Nws yog ib qho ib txwm muaj kev ntshai thiab kev ntxhov siab thaum koj tus kws kho mob qhia koj tias ib tug neeg hauv koj tsev neeg, tej zaum koj niam lossis koj txiv uas koj hlub, muaj tus kab mob Parkinson. Txawm hais tias tseem tsis tau muaj kev kho rau tus kab mob no, muaj ntau yam tshuaj zoo uas tuaj yeem pab tswj cov tsos mob thiab tswj kom muaj lub neej zoo. Yog li hnub no, cia peb tham txog cov tshuaj no yog dab tsi, lawv ua haujlwm li cas, thiab peb yuav tsum paub txog dab tsi.
Vim li cas tus kab mob Parkinson thiaj tshwm sim? Yuav ua li cas tshwm sim nrog kev siv tshuaj?
Hais yooj yim xwb, tus kab mob Parkinson yog ib qho mob hlwb uas zuj zus tuaj uas cuam tshuam rau lub cev txoj kev txav mus los. Nws yog tshwm sim los ntawm kev poob qis ntawm cov hlwb hauv lub hlwb, tshwj xeeb tshaj yog nyob rau hauv ib feem ntawm lub hlwb hu ua substantia nigra uas tswj kev txav mus los. Cov hlwb no tsim cov neurotransmitter hu ua dopamine .
Xav txog nws, ib yam tshuaj hu ua dopamine yog qhov tseem ceeb rau peb lub cev kom txav mus los tau zoo, zoo li tsav tsheb ntawm txoj kev tsis muaj tsheb sib tsoo. Hauv tus kab mob Parkinson, kev tsim cov dopamine no txo qis, ua rau muaj cov tsos mob xws li kev txav qeeb, tshee hnyo, thiab mob nqaij.
Yog li ntawd, lub hom phiaj tseem ceeb ntawm ntau cov tshuaj rau tus kab mob Parkinson yog los tswj cov qib dopamine qis hauv lub hlwb.
Cov tshuaj siv feem ntau
Feem ntau cov kws kho mob sau ntawv kom siv ntau yam tshuaj rau cov neeg mob Parkinson, tsis yog ib yam xwb. Cia peb saib cov tshuaj tseem ceeb.
| Pawg Tshuaj | Nws Ua Haujlwm Li Cas | Cov ntaub ntawv tseem ceeb |
|---|---|---|
| Levodopa thiab Carbidopa | Levodopa yog ib yam tshuaj uas mus rau lub hlwb thiab hloov mus ua dopamine. Tab sis vim nws raug rhuav tshem hauv lub cev ua ntej nws mus txog lub hlwb, nws raug muab sib xyaw nrog ib yam tshuaj hu ua carbidopa los txwv nws. | Qhov no yog cov tshuaj tseem ceeb thiab zoo tshaj plaws rau tus kab mob Parkinson. Nws zoo heev rau kev txo qhov kev txav qeeb (bradykinesia), kev tawv nqaij tsis khov, thiab kev tshee hnyo. |
| Cov tshuaj dopamine agonists | Cov no ua rau cov dopamine receptors hauv lub hlwb ua haujlwm thiab "ua haujlwm" zoo li dopamine. Uas yog, cov tshuaj no ua tib yam li dopamine ua. | Feem ntau siv rau theem pib ntawm tus kab mob lossis rau cov neeg mob hluas dua, nws kuj pab tswj hwm qhov ua tau zoo ntawm levodopa rau lub sijhawm ntev dua. |
