deficiency, nws yog ib qho tseem ceeb uas yuav tsum mus ntsib koj tus kws kho mob tsis tu ncua thiab ua raws li koj txoj kev npaj kho mob. Qhov no tuaj yeem pab tiv thaiv hypophosphatemia.

Yuav muaj dab tsi tshwm sim yav tom ntej? (Kev kwv yees)

Qhov kev kwv yees ntawm tus mob no nyob ntawm seb nws puas yog mob me me lossis mob hnyav, pib mob tam sim ntawd, lossis mob ntev. Cov mob me me feem ntau teb tau zoo rau kev kho mob, txhais tau tias lawv tuaj yeem kho tau. Txawm li cas los xij, cov mob hnyav, pib mob tam sim ntawd tuaj yeem ua rau muaj teeb meem loj yog tias tsis kho sai.

Puas muaj teeb meem tshwm sim vim yog '(Hypophosphatemia)'?

Yog, yog tias tsis kho, tshwj xeeb tshaj yog tias muaj kev txo qis ntawm phosphate mus sij hawm ntev (chronic hypophosphatemia), ib qho mob hu ua osteomalacia tuaj yeem tshwm sim. Hais yooj yim, qhov no yog thaum cov pob txha mos thiab tawg yooj yim .

Raws li tau hais ua ntej lawm, yog tias koj muaj cov tsos mob hnyav ntawm hypophosphatemia, xws li mob nqaij tsis paub meej thiab hloov pauv ntawm lub hlwb, nws yog ib qho tseem ceeb heev uas yuav tsum mus rau tsev kho mob ze tshaj plaws sai li sai tau.

Thaum kawg, nco ntsoov qhov no.

Yog li, cov phosphate uas peb tau tham txog hnub no yog ib qho "electrolyte" tseem ceeb heev hauv peb cov ntshav. Tej zaum yuav pom tias muaj phosphate txo qis me ntsis ("mild hypophosphatemia") ntawm kev kuaj ntshav thiab tsis yog ib yam dab tsi uas yuav tsum txhawj txog. Yog tias qhov ntawd tshwm sim, koj tus kws kho mob yuav qhia koj kom noj ntau yam khoom noj uas muaj phosphorus ntau.

Txawm li cas los xij, yog tias koj muaj mob lossis muaj tus cwj pwm uas ua rau koj muaj feem yuav tsis muaj phosphate txaus, xws li haus cawv ntau dhau lossis tsis nqus tau cov as-ham hauv plab hnyuv, nws yog qhov zoo tshaj plaws los tham nrog koj tus kws kho mob txog qhov no. Nug lawv seb yuav ua li cas thiaj tiv thaiv tau hypophosphatemia thiab cov tsos mob twg uas yuav tsum tau saib xyuas. Nco ntsoov, koj tus kws kho mob yog koj tus phooj ywg zoo tshaj plaws hauv koj txoj kev noj qab haus huv. Lawv tuaj yeem pab koj.

`Hypophosphatemia, phosphate, phosphorus, electrolytes, phosphate qis, kev kuaj ntshav, kev noj zaub mov zoo, phosphate, phosphorus, kev kuaj ntshav, kev noj zaub mov zoo