| Cov Tshuaj Enzyme Inhibitors (MAO-B & COMT) | Cov tshuaj no txo cov haujlwm ntawm cov enzymes hauv lub hlwb uas rhuav tshem dopamine, ua rau dopamine nyob hauv lub hlwb ntev dua. | Cov no yog muab los pab ua kom cov nyhuv ntawm levodopa ntau ntxiv thiab ua kom nws kav ntev dua. |
| Amantadine | Nws pab tswj dyskinesia, uas yog kev co lossis kev co ntawm lub cev uas tsis tuaj yeem tswj tau uas tuaj yeem tshwm sim los ntawm cov tshuaj xws li levodopa. | Txawm hais tias thawj zaug pom tias yog tshuaj tua kab mob, nws kuj tseem muaj txiaj ntsig zoo rau lwm yam kev txav mus los xws li tus kab mob Parkinson. |
| Cov tshuaj Anticholinergic | Thaum dopamine txo qis, cov teebmeem ntawm lwm yam tshuaj hu ua acetylcholine nce ntxiv. Cov tshuaj no thaiv nws cov teebmeem, txo qhov tshee thiab cov leeg nqaij tawv. | Nws yuav pab tau rau cov neeg mob uas muaj kev co ntau dhau. |
Qhov tseem ceeb tshaj plaws yog tsuas yog koj tus kws kho mob thiaj li txiav txim siab tau tias yuav muab cov tshuaj twg thiab muab ntau npaum li cas. Nws nyob ntawm tus neeg mob lub hnub nyoog, qhov xwm txheej ntawm cov tsos mob, thiab ntau lwm yam.
Peb puas yuav tsum paub txog cov kev mob tshwm sim ntawm cov tshuaj?
Ib yam li lwm yam tshuaj, cov tshuaj Parkinson tuaj yeem muaj cov kev mob tshwm sim. Cov no sib txawv nyob ntawm hom tshuaj. Tsis txhob txhawj, tsis yog txhua tus yuav tau txais tag nrho cov kev mob tshwm sim no. Tab sis nws yog ib qho tseem ceeb kom paub txog lawv.
- Levodopa: Tej zaum yuav muaj xeev siab, ntuav, kiv taub hau, mob taub hau, tsaug zog thaum nruab hnub, thiab tsis muaj zog ntawm lub cev thaum pib kho mob. Rau cov neeg laus, tej zaum yuav muaj kev tsis meej pem, pom tej yam tsis muaj tseeb, lossis muaj kev puas siab puas ntsws.
- Cov Tshuaj Dopamine Agonists: Cov no tuaj yeem ua rau xeev siab, tsaug zog, qhov ncauj qhuav, tsis meej pem, thiab pom kev tsis tseeb thaum koj pib noj lawv. Txawm li cas los xij, cov tsos mob no feem ntau ploj mus hauv ob peb hnub.
- Lwm cov tshuaj: Qee cov tshuaj yuav ua rau muaj kev phiv xws li raws plab, mob hauv siab, pw tsis tsaug zog, o ceg, cem quav, lossis qhov ncauj qhuav.
Ib qho lus ceeb toom tseem ceeb heev: Tsis txhob tsum noj levodopa lossis txo qhov koob tshuaj sai sai yam tsis tau sab laj nrog koj tus kws kho mob. Ua li ntawd tuaj yeem ua rau muaj mob txaus ntshai heev, uas hu ua Parkinsonism Hyperpyrexia Syndrome. Nws yog ib qho mob hnyav zoo ib yam li Neuroleptic Malignant Syndrome. Yog tias koj xav tau tsum tsis txhob noj tshuaj rau txhua qhov laj thawj, nco ntsoov nrog koj tus kws kho mob tham.
Puas muaj tshuaj rau lwm cov tsos mob uas tsis cuam tshuam nrog kev txav mus los?
Yog. Parkinson's tsis yog ib yam kab mob uas cuam tshuam rau kev txav mus los xwb. Tab sis kuj muaj ntau yam teeb meem uas los nrog nws. Tus kws kho mob kuj tuaj yeem kho cov ntawd thiab.
| Cov tsos mob | Cov Kev Kho Mob Uas Muaj Peev Xwm Ua Tau |
|---|---|
| Kab mob cem quav | Cov tshuaj uas pab kom yooj yim tso quav, xws li polyethylene glycol (xws li MiraLax). |
| Kev tsaug zog thaum nruab hnub | Cov tshuaj xws li Modafinil (xws li Provigil). |
| Kev Nyuaj Siab Los Yog Kev Ntxhov Siab | Cov tshuaj antidepressants hom SSRI. |
| Kev puas siab puas ntsws/Kev pom tsis tseeb | Cov tshuaj tiv thaiv kev puas siab puas ntsws tshwj xeeb xws li pimavanserin. |
| Kev Ua Tsis Taus Erectile | Cov tshuaj Sildenafil (zoo li Viagra). |
Yuav ua li cas ntxiv rau kev siv tshuaj?
Tshuaj tsuas yog ib feem ntawm qhov kev sib ntaus sib tua no xwb. Tsis tas li ntawd xwb, muaj ntau yam uas tuaj yeem txhim kho tus neeg mob lub neej zoo.
Kev tawm dag zog thiab kev kho lub cev yog qhov tseem ceeb heev rau kev tswj tus kab mob Parkinson. Qhov tseeb, kev tawm dag zog yog tib yam uas tau ua pov thawj tias ua rau tus kab mob qeeb zuj zus.
- Kev Kho Mob Lub Cev: Cov kev pab cuam kho mob lub cev uas tsim tshwj xeeb rau cov neeg mob Parkinson tuaj yeem txhim kho kev sib npaug, kev taug kev, thiab kev ruaj khov.
- Kev Ua Si: Nws yog ib qho tseem ceeb heev uas yuav tsum ua tsawg kawg 150 feeb ntawm kev tawm dag zog rau lub plawv thiab cov hlab ntsha hauv ib lub lim tiam. Cov kev ua si xws li kev caij tsheb kauj vab thiab kev ntaus nrig tau pom tias muaj txiaj ntsig zoo heev.
- Kev Noj Qab Haus Huv Lub Siab: Kev nyob nrog tus kab mob ntev xws li Parkinson's tuaj yeem ua rau lub siab nyuaj. Yog li ntawd, yog tias koj tu siab lossis ntxhov siab, tsis txhob yig tham nrog tus kws kho mob lub siab, xws li tus kws kho mob hlwb.
Kuv yuav tsum mus ntsib kws kho mob dua thaum twg?
Thaum noj tshuaj Parkinson, nws yog ib qho tseem ceeb uas yuav tsum mus ntsib koj tus kws kho mob tsis tu ncua kom paub seb cov tshuaj puas ua haujlwm thiab yog tias koj muaj cov tsos mob tshiab. Nco ntsoov nrog koj tus kws kho mob tham, tshwj xeeb tshaj yog thaum muaj cov xwm txheej zoo li no.
- Yog tias koj ntsib cov kev mob tshwm sim uas koj tsis tuaj yeem zam tau.
- Yog tias koj cov tsos mob tsis zoo dua lossis hnyav zuj zus.
- Yog koj xav tsum tsis txhob noj tshuaj.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Txawm hais tias tus kab mob Parkinson tsis tuaj yeem kho tau tag nrho los xij, cov tsos mob tuaj yeem tswj tau zoo heev thiab koj tuaj yeem ua neej zoo.
- Levodopa yog cov tshuaj tseem ceeb thiab zoo tshaj plaws rau tus kab mob no.
- Tsis txhob tsum noj tshuaj lossis hloov qhov ntau npaum li cas rau txhua qhov laj thawj yam tsis tau koj tus kws kho mob qhia.
- Kev tawm dag zog thiab kev kho lub cev tseem ceeb npaum li kev siv tshuaj. Kev tawm dag zog tuaj yeem pab tswj kev loj hlob ntawm tus kab mob.
- Yog koj muaj tej yam tshwm sim los yog lwm yam teeb meem, tsis txhob ntshai tham nrog koj tus kws kho mob. Nws yeej ib txwm npaj pab koj.
💬 Comments (0)
Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus